Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Foxf2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FOXF2 mRNA | CTD | PMID:24058054 and PMID:26377647 | Foxf2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FOXF2 mRNA | CTD | PMID:29704546 | Foxf2 | Mouse | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | FOXF2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FOXF2 mRNA | CTD | PMID:28628672 | Foxf2 | Mouse | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of FOXF2 mRNA | CTD | PMID:30951980 | Foxf2 | Mouse | aflatoxin B1 | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of FOXF2 mRNA | CTD | PMID:22100608 | Foxf2 | Mouse | aflatoxin B1 | increases methylation | ISO | FOXF2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of FOXF2 gene | CTD | PMID:28458013 | Foxf2 | Mouse | aflatoxin B1 | decreases methylation | ISO | FOXF2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FOXF2 gene | CTD | PMID:27153756 | Foxf2 | Mouse | Aflatoxin B2 alpha | increases methylation | ISO | FOXF2 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of FOXF2 intron | CTD | PMID:30157460 | Foxf2 | Mouse | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FOXF2 mRNA | CTD | PMID:37567420 | Foxf2 | Mouse | arsenite(3-) | increases methylation | ISO | FOXF2 (Homo sapiens) | 6480464 | arsenite results in increased methylation of FOXF2 promoter | CTD | PMID:23974009 | Foxf2 | Mouse | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to FOXF2 promoter] | CTD | PMID:19654925 | Foxf2 | Mouse | benzo[a]pyrene | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FOXF2 mRNA | CTD | PMID:32234424 | Foxf2 | Mouse | benzo[a]pyrene | affects methylation | ISO | FOXF2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FOXF2 exon | CTD | PMID:27901495 | Foxf2 | Mouse | benzo[a]pyrene | increases methylation | ISO | FOXF2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of FOXF2 3' UTR and Benzo(a)pyrene results in increased methylation of FOXF2 promoter | CTD | PMID:27901495 | Foxf2 | Mouse | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of FOXF2 mRNA | CTD | PMID:21569818 | Foxf2 | Mouse | bisphenol A | affects methylation | EXP | | 6480464 | bisphenol A affects the methylation of FOXF2 promoter | CTD | PMID:27334623 | Foxf2 | Mouse | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FOXF2 mRNA | CTD | PMID:30951980 | Foxf2 | Mouse | bisphenol F | multiple interactions | ISO | FOXF2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FOXF2 mRNA | CTD | PMID:28628672 | Foxf2 | Mouse | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of FOXF2 mRNA | CTD | PMID:30951980 | Foxf2 | Mouse | buta-1,3-diene | decreases expression | EXP | | 6480464 | 1 and 3-butadiene results in decreased expression of FOXF2 mRNA | CTD | PMID:29038090 | Foxf2 | Mouse | cadmium atom | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Cadmium results in increased expression of FOXF2 mRNA | CTD | PMID:24376830 | Foxf2 | Mouse | cadmium atom | decreases activity | EXP | | 6480464 | Cadmium results in decreased activity of FOXF2 protein | CTD | PMID:33642518 | Foxf2 | Mouse | calcitriol | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of FOXF2 mRNA | CTD | PMID:26485663 | Foxf2 | Mouse | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Foxf2 | Mouse | carmustine | affects response to substance | ISO | FOXF2 (Homo sapiens) | 6480464 | FOXF2 mRNA affects the susceptibility to Carmustine | CTD | PMID:16365179 | Foxf2 | Mouse | CGP 52608 | multiple interactions | ISO | FOXF2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to FOXF2 gene] | CTD | PMID:28238834 | Foxf2 | Mouse | chloroprene | decreases expression | EXP | | 6480464 | Chloroprene results in decreased expression of FOXF2 mRNA | CTD | PMID:23125180 | Foxf2 | Mouse | cisplatin | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of FOXF2 mRNA | CTD | PMID:19561079 | Foxf2 | Mouse | cisplatin | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of FOXF2 mRNA | CTD | PMID:27392435 | Foxf2 | Mouse | cisplatin | multiple interactions | ISO | FOXF2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of FOXF2 mRNA | CTD | PMID:27392435 | Foxf2 | Mouse | copper(II) sulfate | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of FOXF2 mRNA | CTD | PMID:19549813 | Foxf2 | Mouse | CU-O LINKAGE | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | cupric oxide results in decreased expression of FOXF2 mRNA | CTD | PMID:22077320 | Foxf2 | Mouse | curcumin | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Curcumin results in decreased expression of FOXF2 mRNA | CTD | PMID:15713895 | Foxf2 | Mouse | cypermethrin | decreases expression | ISO | Foxf2 (Rattus norvegicus) | 6480464 | cypermethrin results in decreased expression of FOXF2 mRNA | CTD | PMID:22528246 | Foxf2 | Mouse | D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FOXF2 mRNA | CTD | PMID:37567420 | Foxf2 | Mouse | dexamethasone | multiple interactions | ISO | FOXF2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FOXF2 mRNA | CTD | PMID:28628672 | Foxf2 | Mouse | dibenz[a,h]anthracene | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | 1 more ... | CTD | PMID:27322209 | Foxf2 | Mouse | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of FOXF2 mRNA | CTD | PMID:30529165 | Foxf2 | Mouse | elemental selenium | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Selenium results in decreased expression of FOXF2 mRNA | CTD | PMID:19244175 | Foxf2 | Mouse | etoposide | affects response to substance | ISO | FOXF2 (Homo sapiens) | 6480464 | FOXF2 protein affects the susceptibility to Etoposide | CTD | PMID:16217747 | Foxf2 | Mouse | fluoranthene | multiple interactions | EXP | | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of FOXF2 mRNA | CTD | PMID:28329830 | Foxf2 | Mouse | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of FOXF2 mRNA | CTD | PMID:25629700 | Foxf2 | Mouse | fructose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FOXF2 mRNA | CTD | PMID:37567420 | Foxf2 | Mouse | glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FOXF2 mRNA | CTD | PMID:37567420 | Foxf2 | Mouse | hydrogen peroxide | multiple interactions | ISO | FOXF2 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FOXF2 protein | CTD | PMID:18951874 | Foxf2 | Mouse | indometacin | multiple interactions | ISO | FOXF2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FOXF2 mRNA | CTD | PMID:28628672 | Foxf2 | Mouse | methylmercury chloride | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of FOXF2 mRNA | CTD | PMID:28001369 | Foxf2 | Mouse | mitoxantrone | affects response to substance | ISO | FOXF2 (Homo sapiens) | 6480464 | FOXF2 protein affects the susceptibility to Mitoxantrone | CTD | PMID:16217747 | Foxf2 | Mouse | N-ethyl-N-nitrosourea | increases mutagenesis | EXP | | 6480464 | Ethylnitrosourea results in increased mutagenesis of FOXF2 gene | CTD | PMID:16724327 | Foxf2 | Mouse | nickel sulfate | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of FOXF2 mRNA | CTD | PMID:22714537 | Foxf2 | Mouse | selenium atom | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Selenium results in decreased expression of FOXF2 mRNA | CTD | PMID:19244175 | Foxf2 | Mouse | serpentine asbestos | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Asbestos and Serpentine results in increased expression of FOXF2 mRNA | CTD | PMID:21148743 | Foxf2 | Mouse | silicon dioxide | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of FOXF2 mRNA | CTD | PMID:25895662 | Foxf2 | Mouse | sodium arsenite | increases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of FOXF2 mRNA | CTD | PMID:28595984 | Foxf2 | Mouse | sodium arsenite | affects expression | ISO | FOXF2 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of FOXF2 mRNA | CTD | PMID:34032870 | Foxf2 | Mouse | temozolomide | affects response to substance | ISO | FOXF2 (Homo sapiens) | 6480464 | FOXF2 mRNA affects the susceptibility to temozolomide | CTD | PMID:16365179 | Foxf2 | Mouse | theophylline | multiple interactions | ISO | FOXF2 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FOXF2 protein | CTD | PMID:18951874 | Foxf2 | Mouse | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of FOXF2 mRNA | CTD | PMID:29264374 | Foxf2 | Mouse | triclosan | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of FOXF2 mRNA | CTD | PMID:30510588 | Foxf2 | Mouse | trimellitic anhydride | decreases expression | EXP | | 6480464 | trimellitic anhydride results in decreased expression of FOXF2 mRNA | CTD | PMID:19042947 | Foxf2 | Mouse | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of FOXF2 mRNA | CTD | PMID:17292431 | Foxf2 | Mouse | valproic acid | increases methylation | ISO | FOXF2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of FOXF2 gene | CTD | PMID:29154799 | Foxf2 | Mouse | valproic acid | affects expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FOXF2 mRNA | CTD | PMID:25979313 | Foxf2 | Mouse | vitamin E | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of FOXF2 mRNA | CTD | PMID:19244175 | Foxf2 | Mouse | zinc atom | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Zinc results in decreased expression of FOXF2 mRNA | CTD | PMID:19071009 | Foxf2 | Mouse | zinc(0) | decreases expression | ISO | FOXF2 (Homo sapiens) | 6480464 | Zinc results in decreased expression of FOXF2 mRNA | CTD | PMID:19071009 | |