Foxl1 (forkhead box L1) - Rat Genome Database

Name: Foxl1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Foxl1 (forkhead box L1) Mus musculus

Analyze

Symbol:

Foxl1

Name:

forkhead box L1

RGD ID:

1614457

MGI Page

MGI

Description:

Enables DNA-binding transcription factor activity. Acts upstream of or within several processes, including Peyer's patch morphogenesis; proteoglycan biosynthetic process; and visceral mesoderm-endoderm interaction involved in midgut development. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; sensory organ; and urinary system. Orthologous to human FOXL1 (forkhead box L1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

fkh-6; Fkh6; forkhead box protein L1; forkhead homolog 6; forkhead-related protein FKHL11; FREA; FREAC7; transcription factor FKH-6

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FOXL1 (forkhead box L1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Rattus norvegicus (Norway rat):	Foxl1 (forkhead box L1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FOXL1 (forkhead box L1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FOXL1 (forkhead box L1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Foxl1 (forkhead box L1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FOXL1 (forkhead box L1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FOXL1 (forkhead box L1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Foxl1 (forkhead box L1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	FOXL1 (forkhead box L1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Foxl1 (forkhead box L1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	foxl1 (forkhead box L1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	FoxL1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	HCM1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER)
Caenorhabditis elegans (roundworm):	fkh-6	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	foxl1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	121,854,572 - 121,857,383 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	121,854,679 - 121,857,383 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	121,127,685 - 121,130,644 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	121,127,940 - 121,130,644 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	123,651,585 - 123,654,544 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	124,013,939 - 124,014,949 (+)	NCBI		MGSCv36	mm8
Celera	8	125,345,766 - 125,348,725 (+)	NCBI		Celera
Cytogenetic Map	8	E1	NCBI
cM Map	8	70.34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Otosclerosis 11 (ISO)

persistent fetal circulation syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

all-trans-retinoic acid (ISO)

amosite asbestos (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

butanal (ISO)

carbon nanotube (EXP)

choline (EXP)

clofibrate (EXP)

crocidolite asbestos (ISO)

folic acid (EXP)

L-methionine (EXP)

leflunomide (ISO)

lipopolysaccharide (EXP)

methylisothiazolinone (ISO)

N-Nitrosopyrrolidine (ISO)

niclosamide (ISO)

paracetamol (EXP)

resveratrol (ISO)

sodium arsenite (ISO)

trichloroethene (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anatomical structure morphogenesis (IBA)

cell differentiation (IBA)

heart development (ISO)

Peyer's patch morphogenesis (IMP)

proteoglycan biosynthetic process (IMP)

regulation of DNA-templated transcription (TAS)

regulation of transcription by RNA polymerase II (IBA)

regulation of Wnt signaling pathway (IMP)

visceral mesoderm-endoderm interaction involved in midgut development (IMP)

Cellular Component

nucleus (IEA)

Molecular Function

DNA binding (ISO)

DNA-binding transcription factor activity (IDA,TAS)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific DNA binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal cell physiology (IAGP)

abnormal crypts of Lieberkuhn morphology (IAGP)

abnormal digestive secretion (IAGP)

abnormal gastric chief cell morphology (IAGP)

abnormal gastric gland morphology (IAGP)

abnormal gastric parietal cell morphology (IAGP)

abnormal intestinal epithelium morphology (IAGP)

abnormal intestinal goblet cell morphology (IAGP)

abnormal jejunum morphology (IAGP)

abnormal pyloric gastric gland morphology (IAGP)

abnormal small intestinal villus morphology (IAGP)

abnormal small intestine crypts of Lieberkuhn morphology (IAGP)

abnormal stomach glandular epithelium morphology (IAGP)

abnormal stomach morphology (IAGP)

abnormal stomach mucosa morphology (IAGP)

colon polyps (IAGP)

decreased body size (IAGP)

decreased small intestinal villus size (IAGP)

delayed intestine development (IAGP)

ectopic Paneth cells (IAGP)

gastric polyps (IAGP)

increased colon adenoma incidence (IAGP)

increased stomach mucosa thickness (IAGP)

postnatal growth retardation (IAGP)

postnatal lethality, incomplete penetrance (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7689224	PMID:7957066	PMID:8674414	PMID:9203584	PMID:10349636	PMID:10615124	PMID:10926756	PMID:11042159	PMID:11076861	PMID:11162636	PMID:11217851	PMID:11555641
PMID:12466851	PMID:12477932	PMID:12648490	PMID:12812790	PMID:14681479	PMID:15155178	PMID:15188402	PMID:15240114	PMID:15618518	PMID:15650110	PMID:16141072	PMID:16141073
PMID:16230531	PMID:16469829	PMID:16618389	PMID:18287559	PMID:19049965	PMID:19105206	PMID:19841618	PMID:20059953	PMID:21873635	PMID:22988430	PMID:23226461	PMID:23369715
PMID:24952961	PMID:25286440	PMID:27736991	PMID:28506991	PMID:28797033	PMID:28867346	PMID:28994389	PMID:30916783	PMID:33993983	PMID:34029742	PMID:34671097	PMID:37028407

Genomics

Comparative Map Data

Foxl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	121,854,572 - 121,857,383 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	121,854,679 - 121,857,383 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	121,127,685 - 121,130,644 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	121,127,940 - 121,130,644 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	123,651,585 - 123,654,544 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	124,013,939 - 124,014,949 (+)	NCBI		MGSCv36	mm8
Celera	8	125,345,766 - 125,348,725 (+)	NCBI		Celera
Cytogenetic Map	8	E1	NCBI
cM Map	8	70.34	NCBI

FOXL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	86,578,549 - 86,583,478 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	86,576,368 - 86,583,478 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	86,612,155 - 86,617,084 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	85,169,616 - 85,172,805 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	85,169,830 - 85,170,868	NCBI
Celera	16	70,913,076 - 70,916,265 (+)	NCBI		Celera
Cytogenetic Map	16	q24.1	NCBI
HuRef	16	72,351,923 - 72,355,112 (+)	NCBI		HuRef
CHM1_1	16	88,023,838 - 88,027,027 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	92,646,860 - 92,651,789 (+)	NCBI		T2T-CHM13v2.0

Foxl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	19	49,197,269 - 49,200,682 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	49,197,400 - 49,198,425 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	55,988,536 - 55,991,947 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	56,672,265 - 56,675,680 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	58,886,722 - 58,890,133 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	53,054,887 - 53,058,624 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	53,055,745 - 53,056,770 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	63,799,271 - 63,802,117 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	19	48,442,841 - 48,446,578 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

FOXL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	16	102,251,825 - 102,256,791 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	67,249,157 - 67,252,278 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	86,580,646 - 86,583,593 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

FOXL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	66,281,543 - 66,287,357 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	66,283,528 - 66,284,598 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	66,293,564 - 66,299,385 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	66,503,066 - 66,508,886 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	66,505,053 - 66,506,123 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	66,525,951 - 66,531,764 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	66,361,136 - 66,366,956 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	66,774,376 - 66,780,196 (-)	NCBI		UU_Cfam_GSD_1.0

Foxl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	26,471,248 - 26,476,373 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936641	2,226,550 - 2,227,578 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936641	2,226,489 - 2,227,613 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FOXL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	2,542,675 - 2,543,691 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	2,540,748 - 2,544,978 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	2,748,329 - 2,750,723 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FOXL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	71,960,154 - 71,968,629 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	71,963,965 - 71,965,002 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	3,739,091 - 3,744,440 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Foxl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	2,642,691 - 2,643,731 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624746	2,640,486 - 2,645,326 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Foxl1
122 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	734
Count of miRNA genes:	466
Interacting mature miRNAs:	556
Transcripts:	ENSMUST00000062634, ENSMUST00000181609
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357708	Orq1_m	ovulation rate QTL 1 (mouse)			Not determined		8	71740461	124622354	Mouse
4142023	W3q5_m	weight 3 weeks QTL 5 (mouse)			Not determined			71740461	124622354	Mouse
27095912	Pglq14_m	pelvic girdle length QTL 14, 16 week (mouse)					8	74126628	126826739	Mouse
27226796	Scvln16_m	sacral vertebrae length 2, 16 week (mouse)					8	89726628	130027694	Mouse
1357494	Obsty2_m	obesity 2 (mouse)			Not determined		8	96245241	129745061	Mouse
12880431	Fgf23lq2_m	FGF23 serum level QTL 2 (mouse)					8	97626632	130127694	Mouse
11252141	Fdr2_m	fat response to dietary restriction 2 (mouse)					8	98390634	130127694	Mouse
1301481	Lith11_m	lithogenic gene 11 (mouse)			Not determined		8	98563635	130127694	Mouse
1302105	Im1_m	Immunoregulatory 1 (mouse)			Not determined		8	99828531	130127694	Mouse
1301080	Sluc9_m	susceptibility to lung cancer 9 (mouse)			Not determined		8	99828531	130127694	Mouse
4141435	Fbtq3_m	femoral bone trait QTL 3 (mouse)			Not determined		8	100965309	130127694	Mouse
1301316	Dntcs1_m	dental caries susceptibility 1 (mouse)			Not determined		8	103443553	127781786	Mouse
11532691	Sluc38_m	susceptibility to lung cancer 38 (mouse)					8	105033977	130127694	Mouse
11532692	Sluc38a_m	susceptibility to lung cancer 38a (mouse)					8	105033977	130127694	Mouse
14746994	Manh65_m	mandible shape 65 (mouse)					8	106489629	130127694	Mouse
10412273	Fcd1_m	functional capillary density 1 (mouse)			Not determined		8	110415083	130127694	Mouse
10412274	Leci1_m	leukocyte endothelial cell interactions 1 (mouse)			Not determined		8	110415083	130127694	Mouse
12904938	Edlmmq7_m	extensor digitorum longus muscle mass QTL 7 (mouse)					8	111481497	130127694	Mouse
12904960	Gmmq6_m	gastrocnemius muscle mass QTL 6 (mouse)					8	111481497	130127694	Mouse
4141546	Mrdq3_m	modifier of retinal degeneration QTL 3 (mouse)			Not determined			114439420	126055880	Mouse
26884375	Skwq2_m	skull length QTL 2, 5 week (mouse)					8	120726739	130027694	Mouse

Markers in Region

X92498

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	121,129,125 - 121,129,324	UniSTS	GRCm38
MGSCv37	8	123,653,025 - 123,653,224	UniSTS	GRCm37
Celera	8	125,347,206 - 125,347,405	UniSTS
Cytogenetic Map	8	E1	UniSTS
cM Map	8	65.5	UniSTS
Whitehead/MRC_RH	8	1416.9	UniSTS

Foxl1

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	121,128,371 - 121,128,968	UniSTS	GRCm38
MGSCv37	8	123,652,271 - 123,652,868	UniSTS	GRCm37
Celera	8	125,346,452 - 125,347,049	UniSTS
Cytogenetic Map	8	E1	UniSTS
cM Map	8	65.5	UniSTS

Foxd4

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	24,901,109 - 24,901,895	UniSTS	GRCm38
MGSCv37	19	24,975,599 - 24,976,385	UniSTS	GRCm37
Celera	19	25,676,309 - 25,677,094	UniSTS
Cytogenetic Map	8	E1	UniSTS
Cytogenetic Map	19	B	UniSTS
cM Map	8	65.5	UniSTS
cM Map	19	17.5	UniSTS

UniSTS:491230

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	121,127,940 - 121,129,029	UniSTS	GRCm38
MGSCv37	8	123,651,840 - 123,652,929	UniSTS	GRCm37
Celera	8	125,346,021 - 125,347,110	UniSTS
Cytogenetic Map	8	E1	UniSTS
cM Map	8	65.5	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_008024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB221616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC127554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK050949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466525	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X71944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92498	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000181609 ⟹ ENSMUSP00000137732

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	121,854,679 - 121,857,383 (+)	Ensembl
GRCm38.p6 Ensembl	8	121,127,940 - 121,130,644 (+)	Ensembl

RefSeq Acc Id:

NM_008024 ⟹ NP_032050

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	121,854,572 - 121,857,383 (+)	NCBI
GRCm38	8	121,127,685 - 121,130,644 (+)	ENTREZGENE
MGSCv37	8	123,651,585 - 123,654,544 (+)	RGD
Celera	8	125,345,766 - 125,348,725 (+)	RGD
cM Map	8		ENTREZGENE

Sequence:

show sequence

AGATTTTCAGCAATGAAATTTTAATTAATGTGGGTGGGCTGAGAACACAAGGACTGTTTATCAT
AGACAATTTATTTTCCAGCGCTAAGTCAACACATAATAGCAAACTTACAACAATTATTTAACAT
TTTTAAAGCCATGAAGAAGGGACAAAGCGCGCAGCGGCTGGGGAGAGCGGCTGATCGCAGGGCA
GTCGCACAGAGGGCTCCCCAGGAGGGCCCTGGTGCGGGGCAAAGTCCTTAGGACTCCCCGGTGG
AGCGGAGAGGCTGCTGTCGCCATGAGCCACCTCTTCAGTCCCCCGCTGGCCGCTCTGGCAGCCT
CGCCGCTGTTGTACGTGTACAGCCCCGAGAGGCCTGGGCTGCCCCTGGCCTTCGCCCCTGCGGC
TGCACTGGCCGGCCCGGGCCGCGTCGAGCCCCCGCAGAAGCCGCCCTACAGCTACATCGCTCTT
ATAGCCATGGCGATCCAGGATGCTCCCGAGCAGAGGGTCACACTGAACGGCATCTACCAGTTCA
TCATGGATCGCTTCCCGTTCTACCACGACAACCGCCAAGGCTGGCAGAACAGCATCCGCCACAA
CCTGTCGCTCAACGAGTGCTTCGTGAAGGTGCCACGTGAGAAGGGGCGGCCGGGCAAGGGCAGC
TACTGGACCCTGGACCCCCGCTGCTTGGACATGTTTGAGAACGGCAATTATCGGCGCAGGAAGA
GGAAGCCCAAGCCCGCCGCGGGTTCCCCGGAGGCCAAGCGCACCCGGGTCGAGCCGCCGGAGTC
CGAGGTGGGCTGCGATGTAGGGTCCCCGGACCTGGCCACTGCACTCCCGACGCGCGCGCCGGAT
CGCTCCCAATCCCCGGCAGTAGGCACCGCGCGGCCCGCGCTCCTTCCCTGGCCCGGCCCTGAGC
CCCGGGACCCCGACGCGGACCTCACAGTCCAGGGCGCAGGGGCAGTGGCAAGCGGCCAGCTCCA
GCGTCCGGCACACCACCTGGGGTCCCCTCTGTGCCCCGCCCCCAGCGGCTCCCCAAAAGGTTCC
AAGTCAAAGAGTTTCAGCATCGACAGCATCTTGGCCGTGAGACCGACGCCAGCCTCAGGGGCCG
AAGCACCGGGGATCCCTAAGCCCGTGCCTGGCGCGCTGGGCTCCTCTCTGCTGGCTGCCTCCTC
CGGCCTAGCGCCTCCCTTCAACGCTTCGCTGGTCTTCGACGCGCACGTCCAGGGCGGCTTTTCC
CAGCTGGGGATTCCCTTCCTTTCTTATTTTCCTCTGCAGGTTCCCGAGGCCACAGTGCTTCGTT
TCCACTAAGGCGGATTAGCGGCTGCTTCCCTGCCTCGCGATCCCCCCACCTCCAGTGAGCCAAT
GCCTGTGGGCGAAGGAGTCGCCCCGGTCTCTGCCCTGGCAGAGACTGAGGGTTTGGAGCAGCGT
ACCCGTGCCGGCCAAAGTCGTGCACTGAGGGGCCTCGTCCATCTGCTTTCTCCGAAGATGACTT
AACCAGCCACCGGAAGCTTTGCAGATTTAAAAGACTGGTCCAGTAGAGGACATGGTCGCCGCAC
ACTCAGCCCTCACGGTTCGTCTCCAGCAGAAGCCCCTCGTAGGCTTTGGCGGCGTTGTACAGTG
ACCACCACAAGTCCCCACTCGGACCTGAGTCTCCTGCTGACCCTGAGGGCAGGACTTAGAGATA
TAGCGAACAGCTCTATGTGGAGGTTCAACTGGATCATGGAAGGCTCAGCGGGCTCCGTGTGGCA
TAGGCCTTGGCTTTGATCTCATTGGATGTGGGGAGCTTGCAGCCAGGATGCTGGGGATGATCCG
TGGTCCGCAGGCTCTGGGAAAGATGTAGGCCTGGTTAACGTTTACAACTAAGGTTGAACAAAAG
CAGGCTCACCGGAAATGCTCAATATGAATAGATAAACCTTCTTCCAGACAGGGAAAGGCTCATT
TATTCTTGGCTTATAAACCAGGCTCCCCTTTGCTATAGCTAGTAGCTTCTTTTAAGGAGCCCCG
TGTGTTTGGCACGTACTTTGGCTTTACAGTGGCACACCTGCCGCATTCCACAGCATAGTCCTCT
GTTCACTTCTGCTTTTCTTTTCTTTTTTTTTTTTTGTGTGGGGGGGAGGGGTTCGAGACAGGGT
TTCTCTGTATAGCCCTGGCTGTCCTGGAACTCACTTTGTAGACCAGGCTGGCCTGCCTCTGCCT
CCCGAGAGCTGGGATTAAAGGCGTACTCCACCATGCCTGGCCTGCTTTTCTTTTTAAGGCACCA
AAAAATTTCAGGGGACACAGAAGGGTGTGTGATCGGAGGGATTATTATGACTCAAGGGCGGGTT
TTTTTTTTAACTTCTGTAGCTTTTTAAGATCTAAGTCCCCCCCCCATCTCTCTCCCCCCCCCCA
CTCACACTTTCCAGAAACACACACACAGTGAAGGACTACATGTAATCAGAGAGGCTGGGGGAGC
ATACTACTCCTGAGTGTGGGAGATAGATAGCTTCCAGGAGTGACAGGGACTCTCTTCAGACAAA
GCCTGTGGTACCTCAAGTCTGTGTTCCCTTTATATCCCTCCAGGGAGATCTAGATATTGACATT
ACATAAACCCATAAGAGGTGACCAGAGAGCGGGGTTGAGGGGGAGGGGGTGGGGAGATCAACAA
AGTGCTGACTAAGGCAACTAAGTTGGTTACCGTGCAGTGCAGTCCTGCTTCCAAATTTGGGGGA
AACTCTCAGGCCTTTGGGGTGCCCATGTTTAAGCTTGCTGGTGGGCTCTGCAACTCAGCTTTCA
GAGGAAGGAAAGTGCTGGTCCTTGATGTAAAAAAAAGGACCAAAAATTAAGAATTCTAGGGCAT
AGGTCCACAGTGATGTCTCACAACAACTAAGGTATGCCGTGCATCACACCTGTAATCTCAGTCC
TTGCAAGGCTGAGGCAGGGGGATTGCTGTGAGTTTAAGGATAGCTTGTGGCACAGAGTTAGACA
TGTCTCAAACTAAGGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_032050	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI37806	(Get FASTA)	NCBI Sequence Viewer
	AAI37807	(Get FASTA)	NCBI Sequence Viewer
	BAC34473	(Get FASTA)	NCBI Sequence Viewer
	CAA50746	(Get FASTA)	NCBI Sequence Viewer
	CAA63243	(Get FASTA)	NCBI Sequence Viewer
	EDL11654	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000137732
GenBank Protein	Q64731	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_032050 ⟸ NM_008024

- UniProtKB:

B2RQ86 (UniProtKB/Swiss-Prot), Q64731 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MSHLFSPPLAALAASPLLYVYSPERPGLPLAFAPAAALAGPGRVEPPQKPPYSYIALIAMAIQD
APEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNECFVKVPREKGRPGKGSYWTLDPR
CLDMFENGNYRRRKRKPKPAAGSPEAKRTRVEPPESEVGCDVGSPDLATALPTRAPDRSQSPAV
GTARPALLPWPGPEPRDPDADLTVQGAGAVASGQLQRPAHHLGSPLCPAPSGSPKGSKSKSFSI
DSILAVRPTPASGAEAPGIPKPVPGALGSSLLAASSGLAPPFNASLVFDAHVQGGFSQLGIPFL
SYFPLQVPEATVLRFH

hide sequence

RefSeq Acc Id:

ENSMUSP00000137732 ⟸ ENSMUST00000181609

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q64731-F1-model_v2	AlphaFold	Q64731	1-336	view protein structure

Promoters

RGD ID:

8668481

Promoter ID:

EPDNEW_M12271

Type:

multiple initiation site

Name:

Foxl1_1

Description:

Mus musculus forkhead box L1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	8	121,127,854 - 121,127,914	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1347469	AgrOrtholog
Ensembl Genes	ENSMUSG00000097084	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000181609	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.10.10	UniProtKB/Swiss-Prot
InterPro	FH_FOXL1	UniProtKB/Swiss-Prot
	Fork_head_dom	UniProtKB/Swiss-Prot
	TF_fork_head_CS_1	UniProtKB/Swiss-Prot
	TF_fork_head_CS_2	UniProtKB/Swiss-Prot
	WH-like_DNA-bd_sf	UniProtKB/Swiss-Prot
	WH_DNA-bd_sf	UniProtKB/Swiss-Prot
KEGG Report	mmu:14241	UniProtKB/Swiss-Prot
MGD	MGI:1347469	ENTREZGENE
NCBI Gene	14241	ENTREZGENE
PANTHER	FORKHEAD BOX PROTEIN	UniProtKB/Swiss-Prot
	FORKHEAD BOX PROTEIN L1	UniProtKB/Swiss-Prot
Pfam	Forkhead	UniProtKB/Swiss-Prot
PhenoGen	Foxl1	PhenoGen
PRINTS	FORKHEAD	UniProtKB/Swiss-Prot
PROSITE	FORK_HEAD_1	UniProtKB/Swiss-Prot
	FORK_HEAD_2	UniProtKB/Swiss-Prot
	FORK_HEAD_3	UniProtKB/Swiss-Prot
SMART	SM00339	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46785	UniProtKB/Swiss-Prot
UniProt	B2RQ86	ENTREZGENE
	FOXL1_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8BQE0_MOUSE	UniProtKB/TrEMBL
UniProt Secondary	B2RQ86	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Mammalian Phenotype