Mycn (v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived) - Rat Genome Database

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Gene: Mycn (v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived) Mus musculus
Analyze
Symbol: Mycn
Name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
RGD ID: 1614446
MGI Page MGI
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and kinase binding activity. Involved in negative regulation of reactive oxygen species metabolic process and positive regulation of transcription by RNA polymerase II. Acts upstream of with a positive effect on autosome genomic imprinting. Acts upstream of or within several processes, including negative regulation of astrocyte differentiation; positive regulation of cell population proliferation; and skeletal system morphogenesis. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; lung; and sensory organ. Human ortholog(s) of this gene implicated in Feingold syndrome. Orthologous to human MYCN (MYCN proto-oncogene, bHLH transcription factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bHLHe3; bHLHe37; c-nmyc; N-my; N-myc; N-myc proto-oncogene protein; neuroblastoma myc-related oncogene 1; Nmy; Nmyc; Nmyc-; Nmyc-1; Nmyc1; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391212,986,094 - 12,991,837 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1212,986,094 - 12,991,915 (-)EnsemblGRCm39 Ensembl
GRCm381212,936,093 - 12,941,836 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1212,936,093 - 12,941,914 (-)EnsemblGRCm38mm10GRCm38
MGSCv371212,942,899 - 12,948,642 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361212,962,079 - 12,967,694 (-)NCBIMGSCv36mm8
Celera1213,282,496 - 13,288,240 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map126.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(R)-pantothenic acid  (ISO)
1,2-dichloroethane  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloroethene  (EXP)
chloroprene  (EXP)
choline  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
coumarin  (ISO)
crizotinib  (ISO)
crocin-1  (ISO)
Cuprizon  (ISO)
deoxynivalenol  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (EXP)
dichloroacetic acid  (EXP)
dichromium trioxide  (ISO)
dieldrin  (ISO)
diethyl maleate  (EXP)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
emetine  (ISO)
entinostat  (ISO)
ethanol  (EXP)
etoposide  (ISO)
fenvalerate  (ISO)
folic acid  (EXP)
fonofos  (ISO)
furan  (ISO)
genistein  (EXP,ISO)
glyphosate  (EXP)
Heptachlor epoxide  (EXP)
hydrogen cyanide  (EXP)
isoprenaline  (EXP)
isotretinoin  (ISO)
ketamine  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
leflunomide  (EXP)
LY294002  (ISO)
maneb  (EXP)
methapyrilene  (ISO)
methimazole  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-nitrosodiethylamine  (EXP)
nickel dichloride  (ISO)
niclosamide  (ISO)
ozone  (EXP)
p-menthan-3-ol  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
paraquat  (EXP,ISO)
parathion  (ISO)
PCB138  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
permethrin  (ISO)
phenobarbital  (EXP)
potassium cyanide  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP,ISO)
retinyl acetate  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sonidegib  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
terbufos  (ISO)
testosterone  (ISO)
Testosterone propionate  (EXP)
thapsigargin  (ISO)
titanium dioxide  (EXP)
Tributyltin oxide  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
Tryptanthrine  (ISO)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vincristine  (ISO)
vismodegib  (ISO)
vorinostat  (ISO)
wortmannin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IDA,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal angiogenesis  (IAGP)
abnormal anterior cardinal vein morphology  (IAGP)
abnormal apical ectodermal ridge morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal branching involved in lung morphogenesis  (IAGP)
abnormal cardiac epithelial to mesenchymal transition  (IAGP)
abnormal cerebellar foliation  (IAGP)
abnormal cerebellar granule layer morphology  (IAGP)
abnormal cerebellar molecular layer  (IAGP)
abnormal cerebellar Purkinje cell layer  (IAGP)
abnormal cerebellum development  (IAGP)
abnormal cerebellum external granule cell layer morphology  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal cortical ventricular zone morphology  (IAGP)
abnormal cranial ganglia morphology  (IAGP)
abnormal dorsal aorta morphology  (IAGP)
abnormal embryo development  (IAGP)
abnormal embryonic neuroepithelial layer differentiation  (IAGP)
abnormal embryonic neuroepithelium morphology  (IAGP)
abnormal fetal cardiomyocyte proliferation  (IAGP)
abnormal forebrain development  (IAGP)
abnormal heart development  (IAGP)
abnormal intestinal epithelium morphology  (IAGP)
abnormal large intestine morphology  (IAGP)
abnormal lens vesicle development  (IAGP)
abnormal limb bud morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal liver development  (IAGP)
abnormal liver morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung epithelium morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal medulla oblongata morphology  (IAGP)
abnormal mesonephric mesenchyme morphology  (IAGP)
abnormal mesonephros morphology  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal neuronal precursor proliferation  (IAGP)
abnormal optic vesicle formation  (IAGP)
abnormal pulmonary alveolus epithelial cell morphology  (IAGP)
abnormal stomach morphology  (IAGP)
abnormal vein morphology  (IAGP)
abnormal vertebrae morphology  (IAGP)
abnormal vertebral body development  (IAGP)
abnormal Wolffian duct morphology  (IAGP)
absent stomach  (IAGP)
absent vitelline blood vessels  (IAGP)
anemia  (IAGP)
common ventricle  (IAGP)
congestive heart failure  (IAGP)
decreased body length  (IAGP)
decreased brain size  (IAGP)
decreased brain weight  (IAGP)
decreased cerebellar granule cell number  (IAGP)
decreased embryo size  (IAGP)
decreased embryonic neuroepithelium thickness  (IAGP)
decreased fetal size  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased neuronal precursor cell number  (IAGP)
decreased Purkinje cell number  (IAGP)
decreased survivor rate  (IAGP)
decreased type I pneumocyte number  (IAGP)
decreased type II pneumocyte number  (IAGP)
dilated dorsal aorta  (IAGP)
disorganized dorsal root ganglion  (IAGP)
dorsal root ganglion hypoplasia  (IAGP)
ectopic Purkinje cell  (IAGP)
edema  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
first pharyngeal arch hypoplasia  (IAGP)
gonadal ridge hypoplasia  (IAGP)
hemorrhage  (IAGP)
impaired branching involved in bronchus morphogenesis  (IAGP)
increased hepatocyte apoptosis  (IAGP)
kinked tail  (IAGP)
liver hypoplasia  (IAGP)
microcephaly  (IAGP)
microphthalmia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
no spontaneous movement  (IAGP)
pale yolk sac  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature neuronal precursor differentiation  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
pulmonary hypoplasia  (IAGP)
respiratory distress  (IAGP)
respiratory failure  (IAGP)
small cerebellum  (IAGP)
small dorsal root ganglion  (IAGP)
small heart  (IAGP)
small kidney  (IAGP)
small liver  (IAGP)
small trigeminal ganglion  (IAGP)
small vertebral body  (IAGP)
syndactyly  (IAGP)
telencephalon hypoplasia  (IAGP)
thin myocardium  (IAGP)
thin myocardium compact layer  (IAGP)
trabecula carnea hypoplasia  (IAGP)
vertebral fusion  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1409609   PMID:1459449   PMID:1459450   PMID:1577267   PMID:1644290   PMID:1701023   PMID:1769649   PMID:1794058   PMID:1922066   PMID:1931830   PMID:2031852   PMID:2120050  
PMID:2470008   PMID:2501083   PMID:2555695   PMID:2577870   PMID:2653809   PMID:2654812   PMID:2663644   PMID:3015591   PMID:3049618   PMID:3197454   PMID:3287334   PMID:3513190  
PMID:3840574   PMID:3860871   PMID:7529553   PMID:7655079   PMID:7733512   PMID:7789282   PMID:7789972   PMID:7873892   PMID:7882978   PMID:7887448   PMID:7990960   PMID:8095010  
PMID:8098844   PMID:8150745   PMID:8287798   PMID:8404543   PMID:8521822   PMID:8617250   PMID:8657155   PMID:9000049   PMID:9110315   PMID:9441679   PMID:9519870   PMID:9520320  
PMID:9635194   PMID:9798678   PMID:9856457   PMID:10021345   PMID:10229200   PMID:10349636   PMID:10381566   PMID:10433800   PMID:10506756   PMID:10573140   PMID:10581191   PMID:10837121  
PMID:10892744   PMID:10944220   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11420610   PMID:11687289   PMID:11742404   PMID:11756639   PMID:12381668   PMID:12441288   PMID:12466851  
PMID:12477932   PMID:12502747   PMID:12777630   PMID:12904583   PMID:12905154   PMID:14610273   PMID:14624490   PMID:14660435   PMID:15028671   PMID:15136151   PMID:15226823   PMID:15342473  
PMID:15342483   PMID:15361625   PMID:15464586   PMID:15618518   PMID:15716345   PMID:15797020   PMID:15843407   PMID:15907834   PMID:15953367   PMID:16054035   PMID:16133151   PMID:16141072  
PMID:16141073   PMID:16325481   PMID:16396903   PMID:16414041   PMID:16543498   PMID:16602821   PMID:16724113   PMID:16864777   PMID:16901790   PMID:16912192   PMID:16951180   PMID:17097888  
PMID:17222338   PMID:17332425   PMID:17357786   PMID:17360777   PMID:17428829   PMID:17486137   PMID:17585069   PMID:17699607   PMID:17765889   PMID:17951258   PMID:17998397   PMID:18006809  
PMID:18198336   PMID:18287559   PMID:18324732   PMID:18356167   PMID:18367557   PMID:18488021   PMID:18533146   PMID:18536717   PMID:18550708   PMID:18550710   PMID:18557763   PMID:18607644  
PMID:18640244   PMID:18776145   PMID:19022256   PMID:19041778   PMID:19171780   PMID:19208763   PMID:19234491   PMID:19287388   PMID:19463158   PMID:19574443   PMID:19649205   PMID:19686682  
PMID:19686689   PMID:19796622   PMID:19966223   PMID:20059953   PMID:20211142   PMID:20215343   PMID:20412781   PMID:20478998   PMID:20506362   PMID:20530674   PMID:20537458   PMID:20660756  
PMID:20804970   PMID:20855530   PMID:21047779   PMID:21068393   PMID:21129374   PMID:21267068   PMID:21297076   PMID:21307096   PMID:21349854   PMID:21385574   PMID:21440680   PMID:21448975  
PMID:21494559   PMID:21562282   PMID:21623382   PMID:21646478   PMID:21677750   PMID:21698133   PMID:21750028   PMID:21779394   PMID:21873635   PMID:22164278   PMID:22184065   PMID:22218692  
PMID:22412967   PMID:22420299   PMID:22438573   PMID:22465667   PMID:22624711   PMID:22745758   PMID:22751132   PMID:22789543   PMID:22833126   PMID:22879379   PMID:22907436   PMID:22921766  
PMID:23022312   PMID:23041177   PMID:23063798   PMID:23193000   PMID:23223288   PMID:23314057   PMID:23342106   PMID:23483698   PMID:23554972   PMID:23639551   PMID:23665319   PMID:23674600  
PMID:23924632   PMID:24146773   PMID:24154525   PMID:24184637   PMID:24191021   PMID:24293546   PMID:24376126   PMID:24397388   PMID:24608896   PMID:24661562   PMID:24946904   PMID:24952961  
PMID:24982181   PMID:25150496   PMID:25171250   PMID:25182747   PMID:25196150   PMID:25437558   PMID:25458011   PMID:25516969   PMID:25557119   PMID:25785590   PMID:25848000   PMID:25848055  
PMID:25912685   PMID:25973900   PMID:26081154   PMID:26139524   PMID:26160903   PMID:26222553   PMID:26238256   PMID:26829053   PMID:26833183   PMID:26871632   PMID:26876178   PMID:27166947  
PMID:27539729   PMID:27618649   PMID:27668798   PMID:27705805   PMID:27728805   PMID:27770432   PMID:27773673   PMID:28007786   PMID:28165337   PMID:28459463   PMID:28705898   PMID:28711493  
PMID:28716713   PMID:28807939   PMID:28923932   PMID:28993399   PMID:29031500   PMID:29184203   PMID:29371594   PMID:29386106   PMID:29444209   PMID:29445162   PMID:29540665   PMID:29636449  
PMID:29743679   PMID:30054041   PMID:30061166   PMID:30182136   PMID:30250269   PMID:30389914   PMID:30521142   PMID:30566624   PMID:30573562   PMID:30642836   PMID:30670683   PMID:30879743  
PMID:31042497   PMID:31092920   PMID:31118412   PMID:31776260   PMID:32325033   PMID:32595833   PMID:32820040   PMID:33387268   PMID:33410138   PMID:33591268   PMID:33804256   PMID:34289374  
PMID:34321999   PMID:34431536   PMID:34506481   PMID:34590686   PMID:34710087   PMID:34716243   PMID:34915728   PMID:34921112   PMID:35193672   PMID:35322202   PMID:35942939   PMID:35951005  
PMID:36661413   PMID:36734327   PMID:36960826   PMID:38297207   PMID:38336749  


Genomics

Comparative Map Data
Mycn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391212,986,094 - 12,991,837 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1212,986,094 - 12,991,915 (-)EnsemblGRCm39 Ensembl
GRCm381212,936,093 - 12,941,836 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1212,936,093 - 12,941,914 (-)EnsemblGRCm38mm10GRCm38
MGSCv371212,942,899 - 12,948,642 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361212,962,079 - 12,967,694 (-)NCBIMGSCv36mm8
Celera1213,282,496 - 13,288,240 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map126.14NCBI
MYCN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38215,940,550 - 15,947,004 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl215,940,550 - 15,947,007 (+)EnsemblGRCh38hg38GRCh38
GRCh37216,080,672 - 16,087,126 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36215,998,134 - 16,004,580 (+)NCBINCBI36Build 36hg18NCBI36
Build 34216,032,643 - 16,037,721NCBI
Celera215,998,381 - 16,004,827 (+)NCBICelera
Cytogenetic Map2p24.3NCBI
HuRef215,934,021 - 15,938,396 (+)NCBIHuRef
CHM1_1216,010,469 - 16,016,915 (+)NCBICHM1_1
T2T-CHM13v2.0215,972,182 - 15,978,635 (+)NCBIT2T-CHM13v2.0
Mycn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8641,446,683 - 41,452,584 (-)NCBIGRCr8
mRatBN7.2635,717,764 - 35,723,590 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl635,717,764 - 35,723,590 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx636,030,195 - 36,036,011 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0636,344,835 - 36,350,651 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0635,812,708 - 35,818,534 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0638,222,554 - 38,228,419 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl638,222,555 - 38,228,379 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0651,348,169 - 51,354,719 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4636,508,262 - 36,514,071 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera635,082,308 - 35,088,132 (-)NCBICelera
Cytogenetic Map6q15NCBI
Mycn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554879,219,528 - 9,224,818 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554879,219,528 - 9,224,818 (+)NCBIChiLan1.0ChiLan1.0
MYCN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212110,580,807 - 110,585,956 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A110,584,779 - 110,591,313 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A15,925,130 - 15,931,605 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A16,058,298 - 16,064,547 (+)NCBIpanpan1.1PanPan1.1panPan2
MYCN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11711,720,857 - 11,724,308 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1711,663,228 - 11,669,338 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01711,848,344 - 11,854,451 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1711,848,002 - 11,854,448 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11711,707,661 - 11,713,769 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01711,718,338 - 11,724,418 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01711,742,671 - 11,748,783 (+)NCBIUU_Cfam_GSD_1.0
Mycn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629256,215,359 - 56,221,421 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649314,618,060 - 14,624,315 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649314,618,176 - 14,624,201 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYCN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3121,543,109 - 121,549,046 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13121,543,201 - 121,549,678 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23129,821,890 - 129,827,921 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYCN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11491,685,376 - 91,692,091 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604520,532,406 - 20,539,075 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mycn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624865780,163 - 785,776 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mycn
206 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:829
Count of miRNA genes:322
Interacting mature miRNAs:410
Transcripts:ENSMUST00000043396, ENSMUST00000130990, ENSMUST00000151534
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301393Dyscalc3_mdystrophic cardiac calcinosis 3 (mouse)Not determined12122418579Mouse
12910983Pifs1_mpeptide-induced fatal syndrome 1 (mouse)12130433078Mouse
4141436Chldq7_mcholesterol and HDL QTL 7 (mouse)Not determined12127920733Mouse
1301655Bmd12_mbone mineral density 12 (mouse)Not determined12124662697Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133430339Mouse
1301143Skull17_mskull morphology 17 (mouse)Not determined12122418579Mouse
1301723Fcsa7_mfemoral cross-sectional area 7 (mouse)Not determined12949100443491112Mouse
11039525Tbbr2_mTrypanosoma brucei brucei response 2 (mouse)12122418579Mouse
4141296Femwf9_mfemur work to failure 9 (mouse)Not determined127920733Mouse
12792982Fbmd4_mfemoral bone mineral density 4, females only (mouse)121004319424365136Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
1357519Vtbt12_mvertebral trabecular bone trait 12 (mouse)Not determined12124662697Mouse
10402496Lmr22_mleishmaniasis resistance 22 (mouse)Not determined12122418579Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
26884410Bzwq15_mbi-zygomatic width QTL 15, 16 week (mouse)12365000029749999Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1234013434340302Mouse
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
13524843Ppiq8_mprepulse inhibition QTL 8 (mouse)121104319450945796Mouse
13208568Bmiq11_mbody mass index QTL 11 (mouse)12805000040049999Mouse
4141516slwr_mslowlearner (mouse)Not determined1239247546392614Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132758756Mouse
1301163Eae16_msusceptibility to experimental allergic encephalomyelitis 16 (mouse)Not determined12772315841723301Mouse
14746972Manh72_mmandible shape 72 (mouse)121061528144615281Mouse
1301037Cd4ts5_mCD4 T cell subset 5 (mouse)Not determined12835244442352581Mouse
10401249Bglu15_mblood glucose level 15 (mouse)Not determined121062064244620809Mouse

Markers in Region
UniSTS:225296  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381212,936,608 - 12,936,800UniSTSGRCm38
MGSCv371212,943,414 - 12,943,606UniSTSGRCm37
Celera1213,283,011 - 13,283,203UniSTS
Cytogenetic Map12A3-BUniSTS
Mycn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381212,936,143 - 12,936,853UniSTSGRCm38
MGSCv371212,942,949 - 12,943,659UniSTSGRCm37
Celera1213,282,546 - 13,283,256UniSTS
Cytogenetic Map12A3-BUniSTS
Nmyc1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381212,941,995 - 12,942,187UniSTSGRCm38
MGSCv371212,948,801 - 12,948,993UniSTSGRCm37
Celera1213,288,399 - 13,288,584UniSTS
Cytogenetic Map12A3-BUniSTS
cM Map124.0UniSTS
Nmyc1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381212,936,611 - 12,937,015UniSTSGRCm38
MGSCv371212,943,417 - 12,943,821UniSTSGRCm37
Celera1213,283,014 - 13,283,417UniSTS
Cytogenetic Map12A3-BUniSTS
cM Map124.0UniSTS
Mycn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381212,937,308 - 12,937,527UniSTSGRCm38
MGSCv371212,944,114 - 12,944,333UniSTSGRCm37
Celera1213,283,710 - 13,283,929UniSTS
Cytogenetic Map12A3-BUniSTS
MYCN  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381212,941,381 - 12,941,833UniSTSGRCm38
MGSCv371212,948,187 - 12,948,639UniSTSGRCm37
Celera1213,287,787 - 13,288,237UniSTS
Cytogenetic Map12A3-BUniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000043396   ⟹   ENSMUSP00000045993
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1212,986,094 - 12,991,915 (-)Ensembl
GRCm38.p6 Ensembl1212,936,093 - 12,941,914 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130990   ⟹   ENSMUSP00000114225
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1212,986,097 - 12,990,617 (-)Ensembl
GRCm38.p6 Ensembl1212,936,096 - 12,940,616 (-)Ensembl
Ensembl Acc Id: ENSMUST00000151534
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1212,990,945 - 12,991,826 (-)Ensembl
GRCm38.p6 Ensembl1212,940,944 - 12,941,825 (-)Ensembl
RefSeq Acc Id: NM_008709   ⟹   NP_032735
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391212,986,094 - 12,991,837 (-)NCBI
GRCm381212,936,093 - 12,941,836 (-)ENTREZGENE
MGSCv371212,942,899 - 12,948,642 (-)RGD
Celera1213,282,496 - 13,288,240 (-)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032735   ⟸   NM_008709
- UniProtKB: Q61978 (UniProtKB/Swiss-Prot),   P03966 (UniProtKB/Swiss-Prot),   Q3UII1 (UniProtKB/TrEMBL),   Q923F4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000114225   ⟸   ENSMUST00000130990
Ensembl Acc Id: ENSMUSP00000045993   ⟸   ENSMUST00000043396
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P03966-F1-model_v2 AlphaFold P03966 1-462 view protein structure

Promoters
RGD ID:8677928
Promoter ID:EPDNEW_M16995
Type:multiple initiation site
Name:Mycn_1
Description:Mus musculus v-myc avian myelocytomatosis viral related oncogene,neuroblastoma derived , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381212,941,836 - 12,941,896EPDNEW
RGD ID:6823213
Promoter ID:MM_KWN:11175
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:UC007NBF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361212,947,181 - 12,947,681 (-)MPROMDB
RGD ID:6823212
Promoter ID:MM_KWN:11176
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Lung
Transcripts:OTTMUST00000081205,   OTTMUST00000081207
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361212,948,486 - 12,949,577 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97357 AgrOrtholog
Ensembl Genes ENSMUSG00000037169 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000043396 ENTREZGENE
  ENSMUST00000043396.15 UniProtKB/Swiss-Prot
  ENSMUST00000130990.2 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myc_transcription_factors UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tscrpt_reg_Myc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tscrpt_reg_Myc_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97357 ENTREZGENE
NCBI Gene 18109 ENTREZGENE
PANTHER MYC PROTO-ONCOGENE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  N-MYC PROTO-ONCOGENE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myc_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mycn PhenoGen
PIRSF Myc_protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS LEUZIPPRMYC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt MYCN_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UII1 ENTREZGENE, UniProtKB/TrEMBL
  Q61978 ENTREZGENE
  Q810L7_MOUSE UniProtKB/TrEMBL
  Q923F4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q61978 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Mycn  v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived    v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)  Symbol and/or name change 5135510 APPROVED