Or4d10b (olfactory receptor family 4 subfamily D member 10B) - Rat Genome Database

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Gene: Or4d10b (olfactory receptor family 4 subfamily D member 10B) Mus musculus
Analyze
Symbol: Or4d10b
Name: olfactory receptor family 4 subfamily D member 10B
RGD ID: 1614101
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR4D10 (olfactory receptor family 4 subfamily D member 10).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2RE5P-2418550-2417609; MOR239; MOR239-2; olfactory receptor 1424; olfactory receptor MOR239-2; Olfr1424
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391912,036,173 - 12,037,114 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1912,035,988 - 12,040,046 (-)EnsemblGRCm39 Ensembl
GRCm381912,058,809 - 12,059,750 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1912,058,624 - 12,062,682 (-)EnsemblGRCm38mm10GRCm38
MGSCv371912,133,299 - 12,134,240 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361912,125,854 - 12,126,795 (-)NCBIMGSCv36mm8
Celera1912,756,191 - 12,757,132 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map198.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:14611657   PMID:21873635   PMID:32295537  


Genomics

Comparative Map Data
Or4d10b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391912,036,173 - 12,037,114 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1912,035,988 - 12,040,046 (-)EnsemblGRCm39 Ensembl
GRCm381912,058,809 - 12,059,750 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1912,058,624 - 12,062,682 (-)EnsemblGRCm38mm10GRCm38
MGSCv371912,133,299 - 12,134,240 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361912,125,854 - 12,126,795 (-)NCBIMGSCv36mm8
Celera1912,756,191 - 12,757,132 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map198.58NCBI
OR4D10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381159,473,315 - 59,479,361 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1159,473,315 - 59,479,361 (+)EnsemblGRCh38hg38GRCh38
GRCh371159,240,788 - 59,246,834 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,001,479 - 59,002,414 (+)NCBINCBI36Build 36hg18NCBI36
Build 341159,001,478 - 59,002,414NCBI
Celera1156,606,185 - 56,607,120 (+)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1155,592,733 - 55,593,668 (+)NCBIHuRef
CHM1_11159,110,678 - 59,111,613 (+)NCBICHM1_1
T2T-CHM13v2.01159,424,187 - 59,430,238 (+)NCBIT2T-CHM13v2.0
Or4d10c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81218,441,392 - 218,442,327 (-)NCBIGRCr8
mRatBN7.21209,016,663 - 209,017,598 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1209,015,124 - 209,020,125 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1217,391,321 - 217,392,256 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01224,367,473 - 224,368,408 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,145,756 - 217,146,691 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01228,523,504 - 228,524,439 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1228,523,504 - 228,524,439 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01235,587,344 - 235,588,279 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41214,940,573 - 214,941,508 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11215,099,002 - 215,099,938 (-)NCBI
Celera1206,482,817 - 206,483,752 (-)NCBICelera
Cytogenetic Map1q43NCBI
LOC100974724
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2960,611,350 - 60,612,288 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11161,654,471 - 61,655,406 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01154,705,497 - 54,706,508 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11158,157,201 - 58,158,212 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1158,157,252 - 58,158,187 (+)Ensemblpanpan1.1panPan2
OR4D9C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11837,249,661 - 37,250,596 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1837,249,661 - 37,250,596 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1836,899,044 - 36,899,979 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01837,890,200 - 37,891,135 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1837,890,200 - 37,891,135 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11837,479,712 - 37,480,647 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01837,055,850 - 37,056,785 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01837,685,536 - 37,686,471 (-)NCBIUU_Cfam_GSD_1.0
LOC100522475
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl211,972,196 - 11,973,130 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1211,972,196 - 11,973,130 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2211,446,298 - 11,447,233 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103234902
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1114,114,798 - 14,117,607 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl114,116,041 - 14,116,958 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038111,437,966 - 111,438,971 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Or4d10b
24 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:61
Interacting mature miRNAs:61
Transcripts:ENSMUST00000087830
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122371338Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120695286Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19332855120539663Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19978745343787602Mouse
14928311Manh85_mmandible shape 85 (mouse)191191478945914789Mouse
38455997Cdtm2_mCD62L+ CD8 TM cells 2 (mouse)19997736419977364Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120328703Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19930571543305821Mouse

Markers in Region
UniSTS:495352  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381912,058,730 - 12,059,806UniSTSGRCm38
MGSCv371912,133,220 - 12,134,296UniSTSGRCm37
Celera1912,756,112 - 12,757,187UniSTS
Cytogenetic Map19C1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000087830   ⟹   ENSMUSP00000085132
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1912,036,173 - 12,037,114 (-)Ensembl
GRCm38.p6 Ensembl1912,058,809 - 12,059,750 (-)Ensembl
Ensembl Acc Id: ENSMUST00000207681   ⟹   ENSMUSP00000146552
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1912,035,988 - 12,040,046 (-)Ensembl
GRCm38.p6 Ensembl1912,058,624 - 12,062,682 (-)Ensembl
RefSeq Acc Id: NM_146681   ⟹   NP_666892
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391912,036,173 - 12,037,114 (-)NCBI
GRCm381912,058,809 - 12,059,750 (-)ENTREZGENE
MGSCv371912,133,299 - 12,134,240 (-)RGD
Celera1912,756,191 - 12,757,132 (-)RGD
cM Map19 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_666892 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL61077 (Get FASTA)   NCBI Sequence Viewer  
  AAP71800 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000085132
  ENSMUSP00000085132.2
  ENSMUSP00000146552.3
RefSeq Acc Id: NP_666892   ⟸   NM_146681
- UniProtKB: Q8VFV1 (UniProtKB/TrEMBL),   F7CNV2 (UniProtKB/TrEMBL),   K7N659 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000085132   ⟸   ENSMUST00000087830
Ensembl Acc Id: ENSMUSP00000146552   ⟸   ENSMUST00000207681
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VFV1-F1-model_v2 AlphaFold Q8VFV1 1-313 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3031258 AgrOrtholog
Ensembl Genes ENSMUSG00000067528 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000087830 ENTREZGENE
  ENSMUST00000087830.2 UniProtKB/TrEMBL
  ENSMUST00000207681.4 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
KEGG Report mmu:258676 UniProtKB/TrEMBL
MGD MGI:3031258 ENTREZGENE
NCBI Gene 258676 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 4D10 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or4d10b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt F7CNV2 ENTREZGENE
  K7N659 ENTREZGENE
  Q8VFV1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F7CNV2 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or4d10b  olfactory receptor family 4 subfamily D member 10B  Olfr1424  olfactory receptor 1424  Symbol and/or name change 5135510 APPROVED