Mir155 (microRNA 155) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Mir155 (microRNA 155) Mus musculus
Analyze
Symbol: Mir155
Name: microRNA 155
RGD ID: 1608318
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular response to cytokine stimulus; cellular response to dexamethasone stimulus; and regulation of gene expression. Is expressed in cumulus of mature follicle; early conceptus; and oocyte. Used to study lymphoma. Human ortholog(s) of this gene implicated in colon adenocarcinoma; hepatocellular carcinoma; oropharynx cancer; and type 1 diabetes mellitus. Orthologous to human MIR155 (microRNA 155).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-155; Mirn; Mirn155; mmu-mir-1; mmu-mir-155
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391684,511,028 - 84,511,092 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1684,511,028 - 84,511,092 (+)EnsemblGRCm39 Ensembl
GRCm381684,714,140 - 84,714,204 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1684,714,140 - 84,714,204 (+)EnsemblGRCm38mm10GRCm38
MGSCv371684,714,385 - 84,714,449 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1684,918,138 - 84,918,202 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1646.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (IEP,IMP)
Acute Lung Injury  (IEP,IMP)
acute myeloid leukemia  (ISO)
acute myocardial infarction  (ISO)
acute pancreatitis  (ISO)
adult respiratory distress syndrome  (ISO)
Albuminuria  (ISO)
alcoholic hepatitis  (IMP,ISO)
Alcoholic Liver Diseases  (IEP,IMP,ISO)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (ISO)
Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy  (ISO)
Angina Pectoris  (ISO)
Arsenic Poisoning  (ISO)
atherosclerosis  (IEP,IMP,ISO)
atrophic gastritis  (ISO)
autoimmune hepatitis  (IMP,ISO)
Behcet's disease  (ISO)
biliary atresia  (IEP,ISO)
Carcinoid Tumor  (ISO)
Chemical and Drug Induced Liver Injury  (IDA,IMP)
cholangiocarcinoma  (ISO)
cholera  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Hepatitis C  (ISO)
chronic lymphocytic leukemia  (ISO)
Chronic Periodontitis  (ISO)
colon adenocarcinoma  (ISO)
colon cancer  (IMP,ISO)
Colonic Polyps  (IMP)
colorectal cancer  (ISO)
coronary artery disease  (ISO)
Crohn's disease  (ISO)
cystic fibrosis  (ISO)
Down syndrome  (ISO)
encephalomyelitis  (IMP)
Endotoxemia  (IEP)
Endotoxin Hyporesponsiveness  (IMP)
esophageal cancer  (ISO)
Experimental Colitis  (IEP,IMP,ISO)
Experimental Mammary Neoplasms  (ISO)
familial adenomatous polyposis  (ISO)
Fibrosis  (IMP)
Flaviviridae Infections  (ISO)
gallbladder carcinoma  (ISO)
gastritis  (ISO)
head and neck squamous cell carcinoma  (ISO)
Helicobacter Infections  (IEP,ISO)
hepatitis B  (ISO)
hepatocellular carcinoma  (ISO)
hyperglycemia  (IMP)
Insulin Resistance  (IMP,ISO)
Intervertebral Disc Disease  (IDA,ISO)
Intestinal Reperfusion Injury  (IEP)
liposarcoma  (ISO)
liver cirrhosis  (ISO)
Liver Injury  (IMP)
Liver Metastasis  (ISO)
Liver Reperfusion Injury  (IMP)
Lung Neoplasms  (ISO)
Lymphatic Metastasis  (ISO)
lymphoma  (IAGP)
metabolic dysfunction and alcohol associated liver disease  (IMP)
metabolic dysfunction-associated steatotic liver disease  (IMP,ISO)
Microsatellite Instability  (ISO)
multiple myeloma  (ISO)
myocardial infarction  (IMP)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
Neurodevelopmental Disorders  (ISO)
obesity  (IMP,ISO)
Oral Lichen Planus  (ISO)
oral squamous cell carcinoma  (ISO)
oropharynx cancer  (ISO)
pancreatic carcinoma  (ISO)
pancreatic ductal adenocarcinoma  (ISO)
pancreatitis  (ISO)
Parkinson's disease  (ISO)
Pediatric Crohn's Disease  (ISO)
peritonitis  (IEP,IMP)
pre-eclampsia  (ISO)
primary sclerosing cholangitis  (ISO)
prostate cancer  (ISO)
rheumatic heart disease  (ISO)
salivary gland adenoid cystic carcinoma  (ISO)
Sepsis  (IEP,ISO)
Septic Peritonitis  (ISO)
severe pre-eclampsia  (ISO)
stomach cancer  (ISO)
tongue cancer  (ISO)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (ISO)
traumatic brain injury  (IMP)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
visceral leishmaniasis  (IMP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,5-hexanedione  (ISO)
2-acetamidofluorene  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
Bandrowski's base  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (ISO)
buta-1,3-diene  (EXP)
cadmium dichloride  (ISO)
cannabidiol  (EXP)
carbamazepine  (ISO)
carbon atom  (ISO)
carboplatin  (ISO)
chloroquine  (ISO)
choline  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
clopidogrel  (ISO)
cypermethrin  (EXP)
Deoxycorticosterone acetate  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (EXP,ISO)
doxorubicin  (ISO)
elemental carbon  (ISO)
fluoranthene  (EXP)
folic acid  (EXP)
fumonisin B1  (ISO)
galaxolide  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
isoprenaline  (ISO)
isorhamnetin  (EXP)
L-methionine  (EXP)
lamotrigine  (ISO)
lipopolysaccharide  (EXP)
lithium chloride  (ISO)
mechlorethamine  (EXP)
metformin  (ISO)
methamidophos  (ISO)
methanol  (EXP)
morphine  (ISO)
Octicizer  (EXP)
ozone  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
piperacillin  (ISO)
poly(I:C)  (EXP)
progesterone  (EXP,ISO)
propofol  (ISO)
puromycin  (ISO)
quercetin  (EXP)
resveratrol  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
Sinomenine  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
streptozocin  (EXP)
sulfamethoxazole  (ISO)
sulfur dioxide  (ISO)
T-2 toxin  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
trichostatin A  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell physiology  (IAGP)
abnormal bronchiole morphology  (IAGP)
abnormal CD4-positive, alpha beta T cell morphology  (IAGP)
abnormal CD4-positive, alpha-beta T cell physiology  (IAGP)
abnormal class switch recombination  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal dendritic cell physiology  (IAGP)
abnormal germinal center B cell physiology  (IAGP)
abnormal gut-associated lymphoid tissue morphology  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal immune system morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal Peyer's patch germinal center morphology  (IAGP)
abnormal T cell physiology  (IAGP)
abnormal T-helper 1 cell morphology  (IAGP)
abnormal T-helper 17 cell differentiation  (IAGP)
chromosomal instability  (IAGP)
decreased effector memory T-helper cell number  (IAGP)
decreased germinal center B cell number  (IAGP)
decreased IgG1 level  (IAGP)
decreased IgM level  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased interleukin-4 secretion  (IAGP)
decreased interleukin-6 secretion  (IAGP)
decreased regulatory T cell number  (IAGP)
decreased spleen germinal center number  (IAGP)
decreased spleen germinal center size  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased T-helper 17 cell number  (IAGP)
decreased tumor necrosis factor secretion  (IAGP)
increased interleukin-10 secretion  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased T-helper 2 cell number  (IAGP)
intestinal inflammation  (IAGP)
lung inflammation  (IAGP)
no abnormal phenotype detected  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Evaluation of the miRNA-146a and miRNA-155 Expression Levels in Patients with Oral Lichen Planus. Ahmadi-Motamayel F, etal., Iran J Immunol. 2017 Dec;14(4):316-324. doi: IJIv14i4A6.
2. Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli. Alexander M, etal., J Immunol. 2017 Nov 15;199(10):3559-3570. doi: 10.4049/jimmunol.1700904. Epub 2017 Oct 4.
3. Long non-coding RNA CCAT1 is overexpressed in oral squamous cell carcinomas and predicts poor prognosis. Arunkumar G, etal., Biomed Rep. 2017 Apr;6(4):455-462. doi: 10.3892/br.2017.876. Epub 2017 Mar 17.
4. Polymorphisms in genes encoding miR-155 and miR-146a are associated with protection to type 1 diabetes mellitus. Assmann TS, etal., Acta Diabetol. 2017 May;54(5):433-441. doi: 10.1007/s00592-016-0961-y. Epub 2017 Jan 19.
5. Dysregulated Autophagy and Lysosome Function Are Linked to Exosome Production by Micro-RNA 155 in Alcoholic Liver Disease. Babuta M, etal., Hepatology. 2019 Dec;70(6):2123-2141. doi: 10.1002/hep.30766. Epub 2019 Jun 24.
6. The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis. Bala S, etal., J Hepatol. 2016 Jun;64(6):1378-87. doi: 10.1016/j.jhep.2016.01.035. Epub 2016 Feb 8.
7. MicroRNA-155, -185 and -193b as biomarkers in human papillomavirus positive and negative tonsillar and base of tongue squamous cell carcinoma. Bersani C, etal., Oral Oncol. 2018 Jul;82:8-16. doi: 10.1016/j.oraloncology.2018.04.021. Epub 2018 May 4.
8. MicroRNA-155 potentiates the inflammatory response in hypothermia by suppressing IL-10 production. Billeter AT, etal., FASEB J. 2014 Dec;28(12):5322-36. doi: 10.1096/fj.14-258335. Epub 2014 Sep 17.
9. Induction of immunomodulatory miR-146a and miR-155 in small intestinal epithelium of Vibrio cholerae infected patients at acute stage of cholera. Bitar A, etal., PLoS One. 2017 Mar 20;12(3):e0173817. doi: 10.1371/journal.pone.0173817. eCollection 2017.
10. Expression of microRNA-155 in inflammatory cells modulates liver injury. Blaya D, etal., Hepatology. 2018 Aug;68(2):691-706. doi: 10.1002/hep.29833. Epub 2018 May 2.
11. Up-regulated expression of miR-155 in human colonic cancer. Cao H, etal., J Cancer Res Ther. 2018 Apr-Jun;14(3):604-607. doi: 10.4103/0973-1482.175432.
12. MiR-155 controls follicular Treg cell-mediated humoral autoimmune intestinal injury by inhibiting CTLA-4 expression. Chao G, etal., Int Immunopharmacol. 2019 Jun;71:267-276. doi: 10.1016/j.intimp.2019.03.009. Epub 2019 Mar 28.
13. Inhibition of miR‑155‑5p attenuates the valvular damage induced by rheumatic heart disease. Chen A, etal., Int J Mol Med. 2020 Feb;45(2):429-440. doi: 10.3892/ijmm.2019.4420. Epub 2019 Dec 6.
14. NF-kB-regulated exosomal miR-155 promotes the inflammation associated with arsenite carcinogenesis. Chen C, etal., Cancer Lett. 2017 Mar 1;388:21-33. doi: 10.1016/j.canlet.2016.11.027. Epub 2016 Nov 30.
15. Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia. Chen L, etal., Mol Cells. 2016 Apr 30;39(4):330-6. doi: 10.14348/molcells.2016.2308. Epub 2016 Feb 26.
16. Overexpression of IL-9 induced by STAT3 phosphorylation is mediated by miR-155 and miR-21 in chronic lymphocytic leukemia. Chen N, etal., Oncol Rep. 2018 Jun;39(6):3064-3072. doi: 10.3892/or.2018.6367. Epub 2018 Apr 12.
17. Differential Expression of MicroRNAs in Hepatitis C Virus-Mediated Liver Disease Between African Americans and Caucasians: Implications for Racial Health Disparities. Devhare PB, etal., Gene Expr. 2017 Feb 10;17(2):89-98. doi: 10.3727/105221616X693594. Epub 2016 Oct 19.
18. MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic disease. Dickey LL, etal., J Neuroinflammation. 2016 Sep 7;13(1):240. doi: 10.1186/s12974-016-0699-z.
19. Circulating microRNA-155 is associated with insulin resistance in chronic hepatitis C patients. El Samaloty NM, etal., Arab J Gastroenterol. 2019 Mar;20(1):1-7. doi: 10.1016/j.ajg.2019.01.011. Epub 2019 Mar 7.
20. Increased Levels of miR-155 are Related to Higher T-Cell Activation in the Peripheral Blood of Patients with Chronic Hepatitis B. Fang J, etal., Genet Test Mol Biomarkers. 2019 Feb;23(2):118-123. doi: 10.1089/gtmb.2018.0092.
21. MicroRNA Profiling and Target Genes Related to Metastasis of Salivary Adenoid Cystic Carcinoma. Feng X, etal., Anticancer Res. 2017 Jul;37(7):3473-3481. doi: 10.21873/anticanres.11715.
22. Deregulation of MicroRNAs in Gastric Lymphomagenesis Induced in the d3Tx Mouse Model of Helicobacter pylori Infection. Floch P, etal., Front Cell Infect Microbiol. 2017 May 16;7:185. doi: 10.3389/fcimb.2017.00185. eCollection 2017.
23. MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies. Gan L, etal., Medicine (Baltimore). 2017 Jul;96(28):e7515. doi: 10.1097/MD.0000000000007515.
24. MicroRNA-155 increases colon cancer chemoresistance to cisplatin by targeting forkhead box O3. Gao Y, etal., Oncol Lett. 2018 Apr;15(4):4781-4788. doi: 10.3892/ol.2018.7976. Epub 2018 Feb 7.
25. Early diagnostic role of PSA combined miR-155 detection in prostate cancer. Guo T, etal., Eur Rev Med Pharmacol Sci. 2018 Mar;22(6):1615-1621. doi: 10.26355/eurrev_201803_14568.
26. MicroRNA-31 and MicroRNA-155 Are Overexpressed in Ulcerative Colitis and Regulate IL-13 Signaling by Targeting Interleukin 13 Receptor α-1. Gwiggner M, etal., Genes (Basel). 2018 Feb 13;9(2). pii: genes9020085. doi: 10.3390/genes9020085.
27. Induction of miR-155 after Brain Injury Promotes Type 1 Interferon and has a Neuroprotective Effect. Harrison EB, etal., Front Mol Neurosci. 2017 Jul 28;10:228. doi: 10.3389/fnmol.2017.00228. eCollection 2017.
28. MiR-200b and miR-155 as predictive biomarkers for the efficacy of chemoradiation in locally advanced head and neck squamous cell carcinoma. Hess AK, etal., Eur J Cancer. 2017 May;77:3-12. doi: 10.1016/j.ejca.2017.02.018. Epub 2017 Mar 26.
29. Effect of microRNA-155 on the interferon-gamma signaling pathway in biliary atresia. Hsu YA, etal., Chin J Physiol. 2016 Dec 31;59(6):315-322. doi: 10.4077/CJP.2016.BAE419.
30. MicroRNA-155 inhibition attenuates endoplasmic reticulum stress-induced cardiomyocyte apoptosis following myocardial infarction via reducing macrophage inflammation. Hu J, etal., Eur J Pharmacol. 2019 Aug 15;857:172449. doi: 10.1016/j.ejphar.2019.172449. Epub 2019 Jun 14.
31. MiR-155 and its functional variant rs767649 contribute to the susceptibility and survival of hepatocellular carcinoma. Ji J, etal., Oncotarget. 2016 Sep 13;7(37):60303-60309. doi: 10.18632/oncotarget.11206.
32. MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene. Jiang S, etal., Cancer Res. 2010 Apr 15;70(8):3119-27. doi: 10.1158/0008-5472.CAN-09-4250. Epub 2010 Mar 30.
33. MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis. Jin HM, etal., Arthritis Res Ther. 2014 Apr 7;16(2):R88. doi: 10.1186/ar4531.
34. [In vivo imaging of breast tumors by a 99mTc radiolabeled probe targeting microRNA-155 in mice models]. Kang L, etal., Beijing Da Xue Xue Bao Yi Xue Ban. 2018 Apr 18;50(2):326-330.
35. Assessing the clinical value of microRNAs in formalin-fixed paraffin-embedded liposarcoma tissues: Overexpressed miR-155 is an indicator of poor prognosis. Kapodistrias N, etal., Oncotarget. 2017 Jan 24;8(4):6896-6913. doi: 10.18632/oncotarget.14320.
36. Potential Oncogenic Role and Prognostic Implication of MicroRNA-155-5p in Oral Squamous Cell Carcinoma. Kim H, etal., Anticancer Res. 2018 Sep;38(9):5193-5200. doi: 10.21873/anticanres.12842.
37. Determination of mir-155 and mir-146a expression rates and its association with expression level of TNF-α and CTLA4 genes in patients with Behcet's disease. Kolahi S, etal., Immunol Lett. 2018 Dec;204:55-59. doi: 10.1016/j.imlet.2018.10.012. Epub 2018 Oct 23.
38. Insights into epigenetic regulation of microRNA-155 expression in multiple myeloma. Krzeminski P, etal., Biochim Biophys Acta. 2015 Mar;1849(3):353-66. doi: 10.1016/j.bbagrm.2014.12.002. Epub 2014 Dec 11.
39. [Value of serum miR-155-5p and miR-133a-3p expression for the diagnosis and prognosis evaluation of sepsis]. Lan C, etal., Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2016 Aug;28(8):694-8. doi: 10.3760/cma.j.issn.2095-4352.2016.08.005.
40. The tumor suppressor role of miR-155-5p in gastric cancer. Li S, etal., Oncol Lett. 2018 Aug;16(2):2709-2714. doi: 10.3892/ol.2018.8932. Epub 2018 Jun 8.
41. Targeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy. Li Y, etal., Int J Nanomedicine. 2018 Mar 1;13:1241-1256. doi: 10.2147/IJN.S158290. eCollection 2018.
42. MicroRNA-155 Deficiency in Kupffer Cells Ameliorates Liver Ischemia-Reperfusion Injury in Mice. Li Y, etal., Transplantation. 2017 Jul;101(7):1600-1608. doi: 10.1097/TP.0000000000001765.
43. Rituximab May Cause Increased Hepatitis C Virus Viremia in Rheumatoid Arthritis Patients Through Declining Exosomal MicroRNA-155. Liao TL, etal., Arthritis Rheumatol. 2018 Aug;70(8):1209-1219. doi: 10.1002/art.40495. Epub 2018 Jun 27.
44. MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice. Lin X, etal., PLoS Genet. 2016 Oct 6;12(10):e1006308. doi: 10.1371/journal.pgen.1006308. eCollection 2016 Oct.
45. microRNA-155 Modulates Hepatic Stellate Cell Proliferation, Apoptosis, and Cell Cycle Progression in Rats With Alcoholic Hepatitis via the MAPK Signaling Pathway Through Targeting SOCS1. Liu D, etal., Front Pharmacol. 2020 Apr 7;11:270. doi: 10.3389/fphar.2020.00270. eCollection 2020.
46. MiR-155 Alleviates Septic Lung Injury by Inducing Autophagy Via Inhibition of Transforming Growth Factor-β-Activated Binding Protein 2. Liu F, etal., Shock. 2017 Jul;48(1):61-68. doi: 10.1097/SHK.0000000000000839.
47. The miR-124-p63 feedback loop modulates colorectal cancer growth. Liu K, etal., Oncotarget. 2017 Apr 25;8(17):29101-29115. doi: 10.18632/oncotarget.16248.
48. miR-155-5p is Negatively Associated with Acute Pancreatitis and Inversely Regulates Pancreatic Acinar Cell Progression by Targeting Rela and Traf3. Liu S, etal., Cell Physiol Biochem. 2018;51(4):1584-1599. doi: 10.1159/000495648. Epub 2018 Nov 29.
49. MiR-155 inhibition ameliorates 2, 4, 6-Trinitrobenzenesulfonic acid (TNBS)-induced experimental colitis in rat via influencing the differentiation of Th17 cells by Jarid2. Liu Y, etal., Int Immunopharmacol. 2018 Nov;64:401-410. doi: 10.1016/j.intimp.2018.09.007. Epub 2018 Sep 22.
50. Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma. Loosen SH, etal., PLoS One. 2019 Jan 17;14(1):e0210944. doi: 10.1371/journal.pone.0210944. eCollection 2019.
51. MicroRNA-155 promotes the pathogenesis of experimental colitis by repressing SHIP-1 expression. Lu ZJ, etal., World J Gastroenterol. 2017 Feb 14;23(6):976-985. doi: 10.3748/wjg.v23.i6.976.
52. MicroRNA-155 is upregulated in ascites in patients with spontaneous bacterial peritonitis. Lutz P, etal., Sci Rep. 2017 Jan 11;7:40556. doi: 10.1038/srep40556.
53. Anti-inflammatory effects of curcumin are associated with down regulating microRNA-155 in LPS-treated macrophages and mice. Ma F, etal., Pharm Biol. 2017 Dec;55(1):1263-1273. doi: 10.1080/13880209.2017.1297838.
54. Decreased Serum Level of miR-155 is Associated with Obesity and its Related Metabolic Traits. Mahdavi R, etal., Clin Lab. 2018 Jan 1;64(1):77-84. doi: 10.7754/Clin.Lab.2017.170618.
55. MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma. Mikamori M, etal., Sci Rep. 2017 Feb 15;7:42339. doi: 10.1038/srep42339.
56. miR-146a, miR-155, miR-370, and miR-708 Are CFTR-Dependent, Predicted FOXO1 Regulators and Change at Onset of CFRDs. Montanini L, etal., J Clin Endocrinol Metab. 2016 Dec;101(12):4955-4963. doi: 10.1210/jc.2016-2431. Epub 2016 Sep 30.
57. MicroRNA-155 regulates the Th17 immune response by targeting Ets-1 in Behçet's disease. Na SY, etal., Clin Exp Rheumatol. 2016 Sep-Oct;34(6 Suppl 102):S56-S63. Epub 2016 Apr 18.
58. MicroRNA-155 is essential for the T cell-mediated control of Helicobacter pylori infection and for the induction of chronic Gastritis and Colitis. Oertli M, etal., J Immunol. 2011 Oct 1;187(7):3578-86. doi: 10.4049/jimmunol.1101772. Epub 2011 Aug 31.
59. miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4. Prossomariti A, etal., Mol Cancer Res. 2018 Dec;16(12):1965-1976. doi: 10.1158/1541-7786.MCR-18-0115. Epub 2018 Aug 2.
60. MicroRNA-146a and microRNA-155 as novel crevicular fluid biomarkers for periodontitis in non-diabetic and type 2 diabetic patients. Radović N, etal., J Clin Periodontol. 2018 Jun;45(6):663-671. doi: 10.1111/jcpe.12888. Epub 2018 May 15.
61. Mouse MP Annotation Import Pipeline RGD automated import pipeline
62. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
63. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
64. Differential intestinal anti-inflammatory effects of Lactobacillus fermentum and Lactobacillus salivarius in DSS mouse colitis: impact on microRNAs expression and microbiota composition. Rodríguez-Nogales A, etal., Mol Nutr Food Res. 2017 Nov;61(11). doi: 10.1002/mnfr.201700144. Epub 2017 Aug 29.
65. Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson's Disease. Sancandi M, etal., Int J Mol Sci. 2020 Apr 15;21(8). pii: ijms21082743. doi: 10.3390/ijms21082743.
66. Role of 3-Acetyl-11-Keto-Beta-Boswellic Acid in Counteracting LPS-Induced Neuroinflammation via Modulation of miRNA-155. Sayed AS, etal., Mol Neurobiol. 2018 Jul;55(7):5798-5808. doi: 10.1007/s12035-017-0801-2. Epub 2017 Oct 27.
67. Circulating and Fecal microRNAs as Biomarkers for Inflammatory Bowel Diseases. Schönauen K, etal., Inflamm Bowel Dis. 2018 Jun 8;24(7):1547-1557. doi: 10.1093/ibd/izy046.
68. Serum MicroRNA-122 and MicroRNA-155: Markers of Disease Progression in Hepatitis C viral infection. Sheneef A, etal., Egypt J Immunol. 2017 Jun;24(2):33-46.
69. Increased duodenal expression of miR-146a and -155 in pediatric Crohn's disease. Szűcs D, etal., World J Gastroenterol. 2016 Jul 14;22(26):6027-35. doi: 10.3748/wjg.v22.i26.6027.
70. [Protective effect of microRNA-155 antisense oligonucleotid on lipopolysaccharide-induced acute lung injury in mice]. Tang J, etal., Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Aug;30(8):743-747. doi: 10.3760/cma.j.issn.2095-4352.2018.08.006.
71. Downregulation of miR-155 attenuates sepsis-induced acute lung injury by targeting SIRT1. Tuerdi B, etal., Int J Clin Exp Pathol. 2018 Sep 1;11(9):4483-4492. eCollection 2018.
72. Circulating Plasma Levels of miR-20b, miR-29b and miR-155 as Predictors of Bevacizumab Efficacy in Patients with Metastatic Colorectal Cancer. Ulivi P, etal., Int J Mol Sci. 2018 Jan 20;19(1). pii: ijms19010307. doi: 10.3390/ijms19010307.
73. MicroRNA 155 Contributes to Host Immunity against Leishmania donovani but Is Not Essential for Resolution of Infection. Varikuti S, etal., Infect Immun. 2019 Jul 23;87(8). pii: IAI.00307-19. doi: 10.1128/IAI.00307-19. Print 2019 Aug.
74. MicroRNA-155 Amplifies Nitric Oxide/cGMP Signaling and Impairs Vascular Angiotensin II Reactivity in Septic Shock. Vasques-Nóvoa F, etal., Crit Care Med. 2018 Sep;46(9):e945-e954. doi: 10.1097/CCM.0000000000003296.
75. MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer. Velazquez KT, etal., Am J Physiol Gastrointest Liver Physiol. 2016 Mar 15;310(6):G347-58. doi: 10.1152/ajpgi.00326.2015. Epub 2016 Jan 7.
76. miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice. Velázquez KT, etal., Physiol Rep. 2017 Sep;5(18). pii: 5/18/e13412. doi: 10.14814/phy2.13412.
77. MicroRNA-155 Deficiency Leads to Decreased Atherosclerosis, Increased White Adipose Tissue Obesity, and Non-alcoholic Fatty Liver Disease: A NOVEL MOUSE MODEL OF OBESITY PARADOX. Virtue A, etal., J Biol Chem. 2017 Jan 27;292(4):1267-1287. doi: 10.1074/jbc.M116.739839. Epub 2016 Nov 17.
78. MiRNA-155 Regulates the Th17/Treg Ratio by Targeting SOCS1 in Severe Acute Pancreatitis. Wang D, etal., Front Physiol. 2018 Jun 8;9:686. doi: 10.3389/fphys.2018.00686. eCollection 2018.
79. Decreased MiR-155 Level in the Peripheral Blood of Non-Alcoholic Fatty Liver Disease Patients may Serve as a Biomarker and may Influence LXR Activity. Wang L, etal., Cell Physiol Biochem. 2016;39(6):2239-2248. doi: 10.1159/000447917. Epub 2016 Nov 7.
80. MicroRNA Microarray-Based Identification of Involvement of miR-155 and miR-19a in Development of Oral Lichen Planus (OLP) by Modulating Th1/Th2 Balance via Targeting eNOS and Toll-Like Receptor 2 (TLR2). Wang L, etal., Med Sci Monit. 2018 May 29;24:3591-3603. doi: 10.12659/MSM.907497.
81. MicroRNA-155 inversely correlates with esophageal cancer progression through regulating tumor-associated macrophage FGF2 expression. Wang P, etal., Biochem Biophys Res Commun. 2018 Sep 5;503(2):452-458. doi: 10.1016/j.bbrc.2018.04.094. Epub 2018 Jun 30.
82. Macrophage micro-RNA-155 promotes lipopolysaccharide-induced acute lung injury in mice and rats. Wang W, etal., Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L494-506. doi: 10.1152/ajplung.00001.2016. Epub 2016 Jul 1.
83. HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines. Wang W, etal., Cell Mol Life Sci. 2018 Jul;75(14):2627-2641. doi: 10.1007/s00018-018-2753-8. Epub 2018 Jan 18.
84. Involvement of the Negative Feedback of IL-33 Signaling in the Anti-Inflammatory Effect of Electro-acupuncture on Allergic Contact Dermatitis via Targeting MicroRNA-155 in Mast Cells. Wang Z, etal., Inflammation. 2018 Jun;41(3):859-869. doi: 10.1007/s10753-018-0740-8.
85. Inhibition of microRNA-155 attenuates concanavalin-A-induced autoimmune hepatitis by regulating Treg/Th17 cell differentiation. Xia G, etal., Can J Physiol Pharmacol. 2018 Dec;96(12):1293-1300. doi: 10.1139/cjpp-2018-0467. Epub 2018 Oct 5.
86. MiR-155 contributes to Th17 cells differentiation in dextran sulfate sodium (DSS)-induced colitis mice via Jarid2. Xu M, etal., Biochem Biophys Res Commun. 2017 Jun 17;488(1):6-14. doi: 10.1016/j.bbrc.2017.04.143. Epub 2017 Apr 28.
87. [Circulating Serum MicroRNA as Diagnostic Biomarkers for Multiple Myeloma]. Xu YN, etal., Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Apr;25(2):471-475. doi: 10.7534/j.issn.1009-2137.2017.02.029.
88. Tanshinone IIA Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice Infected with Porphyromonas gingivalis. Xuan Y, etal., Inflammation. 2017 Oct;40(5):1631-1642. doi: 10.1007/s10753-017-0603-8.
89. Repression of lncRNA NEAT1 enhances the antitumor activity of CD8+T cells against hepatocellular carcinoma via regulating miR-155/Tim-3. Yan K, etal., Int J Biochem Cell Biol. 2019 May;110:1-8. doi: 10.1016/j.biocel.2019.01.019. Epub 2019 Jan 30.
90. The inhibitory effect of Gualou Guizhi Decoction on post-ischemic neuroinflammation via miR-155 in MCAO rats. Yang J, etal., Ann Palliat Med. 2021 Feb;10(2):1370-1379. doi: 10.21037/apm-20-518. Epub 2020 Oct 16.
91. Visualizing the Conversion Process of Alcohol-Induced Fatty Liver to Steatohepatitis in Vivo with a Fluorescent Nanoprobe. Yang L, etal., Anal Chem. 2017 Jun 6;89(11):6196-6201. doi: 10.1021/acs.analchem.7b01144. Epub 2017 May 17.
92. MiR-155 aggravated septic liver injury by oxidative stress-mediated ER stress and mitochondrial dysfunction via targeting Nrf-2. Yang ZB, etal., Exp Mol Pathol. 2018 Dec;105(3):387-394. doi: 10.1016/j.yexmp.2018.09.003. Epub 2018 Sep 13.
93. [Expression of microRNA-155 in inflammatory bowel disease and its clinical significance]. Ye YL, etal., Zhonghua Yi Xue Za Zhi. 2017 Dec 19;97(47):3716-3719. doi: 10.3760/cma.j.issn.0376-2491.2017.47.007.
94. Association of MicroRNA-210 and MicroRNA-155 with severity of preeclampsia. Youssef HMG and Marei ES, Pregnancy Hypertens. 2019 Jul;17:49-53. doi: 10.1016/j.preghy.2019.05.010. Epub 2019 May 10.
95. Fine-tuning the expression of microRNA-155 controls acetaminophen-induced liver inflammation. Yuan K, etal., Int Immunopharmacol. 2016 Nov;40:339-346. doi: 10.1016/j.intimp.2016.09.011. Epub 2016 Sep 24.
96. Expression of miRNA-146a, miRNA-155, IL-2, and TNF-α in inflammatory response to Helicobacter pylori infection associated with cancer progression. Zabaglia LM, etal., Ann Hum Genet. 2018 May;82(3):135-142. doi: 10.1111/ahg.12234. Epub 2017 Dec 18.
97. Decreased miR-155-5p, miR-15a, and miR-186 Expression in Gastric Cancer Is Associated with Advanced Tumor Grade and Metastasis Zare A, etal., Iran Biomed J. 2019 Sep;23(5):338-343. Epub 2019 May 19.
98. A Feedback Loop between MicroRNA 155 (miR-155), Programmed Cell Death 4, and Activation Protein 1 Modulates the Expression of miR-155 and Tumorigenesis in Tongue Cancer. Zargar S, etal., Mol Cell Biol. 2019 Mar 1;39(6). pii: MCB.00410-18. doi: 10.1128/MCB.00410-18. Print 2019 Mar 15.
99. DNA Tetrahedral Nanostructure-Based Electrochemical miRNA Biosensor for Simultaneous Detection of Multiple miRNAs in Pancreatic Carcinoma. Zeng D, etal., ACS Appl Mater Interfaces. 2017 Jul 19;9(28):24118-24125. doi: 10.1021/acsami.7b05981. Epub 2017 Jul 5.
100. Investigating the microRNA-mRNA regulatory network in acute myeloid leukemia. Zhang H, etal., Oncol Lett. 2017 Oct;14(4):3981-3988. doi: 10.3892/ol.2017.6686. Epub 2017 Jul 28.
101. Acupuncture Decreases NF-κB p65, miR-155, and miR-21 and Increases miR-146a Expression in Chronic Atrophic Gastritis Rats. Zhang J, etal., Evid Based Complement Alternat Med. 2016;2016:9404629. doi: 10.1155/2016/9404629. Epub 2016 May 18.
102. MicroRNA-155 promotes tumor growth of human hepatocellular carcinoma by targeting ARID2. Zhang L, etal., Int J Oncol. 2016 Jun;48(6):2425-34. doi: 10.3892/ijo.2016.3465. Epub 2016 Mar 30.
103. Role of miR-155 in the regulation of MMP-16 expression in intervertebral disc degeneration. Zhang WL, etal., J Orthop Res. 2017 Jun;35(6):1323-1334. doi: 10.1002/jor.23313. Epub 2017 Apr 24.
104. MicroRNA-155 expression as a prognostic factor in patients with gallbladder carcinoma after surgical resection. Zhang XL, etal., Int J Clin Exp Med. 2015 Nov 15;8(11):21241-6. eCollection 2015.
105. Activation of PD-1 Protects Intestinal Immune Defense Through IL-10/miR-155 Pathway After Intestinal Ischemia Reperfusion. Zhang XY, etal., Dig Dis Sci. 2018 Dec;63(12):3307-3316. doi: 10.1007/s10620-018-5282-2. Epub 2018 Sep 12.
106. MicroRNA-155 modulates bile duct inflammation by targeting the suppressor of cytokine signaling 1 in biliary atresia. Zhao R, etal., Pediatr Res. 2017 Dec;82(6):1007-1016. doi: 10.1038/pr.2017.87. Epub 2017 Sep 6.
107. Inflammation-Related MicroRNAs Are Associated with Plaque Stability Calculated by IVUS in Coronary Heart Disease Patients. Zhu GF, etal., J Interv Cardiol. 2019 Dec 1;2019:9723129. doi: 10.1155/2019/9723129. eCollection 2019.
108. Hyperlipidemia-Induced MicroRNA-155-5p Improves β-Cell Function by Targeting Mafb. Zhu M, etal., Diabetes. 2017 Dec;66(12):3072-3084. doi: 10.2337/db17-0313. Epub 2017 Sep 29.
Additional References at PubMed
PMID:11675008   PMID:12007417   PMID:15634332   PMID:16369549   PMID:16381832   PMID:17369397   PMID:17463289   PMID:17463290   PMID:17604727   PMID:18055230   PMID:18367535   PMID:18450484  
PMID:18455451   PMID:18481999   PMID:18723672   PMID:18762567   PMID:18794355   PMID:19144316   PMID:19234151   PMID:19359473   PMID:19423639   PMID:19520806   PMID:19596814   PMID:19777054  
PMID:19877012   PMID:20041145   PMID:20133617   PMID:20143464   PMID:20223773   PMID:20413612   PMID:20439436   PMID:20444872   PMID:20548288   PMID:20579867   PMID:20660734   PMID:20668074  
PMID:20888269   PMID:20937844   PMID:21037258   PMID:21062749   PMID:21149603   PMID:21247879   PMID:21267068   PMID:21355095   PMID:21385848   PMID:21397537   PMID:21460854   PMID:21690378  
PMID:21788439   PMID:21807897   PMID:21822254   PMID:21868385   PMID:21986534   PMID:22042248   PMID:22043967   PMID:22096245   PMID:22113163   PMID:22378844   PMID:22408260   PMID:22415194  
PMID:22445295   PMID:22473996   PMID:22509021   PMID:22517757   PMID:22546503   PMID:22558252   PMID:22634176   PMID:22685206   PMID:22685717   PMID:22712528   PMID:22715471   PMID:22771905  
PMID:23041630   PMID:23091595   PMID:23142080   PMID:23143100   PMID:23166327   PMID:23166356   PMID:23169640   PMID:23185331   PMID:23200854   PMID:23221547   PMID:23239859   PMID:23264052  
PMID:23275599   PMID:23422749   PMID:23436936   PMID:23449975   PMID:23487026   PMID:23513069   PMID:23514739   PMID:23560074   PMID:23572582   PMID:23601686   PMID:23603793   PMID:23612310  
PMID:23648819   PMID:23665206   PMID:23666369   PMID:23674757   PMID:23686497   PMID:23797321   PMID:23911388   PMID:23949802   PMID:23951048   PMID:23956210   PMID:23966392   PMID:23991091  
PMID:24084329   PMID:24130493   PMID:24136167   PMID:24227772   PMID:24270517   PMID:24282294   PMID:24291840   PMID:24319262   PMID:24362029   PMID:24363519   PMID:24373357   PMID:24387321  
PMID:24391219   PMID:24444604   PMID:24470395   PMID:24477912   PMID:24486510   PMID:24504735   PMID:24516198   PMID:24531847   PMID:24582962   PMID:24604078   PMID:24630724   PMID:24636235  
PMID:24648472   PMID:24657879   PMID:24675724   PMID:24734904   PMID:24778118   PMID:24804980   PMID:24856900   PMID:24857550   PMID:24891206   PMID:24937178   PMID:24967703   PMID:24969676  
PMID:24990149   PMID:24996169   PMID:25009204   PMID:25015656   PMID:25024218   PMID:25048084   PMID:25126745   PMID:25143000   PMID:25156614   PMID:25156727   PMID:25172909   PMID:25190143  
PMID:25264197   PMID:25288398   PMID:25367574   PMID:25381386   PMID:25381879   PMID:25406379   PMID:25502838   PMID:25548153   PMID:25587068   PMID:25611689   PMID:25625305   PMID:25641586  
PMID:25641956   PMID:25645925   PMID:25651871   PMID:25700796   PMID:25794705   PMID:25799309   PMID:25810298   PMID:25811992   PMID:25846955   PMID:25850724   PMID:25892184   PMID:25911753  
PMID:25916938   PMID:25929465   PMID:25944053   PMID:25972159   PMID:25995365   PMID:26042593   PMID:26062936   PMID:26084661   PMID:26107743   PMID:26121028   PMID:26134658   PMID:26163372  
PMID:26242736   PMID:26251957   PMID:26252010   PMID:26265120   PMID:26337206   PMID:26447227   PMID:26538391   PMID:26539029   PMID:26555429   PMID:26556607   PMID:26574931   PMID:26589288  
PMID:26589478   PMID:26657861   PMID:26670809   PMID:26674874   PMID:26697483   PMID:26787872   PMID:26828700   PMID:26841929   PMID:26850462   PMID:26911687   PMID:26953132   PMID:27052830  
PMID:27070591   PMID:27079875   PMID:27107135   PMID:27135215   PMID:27183599   PMID:27277683   PMID:27294852   PMID:27334594   PMID:27350630   PMID:27363282   PMID:27377409   PMID:27387650  
PMID:27395764   PMID:27447824   PMID:27481129   PMID:27492144   PMID:27509492   PMID:27511021   PMID:27556515   PMID:27559047   PMID:27559048   PMID:27565813   PMID:27593513   PMID:27671445  
PMID:27681624   PMID:27740637   PMID:27746237   PMID:27843203   PMID:27924974   PMID:28110885   PMID:28129114   PMID:28167605   PMID:28174416   PMID:28193481   PMID:28240738   PMID:28241004  
PMID:28256712   PMID:28259135   PMID:28273556   PMID:28278287   PMID:28423578   PMID:28432220   PMID:28473977   PMID:28525390   PMID:28584078   PMID:28612258   PMID:28652200   PMID:28719617  
PMID:28790455   PMID:28871950   PMID:28888763   PMID:28892129   PMID:28910376   PMID:28912267   PMID:28930663   PMID:28942920   PMID:28944921   PMID:28965281   PMID:28967703   PMID:29021573  
PMID:29133016   PMID:29161332   PMID:29217774   PMID:29349090   PMID:29441735   PMID:29459426   PMID:29477204   PMID:29720426   PMID:29767259   PMID:29768211   PMID:29774026   PMID:29792529  
PMID:29852869   PMID:29937276   PMID:29966831   PMID:29967100   PMID:29996893   PMID:30104414   PMID:30144578   PMID:30224821   PMID:30273359   PMID:30280195   PMID:30285793   PMID:30299169  
PMID:30318337   PMID:30356668   PMID:30362213   PMID:30369883   PMID:30459357   PMID:30517011   PMID:30538705   PMID:30577275   PMID:30616426   PMID:30715692   PMID:30717971   PMID:30720115  
PMID:30721153   PMID:30914375   PMID:30944299   PMID:30964175   PMID:31045320   PMID:31089138   PMID:31097471   PMID:31099069   PMID:31173279   PMID:31177529   PMID:31275315   PMID:31317664  
PMID:31405809   PMID:31531958   PMID:31682635   PMID:31736940   PMID:31751318   PMID:31782248   PMID:31819170   PMID:31845227   PMID:31865729   PMID:31876686   PMID:31907997   PMID:31924781  
PMID:31988469   PMID:32040476   PMID:32043657   PMID:32084556   PMID:32090104   PMID:32096189   PMID:32106541   PMID:32161096   PMID:32162171   PMID:32215174   PMID:32240701   PMID:32277342  
PMID:32277848   PMID:32283635   PMID:32308197   PMID:32324763   PMID:32337959   PMID:32436368   PMID:32507875   PMID:32634427   PMID:32666270   PMID:32878636   PMID:32985331   PMID:33037565  
PMID:33110183   PMID:33174081   PMID:33259794   PMID:33293695   PMID:33391256   PMID:33488632   PMID:33524272   PMID:33539779   PMID:33636223   PMID:33674584   PMID:33757809   PMID:33840057  
PMID:33981308   PMID:33985523   PMID:34067440   PMID:34075120   PMID:34081253   PMID:34114683   PMID:34180348   PMID:34284114   PMID:34325129   PMID:34341909   PMID:34453120   PMID:34572101  
PMID:34638868   PMID:34812475   PMID:34865098   PMID:34893074   PMID:34907898   PMID:35018433   PMID:35059323   PMID:35067718   PMID:35179324   PMID:35222806   PMID:35264708   PMID:35294601  
PMID:35347477   PMID:35355364   PMID:35404476   PMID:35545774   PMID:35643451   PMID:35728579   PMID:35795997   PMID:35832084   PMID:35834034   PMID:35915541   PMID:35925680   PMID:35958610  
PMID:36053380   PMID:36076283   PMID:36121133   PMID:36248815   PMID:36319097   PMID:36321836   PMID:36519433   PMID:36598122   PMID:36623778   PMID:36631006   PMID:36764644   PMID:36879321  
PMID:36883849   PMID:37062437   PMID:37070646   PMID:37142295   PMID:37503757   PMID:37524226   PMID:37657048   PMID:37858304   PMID:37878486   PMID:37953267   PMID:38041017   PMID:38150082  
PMID:38159585   PMID:38237377   PMID:38267898   PMID:38373387   PMID:38394221   PMID:38451182   PMID:38508350   PMID:38824863   PMID:38980909   PMID:38987851   PMID:39213866   PMID:39314840  
PMID:39627218  


Genomics

Comparative Map Data
Mir155
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391684,511,028 - 84,511,092 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1684,511,028 - 84,511,092 (+)EnsemblGRCm39 Ensembl
GRCm381684,714,140 - 84,714,204 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1684,714,140 - 84,714,204 (+)EnsemblGRCm38mm10GRCm38
MGSCv371684,714,385 - 84,714,449 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1684,918,138 - 84,918,202 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1646.92NCBI
MIR155
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382125,573,980 - 25,574,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2125,573,980 - 25,574,044 (+)EnsemblGRCh38hg38GRCh38
GRCh372126,946,292 - 26,946,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera2112,129,700 - 12,129,764 (+)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2112,349,435 - 12,349,499 (+)NCBIHuRef
CHM1_12126,506,960 - 26,507,024 (+)NCBICHM1_1
T2T-CHM13v2.02123,931,556 - 23,931,620 (+)NCBIT2T-CHM13v2.0
Mir155
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81137,261,114 - 37,261,178 (+)NCBIGRCr8
mRatBN7.21123,774,654 - 23,774,718 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1123,774,654 - 23,774,718 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1132,481,023 - 32,481,087 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01125,181,422 - 25,181,486 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01124,370,128 - 24,370,192 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01124,176,603 - 24,176,667 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,176,603 - 24,176,667 (+)EnsemblRnor6.0rn6Rnor6.0
Celera1123,614,233 - 23,614,297 (+)NCBICelera
Cytogenetic Map11q11NCBI
MIR155
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13121,078,768 - 21,078,828 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3121,078,758 - 21,078,833 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3121,138,038 - 21,138,098 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03121,132,843 - 21,132,903 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13121,151,558 - 21,151,618 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03121,152,631 - 21,152,691 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03121,627,607 - 21,627,667 (+)NCBIUU_Cfam_GSD_1.0
MIR155
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13189,138,822 - 189,138,902 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113189,138,822 - 189,138,902 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213199,063,344 - 199,063,424 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status (No longer updated)

Predicted Targets
Summary Value
Count of predictions:16052
Count of gene targets:8012
Count of transcripts:12648
Interacting mature miRNAs:mmu-miR-155-3p, mmu-miR-155-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301394Eae11_msusceptibility to experimental allergic encephalomyelitis 11 (mouse)Not determined165356189187562035Mouse
1302194Pgia10_mproteoglycan induced arthritis 10 (mouse)Not determined166860072298008968Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163544664392573008Mouse
1558740Bpq9_mblood pressure QTL 9 (mouse)Not determined166332733697327472Mouse
4141113Tgq28_mtriglyceride QTL 28 (mouse)Not determined6298664696986646Mouse
1301364Lith14_mlithogenic gene 14 (mouse)Not determined165566184689661961Mouse
4142262Lmr18_mleishmaniasis resistance 18 (mouse)Not determined166912761198008968Mouse
11049573Lmr18b_mleishmaniasis resistance 18b (mouse)166912761198008968Mouse
1301598Renf2_mrenal failure 2 (mouse)Not determined167038025298008968Mouse
11049574Lmr18a_mleishmaniasis resistance 18a (mouse)166912761198008968Mouse
11522753Cocia19_mcocaine-induced activity, QTL 19 (mouse)166925448298008968Mouse
1300928Etia_methanol induced activation (mouse)Not determined166331390797314016Mouse
1301125Sluc27_msusceptibility to lung cancer 27 (mouse)Not determined166160864495608764Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
26884416Bzwq5_mbi-zygomatic width QTL 5, 5 week (mouse)163732036284696888Mouse
1301032Tauph_mtau phosphorylation (mouse)Not determined166907613298008968Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000083463
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1684,511,028 - 84,511,092 (+)Ensembl
GRCm38.p6 Ensembl1684,714,140 - 84,714,204 (+)Ensembl
RefSeq Acc Id: NR_029565
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391684,511,028 - 84,511,092 (+)NCBI
GRCm381684,714,140 - 84,714,204 (+)ENTREZGENE
MGSCv371684,714,385 - 84,714,449 (+)RGD
Celera1684,918,138 - 84,918,202 (+)RGD
cM Map16 ENTREZGENE
Sequence:
Promoters
RGD ID:13674274
Promoter ID:EPDNEW_M21286
Type:multiple initiation site
Name:Mir155_1
Description:Mus musculus microRNA 155 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381684,714,205 - 84,714,265EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676840 AgrOrtholog
Ensembl Genes ENSMUSG00000065397 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083463 ENTREZGENE
MGD MGI:2676840 ENTREZGENE
miRBase MI0000177 ENTREZGENE
NCBI Gene 387173 ENTREZGENE
PhenoGen Mir155 PhenoGen
RNAcentral URS0000021B51 RNACentral
  URS00003C3944 RNACentral
  URS0000723DBB RNACentral