Mir96 (microRNA 96) - Rat Genome Database

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Gene: Mir96 (microRNA 96) Mus musculus
Analyze
Symbol: Mir96
Name: microRNA 96
RGD ID: 1608170
MGI Page MGI
Description: Acts upstream of or within with a negative effect on gene expression. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; miRNA-mediated post-transcriptional gene silencing; and neuron development. Is expressed in several structures, including gonad; gut; metanephros; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and autosomal dominant nonsyndromic deafness 50. Orthologous to human MIR96 (microRNA 96).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: Mir; mir-96; Mirn96; mmu-mir-; mmu-mir-96
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39630,169,445 - 30,169,550 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl630,169,445 - 30,169,550 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38630,169,446 - 30,169,551 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl630,169,446 - 30,169,551 (-)Ensemblmm10GRCm38
MGSCv37630,119,446 - 30,119,551 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera630,176,274 - 30,176,379 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.52NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Changes in expression of sensory organ-specific microRNAs in rat dorsal root ganglia in association with mechanical hypersensitivity induced by spinal nerve ligation. Aldrich BT, etal., Neuroscience. 2009 Dec 1;164(2):711-23. doi: 10.1016/j.neuroscience.2009.08.033. Epub 2009 Aug 20.
2. Intrathecal miR-96 inhibits Nav1.3 expression and alleviates neuropathic pain in rat following chronic construction injury. Chen HP, etal., Neurochem Res. 2014 Jan;39(1):76-83.
3. Wnt/β-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion. Leung WK, etal., Cancer Lett. 2015 Jun 28;362(1):97-105. doi: 10.1016/j.canlet.2015.03.023. Epub 2015 Mar 23.
4. miR-96 targets SOX6 and promotes proliferation, migration, and invasion of hepatocellular carcinoma. Li Z and Wang Y, Biochem Cell Biol. 2018 Jun;96(3):365-371. doi: 10.1139/bcb-2017-0183. Epub 2017 Sep 11.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Evaluation of single nucleotide polymorphisms in the miR-183-96-182 cluster in adulthood attention-deficit and hyperactivity disorder (ADHD) and substance use disorders (SUDs). Sanchez-Mora C, etal., Eur Neuropsychopharmacol. 2013 Nov;23(11):1463-73. doi: 10.1016/j.euroneuro.2013.07.002. Epub 2013 Jul 29.
10. Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96. Ubhi K, etal., Eur J Neurosci. 2014 Mar;39(6):1026-41. doi: 10.1111/ejn.12444. Epub 2013 Dec 5.
11. miR-96 and miR-330 overexpressed and targeted AQP5 in lipopolysaccharide-induced rat lung damage of disseminated intravascular coagulation. Zhang Y, etal., Blood Coagul Fibrinolysis. 2014 Oct;25(7):731-7. doi: 10.1097/MBC.0000000000000133.
Additional References at PubMed
PMID:12919684   PMID:15538371   PMID:16369549   PMID:16381832   PMID:17369397   PMID:17597072   PMID:17604727   PMID:17936263   PMID:18184563   PMID:19279690   PMID:19363478   PMID:19602392  
PMID:20215419   PMID:20413612   PMID:20439489   PMID:20478254   PMID:20668074   PMID:21037258   PMID:21245307   PMID:21267068   PMID:21360794   PMID:21518438   PMID:21768104   PMID:21822254  
PMID:22292060   PMID:22889583   PMID:23152916   PMID:23341629   PMID:23646144   PMID:23823476   PMID:23946534   PMID:24446963   PMID:24470395   PMID:24803159   PMID:24927531   PMID:25451232  
PMID:25556186   PMID:25759012   PMID:26041499   PMID:26681446   PMID:26988146   PMID:27035623   PMID:28036389   PMID:28259902   PMID:28430012   PMID:28484004   PMID:28559309   PMID:28819115  
PMID:28941704   PMID:29288578   PMID:29325119   PMID:29476110   PMID:30486773   PMID:30575790   PMID:30578296   PMID:30625496   PMID:30924851   PMID:30973865   PMID:31506178   PMID:31810140  
PMID:32544097   PMID:32618342   PMID:33208381   PMID:33443164   PMID:33493581   PMID:33636225   PMID:33752931   PMID:33850295   PMID:33973871   PMID:34058789   PMID:34193555   PMID:34919120  
PMID:35242136   PMID:35435123   PMID:35481839   PMID:36586536   PMID:36789690   PMID:37536656   PMID:37721476   PMID:38190934   PMID:38355793   PMID:38484719   PMID:38763044   PMID:38826689  
PMID:38985856   PMID:39299667   PMID:39434156  


Genomics

Comparative Map Data
Mir96
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39630,169,445 - 30,169,550 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl630,169,445 - 30,169,550 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38630,169,446 - 30,169,551 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl630,169,446 - 30,169,551 (-)Ensemblmm10GRCm38
MGSCv37630,119,446 - 30,119,551 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera630,176,274 - 30,176,379 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.52NCBI
MIR96
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387129,774,692 - 129,774,769 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7129,774,692 - 129,774,769 (-)Ensemblhg38GRCh38
GRCh377129,414,532 - 129,414,609 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367129,201,767 - 129,201,844 (-)NCBIBuild 36Build 36hg18NCBI36
Celera7124,210,277 - 124,210,354 (-)NCBICelera
Cytogenetic Map7q32.2NCBI
HuRef7123,775,817 - 123,775,894 (-)NCBIHuRef
CHM1_17129,347,923 - 129,348,000 (-)NCBICHM1_1
T2T-CHM13v2.07131,087,826 - 131,087,903 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27128,798,808 - 128,798,885 (-)NCBI
Mir96
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8459,755,841 - 59,755,946 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2458,788,411 - 58,788,516 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl458,788,411 - 58,788,516 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx463,765,533 - 63,765,638 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0459,681,700 - 59,681,805 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0458,083,605 - 58,083,710 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0457,463,366 - 57,463,471 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl457,463,366 - 57,463,471 (-)Ensemblrn6Rnor6.0
Rnor_5.0457,225,167 - 57,225,272 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera453,887,982 - 53,888,087 (-)NCBICelera
Cytogenetic Map4q22NCBI
MIR96
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,068,754 - 7,068,842 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,068,754 - 7,068,842 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha146,754,051 - 6,754,139 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0146,831,753 - 6,831,841 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl146,831,753 - 6,831,841 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1147,037,336 - 7,037,424 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0146,779,495 - 6,779,583 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0146,923,777 - 6,923,865 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
MIR96
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1818,982,506 - 18,982,590 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11818,982,506 - 18,982,590 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21820,030,888 - 20,030,972 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mir96
1 total Variants
miRNA Target Status (No longer updated)

Predicted Targets
Summary Value
Count of predictions:17271
Count of gene targets:8123
Count of transcripts:12977
Interacting mature miRNAs:mmu-miR-96-3p, mmu-miR-96-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797146118069Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122146751333Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
1301131Chol2_mcholesterol 2 (mouse)Not determined6132144495Mouse
1302024Skull7_mskull morphology 7 (mouse)Not determined6132144495Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345291115Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
5491191Mobq2_mmultigenic obesity QTL 2 (mouse)Not determined6132144495Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
1300731Smdq3_msegregation of mitochondrial DNA QTL 3 (mouse)Not determined6424920638249325Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
15039372Nmrs22_mNAFLD-associated magnetic resonance shift 22 (mouse)6147633435476334Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707443297168Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122146751333Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse

Markers in Region
Mir183  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38630,168,943 - 30,169,973UniSTSGRCm38
MGSCv37630,118,943 - 30,119,973UniSTSGRCm37
Celera630,175,771 - 30,176,801UniSTS
cM Map6 UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000083652
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl630,169,445 - 30,169,550 (-)Ensembl
GRCm38.p6 Ensembl630,169,446 - 30,169,551 (-)Ensembl
RefSeq Acc Id: NR_029750
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39630,169,445 - 30,169,550 (-)NCBI
GRCm38630,169,446 - 30,169,551 (-)ENTREZGENE
MGSCv37630,119,446 - 30,119,551 (-)RGD
Celera630,176,274 - 30,176,379 (-)RGD
cM Map6 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3619440 AgrOrtholog
Ensembl Genes ENSMUSG00000065586 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083652 ENTREZGENE
MGD MGI:3619440 ENTREZGENE
miRBase MI0000583 ENTREZGENE
NCBI Gene 723886 ENTREZGENE
PhenoGen Mir96 PhenoGen
RNAcentral URS00000154FC RNACentral
  URS000016FF9C RNACentral
  URS000075A5B2 RNACentral