Mir10a (microRNA 10a) - Rat Genome Database

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Gene: Mir10a (microRNA 10a) Mus musculus
Analyze
Symbol: Mir10a
Name: microRNA 10a
RGD ID: 1608163
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular response to alcohol; cellular response to lipopolysaccharide; and miRNA-mediated post-transcriptional gene silencing. Is expressed in embryo; metanephros; and trunk. Orthologous to human MIR10A (microRNA 10a).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: Mir; miR-; miR-10a; Mirn10a; mmu-mir-; mmu-mir-10a
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,207,991 - 96,208,100 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,207,991 - 96,208,100 (+)EnsemblGRCm39 Ensembl
GRCm381196,317,165 - 96,317,274 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,317,165 - 96,317,274 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,178,479 - 96,178,588 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera11105,968,030 - 105,968,139 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MicroRNA-10a-5p and microRNA-34c-5p in laryngeal epithelial premalignant lesions: differential expression and clinicopathological correlation. Hu Y and Liu H, Eur Arch Otorhinolaryngol. 2015 Feb;272(2):391-9. doi: 10.1007/s00405-014-3299-5. Epub 2014 Sep 30.
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression. Teng Y, etal., Nat Commun. 2017 Feb 17;8:14448. doi: 10.1038/ncomms14448.
5. Elevated circulating microRNA-210 levels in patients with hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations: a potential new biomarker. Zhang Q, etal., Biomarkers. 2013 Feb;18(1):23-9. doi: 10.3109/1354750X.2012.728624. Epub 2012 Oct 10.
6. Restoration of circPSMC3 sensitizes gefitinib-resistant esophageal squamous cell carcinoma cells to gefitinib by regulating miR-10a-5p/PTEN axis. Zhu H, etal., Cell Biol Int. 2021 Jan;45(1):107-116. doi: 10.1002/cbin.11473. Epub 2020 Oct 12.
7. microRNA-10a-5p from gastric cancer cell-derived exosomes enhances viability and migration of human umbilical vein endothelial cells by targeting zinc finger MYND-type containing 11. Zhu J, etal., Bioengineered. 2022 Jan;13(1):496-507. doi: 10.1080/21655979.2021.2009962.
Additional References at PubMed
PMID:12624257   PMID:15361871   PMID:16369549   PMID:16381832   PMID:16943360   PMID:17369397   PMID:17604727   PMID:18452032   PMID:18498749   PMID:18723672   PMID:18762567   PMID:19091803  
PMID:20118242   PMID:20215419   PMID:20413612   PMID:21037258   PMID:21267068   PMID:21518438   PMID:21822254   PMID:21993888   PMID:22068236   PMID:22144232   PMID:22570807   PMID:22629323  
PMID:23072816   PMID:23272089   PMID:23825948   PMID:23863486   PMID:24204315   PMID:24205035   PMID:24500693   PMID:26610149   PMID:26864490   PMID:27292126   PMID:28112253   PMID:30367465  
PMID:31174540   PMID:31275170   PMID:31417547   PMID:31597292   PMID:31668395   PMID:32879620   PMID:33128541   PMID:33819189   PMID:37582765   PMID:38841745  


Genomics

Comparative Map Data
Mir10a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,207,991 - 96,208,100 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,207,991 - 96,208,100 (+)EnsemblGRCm39 Ensembl
GRCm381196,317,165 - 96,317,274 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,317,165 - 96,317,274 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,178,479 - 96,178,588 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera11105,968,030 - 105,968,139 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.83NCBI
MIR10A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381748,579,838 - 48,579,947 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1748,579,838 - 48,579,947 (-)EnsemblGRCh38hg38GRCh38
GRCh371746,657,200 - 46,657,309 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361744,012,198 - 44,012,307 (-)NCBINCBI36Build 36hg18NCBI36
Celera1743,111,353 - 43,111,462 (-)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1742,026,007 - 42,026,116 (-)NCBIHuRef
CHM1_11746,723,164 - 46,723,273 (-)NCBICHM1_1
T2T-CHM13v2.01749,443,427 - 49,443,536 (-)NCBIT2T-CHM13v2.0
Mir10a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81081,779,709 - 81,779,818 (+)NCBIGRCr8
mRatBN7.21081,283,171 - 81,283,280 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1081,283,171 - 81,283,280 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1086,232,157 - 86,232,266 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01085,730,192 - 85,730,301 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01081,122,673 - 81,122,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01084,165,950 - 84,166,059 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1084,165,950 - 84,166,059 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01083,968,682 - 83,968,791 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1080,049,333 - 80,049,442 (+)NCBICelera
Cytogenetic Map10q26NCBI
MIR10A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,842,171 - 24,842,233 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,842,145 - 24,842,248 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha924,306,058 - 24,306,120 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0925,636,582 - 25,636,644 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl925,636,556 - 25,636,659 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1924,404,742 - 24,404,804 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0924,665,341 - 24,665,403 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0924,793,560 - 24,793,622 (-)NCBIUU_Cfam_GSD_1.0
MIR10A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1224,833,627 - 24,833,730 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11224,833,644 - 24,833,723 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,791,267 - 24,791,346 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mir10a
4 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:16138
Count of gene targets:8765
Count of transcripts:13596
Interacting mature miRNAs:mmu-miR-10a-3p, mmu-miR-10a-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
14700796Syncq9_msynovial calcification QTL 9 (mouse)119593782696992826Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
15092049Wsigrme3_mweek six growth rate, maternal effect 3 (mouse)118487732496629512Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
15092057Lgrme3_mlate growth rate, maternal effect 3 (mouse)118487732496629512Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1301491Abbp4_mA/J and C57BL/6 blood pressure 4 (mouse)Not determined118869958899081597Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse
13524529Bodwtq10_mbody wweight QTL 10 (mouse)119067951297699512Mouse

Markers in Region
PMC155209P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,317,253 - 96,317,662UniSTSGRCm38
MGSCv371196,178,567 - 96,178,976UniSTSGRCm37
Celera11105,968,118 - 105,968,527UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.05UniSTS
G38056  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,316,652 - 96,316,850UniSTSGRCm38
MGSCv371196,177,966 - 96,178,164UniSTSGRCm37
Celera11105,967,517 - 105,967,715UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.05UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000083585
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1196,207,991 - 96,208,100 (+)Ensembl
GRCm38.p6 Ensembl1196,317,165 - 96,317,274 (+)Ensembl
RefSeq Acc Id: NR_029784
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391196,207,991 - 96,208,100 (+)NCBI
GRCm381196,317,165 - 96,317,274 (+)ENTREZGENE
MGSCv371196,178,479 - 96,178,588 (+)RGD
Celera11105,968,030 - 105,968,139 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Promoters
RGD ID:8676336
Promoter ID:EPDNEW_M16199
Type:single initiation site
Name:Mir10a_1
Description:Mus musculus microRNA 10a , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381196,317,252 - 96,317,312EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3619064 AgrOrtholog
Ensembl Genes ENSMUSG00000065519 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083585 ENTREZGENE
MGD MGI:3619064 ENTREZGENE
miRBase MI0000685 ENTREZGENE
NCBI Gene 723893 ENTREZGENE
PhenoGen Mir10a PhenoGen
RNAcentral URS000016D2D4 RNACentral
  URS00002F4762 RNACentral
  URS000075A9EC RNACentral