TMEM98 (transmembrane protein 98) - Rat Genome Database

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Gene: TMEM98 (transmembrane protein 98) Homo sapiens
Analyze
Symbol: TMEM98
Name: transmembrane protein 98
RGD ID: 1607062
HGNC Page HGNC:24529
Description: Predicted to be involved in T-helper 1 cell differentiation; negative regulation of myelination; and negative regulation of oligodendrocyte differentiation. Located in endoplasmic reticulum; extracellular exosome; and plasma membrane. Implicated in nanophthalmos.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DKFZp564K1964; TADA1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC100419882   LOC440181  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381732,928,153 - 32,944,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1732,927,910 - 32,945,106 (+)EnsemblGRCh38hg38GRCh38
GRCh371731,255,171 - 31,271,333 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361728,279,041 - 28,292,780 (+)NCBINCBI36Build 36hg18NCBI36
Celera1728,165,912 - 28,179,653 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1727,440,387 - 27,454,132 (+)NCBIHuRef
CHM1_11731,318,008 - 31,331,755 (+)NCBICHM1_1
T2T-CHM13v2.01733,874,221 - 33,890,387 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
Additional References at PubMed
PMID:11076863   PMID:11230166   PMID:11256614   PMID:12477932   PMID:12975309   PMID:15489334   PMID:15489336   PMID:16381901   PMID:21873635   PMID:21900206   PMID:24608572   PMID:24852644  
PMID:25946230   PMID:26392740   PMID:26884835   PMID:28298427   PMID:28611215   PMID:30338788   PMID:31266059   PMID:32236127   PMID:32296183   PMID:32379372   PMID:33203948   PMID:33596443  
PMID:33961781   PMID:35866395   PMID:37419942  


Genomics

Comparative Map Data
TMEM98
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381732,928,153 - 32,944,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1732,927,910 - 32,945,106 (+)EnsemblGRCh38hg38GRCh38
GRCh371731,255,171 - 31,271,333 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361728,279,041 - 28,292,780 (+)NCBINCBI36Build 36hg18NCBI36
Celera1728,165,912 - 28,179,653 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1727,440,387 - 27,454,132 (+)NCBIHuRef
CHM1_11731,318,008 - 31,331,755 (+)NCBICHM1_1
T2T-CHM13v2.01733,874,221 - 33,890,387 (+)NCBIT2T-CHM13v2.0
Tmem98
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391180,701,192 - 80,712,859 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1180,701,001 - 80,712,859 (+)EnsemblGRCm39 Ensembl
GRCm381180,810,366 - 80,822,033 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1180,810,175 - 80,822,033 (+)EnsemblGRCm38mm10GRCm38
MGSCv371180,623,917 - 80,635,535 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361180,626,610 - 80,638,228 (+)NCBIMGSCv36mm8
Celera1190,449,693 - 90,461,311 (+)NCBICelera
Cytogenetic Map11B5NCBI
Tmem98
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81066,293,895 - 66,304,806 (+)NCBIGRCr8
mRatBN7.21065,796,173 - 65,807,082 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1065,796,145 - 65,807,079 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1070,424,184 - 70,435,091 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01069,929,500 - 69,940,415 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01065,390,694 - 65,401,666 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01068,173,380 - 68,184,289 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1068,173,369 - 68,184,320 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01067,842,260 - 67,853,169 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41069,028,338 - 69,039,247 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11069,041,960 - 69,052,867 (+)NCBI
Celera1064,753,814 - 64,764,725 (+)NCBICelera
Cytogenetic Map10q26NCBI
Tmem98
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554817,785,967 - 7,798,575 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554817,788,066 - 7,797,433 (+)NCBIChiLan1.0ChiLan1.0
TMEM98
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21931,525,522 - 31,538,994 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11733,406,671 - 33,420,130 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01723,844,747 - 23,858,390 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11724,136,588 - 24,146,912 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1724,133,357 - 24,146,912 (-)Ensemblpanpan1.1panPan2
TMEM98
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1940,130,421 - 40,144,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl940,128,885 - 40,144,181 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha939,289,554 - 39,303,300 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0940,946,407 - 40,960,152 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl940,944,876 - 40,960,389 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1939,732,288 - 39,746,021 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0940,026,591 - 40,040,523 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0940,101,547 - 40,115,291 (-)NCBIUU_Cfam_GSD_1.0
Tmem98
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560239,187,718 - 39,196,760 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365382,064,696 - 2,074,730 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365382,065,663 - 2,074,678 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM98
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1242,083,553 - 42,100,494 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11242,087,691 - 42,101,152 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21243,758,973 - 43,771,672 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM98
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11626,468,148 - 26,481,681 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1626,468,419 - 26,481,025 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660753,558,456 - 3,571,948 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem98
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624875909,017 - 920,823 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624875909,040 - 920,826 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMEM98
28 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001033504.1(TMEM98):c.413G>A (p.Arg138Lys) single nucleotide variant Malignant melanoma [RCV000071402] Chr17:32936447 [GRCh38]
Chr17:31263465 [GRCh37]
Chr17:28287578 [NCBI36]
Chr17:17q11.2		 not provided
NM_015544.3(TMEM98):c.568_569del (p.Leu190fs) microsatellite Nanophthalmos 4 [RCV001332084] Chr17:32940877..32940878 [GRCh38]
Chr17:31267895..31267896 [GRCh37]
Chr17:17q11.2		 pathogenic
NM_015544.3(TMEM98):c.577G>C (p.Ala193Pro) single nucleotide variant Nanophthalmos 4 [RCV000143786] Chr17:32940889 [GRCh38]
Chr17:31267907 [GRCh37]
Chr17:17q11.2		 pathogenic
GRCh37/hg19 17q11.1-11.2(chr17:25403446-31685464)x3 copy number gain not provided [RCV000762776] Chr17:25403446..31685464 [GRCh37]
Chr17:17q11.1-11.2		 likely pathogenic
NM_015544.3(TMEM98):c.236_263+6del deletion Nanophthalmos 4 [RCV000209982] Chr17:32933276..32933309 [GRCh38]
Chr17:31260294..31260327 [GRCh37]
Chr17:17q11.2		 pathogenic
NM_015544.3(TMEM98):c.587A>C (p.His196Pro) single nucleotide variant Nanophthalmos 4 [RCV000210025] Chr17:32940899 [GRCh38]
Chr17:31267917 [GRCh37]
Chr17:17q11.2		 pathogenic
GRCh37/hg19 17q11.2-12(chr17:30497948-31819040)x1 copy number loss See cases [RCV000447945] Chr17:30497948..31819040 [GRCh37]
Chr17:17q11.2-12		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17q11.2-12(chr17:29578241-32142196)x1 copy number loss See cases [RCV000511107] Chr17:29578241..32142196 [GRCh37]
Chr17:17q11.2-12		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
NM_015544.3(TMEM98):c.247T>C (p.Trp83Arg) single nucleotide variant not provided [RCV000973555] Chr17:32933289 [GRCh38]
Chr17:31260307 [GRCh37]
Chr17:17q11.2		 benign
NM_015544.3(TMEM98):c.504C>T (p.His168=) single nucleotide variant not provided [RCV000973216] Chr17:32940816 [GRCh38]
Chr17:31267834 [GRCh37]
Chr17:17q11.2		 benign
NM_015544.3(TMEM98):c.13G>T (p.Val5Leu) single nucleotide variant Inborn genetic diseases [RCV003272034] Chr17:32931541 [GRCh38]
Chr17:31258559 [GRCh37]
Chr17:17q11.2		 uncertain significance
GRCh37/hg19 17p11.2-q21.2(chr17:21690653-38772647)x3 copy number gain not provided [RCV000846852] Chr17:21690653..38772647 [GRCh37]
Chr17:17p11.2-q21.2		 pathogenic
GRCh37/hg19 17q11.2-12(chr17:29989741-32355632) copy number loss Nanophthalmos 4 [RCV001260292] Chr17:29989741..32355632 [GRCh37]
Chr17:17q11.2-12		 pathogenic
GRCh37/hg19 17q11.2-12(chr17:30497948-31819040) copy number loss not specified [RCV002052592] Chr17:30497948..31819040 [GRCh37]
Chr17:17q11.2-12		 uncertain significance
NM_015544.3(TMEM98):c.401G>A (p.Arg134Gln) single nucleotide variant Inborn genetic diseases [RCV002729635] Chr17:32936435 [GRCh38]
Chr17:31263453 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.167A>C (p.Gln56Pro) single nucleotide variant Inborn genetic diseases [RCV002884504] Chr17:32933209 [GRCh38]
Chr17:31260227 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.118C>T (p.Arg40Cys) single nucleotide variant Inborn genetic diseases [RCV002703343] Chr17:32931646 [GRCh38]
Chr17:31258664 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.460C>T (p.Leu154Phe) single nucleotide variant Inborn genetic diseases [RCV002679509] Chr17:32939523 [GRCh38]
Chr17:31266541 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.415G>A (p.Val139Met) single nucleotide variant Inborn genetic diseases [RCV003210538] Chr17:32939478 [GRCh38]
Chr17:31266496 [GRCh37]
Chr17:17q11.2		 uncertain significance
GRCh37/hg19 17q11.2-12(chr17:30572862-35843988) copy number loss Chromosome 17q12 deletion syndrome [RCV003319594] Chr17:30572862..35843988 [GRCh37]
Chr17:17q11.2-12		 pathogenic
NM_015544.3(TMEM98):c.97C>T (p.Arg33Trp) single nucleotide variant Inborn genetic diseases [RCV003359307] Chr17:32931625 [GRCh38]
Chr17:31258643 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.131+9G>C single nucleotide variant TMEM98-related disorder [RCV003974374] Chr17:32931668 [GRCh38]
Chr17:31258686 [GRCh37]
Chr17:17q11.2		 benign
NM_015544.3(TMEM98):c.378C>T (p.Ser126=) single nucleotide variant TMEM98-related disorder [RCV003912208] Chr17:32936412 [GRCh38]
Chr17:31263430 [GRCh37]
Chr17:17q11.2		 likely benign
NM_015544.3(TMEM98):c.468C>T (p.Asp156=) single nucleotide variant TMEM98-related disorder [RCV003897128] Chr17:32939531 [GRCh38]
Chr17:31266549 [GRCh37]
Chr17:17q11.2		 likely benign
NM_015544.3(TMEM98):c.432G>T (p.Lys144Asn) single nucleotide variant Inborn genetic diseases [RCV004470602] Chr17:32939495 [GRCh38]
Chr17:31266513 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.175C>A (p.Pro59Thr) single nucleotide variant Inborn genetic diseases [RCV004470600] Chr17:32933217 [GRCh38]
Chr17:31260235 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.391G>A (p.Val131Met) single nucleotide variant Inborn genetic diseases [RCV004470601] Chr17:32936425 [GRCh38]
Chr17:31263443 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.469G>A (p.Ala157Thr) single nucleotide variant Inborn genetic diseases [RCV004679870] Chr17:32939532 [GRCh38]
Chr17:31266550 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.436A>C (p.Met146Leu) single nucleotide variant Inborn genetic diseases [RCV004679871] Chr17:32939499 [GRCh38]
Chr17:31266517 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.610G>A (p.Ala204Thr) single nucleotide variant Inborn genetic diseases [RCV004679872] Chr17:32940922 [GRCh38]
Chr17:31267940 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.307A>G (p.Thr103Ala) single nucleotide variant Inborn genetic diseases [RCV004966953] Chr17:32936341 [GRCh38]
Chr17:31263359 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.291C>G (p.Ile97Met) single nucleotide variant Inborn genetic diseases [RCV004966954] Chr17:32934318 [GRCh38]
Chr17:31261336 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.19G>A (p.Val7Ile) single nucleotide variant Inborn genetic diseases [RCV004966951] Chr17:32931547 [GRCh38]
Chr17:31258565 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.379G>A (p.Asp127Asn) single nucleotide variant Inborn genetic diseases [RCV004966952] Chr17:32936413 [GRCh38]
Chr17:31263431 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.482C>A (p.Ala161Asp) single nucleotide variant Inborn genetic diseases [RCV004966955] Chr17:32940794 [GRCh38]
Chr17:31267812 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_015544.3(TMEM98):c.550G>T (p.Asp184Tyr) single nucleotide variant Inborn genetic diseases [RCV004966956] Chr17:32940862 [GRCh38]
Chr17:31267880 [GRCh37]
Chr17:17q11.2		 uncertain significance
miRNA Target Status (No longer updated)

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR342hsa-miR-342-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Target Of
Summary Value
Count of predictions:3478
Count of miRNA genes:1181
Interacting mature miRNAs:1487
Transcripts:ENST00000261713, ENST00000394642, ENST00000395149, ENST00000439138, ENST00000578289, ENST00000579849, ENST00000582227, ENST00000583120, ENST00000583437
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298406BP16_HBlood pressure QTL 16 (human)0.0004Blood pressurehypertension susceptibility171477864740778647Human
596980829GWAS1100348_Hmemory performance, sex interaction measurement QTL GWAS1100348 (human)0.000003memory performance, sex interaction measurement173294136032941361Human
597135288GWAS1231362_Hmemory performance, sex interaction measurement QTL GWAS1231362 (human)0.000003memory performance, sex interaction measurement173294136032941361Human

Markers in Region
RH93761  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371731,268,115 - 31,268,253UniSTSGRCh37
Build 361728,292,228 - 28,292,366RGDNCBI36
Celera1728,179,101 - 28,179,239RGD
Cytogenetic Map17q11.2UniSTS
HuRef1727,453,580 - 27,453,718UniSTS
GeneMap99-GB4 RH Map17284.76UniSTS
RH69576  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371731,268,056 - 31,268,240UniSTSGRCh37
Build 361728,292,169 - 28,292,353RGDNCBI36
Celera1728,179,042 - 28,179,226RGD
Cytogenetic Map17q11.2UniSTS
HuRef1727,453,521 - 27,453,705UniSTS
GeneMap99-GB4 RH Map17283.96UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2438 2788 2243 4970 1724 2350 6 624 1742 465 2269 7097 6265 52 3732 1 849 1741 1616 174 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_034264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001033504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_015544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC084809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF132000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL117619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX061600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX061642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY358573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC106911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ228781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR457125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000261713   ⟹   ENSP00000261713
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1732,928,071 - 32,940,977 (+)Ensembl
Ensembl Acc Id: ENST00000394642   ⟹   ENSP00000378138
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1732,927,910 - 32,941,613 (+)Ensembl
Ensembl Acc Id: ENST00000395149   ⟹   ENSP00000398446
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1732,928,045 - 32,936,447 (+)Ensembl
Ensembl Acc Id: ENST00000439138   ⟹   ENSP00000406394
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1732,928,210 - 32,940,978 (+)Ensembl
Ensembl Acc Id: ENST00000578289   ⟹   ENSP00000464537
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1732,928,204 - 32,945,106 (+)Ensembl
Ensembl Acc Id: ENST00000579849   ⟹   ENSP00000463245
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1732,928,153 - 32,944,315 (+)Ensembl
Ensembl Acc Id: ENST00000582227
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1732,928,204 - 32,934,363 (+)Ensembl
Ensembl Acc Id: ENST00000583120
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1732,931,387 - 32,936,468 (+)Ensembl
Ensembl Acc Id: ENST00000583437   ⟹   ENSP00000463539
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1732,931,034 - 32,934,308 (+)Ensembl
RefSeq Acc Id: NM_001033504   ⟹   NP_001028676
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381732,928,153 - 32,944,315 (+)NCBI
GRCh371731,254,928 - 31,268,667 (+)RGD
Build 361728,279,041 - 28,292,780 (+)NCBI Archive
Celera1728,165,912 - 28,179,653 (+)RGD
HuRef1727,440,387 - 27,454,132 (+)RGD
CHM1_11731,318,008 - 31,331,755 (+)NCBI
T2T-CHM13v2.01733,874,221 - 33,890,387 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001301746   ⟹   NP_001288675
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381732,928,153 - 32,944,315 (+)NCBI
CHM1_11731,318,008 - 31,331,755 (+)NCBI
T2T-CHM13v2.01733,874,221 - 33,890,387 (+)NCBI
Sequence:
RefSeq Acc Id: NM_015544   ⟹   NP_056359
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381732,928,153 - 32,944,315 (+)NCBI
GRCh371731,254,928 - 31,268,667 (+)RGD
Build 361728,279,041 - 28,292,780 (+)NCBI Archive
Celera1728,165,912 - 28,179,653 (+)RGD
HuRef1727,440,387 - 27,454,132 (+)RGD
CHM1_11731,318,008 - 31,331,755 (+)NCBI
T2T-CHM13v2.01733,874,221 - 33,890,387 (+)NCBI
Sequence:
RefSeq Acc Id: NP_056359   ⟸   NM_015544
- UniProtKB: E1P631 (UniProtKB/Swiss-Prot),   Q9UFK2 (UniProtKB/Swiss-Prot),   Q9Y2Y6 (UniProtKB/Swiss-Prot),   B2R8Z5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001028676   ⟸   NM_001033504
- UniProtKB: E1P631 (UniProtKB/Swiss-Prot),   Q9UFK2 (UniProtKB/Swiss-Prot),   Q9Y2Y6 (UniProtKB/Swiss-Prot),   B2R8Z5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001288675   ⟸   NM_001301746
- UniProtKB: E1P631 (UniProtKB/Swiss-Prot),   Q9UFK2 (UniProtKB/Swiss-Prot),   Q9Y2Y6 (UniProtKB/Swiss-Prot),   B2R8Z5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000406394   ⟸   ENST00000439138
Ensembl Acc Id: ENSP00000463539   ⟸   ENST00000583437
Ensembl Acc Id: ENSP00000464537   ⟸   ENST00000578289
Ensembl Acc Id: ENSP00000261713   ⟸   ENST00000261713
Ensembl Acc Id: ENSP00000463245   ⟸   ENST00000579849
Ensembl Acc Id: ENSP00000378138   ⟸   ENST00000394642
Ensembl Acc Id: ENSP00000398446   ⟸   ENST00000395149

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Y2Y6-F1-model_v2 AlphaFold Q9Y2Y6 1-226 view protein structure

Promoters
RGD ID:6794634
Promoter ID:HG_KWN:25742
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:NM_001033504,   NM_015544,   OTTHUMT00000256374,   OTTHUMT00000256375
Position:
Human AssemblyChrPosition (strand)Source
Build 361728,279,036 - 28,279,536 (+)MPROMDB
RGD ID:7234571
Promoter ID:EPDNEW_H23032
Type:initiation region
Name:TMEM98_2
Description:transmembrane protein 98
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23033  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381732,927,886 - 32,927,946EPDNEW
RGD ID:7234577
Promoter ID:EPDNEW_H23033
Type:initiation region
Name:TMEM98_1
Description:transmembrane protein 98
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23032  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381732,928,204 - 32,928,264EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:24529 AgrOrtholog
COSMIC TMEM98 COSMIC
Ensembl Genes ENSG00000006042 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000261713.8 UniProtKB/TrEMBL
  ENST00000394642 ENTREZGENE
  ENST00000394642.7 UniProtKB/Swiss-Prot
  ENST00000395149.6 UniProtKB/TrEMBL
  ENST00000439138 ENTREZGENE
  ENST00000439138.5 UniProtKB/TrEMBL
  ENST00000578289.5 UniProtKB/TrEMBL
  ENST00000579849 ENTREZGENE
  ENST00000579849.6 UniProtKB/Swiss-Prot
  ENST00000583437.2 UniProtKB/TrEMBL
Gene3D-CATH I/LWEQ domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000006042 GTEx
HGNC ID HGNC:24529 ENTREZGENE
Human Proteome Map TMEM98 Human Proteome Map
InterPro TMEM98 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:26022 UniProtKB/Swiss-Prot
NCBI Gene 26022 ENTREZGENE
OMIM 615949 OMIM
PANTHER PTHR32510 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 98 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 98 UniProtKB/TrEMBL
PharmGKB PA142670747 PharmGKB
UniProt A0AUK5_HUMAN UniProtKB/TrEMBL
  B2R8Z5 ENTREZGENE, UniProtKB/TrEMBL
  C9J3Y0_HUMAN UniProtKB/TrEMBL
  C9J6Q8_HUMAN UniProtKB/TrEMBL
  E1P631 ENTREZGENE
  J3QLG7_HUMAN UniProtKB/TrEMBL
  J3QS57_HUMAN UniProtKB/TrEMBL
  J9JIC8_HUMAN UniProtKB/TrEMBL
  Q9UFK2 ENTREZGENE
  Q9Y2Y6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary E1P631 UniProtKB/Swiss-Prot
  Q9UFK2 UniProtKB/Swiss-Prot