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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | DBNL | Human | 1,2-dimethylhydrazine | increases expression | ISO | Dbnl (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of DBNL mRNA | CTD | PMID:22206623 | DBNL | Human | 1,2-dimethylhydrazine | multiple interactions | ISO | Dbnl (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of DBNL mRNA] | CTD | PMID:22206623 | DBNL | Human | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31675489 | DBNL | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dbnl (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DBNL mRNA | CTD | PMID:21570461 | DBNL | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DBNL mRNA | CTD | PMID:34747641 | DBNL | Human | 2-methoxyethanol | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | methyl cellosolve results in increased expression of DBNL mRNA | CTD | PMID:21061450 | DBNL | Human | 3,3',5,5'-tetrabromobisphenol A | decreases expression | EXP | | 6480464 | tetrabromobisphenol A results in decreased expression of DBNL protein | CTD | PMID:31675489 | DBNL | Human | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of DBNL protein | CTD | PMID:34186270 | DBNL | Human | 6-propyl-2-thiouracil | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of DBNL mRNA | CTD | PMID:30047161 | DBNL | Human | acetamide | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | acetamide results in increased expression of DBNL mRNA | CTD | PMID:31881176 | DBNL | Human | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of DBNL mRNA | CTD | PMID:32763439 | DBNL | Human | amitrole | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of DBNL mRNA | CTD | PMID:30047161 | DBNL | Human | ammonium chloride | affects expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of DBNL mRNA | CTD | PMID:16483693 | DBNL | Human | antirheumatic drug | decreases expression | EXP | | 6480464 | Antirheumatic Agents results in decreased expression of DBNL mRNA | CTD | PMID:24449571 | DBNL | Human | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of DBNL mRNA | CTD | PMID:33212167 | DBNL | Human | arsenous acid | increases cleavage | EXP | | 6480464 | Arsenic Trioxide results in increased cleavage of DBNL protein | CTD | PMID:15637062 | DBNL | Human | arsenous acid | multiple interactions | EXP | | 6480464 | benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Arsenic Trioxide results in increased cleavage of DBNL protein] | CTD | PMID:15637062 | DBNL | Human | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of DBNL mRNA | CTD | PMID:22378314 | DBNL | Human | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of DBNL promoter | CTD | PMID:27901495 | DBNL | Human | beta-lapachone | decreases expression | EXP | | 6480464 | beta-lapachone results in decreased expression of DBNL mRNA | CTD | PMID:38218311 | DBNL | Human | beta-lapachone | increases expression | EXP | | 6480464 | beta-lapachone results in increased expression of DBNL mRNA | CTD | PMID:38218311 | DBNL | Human | bisphenol A | affects expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of DBNL mRNA | CTD | PMID:25181051 | DBNL | Human | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DBNL protein | CTD | PMID:34186270 and PMID:37567409 | DBNL | Human | bisphenol A | decreases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of DBNL mRNA | CTD | PMID:34947998 | DBNL | Human | bisphenol A | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of DBNL mRNA | CTD | PMID:31129395 | DBNL | Human | bisphenol AF | increases expression | EXP | | 6480464 | bisphenol AF results in increased expression of DBNL protein | CTD | PMID:34186270 | DBNL | Human | Brodifacoum | decreases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | bromfenacoum results in decreased expression of DBNL protein | CTD | PMID:28903499 | DBNL | Human | caffeine | affects phosphorylation | EXP | | 6480464 | Caffeine affects the phosphorylation of DBNL protein | CTD | PMID:35688186 | DBNL | Human | carbon nanotube | increases expression | ISO | Dbnl (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of DBNL mRNA | CTD | PMID:25554681 | DBNL | Human | ceric oxide | decreases expression | EXP | | 6480464 | ceric oxide analog results in decreased expression of DBNL mRNA | CTD | PMID:24821434 | DBNL | Human | chlorpyrifos | increases expression | ISO | Dbnl (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of DBNL mRNA | CTD | PMID:37019170 | DBNL | Human | chromium(6+) | multiple interactions | EXP | | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of DBNL mRNA | CTD | PMID:38479592 | DBNL | Human | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of DBNL mRNA | CTD | PMID:19561079 | DBNL | Human | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of DBNL mRNA | CTD | PMID:19320972 | DBNL | Human | copper atom | multiple interactions | EXP | | 6480464 | [Chelating Agents binds to Copper] which results in decreased expression of DBNL mRNA | CTD | PMID:31162603 | DBNL | Human | copper(0) | multiple interactions | EXP | | 6480464 | [Chelating Agents binds to Copper] which results in decreased expression of DBNL mRNA | CTD | PMID:31162603 | DBNL | Human | coumarin | decreases phosphorylation | EXP | | 6480464 | coumarin results in decreased phosphorylation of DBNL protein | CTD | PMID:35688186 | DBNL | Human | crocidolite asbestos | affects expression | EXP | | 6480464 | Asbestos and Crocidolite affects the expression of DBNL mRNA | CTD | PMID:17331233 | DBNL | Human | decabromodiphenyl ether | decreases expression | EXP | | 6480464 | decabromobiphenyl ether results in decreased expression of DBNL protein | CTD | PMID:31675489 | DBNL | Human | dehydroepiandrosterone | decreases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | Dehydroepiandrosterone results in decreased expression of DBNL mRNA | CTD | PMID:16940010 | DBNL | Human | diarsenic trioxide | multiple interactions | EXP | | 6480464 | benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Arsenic Trioxide results in increased cleavage of DBNL protein] | CTD | PMID:15637062 | DBNL | Human | diarsenic trioxide | increases cleavage | EXP | | 6480464 | Arsenic Trioxide results in increased cleavage of DBNL protein | CTD | PMID:15637062 | DBNL | Human | dibutyl phthalate | decreases expression | ISO | Dbnl (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of DBNL mRNA | CTD | PMID:17361019 | DBNL | Human | diuron | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | Diuron results in increased expression of DBNL mRNA | CTD | PMID:21551480 | DBNL | Human | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of DBNL mRNA | CTD | PMID:35967413 | DBNL | Human | enzyme inhibitor | multiple interactions | EXP | | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of DBNL protein | CTD | PMID:23301498 | DBNL | Human | epoxiconazole | increases expression | ISO | Dbnl (Mus musculus) | 6480464 | epoxiconazole results in increased expression of DBNL mRNA | CTD | PMID:35436446 | DBNL | Human | flutamide | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of DBNL mRNA | CTD | PMID:24136188 | DBNL | Human | folic acid | multiple interactions | ISO | Dbnl (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of DBNL mRNA] | CTD | PMID:22206623 | DBNL | Human | FR900359 | affects phosphorylation | EXP | | 6480464 | FR900359 affects the phosphorylation of DBNL protein | CTD | PMID:37730182 | DBNL | Human | hexadecanoic acid | decreases phosphorylation | EXP | | 6480464 | Palmitic Acid results in decreased phosphorylation of DBNL protein | CTD | PMID:28073184 | DBNL | Human | hydrogen peroxide | multiple interactions | ISO | Dbnl (Mus musculus) | 6480464 | [Hydrogen Peroxide co-treated with N-(oxo-5 more ... | CTD | PMID:31494107 | DBNL | Human | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of DBNL protein | CTD | PMID:32959892 | DBNL | Human | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of DBNL mRNA | CTD | PMID:28903495 | DBNL | Human | Mesaconitine | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | mesaconitine results in increased expression of DBNL protein | CTD | PMID:37182599 | DBNL | Human | methimazole | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of DBNL mRNA | CTD | PMID:30047161 | DBNL | Human | nickel atom | increases expression | EXP | | 6480464 | Nickel results in increased expression of DBNL mRNA | CTD | PMID:24768652 and PMID:25583101 | DBNL | Human | nitrates | multiple interactions | ISO | Dbnl (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of DBNL mRNA | CTD | PMID:35964746 | DBNL | Human | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of DBNL mRNA | CTD | PMID:35430440 | DBNL | Human | paracetamol | affects expression | ISO | Dbnl (Mus musculus) | 6480464 | Acetaminophen affects the expression of DBNL mRNA | CTD | PMID:17562736 | DBNL | Human | pentachlorophenol | increases expression | ISO | Dbnl (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of DBNL mRNA | CTD | PMID:23892564 | DBNL | Human | perfluorooctanoic acid | decreases expression | ISO | Dbnl (Mus musculus) | 6480464 | perfluorooctanoic acid results in decreased expression of DBNL protein | CTD | PMID:28126411 | DBNL | Human | pirinixic acid | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | pirinixic acid results in increased expression of DBNL mRNA | CTD | PMID:19162173 | DBNL | Human | pirinixic acid | decreases expression | ISO | Dbnl (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of DBNL mRNA | CTD | PMID:17426115 | DBNL | Human | progesterone | affects expression | ISO | Dbnl (Mus musculus) | 6480464 | Progesterone affects the expression of DBNL mRNA | CTD | PMID:17251523 | DBNL | Human | SB 431542 | multiple interactions | EXP | | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of DBNL protein | CTD | PMID:37664457 | DBNL | Human | sulfadimethoxine | increases expression | ISO | Dbnl (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of DBNL mRNA | CTD | PMID:30047161 | DBNL | Human | thapsigargin | decreases expression | EXP | | 6480464 | Thapsigargin results in decreased expression of DBNL mRNA | CTD | PMID:22378314 | DBNL | Human | titanium dioxide | increases expression | ISO | Dbnl (Mus musculus) | 6480464 | titanium dioxide results in increased expression of DBNL mRNA | CTD | PMID:29264374 | DBNL | Human | titanium dioxide | decreases methylation | ISO | Dbnl (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of DBNL gene | CTD | PMID:35295148 | DBNL | Human | titanium dioxide | increases methylation | ISO | Dbnl (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of DBNL promoter | CTD | PMID:35295148 | DBNL | Human | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of DBNL mRNA | CTD | PMID:37042841 | DBNL | Human | tunicamycin | decreases expression | EXP | | 6480464 | Tunicamycin results in decreased expression of DBNL mRNA | CTD | PMID:22378314 and PMID:29453283 | DBNL | Human | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of DBNL mRNA | CTD | PMID:28818685 | DBNL | Human | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of DBNL mRNA | CTD | PMID:25979313 | |