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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | PAIP2B | Human | 1,2-dimethylhydrazine | multiple interactions | ISO | Paip2b (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PAIP2B mRNA | CTD | PMID:22206623 | PAIP2B | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Paip2b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PAIP2B mRNA | CTD | PMID:21570461 and PMID:24680724 | PAIP2B | Human | 2-hydroxypropanoic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of PAIP2B mRNA | CTD | PMID:30851411 | PAIP2B | Human | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PAIP2B mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PAIP2B mRNA | CTD | PMID:28628672 | PAIP2B | Human | 6-propyl-2-thiouracil | decreases expression | ISO | Paip2b (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of PAIP2B mRNA | CTD | PMID:30047161 | PAIP2B | Human | aflatoxin B1 | increases expression | ISO | Paip2b (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PAIP2B mRNA | CTD | PMID:19770486 | PAIP2B | Human | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of PAIP2B mRNA | CTD | PMID:22100608 | PAIP2B | Human | benzo[a]pyrene | increases expression | ISO | Paip2b (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PAIP2B mRNA | CTD | PMID:22228805 | PAIP2B | Human | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of PAIP2B mRNA | CTD | PMID:32234424 | PAIP2B | Human | bis(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in decreased expression of PAIP2B mRNA | CTD | PMID:31163220 | PAIP2B | Human | bisphenol A | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PAIP2B mRNA | CTD | PMID:28628672 | PAIP2B | Human | bisphenol F | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PAIP2B mRNA | CTD | PMID:28628672 | PAIP2B | Human | bisphenol F | increases expression | ISO | Paip2b (Mus musculus) | 6480464 | bisphenol F results in increased expression of PAIP2B mRNA | CTD | PMID:38685157 | PAIP2B | Human | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of PAIP2B protein | CTD | PMID:38185225 | PAIP2B | Human | carbon nanotube | increases expression | ISO | Paip2b (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of PAIP2B mRNA | CTD | PMID:25554681 | PAIP2B | Human | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of PAIP2B mRNA | CTD | PMID:27392435 | PAIP2B | Human | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PAIP2B mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PAIP2B mRNA | CTD | PMID:28628672 | PAIP2B | Human | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAIP2B mRNA | CTD | PMID:27188386 | PAIP2B | Human | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of PAIP2B mRNA | CTD | PMID:29803840 | PAIP2B | Human | endosulfan | increases expression | ISO | Paip2b (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of PAIP2B mRNA | CTD | PMID:29391264 | PAIP2B | Human | ethanol | multiple interactions | ISO | Paip2b (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of PAIP2B mRNA | CTD | PMID:30319688 | PAIP2B | Human | folic acid | multiple interactions | ISO | Paip2b (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PAIP2B mRNA | CTD | PMID:22206623 | PAIP2B | Human | herbicide | increases expression | EXP | | 6480464 | Herbicides results in increased expression of PAIP2B mRNA | CTD | PMID:28711546 | PAIP2B | Human | hydroquinone | decreases expression | EXP | | 6480464 | hydroquinone results in decreased expression of PAIP2B mRNA | CTD | PMID:31256213 | PAIP2B | Human | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PAIP2B mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PAIP2B mRNA | CTD | PMID:28628672 | PAIP2B | Human | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of PAIP2B mRNA | CTD | PMID:28903495 | PAIP2B | Human | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of PAIP2B mRNA | CTD | PMID:28988120 | PAIP2B | Human | lipopolysaccharide | multiple interactions | EXP | | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PAIP2B mRNA | CTD | PMID:35811015 | PAIP2B | Human | methimazole | decreases expression | ISO | Paip2b (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of PAIP2B mRNA | CTD | PMID:30047161 | PAIP2B | Human | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of PAIP2B mRNA | CTD | PMID:23179753 and PMID:27188386 | PAIP2B | Human | nickel atom | decreases expression | EXP | | 6480464 | Nickel results in decreased expression of PAIP2B mRNA | CTD | PMID:24768652 and PMID:25583101 | PAIP2B | Human | niclosamide | increases expression | EXP | | 6480464 | Niclosamide results in increased expression of PAIP2B mRNA | CTD | PMID:36318118 | PAIP2B | Human | paracetamol | increases expression | ISO | Paip2b (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of PAIP2B mRNA | CTD | PMID:33387578 | PAIP2B | Human | perfluorononanoic acid | decreases expression | EXP | | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of PAIP2B mRNA | CTD | PMID:32588087 | PAIP2B | Human | rac-lactic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of PAIP2B mRNA | CTD | PMID:30851411 | PAIP2B | Human | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | EXP | | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PAIP2B mRNA | CTD | PMID:35811015 | PAIP2B | Human | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAIP2B mRNA | CTD | PMID:27188386 | PAIP2B | Human | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide analog results in decreased expression of PAIP2B mRNA | CTD | PMID:25895662 | PAIP2B | Human | sodium arsenite | affects methylation | EXP | | 6480464 | sodium arsenite affects the methylation of PAIP2B gene | CTD | PMID:28589171 | PAIP2B | Human | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of PAIP2B mRNA | CTD | PMID:31533062 | PAIP2B | Human | tetrachloromethane | decreases expression | ISO | Paip2b (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of PAIP2B mRNA | CTD | PMID:33387578 | PAIP2B | Human | thimerosal | decreases expression | EXP | | 6480464 | Thimerosal results in decreased expression of PAIP2B mRNA | CTD | PMID:27188386 | PAIP2B | Human | titanium dioxide | decreases expression | ISO | Paip2b (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PAIP2B mRNA | CTD | PMID:29264374 | PAIP2B | Human | titanium dioxide | decreases methylation | ISO | Paip2b (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PAIP2B gene and titanium dioxide results in decreased methylation of PAIP2B promoter | CTD | PMID:35295148 | PAIP2B | Human | trichostatin A | affects expression | EXP | | 6480464 | trichostatin A affects the expression of PAIP2B mRNA | CTD | PMID:28542535 | PAIP2B | Human | triclosan | decreases expression | EXP | | 6480464 | Triclosan results in decreased expression of PAIP2B mRNA | CTD | PMID:30510588 | PAIP2B | Human | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of PAIP2B mRNA | CTD | PMID:37042841 | PAIP2B | Human | triptonide | increases expression | ISO | Paip2b (Mus musculus) | 6480464 | triptonide results in increased expression of PAIP2B mRNA | CTD | PMID:33045310 | PAIP2B | Human | tris(2-butoxyethyl) phosphate | affects expression | EXP | | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of PAIP2B mRNA | CTD | PMID:29024780 | PAIP2B | Human | uranium atom | affects expression | EXP | | 6480464 | Uranium affects the expression of PAIP2B mRNA | CTD | PMID:15672453 | PAIP2B | Human | valproic acid | affects expression | ISO | Paip2b (Mus musculus) | 6480464 | Valproic Acid affects the expression of PAIP2B mRNA | CTD | PMID:17292431 | PAIP2B | Human | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of PAIP2B mRNA | CTD | PMID:19101580 more ... | PAIP2B | Human | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAIP2B mRNA | CTD | PMID:27188386 | PAIP2B | Human | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of PAIP2B mRNA | CTD | PMID:37505509 | |