SNRNP27 (small nuclear ribonucleoprotein U4/U6.U5 subunit 27) - Rat Genome Database

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Gene: SNRNP27 (small nuclear ribonucleoprotein U4/U6.U5 subunit 27) Homo sapiens
Analyze
Symbol: SNRNP27
Name: small nuclear ribonucleoprotein U4/U6.U5 subunit 27
RGD ID: 1605404
HGNC Page HGNC:30240
Description: Predicted to enable nucleic acid binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of U4/U6 x U5 tri-snRNP complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 27K; nucleic acid binding protein RY 1; nucleic acid-binding protein RY-1; putative nucleic acid binding protein RY-1; RY1; small nuclear ribonucleoprotein 27kDa (U4/U6.U5); small nuclear ribonucleoprotein, U4/U6.U5 27kDa subunit; U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein; U4/U6.U5 snRNP 27 kDa protein; U4/U6.U5 tri-snRNP-associated 27 kDa protein; U4/U6.U5 tri-snRNP-associated protein 3; U4/U6.U5-27K
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC402230  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38269,893,956 - 69,905,236 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl269,893,956 - 69,905,575 (+)Ensemblhg38GRCh38
GRCh37270,121,088 - 70,132,368 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36269,974,594 - 69,985,853 (+)NCBIBuild 36Build 36hg18NCBI36
Celera269,972,266 - 69,983,527 (+)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef269,857,032 - 69,868,320 (+)NCBIHuRef
CHM1_1270,050,725 - 70,062,018 (+)NCBICHM1_1
T2T-CHM13v2.0269,906,240 - 69,916,976 (+)NCBIT2T-CHM13v2.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2479028   PMID:7931148   PMID:9085842   PMID:12477932   PMID:15489334   PMID:15815621   PMID:16723661   PMID:17081983   PMID:17207965   PMID:17643375   PMID:19615732   PMID:20360068  
PMID:22365833   PMID:23602568   PMID:25416956   PMID:25693804   PMID:26186194   PMID:26344197   PMID:26496610   PMID:26752685   PMID:27129302   PMID:28514442   PMID:28561026   PMID:28878014  
PMID:29298432   PMID:29509190   PMID:29511261   PMID:30639242   PMID:30804502   PMID:30975767   PMID:31365120   PMID:31586073   PMID:31617661   PMID:32913203   PMID:33301849   PMID:33961781  
PMID:34133714   PMID:34373451   PMID:34535262   PMID:35013218   PMID:35944360   PMID:36244648   PMID:38113892   PMID:38697112  


Genomics

Comparative Map Data
SNRNP27
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38269,893,956 - 69,905,236 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl269,893,956 - 69,905,575 (+)Ensemblhg38GRCh38
GRCh37270,121,088 - 70,132,368 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36269,974,594 - 69,985,853 (+)NCBIBuild 36Build 36hg18NCBI36
Celera269,972,266 - 69,983,527 (+)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef269,857,032 - 69,868,320 (+)NCBIHuRef
CHM1_1270,050,725 - 70,062,018 (+)NCBICHM1_1
T2T-CHM13v2.0269,906,240 - 69,916,976 (+)NCBIT2T-CHM13v2.0
Snrnp27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,652,151 - 86,661,473 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl686,652,133 - 86,661,504 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38686,675,169 - 86,684,491 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl686,675,151 - 86,684,522 (-)Ensemblmm10GRCm38
MGSCv37686,625,163 - 86,634,485 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36686,640,803 - 86,650,125 (-)NCBIMGSCv36mm8
Celera688,612,797 - 88,622,344 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.75NCBI
Snrnp27
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84120,681,054 - 120,691,343 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4120,679,255 - 120,690,656 (-)EnsemblGRCr8
mRatBN7.24119,123,676 - 119,133,234 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4119,121,877 - 119,133,234 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4124,596,192 - 124,605,756 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04120,370,925 - 120,380,489 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04118,995,188 - 119,004,752 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04118,478,075 - 118,487,633 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4118,478,075 - 118,534,280 (-)Ensemblrn6Rnor6.0
Rnor_5.04183,048,089 - 183,057,647 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44120,828,680 - 120,838,238 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4108,093,738 - 108,103,296 (-)NCBICelera
RGSC_v3.14121,073,178 - 121,082,871 (-)NCBI
Cytogenetic Map4q34NCBI
Snrnp27
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542415,238,793 - 15,252,244 (-)Ensembl
ChiLan1.0NW_00495542415,243,190 - 15,251,831 (-)NCBIChiLan1.0ChiLan1.0
SNRNP27
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21256,505,707 - 56,517,088 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A56,510,222 - 56,521,034 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A69,936,640 - 69,947,971 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A71,054,108 - 71,065,343 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A71,054,108 - 71,065,343 (+)EnsemblpanPan2panpan1.1
SNRNP27
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11068,531,541 - 68,541,233 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1068,531,253 - 68,541,225 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1068,421,961 - 68,431,690 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01069,552,964 - 69,562,649 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1069,552,690 - 69,562,641 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11069,272,390 - 69,282,067 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01069,535,320 - 69,545,033 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01069,832,953 - 69,842,642 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Snrnp27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629214,452,473 - 14,465,211 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649114,106,066 - 14,118,856 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649114,106,124 - 14,118,823 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNRNP27
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl372,556,367 - 72,565,948 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1372,556,127 - 72,566,023 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2375,950,669 - 75,960,564 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SNRNP27
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11437,217,877 - 37,228,441 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1437,218,122 - 37,228,407 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604574,769,599 - 74,787,584 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snrnp27
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247623,490,190 - 3,503,566 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247623,494,301 - 3,503,456 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in SNRNP27
9 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2p16.1-11.2(chr2:58279519-83586962)x3 copy number gain See cases [RCV000136053] Chr2:58279519..83586962 [GRCh38]
Chr2:58506654..83814086 [GRCh37]
Chr2:58360158..83667597 [NCBI36]
Chr2:2p16.1-11.2		 pathogenic
GRCh38/hg38 2p16.3-11.2(chr2:47620388-86702722)x3 copy number gain See cases [RCV000137586] Chr2:47620388..86702722 [GRCh38]
Chr2:47847527..86929845 [GRCh37]
Chr2:47701031..86783356 [NCBI36]
Chr2:2p16.3-11.2		 uncertain significance
GRCh38/hg38 2p25.1-11.2(chr2:7495123-87705899)x3 copy number gain See cases [RCV000141494] Chr2:7495123..87705899 [GRCh38]
Chr2:7635254..88005418 [GRCh37]
Chr2:7552705..87786533 [NCBI36]
Chr2:2p25.1-11.2		 benign
GRCh37/hg19 2p13.3(chr2:70043280-70315412)x3 copy number gain Breast ductal adenocarcinoma [RCV000207070] Chr2:70043280..70315412 [GRCh37]
Chr2:2p13.3		 uncertain significance
GRCh37/hg19 2p15-11.2(chr2:62245236-86978895)x3 copy number gain See cases [RCV000448688] Chr2:62245236..86978895 [GRCh37]
Chr2:2p15-11.2		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
Single allele deletion not provided [RCV000714264] Chr2:40608411..146900718 [GRCh37]
Chr2:2p22.1-q22.3		 likely pathogenic
Single allele duplication not provided [RCV000677942] Chr2:63671346..85698002 [GRCh37]
Chr2:2p15-11.2		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p13.3(chr2:70122490-70125504)x0 copy number loss not provided [RCV000740481] Chr2:70122490..70125504 [GRCh37]
Chr2:2p13.3		 benign
GRCh37/hg19 2p13.3(chr2:70123564-70125504)x0 copy number loss not provided [RCV000740482] Chr2:70123564..70125504 [GRCh37]
Chr2:2p13.3		 benign
GRCh37/hg19 2p13.3(chr2:70123564-70128717)x0 copy number loss not provided [RCV000740483] Chr2:70123564..70128717 [GRCh37]
Chr2:2p13.3		 benign
GRCh37/hg19 2p13.3(chr2:70125092-70125504)x0 copy number loss not provided [RCV000740484] Chr2:70125092..70125504 [GRCh37]
Chr2:2p13.3		 benign
GRCh37/hg19 2p13.3(chr2:69506803-70159981)x1 copy number loss not provided [RCV001260153] Chr2:69506803..70159981 [GRCh37]
Chr2:2p13.3		 uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NC_000002.11:g.(?_69240632)_(74779761_?)dup duplication not provided [RCV003122858] Chr2:69240632..74779761 [GRCh37]
Chr2:2p13.3-13.1		 uncertain significance
Single allele duplication not specified [RCV002286373] Chr2:69512973..71153026 [GRCh38]
Chr2:2p13.3		 uncertain significance
GRCh37/hg19 2p25.1-q13(chr2:11504318-111365996)x1 copy number loss See cases [RCV002287563] Chr2:11504318..111365996 [GRCh37]
Chr2:2p25.1-q13		 pathogenic
NM_006857.3(SNRNP27):c.246G>C (p.Lys82Asn) single nucleotide variant not specified [RCV004193031] Chr2:69896526 [GRCh38]
Chr2:70123658 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_006857.3(SNRNP27):c.256C>T (p.Arg86Trp) single nucleotide variant not specified [RCV004098344] Chr2:69896536 [GRCh38]
Chr2:70123668 [GRCh37]
Chr2:2p13.3		 uncertain significance
GRCh37/hg19 2p14-13.3(chr2:65296579-71305638)x1 copy number loss not provided [RCV003223077] Chr2:65296579..71305638 [GRCh37]
Chr2:2p14-13.3		 uncertain significance
GRCh37/hg19 2p14-13.3(chr2:67702012-70506257)x1 copy number loss not specified [RCV003986387] Chr2:67702012..70506257 [GRCh37]
Chr2:2p14-13.3		 uncertain significance
NM_006857.3(SNRNP27):c.197G>A (p.Arg66Gln) single nucleotide variant not specified [RCV004462396] Chr2:69896477 [GRCh38]
Chr2:70123609 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_006857.3(SNRNP27):c.257G>A (p.Arg86Gln) single nucleotide variant not specified [RCV004462397] Chr2:69896537 [GRCh38]
Chr2:70123669 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_006857.3(SNRNP27):c.207A>T (p.Glu69Asp) single nucleotide variant not specified [RCV004670332] Chr2:69896487 [GRCh38]
Chr2:70123619 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_006857.3(SNRNP27):c.335T>C (p.Phe112Ser) single nucleotide variant not specified [RCV004670333] Chr2:69897443 [GRCh38]
Chr2:70124575 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_006857.3(SNRNP27):c.358G>A (p.Val120Met) single nucleotide variant not specified [RCV004865566] Chr2:69903190 [GRCh38]
Chr2:70130322 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_006857.3(SNRNP27):c.38G>A (p.Arg13His) single nucleotide variant not specified [RCV004864731] Chr2:69895097 [GRCh38]
Chr2:70122229 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_006857.3(SNRNP27):c.370G>A (p.Val124Ile) single nucleotide variant not specified [RCV005284819] Chr2:69903202 [GRCh38]
Chr2:70130334 [GRCh37]
Chr2:2p13.3		 uncertain significance
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1041
Count of miRNA genes:355
Interacting mature miRNAs:377
Transcripts:ENST00000244227, ENST00000409116, ENST00000450162, ENST00000487029, ENST00000488986
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597219157GWAS1315231_Hplatelet count QTL GWAS1315231 (human)7e-19platelet quantity (VT:0003179)platelet count (CMO:0000029)26990445269904453Human
597346069GWAS1442143_Hmonocyte measurement QTL GWAS1442143 (human)1e-09monocyte morphology trait (VT:0002620)26989767369897674Human

Markers in Region
RH67798  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,131,992 - 70,132,139UniSTSGRCh37
Build 36269,985,496 - 69,985,643RGDNCBI36
Celera269,983,170 - 69,983,317RGD
Cytogenetic Map2p13.3UniSTS
HuRef269,867,944 - 69,868,091UniSTS
GeneMap99-GB4 RH Map2218.68UniSTS
SHGC-12014  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,322,746 - 132,323,284UniSTSGRCh37
GRCh37270,131,509 - 70,131,716UniSTSGRCh37
Build 36269,985,013 - 69,985,220RGDNCBI36
Celera269,982,687 - 69,982,894RGD
Celera5128,452,767 - 128,453,305UniSTS
Cytogenetic Map2p13.3UniSTS
HuRef269,867,461 - 69,867,668UniSTS
HuRef5127,514,626 - 127,515,164UniSTS
Stanford-G3 RH Map23031.0UniSTS
GeneMap99-G3 RH Map22942.0UniSTS
RH70906  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,132,133 - 70,132,309UniSTSGRCh37
Build 36269,985,637 - 69,985,813RGDNCBI36
Celera269,983,311 - 69,983,487RGD
Cytogenetic Map2p13.3UniSTS
HuRef269,868,085 - 69,868,261UniSTS
GeneMap99-GB4 RH Map2218.27UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 174 1

Sequence


Ensembl Acc Id: ENST00000244227   ⟹   ENSP00000244227
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl269,893,956 - 69,905,236 (+)Ensembl
Ensembl Acc Id: ENST00000409116   ⟹   ENSP00000386608
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl269,893,959 - 69,905,218 (+)Ensembl
Ensembl Acc Id: ENST00000450162   ⟹   ENSP00000395144
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl269,893,964 - 69,904,671 (+)Ensembl
Ensembl Acc Id: ENST00000487029   ⟹   ENSP00000430449
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl269,904,254 - 69,905,575 (+)Ensembl
Ensembl Acc Id: ENST00000488986
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl269,896,520 - 69,903,407 (+)Ensembl
RefSeq Acc Id: NM_006857   ⟹   NP_006848
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38269,893,956 - 69,905,236 (+)NCBI
GRCh37270,121,075 - 70,132,368 (+)ENTREZGENE
Build 36269,974,594 - 69,985,853 (+)NCBI Archive
Celera269,972,266 - 69,983,527 (+)RGD
HuRef269,857,032 - 69,868,320 (+)ENTREZGENE
CHM1_1270,050,725 - 70,062,018 (+)NCBI
T2T-CHM13v2.0269,906,240 - 69,916,976 (+)NCBI
Sequence:
RefSeq Acc Id: NR_037862
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38269,893,956 - 69,905,236 (+)NCBI
GRCh37270,121,075 - 70,132,368 (+)ENTREZGENE
HuRef269,857,032 - 69,868,320 (+)ENTREZGENE
CHM1_1270,050,725 - 70,062,018 (+)NCBI
T2T-CHM13v2.0269,906,240 - 69,916,976 (+)NCBI
Sequence:
RefSeq Acc Id: NP_006848   ⟸   NM_006857
- UniProtKB: Q15410 (UniProtKB/Swiss-Prot),   Q8WVK2 (UniProtKB/Swiss-Prot),   A8K513 (UniProtKB/TrEMBL),   D6W5G1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000395144   ⟸   ENST00000450162
Ensembl Acc Id: ENSP00000244227   ⟸   ENST00000244227
Ensembl Acc Id: ENSP00000430449   ⟸   ENST00000487029
Ensembl Acc Id: ENSP00000386608   ⟸   ENST00000409116
Protein Domains
U4/U6.U5 small nuclear ribonucleoprotein 27kDa

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8WVK2-F1-model_v2 AlphaFold Q8WVK2 1-155 view protein structure

Promoters
RGD ID:6860572
Promoter ID:EPDNEW_H3451
Type:initiation region
Name:SNRNP27_1
Description:small nuclear ribonucleoprotein U4/U6.U5 subunit 27
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H3452  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38269,893,962 - 69,894,022EPDNEW
RGD ID:6860616
Promoter ID:EPDNEW_H3452
Type:initiation region
Name:SNRNP27_2
Description:small nuclear ribonucleoprotein U4/U6.U5 subunit 27
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H3451  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38269,904,534 - 69,904,594EPDNEW
RGD ID:6796601
Promoter ID:HG_KWN:33102
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000327369,   OTTHUMT00000327371,   UC002SFV.1,   UC002SFX.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36269,974,384 - 69,974,884 (+)MPROMDB
RGD ID:6811970
Promoter ID:HG_ACW:44525
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:RY1ANDMXD1.IAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 36269,982,981 - 69,983,481 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30240 AgrOrtholog
COSMIC SNRNP27 COSMIC
Ensembl Genes ENSG00000124380 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000244227 ENTREZGENE
  ENST00000244227.8 UniProtKB/Swiss-Prot
  ENST00000409116 ENTREZGENE
  ENST00000450162.6 UniProtKB/Swiss-Prot
GTEx ENSG00000124380 GTEx
HGNC ID HGNC:30240 ENTREZGENE
Human Proteome Map SNRNP27 Human Proteome Map
InterPro SNRNP27 UniProtKB/Swiss-Prot
KEGG Report hsa:11017 UniProtKB/Swiss-Prot
NCBI Gene 11017 ENTREZGENE
OMIM 619629 OMIM
PANTHER U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN UniProtKB/Swiss-Prot
  U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN UniProtKB/Swiss-Prot
Pfam SNRNP27 UniProtKB/Swiss-Prot
PharmGKB PA164726114 PharmGKB
UniProt A8K513 ENTREZGENE, UniProtKB/TrEMBL
  B8ZZ98_HUMAN UniProtKB/TrEMBL
  D6W5G1 ENTREZGENE
  H0YBW5_HUMAN UniProtKB/TrEMBL
  Q15410 ENTREZGENE
  Q8WVK2 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q15410 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 SNRNP27  small nuclear ribonucleoprotein U4/U6.U5 subunit 27    small nuclear ribonucleoprotein, U4/U6.U5 27kDa subunit  Symbol and/or name change 5135510 APPROVED
2015-11-10 SNRNP27  small nuclear ribonucleoprotein, U4/U6.U5 27kDa subunit    small nuclear ribonucleoprotein 27kDa (U4/U6.U5)  Symbol and/or name change 5135510 APPROVED