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Gene: TOMM20L (translocase of outer mitochondrial membrane 20 like) Homo sapiens

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Symbol:

TOMM20L

Name:

translocase of outer mitochondrial membrane 20 like

RGD ID:

1602627

HGNC Page

HGNC:33752

Description:

Predicted to enable mitochondrion targeting sequence binding activity. Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix and tRNA import into mitochondrion. Predicted to be located in mitochondrial outer membrane. Predicted to be part of mitochondrial outer membrane translocase complex.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

TOMM20-like protein 1; translocase of outer mitochondrial membrane 20 homolog (yeast)-like; translocase of outer mitochondrial membrane 20 homolog type I; translocase of outer mitochondrial membrane 20 homolog-like; UNQ9438

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

NCBI Annotation Information:

Note: July 18, 2008: Although this gene has been referred to as TIMM9, TIMM9 is a distinct locus, located in a head-head orientation to UNQ9438. [18 Jul 2008]

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	58,395,930 - 58,417,080 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	58,395,928 - 58,408,702 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	58,862,648 - 58,875,420 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	57,932,385 - 57,945,172 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	38,912,616 - 38,925,391 (+)	NCBI		Celera
Cytogenetic Map	14	q23.1	NCBI
HuRef	14	39,027,270 - 39,040,037 (+)	NCBI		HuRef
CHM1_1	14	58,801,207 - 58,813,988 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	52,602,950 - 52,624,123 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Joubert syndrome 23 (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3',4,4',5-Pentachlorobiphenyl (ISO)

aldehydo-D-glucose (ISO)

benzo[a]pyrene (EXP)

bisphenol A (ISO)

bisphenol F (ISO)

chlordecone (ISO)

D-glucose (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fructose (ISO)

glucose (ISO)

herbicide (ISO)

lead(0) (EXP)

methamphetamine (ISO)

tamoxifen (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular protein transport (IEA)

protein import into mitochondrial matrix (IBA)

protein targeting (IEA)

tRNA import into mitochondrion (IBA)

Cellular Component

membrane (IEA)

mitochondrial outer membrane (IEA)

mitochondrial outer membrane translocase complex (IBA,IEA)

mitochondrion (IEA)

Molecular Function

mitochondrion targeting sequence binding (IBA)

protein binding (IPI)

protein transmembrane transporter activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:12975309	PMID:15733919	PMID:21873635	PMID:26186194	PMID:28514442	PMID:29987050	PMID:32296183	PMID:33961781

Genomics

Comparative Map Data

TOMM20L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	58,395,930 - 58,417,080 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	58,395,928 - 58,408,702 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	58,862,648 - 58,875,420 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	57,932,385 - 57,945,172 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	38,912,616 - 38,925,391 (+)	NCBI		Celera
Cytogenetic Map	14	q23.1	NCBI
HuRef	14	39,027,270 - 39,040,037 (+)	NCBI		HuRef
CHM1_1	14	58,801,207 - 58,813,988 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	52,602,950 - 52,624,123 (+)	NCBI		T2T-CHM13v2.0

Tomm20l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	71,158,202 - 71,169,996 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	71,158,202 - 71,169,995 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	71,111,428 - 71,123,222 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	71,111,428 - 71,123,221 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	72,212,415 - 72,224,209 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
Celera	12	72,211,475 - 72,223,254 (+)	NCBI		Celera
Cytogenetic Map	12	C2	NCBI
cM Map	12	29.39	NCBI

Tomm20l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	95,335,681 - 95,346,116 (+)	NCBI		GRCr8
mRatBN7.2	6	89,594,016 - 89,612,070 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	89,599,873 - 89,610,147 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	6	93,538,377 - 93,549,533 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	93,539,271 - 93,651,154 (+)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	103,004,605 - 103,015,121 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	93,208,302 - 93,218,521 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	88,083,111 - 88,094,268 (+)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

TOMM20L
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	59,517,614 - 59,531,404 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	58,728,289 - 58,748,838 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	38,987,239 - 39,001,441 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	57,255,851 - 57,268,343 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	57,255,851 - 57,268,343 (+)	Ensembl	panpan1.1		panPan2

TOMM20L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	33,747,643 - 33,761,655 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	33,747,284 - 33,755,880 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	33,508,932 - 33,517,299 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	33,989,091 - 33,997,455 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	33,989,091 - 33,997,435 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	33,601,633 - 33,609,978 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	33,669,762 - 33,678,101 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	34,044,093 - 34,052,460 (+)	NCBI		UU_Cfam_GSD_1.0

Tomm20l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	71,392,612 - 71,412,432 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936495	2,779,851 - 2,786,233 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TOMM20L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	187,475,006 - 187,486,729 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	187,474,745 - 187,496,040 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	208,367,169 - 208,408,948 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TOMM20L
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	35,578,996 - 35,591,613 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	35,579,540 - 35,591,495 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	23,859,161 - 23,881,058 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in TOMM20L
15 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 14q22.3-23.3(chr14:57041036-67208231)x1	copy number loss	See cases [RCV000051521]	Chr14:57041036..67208231 [GRCh38] Chr14:57507754..67674948 [GRCh37] Chr14:56577507..66744701 [NCBI36] Chr14:14q22.3-23.3	pathogenic
GRCh38/hg38 14q23.1(chr14:58146022-61273619)x1	copy number loss	See cases [RCV000051522]	Chr14:58146022..61273619 [GRCh38] Chr14:58612740..61740337 [GRCh37] Chr14:57682493..60810090 [NCBI36] Chr14:14q23.1	pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3	copy number gain	See cases [RCV000135543]	Chr14:20151149..106855263 [GRCh38] Chr14:20619308..107263478 [GRCh37] Chr14:19689148..106334523 [NCBI36] Chr14:14q11.2-32.33	pathogenic
GRCh38/hg38 14q23.1-23.2(chr14:57653413-64093528)x1	copy number loss	See cases [RCV000138348]	Chr14:57653413..64093528 [GRCh38] Chr14:58120131..64560246 [GRCh37] Chr14:57189884..63629999 [NCBI36] Chr14:14q23.1-23.2	pathogenic
GRCh38/hg38 14q23.1(chr14:58288658-58509423)x1	copy number loss	See cases [RCV000143427]	Chr14:58288658..58509423 [GRCh38] Chr14:58755376..58976141 [GRCh37] Chr14:57825129..58045894 [NCBI36] Chr14:14q23.1	uncertain significance
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3	copy number gain	See cases [RCV000143373]	Chr14:20043514..106877229 [GRCh38] Chr14:20511673..107285437 [GRCh37] Chr14:19581513..106356482 [NCBI36] Chr14:14q11.2-32.33	pathogenic
GRCh37/hg19 14q23.1(chr14:58737402-58884615)x1	copy number loss	Thyroid hemiagenesis [RCV000488902]	Chr14:58737402..58884615 [GRCh37] Chr14:14q23.1	pathogenic\|likely pathogenic
GRCh37/hg19 14q23.1(chr14:58737402-58891576)x1	copy number loss	Thyroid hemiagenesis [RCV000488884]	Chr14:58737402..58891576 [GRCh37] Chr14:14q23.1	likely pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3	copy number gain	See cases [RCV000446256]	Chr14:19794561..107234280 [GRCh37] Chr14:14q11.2-32.33	pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437)	copy number gain	See cases [RCV000512041]	Chr14:20511673..107285437 [GRCh37] Chr14:14q11.2-32.33	pathogenic
NM_207377.3(TOMM20L):c.196A>G (p.Lys66Glu)	single nucleotide variant	not specified [RCV004303364]	Chr14:58402695 [GRCh38] Chr14:58869413 [GRCh37] Chr14:14q23.1	uncertain significance
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3	copy number gain	not provided [RCV000738412]	Chr14:19000422..107289053 [GRCh37] Chr14:14q11.1-32.33	pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3	copy number gain	not provided [RCV000738413]	Chr14:19280733..107287663 [GRCh37] Chr14:14q11.2-32.33	pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3	copy number gain	not provided [RCV000738414]	Chr14:19327823..107287663 [GRCh37] Chr14:14q11.2-32.33	pathogenic
GRCh37/hg19 14q23.1(chr14:58666970-59006831)x3	copy number gain	not provided [RCV000738498]	Chr14:58666970..59006831 [GRCh37] Chr14:14q23.1	benign
GRCh37/hg19 14q23.1(chr14:58668869-58927173)x3	copy number gain	not provided [RCV000738500]	Chr14:58668869..58927173 [GRCh37] Chr14:14q23.1	benign
GRCh37/hg19 14q23.1(chr14:58669403-59014522)x3	copy number gain	not provided [RCV000738501]	Chr14:58669403..59014522 [GRCh37] Chr14:14q23.1	benign
GRCh37/hg19 14q22.3-23.1(chr14:56605398-59404256)x1	copy number loss	not provided [RCV001006637]	Chr14:56605398..59404256 [GRCh37] Chr14:14q22.3-23.1	pathogenic
GRCh37/hg19 14q22.2-24.3(chr14:54654001-75828024)x3	copy number gain	14q22.2q24.3 duplication [RCV001506967]	Chr14:54654001..75828024 [GRCh37] Chr14:14q22.2-24.3	likely pathogenic
NC_000014.8:g.(?_58711639)_(59014694_?)del	deletion	Joubert syndrome 23 [RCV001949574]	Chr14:58711639..59014694 [GRCh37] Chr14:14q23.1	pathogenic
GRCh37/hg19 14q13.3-32.33(chr14:37671058-106985955)x2	copy number gain	See cases [RCV002286356]	Chr14:37671058..106985955 [GRCh37] Chr14:14q13.3-32.33	pathogenic
GRCh37/hg19 14q23.1(chr14:58833909-59109480)x3	copy number gain	not provided [RCV002474852]	Chr14:58833909..59109480 [GRCh37] Chr14:14q23.1	uncertain significance
GRCh37/hg19 14q22.3-23.2(chr14:57804997-63590203)x1	copy number loss	not provided [RCV002472446]	Chr14:57804997..63590203 [GRCh37] Chr14:14q22.3-23.2	likely pathogenic
NM_207377.3(TOMM20L):c.104G>A (p.Gly35Glu)	single nucleotide variant	not specified [RCV004207051]	Chr14:58396061 [GRCh38] Chr14:58862779 [GRCh37] Chr14:14q23.1	uncertain significance
NM_207377.3(TOMM20L):c.280A>T (p.Ile94Phe)	single nucleotide variant	not specified [RCV004110175]	Chr14:58407343 [GRCh38] Chr14:58874061 [GRCh37] Chr14:14q23.1	uncertain significance
NM_207377.3(TOMM20L):c.143G>A (p.Arg48Lys)	single nucleotide variant	not specified [RCV004133334]	Chr14:58396304 [GRCh38] Chr14:58863022 [GRCh37] Chr14:14q23.1	uncertain significance
NM_207377.3(TOMM20L):c.25C>G (p.Arg9Gly)	single nucleotide variant	not specified [RCV004131544]	Chr14:58395982 [GRCh38] Chr14:58862700 [GRCh37] Chr14:14q23.1	likely benign
NM_207377.3(TOMM20L):c.235C>T (p.Arg79Trp)	single nucleotide variant	not specified [RCV004215812]	Chr14:58402734 [GRCh38] Chr14:58869452 [GRCh37] Chr14:14q23.1	uncertain significance
NM_207377.3(TOMM20L):c.313G>A (p.Glu105Lys)	single nucleotide variant	not specified [RCV004183231]	Chr14:58407376 [GRCh38] Chr14:58874094 [GRCh37] Chr14:14q23.1	uncertain significance
NM_207377.3(TOMM20L):c.100C>G (p.Arg34Gly)	single nucleotide variant	not specified [RCV004122012]	Chr14:58396057 [GRCh38] Chr14:58862775 [GRCh37] Chr14:14q23.1	uncertain significance
GRCh37/hg19 14q22.3-23.1(chr14:57675327-59806898)x1	copy number loss	not provided [RCV003326901]	Chr14:57675327..59806898 [GRCh37] Chr14:14q22.3-23.1	uncertain significance
NM_207377.3(TOMM20L):c.451C>A (p.Pro151Thr)	single nucleotide variant	not specified [RCV004346650]	Chr14:58408574 [GRCh38] Chr14:58875292 [GRCh37] Chr14:14q23.1	uncertain significance
GRCh37/hg19 14q22.3-23.2(chr14:55667390-64447598)x1	copy number loss	not provided [RCV003483204]	Chr14:55667390..64447598 [GRCh37] Chr14:14q22.3-23.2	pathogenic
GRCh37/hg19 14q11.2-23.1(chr14:20511673-61826023)x3	copy number gain	not provided [RCV003485022]	Chr14:20511673..61826023 [GRCh37] Chr14:14q11.2-23.1	pathogenic
GRCh37/hg19 14q22.3-24.1(chr14:57588965-68334517)x3	copy number gain	not provided [RCV003485034]	Chr14:57588965..68334517 [GRCh37] Chr14:14q22.3-24.1	likely pathogenic
NM_012460.4(TIMM9):c.200T>G (p.Phe67Cys)	single nucleotide variant	not specified [RCV004469886]	Chr14:58409104 [GRCh38] Chr14:58875822 [GRCh37] Chr14:14q23.1	uncertain significance
NM_207377.3(TOMM20L):c.66C>G (p.Phe22Leu)	single nucleotide variant	not specified [RCV004467995]	Chr14:58396023 [GRCh38] Chr14:58862741 [GRCh37] Chr14:14q23.1	uncertain significance
NM_207377.3(TOMM20L):c.288C>A (p.His96Gln)	single nucleotide variant	not specified [RCV004687563]	Chr14:58407351 [GRCh38] Chr14:58874069 [GRCh37] Chr14:14q23.1	uncertain significance
NM_207377.3(TOMM20L):c.88A>G (p.Asn30Asp)	single nucleotide variant	not specified [RCV004682566]	Chr14:58396045 [GRCh38] Chr14:58862763 [GRCh37] Chr14:14q23.1	likely benign
NM_207377.3(TOMM20L):c.266A>C (p.Glu89Ala)	single nucleotide variant	not specified [RCV004682567]	Chr14:58407329 [GRCh38] Chr14:58874047 [GRCh37] Chr14:14q23.1	uncertain significance
NM_207377.3(TOMM20L):c.387A>T (p.Lys129Asn)	single nucleotide variant	not specified [RCV004682568]	Chr14:58407450 [GRCh38] Chr14:58874168 [GRCh37] Chr14:14q23.1	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	249
Count of miRNA genes:	202
Interacting mature miRNAs:	205
Transcripts:	ENST00000360945, ENST00000557754
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

RH46962

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	58,875,500 - 58,875,635	UniSTS	GRCh37
Build 36	14	57,945,253 - 57,945,388	RGD	NCBI36
Celera	14	38,925,472 - 38,925,607	RGD
Cytogenetic Map	14	q21	UniSTS
Cytogenetic Map	14	q23.1	UniSTS
HuRef	14	39,040,118 - 39,040,253	UniSTS
GeneMap99-GB4 RH Map	14	134.21	UniSTS
NCBI RH Map	14	593.7	UniSTS

RH44925

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	58,875,500 - 58,875,611	UniSTS	GRCh37
Build 36	14	57,945,253 - 57,945,364	RGD	NCBI36
Celera	14	38,925,472 - 38,925,583	RGD
Cytogenetic Map	14	q21	UniSTS
Cytogenetic Map	14	q23.1	UniSTS
HuRef	14	39,040,118 - 39,040,229	UniSTS
GeneMap99-GB4 RH Map	14	134.11	UniSTS
NCBI RH Map	14	626.5	UniSTS

RH78893

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	58,874,320 - 58,874,440	UniSTS	GRCh37
Build 36	14	57,944,073 - 57,944,193	RGD	NCBI36
Celera	14	38,924,292 - 38,924,412	RGD
Cytogenetic Map	14	q23.1	UniSTS
HuRef	14	39,038,938 - 39,039,058	UniSTS
GeneMap99-GB4 RH Map	14	134.11	UniSTS

RH66721

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	58,869,570 - 58,869,707	UniSTS	GRCh37
Build 36	14	57,939,323 - 57,939,460	RGD	NCBI36
Celera	14	38,919,542 - 38,919,679	RGD
Cytogenetic Map	14	q23.1	UniSTS
HuRef	14	39,034,197 - 39,034,334	UniSTS
GeneMap99-GB4 RH Map	14	137.13	UniSTS
NCBI RH Map	14	627.8	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system
1126	2286	2336	1768	4208	1576	2097	4	504	1502	353	2148	5816	5381	49	3045	1	799	1657	1483	164

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_207377	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011536742	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011536743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011536744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054376021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054376022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054376023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AL139021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY358266	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137557	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC144709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068264	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000360945 ⟹ ENSP00000354204

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	14	58,395,930 - 58,408,702 (+)	Ensembl

Ensembl Acc Id:

ENST00000557754 ⟹ ENSP00000451683

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	14	58,395,928 - 58,408,613 (+)	Ensembl

RefSeq Acc Id:

NM_207377 ⟹ NP_997260

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	14	58,395,930 - 58,408,702 (+)	NCBI
GRCh37	14	58,862,644 - 58,875,419 (+)	RGD
Build 36	14	57,932,385 - 57,945,172 (+)	NCBI Archive
Celera	14	38,912,616 - 38,925,391 (+)	RGD
HuRef	14	39,027,270 - 39,040,037 (+)	RGD
CHM1_1	14	58,801,207 - 58,813,988 (+)	NCBI
T2T-CHM13v2.0	14	52,602,950 - 52,615,753 (+)	NCBI

Sequence:

show sequence

GCTCGGCTTGTGGGACGCCCGCGGTCGGATGCCCTCCGTCCGCTCCCTCCTCCGCCTCTTGGCC
GCCGCGGCGGCCTGTGGCGCCTTCGCCTTCCTGGGCTATTGTATTTACCTCAACCGGAAGCGGC
GCGGGGACCCCGCGTTCAAGCGCCGCCTGCGGGACAAAAGAAGAGCAGAGCCTCAAAAGGCTGA
GGAGCAGGGCACGCAGTTGTGGGATCCAACGAAGAATAAAAAGTTGCAAGAACTTTTCTTGCAA
GAGGTACGGATGGGAGAACTTTGGTTATCTAGAGGAGAGCACAGAATGGGGATTCAACACCTCG
GCAATGCCCTTTTAGTGTGCGAGCAACCACGGGAACTTCTGAAAGTTTTCAAACACACTCTCCC
TCCCAAGGTATTTGAGATGCTGTTGCACAAAATTCCCCTTATTTGCCAGCAATTTGAGGCAGAC
ATGAATGAACAGGACTGCTTGGAGGATGATCCTGATTGAAAAACATTTCAACGTATCCACAGTC
CAGTGAGAATACTATGGTACCATACAGTATAAACAACTGCTCAGTGATATTTCCATTTATTTTA
CTTTGAGTAATAAAAATTTTTCTATCTCATA

hide sequence

RefSeq Acc Id:

XM_011536742 ⟹ XP_011535044

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	14	58,395,930 - 58,408,702 (+)	NCBI

Sequence:

show sequence

CTGCCGGCCGGCCCGCGCCCAACGCTCGGCTTGTGGGACGCCCGCGGTCGGATGCCCTCCGTCC
GCTCCCTCCTCCGCCTCTTGGCCGCCGCGGCGGCCTGTGGCGCCTTCGCCTTCCTGGGCTATTG
TATTTACCTCAACCGGAAGCGGCGCGGGGACCCCGCGTTCAAGCGCCGCCTGCGGGACAAAAGA
AGAGCAGAGCCTCAAAAGGCTGAGGAGCAGGGCACGCAGGTGCAGTGCTTTCGATCCGCACAGT
TGTGGGATCCAACGAAGAATAAAAAGTTGCAAGAACTTTTCTTGCAAGAGGTACGGATGGGAGA
ACTTTGGTTATCTAGAGGAGAGCACAGAATGGGGATTCAACACCTCGGCAATGCCCTTTTAGTG
TGCGAGCAACCACGGGAACTTCTGAAAGTTTTCAAACACACTCTCCCTCCCAAGGTATTTGAGA
TGCTGTTGCACAAAATTCCCCTTATTTGCCAGCAATTTGAGGCAGACATGAATGAACAGGACTG
CTTGGAGGATGATCCTGATTGAAAAACATTTCAACGTATCCACAGTCCAGTGAGAATACTATGG
TACCATACAGTATAAACAACTGCTCAGTGATATTTCCATTTATTTTACTTTGAGTAATAAAAAT
TTTTCTATCTCATA

hide sequence

RefSeq Acc Id:

XM_011536743 ⟹ XP_011535045

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	14	58,395,930 - 58,417,080 (+)	NCBI

Sequence:

show sequence

CCCCTGCCGGCCGGCCCGCGCCCAACGCTCGGCTTGTGGGACGCCCGCGGTCGGATGCCCTCCG
TCCGCTCCCTCCTCCGCCTCTTGGCCGCCGCGGCGGCCTGTGGCGCCTTCGCCTTCCTGGGCTA
TTGTATTTACCTCAACCGGAAGCGGCGCGGGGACCCCGCGTTCAAGCGCCGCCTGCGGGACAAA
AGAAGAGCAGAGCCTCAAAAGGCTGAGGAGCAGGGCACGCAGGTGCAGTGCTTTCGATCCGCAC
AGTTGTGGGATCCAACGAAGAATAAAAAGTTGCAAGAACTTTTCTTGCAAGAGGTACGGATGGG
AGAACTTTGGTTATCTAGAGGAGAGCACAGAATGGGGATTCAACACCTCGGCAATGCCCTTTTA
GTGTGCGAGCAACCACGGGAACTTCTGAAAGTTTTCAAACACACTCTCCCTCCCAAGGTATTTG
AGATGCTGTTGCACAAAATTCCCCTTATTTGCCAGTGAATAAGTCTCCCAAGATCTGACGGTTT
TATCAAGAG

hide sequence

RefSeq Acc Id:

XM_011536744 ⟹ XP_011535046

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	14	58,395,930 - 58,408,702 (+)	NCBI

Sequence:

show sequence

CCTGCCGGCCGGCCCGCGCCCAACGCTCGGCTTGTGGGACGCCCGCGGTCGGATGCCCTCCGTC
CGCTCCCTCCTCCGCCTCTTGGCCGCCGCGGCGGCCTGTGGCGCCTTCGCCTTCCTGGGCTATT
GTATTTACCTCAACCGGAAGCGGCGCGGGGACCCCGCGTTCAAGCGCCGCCTGCGGGACAGAGA
GCACAGAATGGGGATTCAACACCTCGGCAATGCCCTTTTAGTGTGCGAGCAACCACGGGAACTT
CTGAAAGTTTTCAAACACACTCTCCCTCCCAAGGTATTTGAGATGCTGTTGCACAAAATTCCCC
TTATTTGCCAGCAATTTGAGGCAGACATGAATGAACAGGACTGCTTGGAGGATGATCCTGATTG
AAAAACATTTCAACGTATCCACAGTCCAGTGAGAATACTATGGTACCATACAGTATAAACAACT
GCTCAGTGATATTTCCATTTATTTTACTTTGAGTAATAAAAATTTTTCTATCTCATA

hide sequence

RefSeq Acc Id:

XM_054376021 ⟹ XP_054231996

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	14	52,602,950 - 52,615,753 (+)	NCBI

RefSeq Acc Id:

XM_054376022 ⟹ XP_054231997

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	14	52,602,950 - 52,624,123 (+)	NCBI

RefSeq Acc Id:

XM_054376023 ⟹ XP_054231998

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	14	52,602,950 - 52,615,753 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_997260	(Get FASTA)	NCBI Sequence Viewer
	XP_011535044	(Get FASTA)	NCBI Sequence Viewer
	XP_011535045	(Get FASTA)	NCBI Sequence Viewer
	XP_011535046	(Get FASTA)	NCBI Sequence Viewer
	XP_054231996	(Get FASTA)	NCBI Sequence Viewer
	XP_054231997	(Get FASTA)	NCBI Sequence Viewer
	XP_054231998	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI37558	(Get FASTA)	NCBI Sequence Viewer
	AAI37564	(Get FASTA)	NCBI Sequence Viewer
	AAQ88633	(Get FASTA)	NCBI Sequence Viewer
	EAW80733	(Get FASTA)	NCBI Sequence Viewer
	EAW80734	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000354204
	ENSP00000354204.2
	ENSP00000451683.1
GenBank Protein	Q6UXN7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_997260 ⟸ NM_207377
- UniProtKB:	B2RPR0 (UniProtKB/Swiss-Prot), Q6UXN7 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MPSVRSLLRLLAAAAACGAFAFLGYCIYLNRKRRGDPAFKRRLRDKRRAEPQKAEEQGTQLWDP TKNKKLQELFLQEVRMGELWLSRGEHRMGIQHLGNALLVCEQPRELLKVFKHTLPPKVFEMLLH KIPLICQQFEADMNEQDCLEDDPD hide sequence

RefSeq Acc Id:	XP_011535045 ⟸ XM_011536743
- Peptide Label:	isoform X2
- Sequence:	show sequence MPSVRSLLRLLAAAAACGAFAFLGYCIYLNRKRRGDPAFKRRLRDKRRAEPQKAEEQGTQVQCF RSAQLWDPTKNKKLQELFLQEVRMGELWLSRGEHRMGIQHLGNALLVCEQPRELLKVFKHTLPP KVFEMLLHKIPLICQ hide sequence

RefSeq Acc Id:	XP_011535044 ⟸ XM_011536742
- Peptide Label:	isoform X1
- Sequence:	show sequence MPSVRSLLRLLAAAAACGAFAFLGYCIYLNRKRRGDPAFKRRLRDKRRAEPQKAEEQGTQVQCF RSAQLWDPTKNKKLQELFLQEVRMGELWLSRGEHRMGIQHLGNALLVCEQPRELLKVFKHTLPP KVFEMLLHKIPLICQQFEADMNEQDCLEDDPD hide sequence

RefSeq Acc Id:	XP_011535046 ⟸ XM_011536744
- Peptide Label:	isoform X3
- Sequence:	show sequence MPSVRSLLRLLAAAAACGAFAFLGYCIYLNRKRRGDPAFKRRLRDREHRMGIQHLGNALLVCEQ PRELLKVFKHTLPPKVFEMLLHKIPLICQQFEADMNEQDCLEDDPD hide sequence

Ensembl Acc Id:

ENSP00000451683 ⟸ ENST00000557754

Ensembl Acc Id:

ENSP00000354204 ⟸ ENST00000360945

RefSeq Acc Id:	XP_054231997 ⟸ XM_054376022
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_054231996 ⟸ XM_054376021
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_054231998 ⟸ XM_054376023
- Peptide Label:	isoform X3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6UXN7-F1-model_v2	AlphaFold	Q6UXN7	1-152	view protein structure

Promoters

RGD ID:

6791961

Promoter ID:

HG_KWN:19479

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, K562, Lymphoblastoid, NB4

Transcripts:

ENST00000360945

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	14	57,932,246 - 57,932,862 (+)	MPROMDB

RGD ID:

7227735

Promoter ID:

EPDNEW_H19614

Type:

initiation region

Name:

TOMM20L_1

Description:

translocase of outer mitochondrial membrane 20 like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	14	58,395,985 - 58,396,045	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:33752	AgrOrtholog
COSMIC	TOMM20L	COSMIC
Ensembl Genes	ENSG00000196860	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENST00000360945	ENTREZGENE
	ENST00000360945.7	UniProtKB/Swiss-Prot
	ENST00000557754.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.960.10	UniProtKB/Swiss-Prot
GTEx	ENSG00000196860	GTEx
HGNC ID	HGNC:33752	ENTREZGENE
Human Proteome Map	TOMM20L	Human Proteome Map
InterPro	MAS20	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MAS20_rcpt_metazoan	UniProtKB/Swiss-Prot
	Tom20_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	hsa:387990	UniProtKB/Swiss-Prot
NCBI Gene	387990	ENTREZGENE
PANTHER	PTHR12430	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TOMM20-LIKE PROTEIN 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	MAS20	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA162406689	PharmGKB
PIRSF	MAS20_rcpt	UniProtKB/Swiss-Prot
PRINTS	EUOM20RECPTR	UniProtKB/Swiss-Prot
	OM20RECEPTOR	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47157	UniProtKB/Swiss-Prot
UniProt	B2RPR0	ENTREZGENE
	G3V4A4_HUMAN	UniProtKB/TrEMBL
	Q6UXN7	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	B2RPR0	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-29	TOMM20L	translocase of outer mitochondrial membrane 20 like		translocase of outer mitochondrial membrane 20 homolog (yeast)-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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