CLEC3B (C-type lectin domain family 3 member B) - Rat Genome Database

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Gene: CLEC3B (C-type lectin domain family 3 member B) Homo sapiens
Analyze
Symbol: CLEC3B
Name: C-type lectin domain family 3 member B
RGD ID: 1602501
HGNC Page HGNC:11891
Description: Enables calcium ion binding activity; heparin binding activity; and kringle domain binding activity. Involved in bone mineralization. Located in cytoplasm; extracellular space; and granular component. Implicated in osteoarthritis and retinal macular dystrophy 4.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C-type lectin domain family 3, member B; DKFZp686H17246; MCDR4; plasminogen kringle 4-binding protein; tetranectin; tetranectin (plasminogen binding protein); tetranectin (plasminogen-binding protein); TN; TNA
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38345,026,303 - 45,036,071 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl345,001,548 - 45,036,071 (+)EnsemblGRCh38hg38GRCh38
GRCh37345,067,795 - 45,077,563 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36345,042,763 - 45,052,567 (+)NCBINCBI36Build 36hg18NCBI36
Celera345,005,711 - 45,015,514 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef345,111,173 - 45,120,977 (+)NCBIHuRef
CHM1_1345,017,739 - 45,027,543 (+)NCBICHM1_1
T2T-CHM13v2.0345,042,041 - 45,051,809 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Association study of candidate genes for the prevalence and progression of knee osteoarthritis. Valdes AM, etal., Arthritis Rheum. 2004 Aug;50(8):2497-507.
Additional References at PubMed
PMID:1354271   PMID:1511740   PMID:2298916   PMID:2533389   PMID:3009181   PMID:3427041   PMID:7589422   PMID:7798325   PMID:8418471   PMID:8889548   PMID:9154122   PMID:9256258  
PMID:9757090   PMID:9786936   PMID:10614823   PMID:10727405   PMID:10964919   PMID:11962752   PMID:12477932   PMID:12694198   PMID:14718574   PMID:15203218   PMID:15489334   PMID:15848710  
PMID:15901484   PMID:16453284   PMID:17353931   PMID:20551380   PMID:21832049   PMID:21873635   PMID:21900206   PMID:22261194   PMID:23376485   PMID:23533145   PMID:24927181   PMID:25846370  
PMID:26621497   PMID:27068509   PMID:27154906   PMID:28675934   PMID:28718365   PMID:28827734   PMID:30066941   PMID:30858459   PMID:31477130   PMID:31570938   PMID:32696821   PMID:34373451  
PMID:35500520   PMID:36380368   PMID:36607699   PMID:37310463  


Genomics

Comparative Map Data
CLEC3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38345,026,303 - 45,036,071 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl345,001,548 - 45,036,071 (+)EnsemblGRCh38hg38GRCh38
GRCh37345,067,795 - 45,077,563 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36345,042,763 - 45,052,567 (+)NCBINCBI36Build 36hg18NCBI36
Celera345,005,711 - 45,015,514 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef345,111,173 - 45,120,977 (+)NCBIHuRef
CHM1_1345,017,739 - 45,027,543 (+)NCBICHM1_1
T2T-CHM13v2.0345,042,041 - 45,051,809 (+)NCBIT2T-CHM13v2.0
Clec3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399122,980,011 - 122,986,497 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9122,980,011 - 122,986,497 (+)EnsemblGRCm39 Ensembl
GRCm389123,150,946 - 123,157,432 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9123,150,946 - 123,157,432 (+)EnsemblGRCm38mm10GRCm38
MGSCv379123,060,064 - 123,066,550 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369122,999,547 - 123,006,125 (+)NCBIMGSCv36mm8
Celera9123,602,080 - 123,608,547 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map973.91NCBI
Clec3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88131,687,575 - 131,693,292 (+)NCBIGRCr8
mRatBN7.28122,810,120 - 122,815,837 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8122,810,149 - 122,815,835 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8128,400,421 - 128,406,145 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08126,599,361 - 126,605,084 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08124,427,554 - 124,433,270 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08132,241,016 - 132,248,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8132,241,134 - 132,246,694 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08131,394,703 - 131,401,659 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8121,922,992 - 121,930,042 (+)NCBICelera
Cytogenetic Map8q32NCBI
Clec3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542026,665,472 - 26,669,474 (-)NCBIChiLan1.0ChiLan1.0
CLEC3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2244,984,162 - 44,994,010 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1344,989,026 - 44,998,777 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0344,927,098 - 44,936,847 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1346,038,115 - 46,047,927 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl346,038,115 - 46,047,927 (+)Ensemblpanpan1.1panPan2
CLEC3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12043,319,786 - 43,332,161 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2043,324,231 - 43,332,135 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2043,239,918 - 43,248,089 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02043,808,958 - 43,817,196 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2043,808,965 - 43,817,166 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12043,047,906 - 43,056,075 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02043,455,546 - 43,463,778 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02043,731,532 - 43,739,811 (-)NCBIUU_Cfam_GSD_1.0
Clec3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118198,378,987 - 198,386,451 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936695730,729 - 738,952 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936695731,184 - 738,752 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLEC3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1328,219,500 - 28,229,096 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11328,219,241 - 28,229,113 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21331,096,895 - 31,107,071 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CLEC3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1226,501,082 - 6,510,878 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl226,501,102 - 6,512,314 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041160,658,725 - 160,668,539 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clec3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473075,530,770 - 75,536,248 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473075,531,320 - 75,535,875 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CLEC3B
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh37/hg19 3p22.2-21.31(chr3:37028313-49929220)x3 copy number gain See cases [RCV000240519] Chr3:37028313..49929220 [GRCh37]
Chr3:3p22.2-21.31		 likely pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_003278.3(CLEC3B):c.604G>A (p.Val202Met) single nucleotide variant not specified [RCV004310788] Chr3:45035919 [GRCh38]
Chr3:45077411 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p24.3-21.31(chr3:16923595-45249923)x2,3 copy number gain not provided [RCV000682249] Chr3:16923595..45249923 [GRCh37]
Chr3:3p24.3-21.31		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p21.31(chr3:44444902-45413927)x1 copy number loss not provided [RCV001005429] Chr3:44444902..45413927 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.485C>T (p.Thr162Ile) single nucleotide variant not specified [RCV004326368] Chr3:45035800 [GRCh38]
Chr3:45077292 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.539C>A (p.Ala180Asp) single nucleotide variant Macular dystrophy, retinal, 4 [RCV002271318] Chr3:45035854 [GRCh38]
Chr3:45077346 [GRCh37]
Chr3:3p21.31		 pathogenic
GRCh37/hg19 3p21.31(chr3:44948482-49115809)x1 copy number loss not provided [RCV002279744] Chr3:44948482..49115809 [GRCh37]
Chr3:3p21.31		 pathogenic
NM_003278.3(CLEC3B):c.369G>C (p.Gln123His) single nucleotide variant not specified [RCV004109817] Chr3:45035684 [GRCh38]
Chr3:45077176 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.457G>T (p.Ala153Ser) single nucleotide variant not specified [RCV004144305] Chr3:45035772 [GRCh38]
Chr3:45077264 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.221G>A (p.Gly74Glu) single nucleotide variant not specified [RCV004221485] Chr3:45035536 [GRCh38]
Chr3:45077028 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.32G>A (p.Cys11Tyr) single nucleotide variant not specified [RCV004212890] Chr3:45026394 [GRCh38]
Chr3:45067886 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.64G>A (p.Glu22Lys) single nucleotide variant not specified [RCV004081445] Chr3:45026426 [GRCh38]
Chr3:45067918 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.421G>A (p.Glu141Lys) single nucleotide variant not specified [RCV004272192] Chr3:45035736 [GRCh38]
Chr3:45077228 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p21.31(chr3:44563378-45177006)x3 copy number gain not provided [RCV003484127] Chr3:44563378..45177006 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.388G>A (p.Glu130Lys) single nucleotide variant not specified [RCV004436981] Chr3:45035703 [GRCh38]
Chr3:45077195 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.373G>T (p.Val125Leu) single nucleotide variant not specified [RCV004436980] Chr3:45035688 [GRCh38]
Chr3:45077180 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_003278.3(CLEC3B):c.561G>C (p.Lys187Asn) single nucleotide variant not specified [RCV004612980] Chr3:45035876 [GRCh38]
Chr3:45077368 [GRCh37]
Chr3:3p21.31		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1197
Count of miRNA genes:530
Interacting mature miRNAs:599
Transcripts:ENST00000296130, ENST00000428034, ENST00000490386
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298487BFD1_HBody fluid distribution QTL 1 (human)3.94Body fluid distributionimpedance ratio33638071262380712Human
1298489RA4_HRheumatoid arthritis QTL 4 (human)0.0283Joint/bone inflammationrheumatoid arthritis33638071262380712Human
1643509BW293_HBody Weight QTL 293 (human)1.42Body weightBMI33638071262380712Human
2316061GLUCO194_HGlucose level QTL 194 (human)0.02Glucose level32338077449380774Human
2289308BW392_HBody weight QTL 392 (human)1.42Body weightBMI33638071262380712Human

Markers in Region
TNA_8680  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37345,077,036 - 45,077,763UniSTSGRCh37
Build 36345,052,040 - 45,052,767RGDNCBI36
Celera345,014,987 - 45,015,714RGD
HuRef345,120,450 - 45,121,177UniSTS
RH70861  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37345,077,260 - 45,077,415UniSTSGRCh37
Build 36345,052,264 - 45,052,419RGDNCBI36
Celera345,015,211 - 45,015,366RGD
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map3p22-p21.3UniSTS
HuRef345,120,674 - 45,120,829UniSTS
GeneMap99-GB4 RH Map3142.95UniSTS
SHGC-32929  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37345,067,858 - 45,067,959UniSTSGRCh37
Build 36345,042,862 - 45,042,963RGDNCBI36
Celera345,005,810 - 45,005,911RGD
Cytogenetic Map3p22-p21.3UniSTS
HuRef345,111,272 - 45,111,373UniSTS
GeneMap99-GB4 RH Map3149.14UniSTS
Whitehead-RH Map3174.5UniSTS
GeneMap99-G3 RH Map31843.0UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2408 2788 2234 4870 1714 2280 4 613 1593 455 2193 6920 6119 51 3708 837 1713 1558 170 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC104165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI826174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI826652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI837909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM669340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD616729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR541981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR542009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR749292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X70910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X70911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X70912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X98121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000296130   ⟹   ENSP00000296130
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl345,026,303 - 45,036,071 (+)Ensembl
Ensembl Acc Id: ENST00000428034   ⟹   ENSP00000396013
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl345,030,130 - 45,036,068 (+)Ensembl
Ensembl Acc Id: ENST00000490386
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl345,001,548 - 45,036,071 (+)Ensembl
RefSeq Acc Id: NM_001308394   ⟹   NP_001295323
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38345,030,143 - 45,036,071 (+)NCBI
CHM1_1345,021,602 - 45,027,545 (+)NCBI
T2T-CHM13v2.0345,045,881 - 45,051,809 (+)NCBI
Sequence:
RefSeq Acc Id: NM_003278   ⟹   NP_003269
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38345,026,303 - 45,036,071 (+)NCBI
GRCh37345,067,759 - 45,077,563 (+)ENTREZGENE
Build 36345,042,763 - 45,052,567 (+)NCBI Archive
HuRef345,111,173 - 45,120,977 (+)ENTREZGENE
CHM1_1345,017,739 - 45,027,543 (+)NCBI
T2T-CHM13v2.0345,042,041 - 45,051,809 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017007116   ⟹   XP_016862605
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38345,026,303 - 45,036,071 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054347707   ⟹   XP_054203682
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0345,042,041 - 45,051,809 (+)NCBI
RefSeq Acc Id: NP_003269   ⟸   NM_003278
- Peptide Label: isoform 1precursor
- UniProtKB: Q6FGX6 (UniProtKB/Swiss-Prot),   P05452 (UniProtKB/Swiss-Prot),   B2R582 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295323   ⟸   NM_001308394
- Peptide Label: isoform 2
- UniProtKB: E9PHK0 (UniProtKB/TrEMBL),   Q68DS3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016862605   ⟸   XM_017007116
- Peptide Label: isoform X1
- UniProtKB: B2R582 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000396013   ⟸   ENST00000428034
Ensembl Acc Id: ENSP00000296130   ⟸   ENST00000296130
RefSeq Acc Id: XP_054203682   ⟸   XM_054347707
- Peptide Label: isoform X1
- UniProtKB: B2R582 (UniProtKB/TrEMBL)
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05452-F1-model_v2 AlphaFold P05452 1-202 view protein structure

Promoters
RGD ID:6864152
Promoter ID:EPDNEW_H5241
Type:initiation region
Name:CLEC3B_1
Description:C-type lectin domain family 3 member B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5242  EPDNEW_H5243  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38345,026,306 - 45,026,366EPDNEW
RGD ID:6864154
Promoter ID:EPDNEW_H5242
Type:initiation region
Name:CLEC3B_3
Description:C-type lectin domain family 3 member B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5241  EPDNEW_H5243  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38345,030,148 - 45,030,208EPDNEW
RGD ID:6864156
Promoter ID:EPDNEW_H5243
Type:initiation region
Name:CLEC3B_2
Description:C-type lectin domain family 3 member B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5241  EPDNEW_H5242  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38345,034,841 - 45,034,901EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11891 AgrOrtholog
COSMIC CLEC3B COSMIC
Ensembl Genes ENSG00000163815 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000296130 ENTREZGENE
  ENST00000296130.5 UniProtKB/Swiss-Prot
  ENST00000428034 ENTREZGENE
  ENST00000428034.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000163815 GTEx
HGNC ID HGNC:11891 ENTREZGENE
Human Proteome Map CLEC3B Human Proteome Map
InterPro C-type_lectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CLec_Tetranectin-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:7123 UniProtKB/Swiss-Prot
NCBI Gene 7123 ENTREZGENE
OMIM 187520 OMIM
PANTHER TETRANECTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TETRANECTIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA36590 PharmGKB
PRINTS PNCREATITSAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE C_TYPE_LECTIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Triple coiled coil domain of C-type lectins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2R582 ENTREZGENE, UniProtKB/TrEMBL
  E9PHK0 ENTREZGENE, UniProtKB/TrEMBL
  P05452 ENTREZGENE
  Q68DS3 ENTREZGENE, UniProtKB/TrEMBL
  Q6FGX6 ENTREZGENE
  TETN_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q6FGX6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-22 CLEC3B  C-type lectin domain family 3 member B    C-type lectin domain family 3, member B  Symbol and/or name change 5135510 APPROVED