ZNF688 (zinc finger protein 688) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: ZNF688 (zinc finger protein 688) Homo sapiens
Analyze
Symbol: ZNF688
Name: zinc finger protein 688
RGD ID: 1602068
HGNC Page HGNC:30489
Description: Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,569,726 - 30,579,951 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,569,672 - 30,572,734 (-)EnsemblGRCh38hg38GRCh38
GRCh371630,581,047 - 30,583,728 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,488,508 - 30,491,229 (-)NCBINCBI36Build 36hg18NCBI36
Celera1629,714,682 - 29,717,403 (+)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1628,144,083 - 28,146,514 (-)NCBIHuRef
CHM1_11631,898,192 - 31,900,917 (-)NCBICHM1_1
T2T-CHM13v2.01630,956,705 - 30,967,326 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10493829   PMID:12477932   PMID:14702039   PMID:15489334   PMID:18976975   PMID:20562864   PMID:21873635   PMID:26871637   PMID:27503909   PMID:32296183   PMID:33961781  
PMID:34048709   PMID:34673265   PMID:35271311   PMID:35563538   PMID:37372979  


Genomics

Comparative Map Data
ZNF688
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,569,726 - 30,579,951 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,569,672 - 30,572,734 (-)EnsemblGRCh38hg38GRCh38
GRCh371630,581,047 - 30,583,728 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,488,508 - 30,491,229 (-)NCBINCBI36Build 36hg18NCBI36
Celera1629,714,682 - 29,717,403 (+)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1628,144,083 - 28,146,514 (-)NCBIHuRef
CHM1_11631,898,192 - 31,900,917 (-)NCBICHM1_1
T2T-CHM13v2.01630,956,705 - 30,967,326 (-)NCBIT2T-CHM13v2.0
Zfp688
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397127,018,138 - 127,023,786 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7127,018,139 - 127,021,240 (-)EnsemblGRCm39 Ensembl
GRCm387127,418,963 - 127,423,241 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,418,967 - 127,422,068 (-)EnsemblGRCm38mm10GRCm38
MGSCv377134,562,478 - 134,565,536 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367127,210,114 - 127,213,170 (-)NCBIMGSCv36mm8
Celera7127,264,862 - 127,267,920 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.51NCBI
Zfp688
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,469,858 - 191,473,527 (-)NCBIGRCr8
mRatBN7.21182,039,366 - 182,043,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,039,931 - 182,043,103 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01198,865,950 - 198,869,078 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,866,137 - 198,869,009 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,864,499 - 205,867,617 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,684,543 - 186,687,614 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1179,692,435 - 179,695,563 (-)NCBICelera
Cytogenetic Map1q37NCBI
Znf688
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554937,473,597 - 7,477,660 (-)NCBIChiLan1.0ChiLan1.0
ZNF688
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21833,775,842 - 33,780,066 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11638,577,257 - 38,581,271 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01624,395,172 - 24,399,056 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11630,940,633 - 30,944,454 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,940,633 - 30,944,454 (-)Ensemblpanpan1.1panPan2
ZNF688
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,576,983 - 17,580,040 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Znf688
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344124,899,008 - 124,901,714 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650112,996,085 - 12,999,248 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650112,996,868 - 12,999,713 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF688
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,792,182 - 17,795,425 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,791,430 - 17,795,431 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2318,155,699 - 18,242,524 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF688
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1527,254,104 - 27,272,735 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660682,229,471 - 2,233,383 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf688
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,712,953 - 13,718,758 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478213,715,787 - 13,719,264 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZNF688
19 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 16p12.2-11.2(chr16:23047969-30632245)x3 copy number gain See cases [RCV000052401] Chr16:23047969..30632245 [GRCh38]
Chr16:23059290..30643566 [GRCh37]
Chr16:22966791..30551067 [NCBI36]
Chr16:16p12.2-11.2		 pathogenic
GRCh38/hg38 16p11.2(chr16:30359229-30570499)x3 copy number gain See cases [RCV000053863] Chr16:30359229..30570499 [GRCh38]
Chr16:30370550..30581820 [GRCh37]
Chr16:30278051..30489321 [NCBI36]
Chr16:16p11.2		 uncertain significance
GRCh38/hg38 16p11.2(chr16:29909613-31438697)x3 copy number gain See cases [RCV000135339] Chr16:29909613..31438697 [GRCh38]
Chr16:29920934..31450018 [GRCh37]
Chr16:29828435..31357519 [NCBI36]
Chr16:16p11.2		 pathogenic
GRCh38/hg38 16p11.2(chr16:29581462-30691912)x1 copy number loss See cases [RCV000135589] Chr16:29581462..30691912 [GRCh38]
Chr16:29592783..30703233 [GRCh37]
Chr16:29500284..30610734 [NCBI36]
Chr16:16p11.2		 pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:27311746-31193406)x3 copy number gain See cases [RCV000140341] Chr16:27311746..31193406 [GRCh38]
Chr16:27323067..31204727 [GRCh37]
Chr16:27230568..31112228 [NCBI36]
Chr16:16p12.1-11.2		 pathogenic
GRCh38/hg38 16p12.2-11.2(chr16:23752047-31943755)x3 copy number gain See cases [RCV000141141] Chr16:23752047..31943755 [GRCh38]
Chr16:23763368..31955076 [GRCh37]
Chr16:23670869..31862577 [NCBI36]
Chr16:16p12.2-11.2		 pathogenic
GRCh37/hg19 16p11.2(chr16:30391304-31122666)x3 copy number gain Breast ductal adenocarcinoma [RCV000207028] Chr16:30391304..31122666 [GRCh37]
Chr16:16p11.2		 uncertain significance
GRCh37/hg19 16p13.3-11.2(chr16:1279324-31926800)x3 copy number gain Breast ductal adenocarcinoma [RCV000207053] Chr16:1279324..31926800 [GRCh37]
Chr16:16p13.3-11.2		 uncertain significance
Single allele deletion Branched-chain keto acid dehydrogenase kinase deficiency [RCV000735205] Chr16:30554158..31536880 [GRCh37]
Chr16:16p11.2		 uncertain significance
GRCh37/hg19 16p13.3-q24.3(chr16:69193-90274381)x3 copy number gain See cases [RCV000446684] Chr16:69193..90274381 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16p11.2(chr16:30515442-30792856)x1 copy number loss See cases [RCV000445894] Chr16:30515442..30792856 [GRCh37]
Chr16:16p11.2		 uncertain significance
GRCh37/hg19 16p11.2(chr16:28826162-29043901)x1 copy number loss See cases [RCV000448084] Chr16:28826162..29043901 [GRCh37]
Chr16:16p11.2		 likely pathogenic
GRCh37/hg19 16p13.2-q24.3(chr16:9273328-89548493)x3 copy number gain See cases [RCV000511622] Chr16:9273328..89548493 [GRCh37]
Chr16:16p13.2-q24.3		 uncertain significance
maternal UPD(16p) complex Hemimegalencephaly [RCV000494707] Chr16:1280042..33710558 [GRCh37]
Chr16:16p13.3-11.2		 pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062) copy number gain See cases [RCV000511296] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062)x3 copy number gain See cases [RCV000512138] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90163275)x3 copy number gain not provided [RCV000738917] Chr16:88165..90163275 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90274695)x3 copy number gain not provided [RCV000738918] Chr16:88165..90274695 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:61451-90294632)x3 copy number gain not provided [RCV000738915] Chr16:61451..90294632 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
NM_145271.4(ZNF688):c.488C>T (p.Thr163Ile) single nucleotide variant not specified [RCV004302439] Chr16:30570259 [GRCh38]
Chr16:30581580 [GRCh37]
Chr16:16p11.2		 uncertain significance
GRCh37/hg19 16p13.3-11.2(chr16:5805001-34230001) copy number gain Microcephaly [RCV001252948] Chr16:5805001..34230001 [GRCh37]
Chr16:16p13.3-11.2		 pathogenic
GRCh37/hg19 16p11.2(chr16:30350747-31905898)x3 copy number gain not provided [RCV001258619] Chr16:30350747..31905898 [GRCh37]
Chr16:16p11.2		 uncertain significance
GRCh37/hg19 16p11.2(chr16:29808153-30750270)x3 copy number gain Chromosome 16p11.2 duplication syndrome [RCV001801218] Chr16:29808153..30750270 [GRCh37]
Chr16:16p11.2		 pathogenic
GRCh37/hg19 16p11.2(chr16:29974415-30596982)x1 copy number loss Distal 16p11.2 microdeletion syndrome [RCV001801174] Chr16:29974415..30596982 [GRCh37]
Chr16:16p11.2		 likely pathogenic
GRCh37/hg19 16p11.2(chr16:30460206-30906733)x3 copy number gain not provided [RCV002475788] Chr16:30460206..30906733 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.461C>G (p.Pro154Arg) single nucleotide variant not specified [RCV004191512] Chr16:30570286 [GRCh38]
Chr16:30581607 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.43G>A (p.Glu15Lys) single nucleotide variant not specified [RCV004207695] Chr16:30571587 [GRCh38]
Chr16:30582908 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.544C>A (p.Arg182Ser) single nucleotide variant not specified [RCV004202695] Chr16:30570203 [GRCh38]
Chr16:30581524 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.26T>G (p.Leu9Arg) single nucleotide variant not specified [RCV004239616] Chr16:30571604 [GRCh38]
Chr16:30582925 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.305G>A (p.Arg102Gln) single nucleotide variant not specified [RCV004168110] Chr16:30571015 [GRCh38]
Chr16:30582336 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.14C>G (p.Pro5Arg) single nucleotide variant not specified [RCV004204586] Chr16:30571616 [GRCh38]
Chr16:30582937 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.643G>C (p.Glu215Gln) single nucleotide variant not specified [RCV004143153] Chr16:30570104 [GRCh38]
Chr16:30581425 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.59G>T (p.Cys20Phe) single nucleotide variant not specified [RCV004090342] Chr16:30571571 [GRCh38]
Chr16:30582892 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.776G>A (p.Arg259Gln) single nucleotide variant not specified [RCV004314969] Chr16:30569971 [GRCh38]
Chr16:30581292 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.406G>A (p.Val136Met) single nucleotide variant not specified [RCV004266991] Chr16:30570341 [GRCh38]
Chr16:30581662 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.246T>G (p.Ser82Arg) single nucleotide variant not specified [RCV004283286] Chr16:30571074 [GRCh38]
Chr16:30582395 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.140A>C (p.Gln47Pro) single nucleotide variant not specified [RCV004339907] Chr16:30571490 [GRCh38]
Chr16:30582811 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.440C>T (p.Ala147Val) single nucleotide variant not specified [RCV004490069] Chr16:30570307 [GRCh38]
Chr16:30581628 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.512T>C (p.Ile171Thr) single nucleotide variant not specified [RCV004490070] Chr16:30570235 [GRCh38]
Chr16:30581556 [GRCh37]
Chr16:16p11.2		 uncertain significance
NC_000016.9:g.(?_28889993)_(31202759_?)del deletion Dilated Cardiomyopathy, Dominant [RCV004582801] Chr16:28889993..31202759 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.239A>C (p.Gln80Pro) single nucleotide variant not specified [RCV004601730] Chr16:30571081 [GRCh38]
Chr16:30582402 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.244A>G (p.Ser82Gly) single nucleotide variant not specified [RCV004601732] Chr16:30571076 [GRCh38]
Chr16:30582397 [GRCh37]
Chr16:16p11.2		 uncertain significance
NM_145271.4(ZNF688):c.572G>A (p.Arg191His) single nucleotide variant not specified [RCV004601731] Chr16:30570175 [GRCh38]
Chr16:30581496 [GRCh37]
Chr16:16p11.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2149
Count of miRNA genes:796
Interacting mature miRNAs:943
Transcripts:ENST00000223459, ENST00000395219, ENST00000562455, ENST00000563276, ENST00000563665, ENST00000563707, ENST00000566632, ENST00000567855
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1204 2432 2788 2245 4942 1723 2345 4 622 1947 464 2268 7280 6453 52 3708 847 1731 1612 170

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001024683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005255139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005255140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024450165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024450166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047433653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047433654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054379679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054379680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054379681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054379682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC002310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC243616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF085979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM011208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ188280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF548148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU178870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU178871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU178872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000223459   ⟹   ENSP00000223459
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1630,569,726 - 30,571,714 (-)Ensembl
Ensembl Acc Id: ENST00000562455
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1630,570,178 - 30,571,527 (-)Ensembl
Ensembl Acc Id: ENST00000563276   ⟹   ENSP00000455227
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1630,569,672 - 30,572,734 (-)Ensembl
Ensembl Acc Id: ENST00000563665
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1630,569,686 - 30,571,672 (-)Ensembl
Ensembl Acc Id: ENST00000563707   ⟹   ENSP00000456070
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1630,570,899 - 30,571,635 (-)Ensembl
Ensembl Acc Id: ENST00000566632   ⟹   ENSP00000456047
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1630,570,220 - 30,571,320 (-)Ensembl
Ensembl Acc Id: ENST00000567855   ⟹   ENSP00000457222
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1630,570,734 - 30,571,652 (-)Ensembl
RefSeq Acc Id: NM_001024683   ⟹   NP_001019854
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381630,569,726 - 30,572,407 (-)NCBI
GRCh371630,580,998 - 30,585,243 (-)NCBI
Build 361630,488,508 - 30,491,229 (-)NCBI Archive
Celera1629,714,682 - 29,717,403 (+)RGD
HuRef1628,144,083 - 28,146,514 (-)RGD
CHM1_11631,898,192 - 31,900,917 (-)NCBI
T2T-CHM13v2.01630,956,705 - 30,959,386 (-)NCBI
Sequence:
RefSeq Acc Id: NM_145271   ⟹   NP_660314
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381630,569,726 - 30,571,714 (-)NCBI
GRCh371630,580,998 - 30,585,243 (-)NCBI
Build 361630,488,508 - 30,491,229 (-)NCBI Archive
Celera1629,714,682 - 29,717,403 (+)RGD
HuRef1628,144,083 - 28,146,514 (-)RGD
CHM1_11631,898,192 - 31,900,917 (-)NCBI
T2T-CHM13v2.01630,956,705 - 30,958,693 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005255139   ⟹   XP_005255196
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381630,569,726 - 30,571,427 (-)NCBI
GRCh371630,580,998 - 30,585,243 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005255140   ⟹   XP_005255197
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381630,569,726 - 30,571,427 (-)NCBI
GRCh371630,580,998 - 30,585,243 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047433653   ⟹   XP_047289609
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381630,569,726 - 30,571,714 (-)NCBI
RefSeq Acc Id: XM_047433654   ⟹   XP_047289610
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381630,569,726 - 30,579,951 (-)NCBI
RefSeq Acc Id: XM_054379679   ⟹   XP_054235654
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01630,956,705 - 30,967,326 (-)NCBI
RefSeq Acc Id: XM_054379680   ⟹   XP_054235655
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01630,956,705 - 30,966,931 (-)NCBI
RefSeq Acc Id: XM_054379681   ⟹   XP_054235656
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01630,956,705 - 30,966,931 (-)NCBI
RefSeq Acc Id: XM_054379682   ⟹   XP_054235657
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01630,957,432 - 30,966,931 (-)NCBI
RefSeq Acc Id: NP_660314   ⟸   NM_145271
- Peptide Label: isoform a
- UniProtKB: Q8WV14 (UniProtKB/Swiss-Prot),   Q8IW91 (UniProtKB/Swiss-Prot),   O75701 (UniProtKB/Swiss-Prot),   B3KV51 (UniProtKB/Swiss-Prot),   A8MV39 (UniProtKB/Swiss-Prot),   Q96MN0 (UniProtKB/Swiss-Prot),   P0C7X2 (UniProtKB/Swiss-Prot),   A0A0S2Z633 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001019854   ⟸   NM_001024683
- Peptide Label: isoform b
- UniProtKB: P0C7X2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005255197   ⟸   XM_005255140
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005255196   ⟸   XM_005255139
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSP00000455227   ⟸   ENST00000563276
Ensembl Acc Id: ENSP00000456070   ⟸   ENST00000563707
Ensembl Acc Id: ENSP00000223459   ⟸   ENST00000223459
Ensembl Acc Id: ENSP00000456047   ⟸   ENST00000566632
Ensembl Acc Id: ENSP00000457222   ⟸   ENST00000567855
RefSeq Acc Id: XP_047289610   ⟸   XM_047433654
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047289609   ⟸   XM_047433653
- Peptide Label: isoform X1
- UniProtKB: A0A0S2Z5X4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054235654   ⟸   XM_054379679
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054235656   ⟸   XM_054379681
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054235655   ⟸   XM_054379680
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054235657   ⟸   XM_054379682
- Peptide Label: isoform X6
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C7X2-F1-model_v2 AlphaFold P0C7X2 1-276 view protein structure

Promoters
RGD ID:6793642
Promoter ID:HG_KWN:23549
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001024683,   OTTHUMT00000255544
Position:
Human AssemblyChrPosition (strand)Source
Build 361630,490,266 - 30,492,297 (-)MPROMDB
RGD ID:7231997
Promoter ID:EPDNEW_H21744
Type:initiation region
Name:ZNF688_1
Description:zinc finger protein 688
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H21745  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381630,571,712 - 30,571,772EPDNEW
RGD ID:7231999
Promoter ID:EPDNEW_H21745
Type:initiation region
Name:ZNF688_2
Description:zinc finger protein 688
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H21744  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381630,572,156 - 30,572,216EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30489 AgrOrtholog
COSMIC ZNF688 COSMIC
Ensembl Genes ENSG00000229809 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000223459 ENTREZGENE
  ENST00000223459.11 UniProtKB/Swiss-Prot
  ENST00000563276 ENTREZGENE
  ENST00000563276.5 UniProtKB/Swiss-Prot
  ENST00000563707.1 UniProtKB/TrEMBL
  ENST00000566632.5 UniProtKB/TrEMBL
  ENST00000567855.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000229809 GTEx
HGNC ID HGNC:30489 ENTREZGENE
Human Proteome Map ZNF688 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Krueppel_C2H2_ZnF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:146542 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 146542 ENTREZGENE
PANTHER KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 688 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA142670487 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0S2Z5X4 ENTREZGENE, UniProtKB/TrEMBL
  A0A0S2Z633 ENTREZGENE, UniProtKB/TrEMBL
  A0A0S2Z6P0_HUMAN UniProtKB/TrEMBL
  A8MV39 ENTREZGENE
  B3KV51 ENTREZGENE
  H3BR26_HUMAN UniProtKB/TrEMBL
  H3BR45_HUMAN UniProtKB/TrEMBL
  H3BTK8_HUMAN UniProtKB/TrEMBL
  L0R5I2_HUMAN UniProtKB/TrEMBL
  O75701 ENTREZGENE
  P0C7X2 ENTREZGENE
  Q8IW91 ENTREZGENE
  Q8WV14 ENTREZGENE
  Q96MN0 ENTREZGENE
  ZN688_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A8MV39 UniProtKB/Swiss-Prot
  B3KV51 UniProtKB/Swiss-Prot
  O75701 UniProtKB/Swiss-Prot
  Q8IW91 UniProtKB/Swiss-Prot
  Q8WV14 UniProtKB/Swiss-Prot
  Q96MN0 UniProtKB/Swiss-Prot