RBM42 (RNA binding motif protein 42) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: RBM42 (RNA binding motif protein 42) Homo sapiens
Analyze
Symbol: RBM42
Name: RNA binding motif protein 42
RGD ID: 1601847
HGNC Page HGNC:28117
Description: Enables RNA binding activity. Predicted to act upstream of or within negative regulation of mRNA splicing, via spliceosome. Part of U4/U6 x U5 tri-snRNP complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC10433; RNA-binding motif protein 42; RNA-binding protein 42
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,629,036 - 35,637,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,629,030 - 35,637,686 (+)EnsemblGRCh38hg38GRCh38
GRCh371936,119,938 - 36,128,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,811,820 - 40,820,427 (+)NCBINCBI36Build 36hg18NCBI36
Celera1932,833,444 - 32,842,052 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,625,223 - 32,633,832 (+)NCBIHuRef
CHM1_11936,121,512 - 36,130,119 (+)NCBICHM1_1
T2T-CHM13v2.01938,173,991 - 38,182,639 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
mRNA binding  (IBA,IEA)
protein binding  (IPI)
RNA binding  (HDA,IEA)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Dystonia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:16189514   PMID:16713569   PMID:19170760   PMID:19615732   PMID:21145461   PMID:21244100   PMID:21832049   PMID:21873635   PMID:22174317   PMID:22365833  
PMID:22658674   PMID:22939629   PMID:23437009   PMID:24163370   PMID:25416956   PMID:25921289   PMID:26186194   PMID:26344197   PMID:28514442   PMID:28561026   PMID:28695742   PMID:29298432  
PMID:29509190   PMID:29802200   PMID:29892012   PMID:30209976   PMID:30804394   PMID:30804502   PMID:30884312   PMID:30975767   PMID:31076518   PMID:31091453   PMID:31343991   PMID:31527615  
PMID:31586073   PMID:31822558   PMID:32296183   PMID:32513696   PMID:32807901   PMID:32994395   PMID:33306668   PMID:33961781   PMID:34133714   PMID:34709727   PMID:35013218   PMID:35241646  
PMID:35271311   PMID:35575683   PMID:35944360   PMID:35945219   PMID:36215168   PMID:36244648   PMID:37294900   PMID:37689310   PMID:37827155   PMID:38113892   PMID:38334954   PMID:38360978  
PMID:38697112  


Genomics

Comparative Map Data
RBM42
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,629,036 - 35,637,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,629,030 - 35,637,686 (+)EnsemblGRCh38hg38GRCh38
GRCh371936,119,938 - 36,128,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,811,820 - 40,820,427 (+)NCBINCBI36Build 36hg18NCBI36
Celera1932,833,444 - 32,842,052 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,625,223 - 32,633,832 (+)NCBIHuRef
CHM1_11936,121,512 - 36,130,119 (+)NCBICHM1_1
T2T-CHM13v2.01938,173,991 - 38,182,639 (+)NCBIT2T-CHM13v2.0
Rbm42
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,340,420 - 30,349,653 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,340,424 - 30,349,742 (-)EnsemblGRCm39 Ensembl
GRCm38730,640,995 - 30,650,228 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,640,999 - 30,650,317 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,426,014 - 31,435,247 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36730,349,761 - 30,358,925 (-)NCBIMGSCv36mm8
Celera725,232,827 - 25,242,063 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map718.95NCBI
Rbm42
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,026,050 - 95,036,020 (-)NCBIGRCr8
mRatBN7.2185,898,618 - 85,908,569 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,898,625 - 85,908,573 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx191,314,846 - 91,324,699 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0199,781,017 - 99,790,871 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,073,133 - 93,082,985 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,099,296 - 89,109,248 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,099,277 - 89,109,230 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,254,914 - 90,264,857 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,692,754 - 85,702,684 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1185,770,869 - 85,780,753 (-)NCBI
Celera180,270,333 - 80,280,263 (-)NCBICelera
Cytogenetic Map1q21NCBI
Rbm42
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554684,844,747 - 4,854,504 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554684,844,780 - 4,854,261 (+)NCBIChiLan1.0ChiLan1.0
RBM42
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,625,564 - 41,634,271 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,609,051 - 43,617,721 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,559,215 - 32,567,899 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,295,079 - 41,303,817 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,294,818 - 41,303,817 (+)Ensemblpanpan1.1panPan2
RBM42
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,978,132 - 116,985,845 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,971,365 - 116,985,796 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,383,343 - 116,391,065 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01117,581,376 - 117,589,098 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,581,172 - 117,589,073 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,144,359 - 117,152,078 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,768,265 - 116,775,987 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,824,179 - 117,831,897 (-)NCBIUU_Cfam_GSD_1.0
Rbm42
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,960,493 - 10,969,107 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936570676,537 - 685,419 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936570676,775 - 685,415 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBM42
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl645,074,540 - 45,083,239 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1645,074,527 - 45,083,124 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,531,490 - 40,540,418 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RBM42
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,539,718 - 30,548,412 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,539,721 - 30,548,414 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660738,335,012 - 8,343,699 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbm42
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247947,991,462 - 8,000,804 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247947,991,685 - 8,000,314 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RBM42
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31
pathogenic
GRCh38/hg38 19q12-13.13(chr19:29661858-38114723)x1 copy number loss See cases [RCV000135879] Chr19:29661858..38114723 [GRCh38]
Chr19:30152765..38605363 [GRCh37]
Chr19:34844605..43297203 [NCBI36]
Chr19:19q12-13.13
pathogenic
GRCh38/hg38 19q12-13.13(chr19:29671324-37902990)x1 copy number loss See cases [RCV000136794] Chr19:29671324..37902990 [GRCh38]
Chr19:30162231..38393630 [GRCh37]
Chr19:34854071..43085470 [NCBI36]
Chr19:19q12-13.13
pathogenic
GRCh37/hg19 19q13.12(chr19:35723176-36183886)x3 copy number gain See cases [RCV000448697] Chr19:35723176..36183886 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19q12-13.12(chr19:30735448-36120396)x3 copy number gain See cases [RCV000448231] Chr19:30735448..36120396 [GRCh37]
Chr19:19q12-13.12
pathogenic
NM_024321.5(RBM42):c.791C>T (p.Ala264Val) single nucleotide variant not specified [RCV004306395] Chr19:35633793 [GRCh38]
Chr19:36124695 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic|uncertain significance
NM_024321.5(RBM42):c.802G>A (p.Val268Met) single nucleotide variant not specified [RCV004299611] Chr19:35633804 [GRCh38]
Chr19:36124706 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
Single allele deletion Dystonic disorder [RCV001003865] Chr19:35553425..36264299 [GRCh37]
Chr19:19q13.12
pathogenic
GRCh37/hg19 19q13.12(chr19:35658728-36173537)x3 copy number gain not provided [RCV000752672] Chr19:35658728..36173537 [GRCh37]
Chr19:19q13.12
benign
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19q13.11-13.12(chr19:35111811-37744992) copy number loss Generalized epilepsy with febrile seizures plus, type 1 [RCV000767768] Chr19:35111811..37744992 [GRCh37]
Chr19:19q13.11-13.12
pathogenic
GRCh37/hg19 19q13.11-13.12(chr19:35043556-36316644) copy number loss not provided [RCV000767769] Chr19:35043556..36316644 [GRCh37]
Chr19:19q13.11-13.12
pathogenic
GRCh37/hg19 19q13.12(chr19:35613953-36183886)x1 copy number loss not provided [RCV000845987] Chr19:35613953..36183886 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19q11-13.33(chr19:28271106-49213832)x3 copy number gain not provided [RCV000845733] Chr19:28271106..49213832 [GRCh37]
Chr19:19q11-13.33
pathogenic
NC_000019.9:g.(?_33167170)_(36643309_?)dup duplication Hereditary spastic paraplegia 75 [RCV003107659] Chr19:33167170..36643309 [GRCh37]
Chr19:19q13.11-13.12
uncertain significance
GRCh37/hg19 19p13.11-q13.2(chr19:19546923-41313229)x3 copy number gain Specific learning disability [RCV001801194] Chr19:19546923..41313229 [GRCh37]
Chr19:19p13.11-q13.2
pathogenic
NC_000019.9:g.(?_35521725)_(36643309_?)del deletion Brugada syndrome 5 [RCV001910265] Chr19:35521725..36643309 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19q13.12(chr19:36019064-36516110)x3 copy number gain not provided [RCV001833065] Chr19:36019064..36516110 [GRCh37]
Chr19:19q13.12
uncertain significance
NC_000019.9:g.(?_35521725)_(36229458_?)del deletion not provided [RCV001975081] Chr19:35521725..36229458 [GRCh37]
Chr19:19q13.12
pathogenic
NM_024321.5(RBM42):c.416G>A (p.Arg139Gln) single nucleotide variant not specified [RCV004333652] Chr19:35631379 [GRCh38]
Chr19:36122281 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.718G>C (p.Gly240Arg) single nucleotide variant not specified [RCV004240308] Chr19:35633720 [GRCh38]
Chr19:36124622 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.215T>A (p.Val72Glu) single nucleotide variant not specified [RCV004228859] Chr19:35629606 [GRCh38]
Chr19:36120508 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.983G>A (p.Arg328Gln) single nucleotide variant not specified [RCV004235686] Chr19:35633985 [GRCh38]
Chr19:36124887 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.884C>T (p.Pro295Leu) single nucleotide variant not specified [RCV004213815] Chr19:35633886 [GRCh38]
Chr19:36124788 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.649C>A (p.Pro217Thr) single nucleotide variant not specified [RCV004124606] Chr19:35633217 [GRCh38]
Chr19:36124119 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.1165G>A (p.Gly389Ser) single nucleotide variant not specified [RCV004179330] Chr19:35637187 [GRCh38]
Chr19:36128089 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.1030C>A (p.Leu344Met) single nucleotide variant not specified [RCV004225475] Chr19:35634268 [GRCh38]
Chr19:36125170 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.764C>T (p.Ala255Val) single nucleotide variant not specified [RCV004170924] Chr19:35633766 [GRCh38]
Chr19:36124668 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.337A>G (p.Met113Val) single nucleotide variant not specified [RCV004260206] Chr19:35631194 [GRCh38]
Chr19:36122096 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.541C>T (p.Arg181Cys) single nucleotide variant not specified [RCV004276609] Chr19:35633109 [GRCh38]
Chr19:36124011 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.1012C>G (p.Leu338Val) single nucleotide variant not specified [RCV004313380] Chr19:35634014 [GRCh38]
Chr19:36124916 [GRCh37]
Chr19:19q13.12
uncertain significance
Single allele deletion not provided [RCV003448708] Chr19:35225414..37357598 [GRCh37]
Chr19:19q13.11-13.12
pathogenic
GRCh37/hg19 19q11-13.2(chr19:28271146-41508851)x3 copy number gain not specified [RCV003986115] Chr19:28271146..41508851 [GRCh37]
Chr19:19q11-13.2
pathogenic
NM_024321.5(RBM42):c.1279G>A (p.Val427Ile) single nucleotide variant not specified [RCV004441298] Chr19:35637301 [GRCh38]
Chr19:36128203 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.535G>A (p.Gly179Ser) single nucleotide variant not specified [RCV004441302] Chr19:35633103 [GRCh38]
Chr19:36124005 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.541C>A (p.Arg181Ser) single nucleotide variant not specified [RCV004441303] Chr19:35633109 [GRCh38]
Chr19:36124011 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.635G>A (p.Arg212Gln) single nucleotide variant not specified [RCV004441304] Chr19:35633203 [GRCh38]
Chr19:36124105 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.1198G>A (p.Ala400Thr) single nucleotide variant not specified [RCV004441297] Chr19:35637220 [GRCh38]
Chr19:36128122 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.32C>T (p.Pro11Leu) single nucleotide variant not specified [RCV004441299] Chr19:35629185 [GRCh38]
Chr19:36120087 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.402C>G (p.Asp134Glu) single nucleotide variant not specified [RCV004441300] Chr19:35631365 [GRCh38]
Chr19:36122267 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.517C>G (p.Leu173Val) single nucleotide variant not specified [RCV004441301] Chr19:35633085 [GRCh38]
Chr19:36123987 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19q13.11-13.12(chr19:35223021-36895699)x1 copy number loss not provided [RCV004577477] Chr19:35223021..36895699 [GRCh37]
Chr19:19q13.11-13.12
pathogenic
NM_024321.5(RBM42):c.473G>A (p.Arg158His) single nucleotide variant not specified [RCV004660855] Chr19:35632966 [GRCh38]
Chr19:36123868 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.761C>T (p.Ala254Val) single nucleotide variant not specified [RCV004660854] Chr19:35633763 [GRCh38]
Chr19:36124665 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_024321.5(RBM42):c.544C>A (p.Pro182Thr) single nucleotide variant not specified [RCV004671716] Chr19:35633112 [GRCh38]
Chr19:36124014 [GRCh37]
Chr19:19q13.12
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2988
Count of miRNA genes:515
Interacting mature miRNAs:554
Transcripts:ENST00000262633, ENST00000360475, ENST00000586618, ENST00000588161, ENST00000589559, ENST00000589871, ENST00000592202, ENST00000592526
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
1300034BP50_HBlood pressure QTL 50 (human)2.10.00094Blood pressuresystolic191108946337089463Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence


Ensembl Acc Id: ENST00000262633   ⟹   ENSP00000262633
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1935,629,036 - 35,637,685 (+)Ensembl
Ensembl Acc Id: ENST00000586618   ⟹   ENSP00000466548
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1935,629,068 - 35,637,684 (+)Ensembl
Ensembl Acc Id: ENST00000588161   ⟹   ENSP00000466044
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1935,629,030 - 35,637,686 (+)Ensembl
Ensembl Acc Id: ENST00000589559   ⟹   ENSP00000468060
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1935,629,077 - 35,637,644 (+)Ensembl
Ensembl Acc Id: ENST00000589871   ⟹   ENSP00000467278
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1935,629,131 - 35,637,641 (+)Ensembl
Ensembl Acc Id: ENST00000592202   ⟹   ENSP00000467614
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1935,629,067 - 35,637,655 (+)Ensembl
Ensembl Acc Id: ENST00000592526
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1935,629,091 - 35,631,912 (+)Ensembl
RefSeq Acc Id: NM_001319113   ⟹   NP_001306042
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381935,629,036 - 35,637,685 (+)NCBI
CHM1_11936,121,450 - 36,130,120 (+)NCBI
T2T-CHM13v2.01938,173,991 - 38,182,639 (+)NCBI
Sequence:
RefSeq Acc Id: NM_024321   ⟹   NP_077297
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381935,629,036 - 35,637,685 (+)NCBI
GRCh371936,119,980 - 36,128,587 (+)RGD
Build 361940,811,820 - 40,820,427 (+)NCBI Archive
Celera1932,833,444 - 32,842,052 (+)RGD
HuRef1932,625,223 - 32,633,832 (+)RGD
CHM1_11936,121,450 - 36,130,120 (+)NCBI
T2T-CHM13v2.01938,173,991 - 38,182,639 (+)NCBI
Sequence:
RefSeq Acc Id: NP_077297   ⟸   NM_024321
- Peptide Label: isoform 1
- UniProtKB: Q8N5R7 (UniProtKB/Swiss-Prot),   O00320 (UniProtKB/Swiss-Prot),   Q9BU66 (UniProtKB/Swiss-Prot),   Q9BTD8 (UniProtKB/Swiss-Prot),   K7EP90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001306042   ⟸   NM_001319113
- Peptide Label: isoform 2
- UniProtKB: K7EP90 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000466548   ⟸   ENST00000586618
Ensembl Acc Id: ENSP00000466044   ⟸   ENST00000588161
Ensembl Acc Id: ENSP00000468060   ⟸   ENST00000589559
Ensembl Acc Id: ENSP00000467278   ⟸   ENST00000589871
Ensembl Acc Id: ENSP00000262633   ⟸   ENST00000262633
Ensembl Acc Id: ENSP00000467614   ⟸   ENST00000592202
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9BTD8-F1-model_v2 AlphaFold Q9BTD8 1-480 view protein structure

Promoters
RGD ID:7239545
Promoter ID:EPDNEW_H25519
Type:initiation region
Name:RBM42_1
Description:RNA binding motif protein 42
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381935,629,036 - 35,629,096EPDNEW
RGD ID:6795978
Promoter ID:HG_KWN:29667
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_024321,   UC002OAO.1,   UC002OAP.1,   UC002OAQ.1,   UC010EEF.1,   UC010EEG.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361940,811,399 - 40,811,899 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:28117 AgrOrtholog
COSMIC RBM42 COSMIC
Ensembl Genes ENSG00000126254 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000262633 ENTREZGENE
  ENST00000262633.9 UniProtKB/Swiss-Prot
  ENST00000586618.5 UniProtKB/TrEMBL
  ENST00000588161 ENTREZGENE
  ENST00000588161.5 UniProtKB/Swiss-Prot
  ENST00000589559.5 UniProtKB/TrEMBL
  ENST00000589871.1 UniProtKB/TrEMBL
  ENST00000592202.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000126254 GTEx
HGNC ID HGNC:28117 ENTREZGENE
Human Proteome Map RBM42 Human Proteome Map
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBM42_RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM-Poly(A)_Binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:79171 UniProtKB/Swiss-Prot
NCBI Gene 79171 ENTREZGENE
OMIM 613232 OMIM
PANTHER RNA-BINDING PROTEIN 42 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162400760 PharmGKB
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt K7EML2_HUMAN UniProtKB/TrEMBL
  K7EP90 ENTREZGENE, UniProtKB/TrEMBL
  K7EQ03_HUMAN UniProtKB/TrEMBL
  K7ER08_HUMAN UniProtKB/TrEMBL
  O00320 ENTREZGENE
  Q8N5R7 ENTREZGENE
  Q9BTD8 ENTREZGENE
  Q9BU66 ENTREZGENE
  RBM42_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary O00320 UniProtKB/Swiss-Prot
  Q8N5R7 UniProtKB/Swiss-Prot
  Q9BU66 UniProtKB/Swiss-Prot