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Gene: Acyp2 (acylphosphatase 2) Rattus norvegicus

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Symbol:

Acyp2

Name:

acylphosphatase 2

RGD ID:

1595836

Description:

Predicted to enable acylphosphatase activity and identical protein binding activity. Predicted to be located in mitochondrion. Orthologous to human ACYP2 (acylphosphatase 2); PARTICIPATES IN pyruvate metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; acetamide; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

acylphosphatase 2, muscle type; acylphosphatase, muscle type isozyme; acylphosphatase-2; acylphosphatase-2-like; acylphosphate phosphohydrolase 2; LOC100361559; LOC364224; LOC682245; similar to Acylphosphatase, muscle type isozyme (Acylphosphate phosphohydrolase)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACYP2 (acylphosphatase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB
Mus musculus (house mouse):	Acyp2 (acylphosphatase 2, muscle type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Acyp2 (acylphosphatase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACYP2 (acylphosphatase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACYP2 (acylphosphatase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Acyp2 (acylphosphatase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACYP2 (acylphosphatase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACYP2 (acylphosphatase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Acyp2 (acylphosphatase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MRPL42 (mitochondrial ribosomal protein L42)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ACYP2 (acylphosphatase 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Homo sapiens (human):	ACYP2 (acylphosphatase 2)	Alliance	DIOPT (HGNC\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Acyp2 (acylphosphatase 2, muscle type)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	acyp2 (acylphosphatase 2, muscle type)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Acyp	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG11052	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11052	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	acyp2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	acyp2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	108,402,837 - 108,572,367 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	108,402,544 - 108,633,318 (-)	Ensembl				GRCr8
mRatBN7.2	14	104,201,894 - 104,371,415 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	104,201,895 - 104,371,386 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	108,520,531 - 108,708,220 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	109,768,265 - 109,947,510 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	106,240,692 - 106,419,940 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	114,891,245 - 115,052,497 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	114,891,246 - 115,052,450 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	114,552,148 - 114,712,843 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	111,507,725 - 111,512,680 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	103,066,537 - 103,235,056 (-)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chronic recurrent multifocal osteomyelitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

Brodifacoum (EXP)

cadmium dichloride (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

Dichloroacetonitrile (ISO)

doxorubicin (ISO)

endosulfan (EXP)

indometacin (EXP)

inulin (ISO)

lead diacetate (ISO)

Mesaconitine (EXP)

nickel atom (ISO)

O-methyleugenol (ISO)

okadaic acid (ISO)

Oxadiazon (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

permethrin (ISO)

pirinixic acid (ISO)

rotenone (EXP)

sodium arsenite (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (EXP)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

mitochondrion (ISO)

Molecular Function

acylphosphatase activity (IBA,IEA)

hydrolase activity (IEA)

identical protein binding (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

pyruvate metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:1647162	PMID:8889548	PMID:12374855	PMID:16084386	PMID:18614015	PMID:34800366

Genomics

Comparative Map Data

Acyp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	108,402,837 - 108,572,367 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	108,402,544 - 108,633,318 (-)	Ensembl				GRCr8
mRatBN7.2	14	104,201,894 - 104,371,415 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	104,201,895 - 104,371,386 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	108,520,531 - 108,708,220 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	109,768,265 - 109,947,510 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	106,240,692 - 106,419,940 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	114,891,245 - 115,052,497 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	114,891,246 - 115,052,450 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	114,552,148 - 114,712,843 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	111,507,725 - 111,512,680 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	103,066,537 - 103,235,056 (-)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

ACYP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	53,971,113 - 54,305,300 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	53,970,838 - 54,305,300 (+)	Ensembl			hg38	GRCh38
GRCh37	2	54,198,250 - 54,532,437 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	54,195,914 - 54,385,941 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	54,254,060 - 54,443,931	NCBI
Celera	2	54,183,282 - 54,373,292 (+)	NCBI		Celera
Cytogenetic Map	2	p16.2	NCBI
HuRef	2	54,077,147 - 54,267,126 (+)	NCBI		HuRef
CHM1_1	2	54,274,220 - 54,464,574 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	53,967,329 - 54,301,490 (+)	NCBI		T2T-CHM13v2.0

Acyp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	30,455,991 - 30,599,778 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	30,455,991 - 30,599,587 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	30,505,992 - 30,649,608 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	30,505,991 - 30,649,587 (-)	Ensembl			mm10	GRCm38
MGSCv37	11	30,405,992 - 30,549,396 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	30,405,992 - 30,549,396 (-)	NCBI		MGSCv36	mm8
MGSCv36	11	30,471,086 - 30,615,251 (-)	NCBI		MGSCv36	mm8
Celera	11	32,993,107 - 33,048,388 (-)	NCBI		Celera
Cytogenetic Map	11	A4	NCBI
cM Map	11	18.16	NCBI

Acyp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955415	32,510,613 - 32,511,105 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACYP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	72,023,952 - 72,219,774 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	72,027,916 - 72,223,748 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	54,261,519 - 54,457,551 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	55,025,169 - 55,603,396 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	55,027,521 - 55,603,055 (+)	Ensembl			panPan2	panpan1.1

ACYP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	54,978,903 - 55,227,085 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	55,082,491 - 55,226,933 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	54,930,513 - 55,178,852 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	55,977,977 - 56,226,126 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	56,081,473 - 56,225,974 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	55,670,146 - 55,918,124 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	55,956,987 - 56,205,775 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	56,243,731 - 56,498,250 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Acyp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	27,800,651 - 27,955,767 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936491	615,666 - 771,199 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936491	615,515 - 770,636 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACYP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	86,945,647 - 87,109,139 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	86,945,635 - 87,231,376 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	91,728,767 - 91,892,606 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACYP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	52,642,008 - 52,846,243 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666045	58,875,794 - 59,097,600 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acyp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624833	7,602,724 - 7,684,508 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624833	7,603,041 - 7,685,340 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	71
Count of miRNA genes:	54
Interacting mature miRNAs:	67
Transcripts:	ENSRNOT00000067998
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	74255551	109089856	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	74255551	109089856	Rat

Markers in Region

D14Got164

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RGSC_v3.4	14	111,634,560 - 111,634,762	UniSTS	RGSC3.4
Celera	14	103,122,608 - 103,122,810	UniSTS
Cytogenetic Map	14	q22	UniSTS

RH127902

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	104,201,983 - 104,202,175 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	114,891,335 - 114,891,526	NCBI	Rnor6.0
Rnor_5.0	14	114,552,238 - 114,552,429	UniSTS	Rnor5.0
RGSC_v3.4	14	111,512,399 - 111,512,590	UniSTS	RGSC3.4
Celera	14	103,066,627 - 103,066,818	UniSTS
Cytogenetic Map	14	q22	UniSTS

RH125666

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	72,155,848 - 72,156,075 (+)	MAPPER	mRatBN7.2
mRatBN7.2	14	104,203,898 - 104,204,120 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	114,893,250 - 114,893,472	NCBI	Rnor6.0
Rnor_6.0	8	78,009,048 - 78,009,274	NCBI	Rnor6.0
Rnor_5.0	14	114,554,153 - 114,554,375	UniSTS	Rnor5.0
Rnor_5.0	8	75,066,832 - 75,067,058	UniSTS	Rnor5.0
RGSC_v3.4	8	75,971,020 - 75,971,246	UniSTS	RGSC3.4
RGSC_v3.4	14	111,510,453 - 111,510,675	UniSTS	RGSC3.4
Celera	14	103,068,541 - 103,068,763	UniSTS
Celera	8	69,579,470 - 69,579,696	UniSTS
Cytogenetic Map	14	q22	UniSTS
Cytogenetic Map	8	q24	UniSTS

fd02b11.x1

Rat Assembly	Chr	Position (strand)	Source
Celera	14	103,188,488 - 103,189,031	UniSTS
Celera	14	103,188,466 - 103,189,031	UniSTS
Cytogenetic Map	14	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	83	59	6	346	183	11	144	80	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001169145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273440	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273441	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010057399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AW521357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB613181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO404339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000067998 ⟹ ENSRNOP00000061028

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	108,402,838 - 108,572,322 (-)	Ensembl
mRatBN7.2 Ensembl	14	104,201,895 - 104,371,386 (-)	Ensembl
Rnor_6.0 Ensembl	14	114,891,246 - 115,052,450 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099667 ⟹ ENSRNOP00000092926

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	108,402,544 - 108,572,322 (-)	Ensembl
mRatBN7.2 Ensembl	14	104,202,498 - 104,371,386 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105033 ⟹ ENSRNOP00000078461

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	108,402,838 - 108,572,183 (-)	Ensembl
mRatBN7.2 Ensembl	14	104,201,895 - 104,371,247 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000129449 ⟹ ENSRNOP00000103202

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	108,402,838 - 108,633,318 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000149198 ⟹ ENSRNOP00000100853

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	108,445,501 - 108,572,322 (-)	Ensembl

RefSeq Acc Id:

NM_001169145 ⟹ NP_001162616

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	108,402,837 - 108,572,322 (-)	NCBI
mRatBN7.2	14	104,201,894 - 104,371,386 (-)	NCBI
Rnor_6.0	14	114,891,245 - 115,052,450 (-)	NCBI
Rnor_5.0	14	114,552,148 - 114,712,843 (-)	NCBI
RGSC_v3.4	14	111,507,725 - 111,512,680 (+)	RGD
Celera	14	103,066,537 - 103,235,056 (-)	RGD

Sequence:

show sequence

CGCAGAGAGGGAGCTCCCTGCTTGGGAGCTGGAGCGCCCGGTGTCCTGCCGTCCTCACTACGGA
CTGCGGACTGCGGTGTCCTGTGGTCTTGCGTGACCCGGCGCGTACCCGTCCTGCCAGGCGTCGG
TCCCAGAGCCCATGAGCCTCCTTCGCCTGGCGTCTGTCGCACTCTCCGCACCACACACCCCGCT
ACGGCTGCTCGCGAGAGGGCTGGCCGCCATGGCGGAGCCGCTTAAGTCTGTGGACTACGAAGTG
TTCGGGACAGTGCAAGGTGTTTGCTTCAGAATGTATACAGAAGGAGAAGCTAAGAAAAGAGGTC
TGGTTGGCTGGGTGAAGAATACAAGCAAAGGCACAGTGACAGGTCAAGTTCAAGGCCCTGAAGA
AAAGGTCAATTCCATGAAGTCCTGGCTGAGCAAGGTTGGGAGTCCTAGTTCTCGCATCGACCGG
GCCGACTTTTCTAACGAAAAAACAATCTCTAAACTGGAATACTCTAATTTTAGTATTCGATATT
AATAAAAGAAAGAGATCAATTGCAATGCTTATATTATAGAAGATAAAACATATTCTTAGGTTTA
TAATAGTAGGCGAGTAGGATTAAAAATGGAAAGTTTTTGTTCTGGAATTATACATTACTGAAAT
TTCTGAAACTGAAAAACTTTACTCACCTATGTTTTAGCAAGCAGAAACTAAATATTATAAAATA
AAATGTCATTATAAATTATCTAGTATGAACATTCAAGTTAAATATTGTCTTATGGAGTCATTCA
TTTCAGAAAATATTACAGTATTTGTTACTTTATATTACATTATATATGTTATTTGGCTAGACAT
AAAATAAAATTAACTATGTAAAATTACCTATGGATACTGTTGCCTAATTGACTTTTAAAGTCCT
CTGAATAATAACTTACTATTAAGGTTGAGCGATTAGCCTTAAAAATTGTTAAAATAAATTCGTG
TGATGATCACCATAACCAGAAAGTACTAGCAATAGACAGTTAGTGTGTAAACTTCTCCTTAAAC
TCAAGCCTGGTTCAGTACAAAGTTGGACTTACTTACTATCCTTGACTTAATTGTTCTGTAGTTT
GAAGAGTGTTGTTGTAAAAATATAAAAAATAAAAGAGTATTGGTGTCTTTTAAAAAAAAAAAAA
AAAA

hide sequence

RefSeq Acc Id:

XM_017599325 ⟹ XP_017454814

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	108,403,119 - 108,572,350 (-)	NCBI
mRatBN7.2	14	104,201,894 - 104,371,415 (-)	NCBI
Rnor_6.0	14	114,891,245 - 115,052,497 (-)	NCBI

Sequence:

show sequence

CCCTGGCACTAGCCTCGGTTTTCTTCAGAGAACAGAATCCTGGGGAGCGCAGAGAGGGAGCTCC
CTGCTTGGGAGCTGGAGCGCCCGGTGTCCGGCCGTCCTCACTACGGACTGCGGACTGCGGTGTC
CTGTGGTCTTGCGTGACCCGGCGCGTACCCGTCCTGCCAGGCGTCGGTCCCAGAGCCCATGAGC
CTCCTTCGCCTGGCGTCTGTCGCACTCTCCGCACCACACACCCCGCTACGGCTGCTCGCGAGAG
GGCTGGCCGCCATGGCGGAGCCGCTTAAGTCTGTGGACTACGAAGTGTTCGGGACAGTGCAAGG
TGTTTGCTTCAGAATGTATACAGAAGGAGAAGCTAAGAAAAGAGGTCTGGTTGGCTGGGTGAAG
AATACAAGCAAAGGCACAGTGACAGGTCAAGTTCAAGGCCCTGAAGAAAAGGTCAATTCCATGT
ACTTTTTCAGGAATACAGAGGCTGCATTTACTGCTCCATTGCTGCCTCCATTTCTTCCTGAGGA
AGTCCTGGCTGAGCAAGGTTGGGAGTCCTAGTTCTCGCATCGACCGGGCCGACTTTTCTAACGA
AAAAACAATCTCTAAACTGGAATACTCTAATTTTAGTATTCGATATTAATAAAAGAAAGAGATC
AATTGCAATGCTTATATTATAGAAGATAAAACATATTCTTAGGTTTATAATAGTAGGCGAGTAG
GATTAAAAATGGAAAGTTTTTGTTCTGGAATTATACATTACTGAAATTTCTGAAACTGAAAAAC
TTTACTCACCTATGTTTTAGCAAGCAGAAACTAAATATTATAAAATAAAATGTCATTATAAATT
ATCTAGTATGAACATTCAAGTTAAATATTGTCTTATGGAGTCATTCATTTCAGAAAATATTACA
GTATTTGTTACTTTATATTACATTATATATGTTATTTGGCTAGACATAAAATAAAATTAACTAT
GTAAAATTACCTATGGATACTGTTGCCTAATTGACTTTTAAAGTCCTCTGAATAATAACTTACT
ATTAAGGTTGAGCGATTAGCCTTAAAAATTGTTAAAATAAATTCGTGTGATGATCACCATAACC
AGAAAGTACTAGCAATAGACAGTTAGTGTGTAAACTTCTCCTTAAACTCAAGCCTGGTTCAGTA
CAAAGTTGGACTTACTTACTATCCTTGACTTAATTGTTCTGTAGTTTGAAGAGTGTTGTTGTAA
AAATATAAAAAATAAAAGAGTATTGGTGTCTTTTA

hide sequence

RefSeq Acc Id:

XM_039092253 ⟹ XP_038948181

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	108,403,119 - 108,572,050 (-)	NCBI
mRatBN7.2	14	104,201,894 - 104,371,179 (-)	NCBI

RefSeq Acc Id:

XM_063273440 ⟹ XP_063129510

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	108,516,063 - 108,572,367 (-)	NCBI

RefSeq Acc Id:

XM_063273441 ⟹ XP_063129511

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	108,434,293 - 108,572,359 (-)	NCBI

RefSeq Acc Id:

XM_063273442 ⟹ XP_063129512

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	108,490,644 - 108,572,137 (-)	NCBI

RefSeq Acc Id:

XR_010057399

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	108,434,293 - 108,572,359 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001162616	(Get FASTA)	NCBI Sequence Viewer
	XP_017454814	(Get FASTA)	NCBI Sequence Viewer
	XP_038948181	(Get FASTA)	NCBI Sequence Viewer
	XP_063129510	(Get FASTA)	NCBI Sequence Viewer
	XP_063129511	(Get FASTA)	NCBI Sequence Viewer
	XP_063129512	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL98045	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000061028
	ENSRNOP00000092926
GenBank Protein	P35745	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001162616 ⟸ NM_001169145
- UniProtKB:	D4A1G1 (UniProtKB/TrEMBL), A6JQC8 (UniProtKB/TrEMBL), A0A8I5ZKZ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSLLRLASVALSAPHTPLRLLARGLAAMAEPLKSVDYEVFGTVQGVCFRMYTEGEAKKRGLVGW VKNTSKGTVTGQVQGPEEKVNSMKSWLSKVGSPSSRIDRADFSNEKTISKLEYSNFSIRY hide sequence

RefSeq Acc Id:	XP_017454814 ⟸ XM_017599325
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6AGK8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSLLRLASVALSAPHTPLRLLARGLAAMAEPLKSVDYEVFGTVQGVCFRMYTEGEAKKRGLVGW VKNTSKGTVTGQVQGPEEKVNSMYFFRNTEAAFTAPLLPPFLPEEVLAEQGWES hide sequence

Ensembl Acc Id:

ENSRNOP00000061028 ⟸ ENSRNOT00000067998

RefSeq Acc Id:	XP_038948181 ⟸ XM_039092253
- Peptide Label:	isoform X5
- UniProtKB:	P35745 (UniProtKB/Swiss-Prot)

Ensembl Acc Id:

ENSRNOP00000092926 ⟸ ENSRNOT00000099667

Ensembl Acc Id:

ENSRNOP00000078461 ⟸ ENSRNOT00000105033

RefSeq Acc Id:	XP_063129511 ⟸ XM_063273441
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063129512 ⟸ XM_063273442
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063129510 ⟸ XM_063273440
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000100853 ⟸ ENSRNOT00000149198

Ensembl Acc Id:

ENSRNOP00000103202 ⟸ ENSRNOT00000129449

Protein Domains

Acylphosphatase-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P35745-F1-model_v2	AlphaFold	P35745	1-97	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1595836	AgrOrtholog
BioCyc Gene	G2FUF-14632	BioCyc
Ensembl Genes	ENSRNOG00000042419	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000067998	ENTREZGENE
	ENSRNOT00000099667	ENTREZGENE
Gene3D-CATH	3.30.70.100	UniProtKB/Swiss-Prot
InterPro	Acylphosphatase	UniProtKB/Swiss-Prot
	Acylphosphatase-like_dom	UniProtKB/Swiss-Prot
	Acylphosphatase-like_dom_sf	UniProtKB/Swiss-Prot
	Acylphosphatase_CS	UniProtKB/Swiss-Prot
NCBI Gene	364224	ENTREZGENE
PANTHER	ACYLPHOSPHATASE-2	UniProtKB/Swiss-Prot
	PTHR10029	UniProtKB/Swiss-Prot
Pfam	Acylphosphatase	UniProtKB/Swiss-Prot
PhenoGen	Acyp2	PhenoGen
PRINTS	ACYLPHPHTASE	UniProtKB/Swiss-Prot
PROSITE	ACYLPHOSPHATASE_1	UniProtKB/Swiss-Prot
	ACYLPHOSPHATASE_2	UniProtKB/Swiss-Prot
	ACYLPHOSPHATASE_3	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000042419	RatGTEx
Superfamily-SCOP	SSF54975	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZKZ2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AGK8	ENTREZGENE, UniProtKB/TrEMBL
	A6JQC8	ENTREZGENE, UniProtKB/TrEMBL
	ACYP2_RAT	UniProtKB/Swiss-Prot
	D4A1G1	ENTREZGENE, UniProtKB/TrEMBL
	P35745	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-01	Acyp2	acylphosphatase 2	Acyp2	acylphosphatase 2, muscle type	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-07-29	Acyp2	acylphosphatase 2, muscle type	LOC100361559	acylphosphatase-2-like	Data merged from RGD:2319909	737654	PROVISIONAL
2010-05-05	LOC100361559	acylphosphatase-2-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2009-12-16	LOC364224	similar to Acylphosphatase, muscle type isozyme (Acylphosphate phosphohydrolase)	LOC682245	similar to Acylphosphatase, muscle type isozyme (Acylphosphate phosphohydrolase)	Data merged from RGD:1585746	737654	APPROVED
2009-12-16	Acyp2	acylphosphatase 2, muscle type	LOC364224	similar to Acylphosphatase, muscle type isozyme (Acylphosphate phosphohydrolase)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC364224	similar to Acylphosphatase, muscle type isozyme (Acylphosphate phosphohydrolase)			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC682245	similar to Acylphosphatase, muscle type isozyme (Acylphosphate phosphohydrolase)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)