Advanced Search (OLGA)

Gene: Pcdhb20 (protocadherin beta 20) Rattus norvegicus

Analyze

Symbol:

Pcdhb20

Name:

protocadherin beta 20

RGD ID:

1594228

Description:

Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be active in plasma membrane. Orthologous to human PCDHB14 (protocadherin beta 14); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC680203; Pcdhb14; protocadherin beta 14; protocadherin beta-14; similar to Protocadherin beta 14 precursor (PCDH-beta14)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	29,485,888 - 29,489,282 (+)	NCBI		GRCr8
GRCr8 Ensembl	18	29,454,999 - 29,489,427 (+)	Ensembl		GRCr8 Ensembl
mRatBN7.2	18	29,211,878 - 29,215,272 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	29,211,883 - 29,215,258 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	29,339,009 - 29,342,384 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	30,101,010 - 30,104,385 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	29,436,320 - 29,439,695 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	30,581,530 - 30,584,905 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	30,581,530 - 30,584,905 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	30,288,725 - 30,292,100 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	30,316,122 - 30,319,497 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	18	28,907,680 - 28,911,055 (+)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant intellectual developmental disorder 31 (ISO)

familial adenomatous polyposis 1 (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

5-azacytidine (ISO)

acetamide (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

cyclosporin A (ISO)

DDE (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethanol (ISO)

folic acid (ISO)

formaldehyde (ISO)

lead diacetate (EXP,ISO)

mancozeb (ISO)

maneb (ISO)

methylmercury chloride (ISO)

nitrofen (EXP)

panobinostat (ISO)

paracetamol (EXP)

paraquat (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triptonide (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc sulfate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IBA,IEA)

homophilic cell adhesion via plasma membrane adhesion molecules (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA)

Molecular Function

calcium ion binding (IEA)

cell adhesion molecule binding (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:14672974	PMID:15744052

Genomics

Comparative Map Data

Pcdhb20
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	29,485,888 - 29,489,282 (+)	NCBI		GRCr8
GRCr8 Ensembl	18	29,454,999 - 29,489,427 (+)	Ensembl		GRCr8 Ensembl
mRatBN7.2	18	29,211,878 - 29,215,272 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	29,211,883 - 29,215,258 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	29,339,009 - 29,342,384 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	30,101,010 - 30,104,385 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	29,436,320 - 29,439,695 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	30,581,530 - 30,584,905 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	30,581,530 - 30,584,905 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	30,288,725 - 30,292,100 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	30,316,122 - 30,319,497 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	18	28,907,680 - 28,911,055 (+)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

PCDHB14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	141,223,343 - 141,227,759 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	141,223,343 - 141,227,759 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	140,602,915 - 140,607,331 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	140,583,262 - 140,586,044 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	140,583,261 - 140,586,042	NCBI
Celera	5	136,679,902 - 136,682,684 (+)	NCBI		Celera
Cytogenetic Map	5	q31.3	NCBI
HuRef	5	135,748,139 - 135,750,921 (+)	NCBI		HuRef
CHM1_1	5	140,036,278 - 140,039,060 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	141,748,654 - 141,753,070 (+)	NCBI		T2T-CHM13v2.0

Pcdhb20
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	37,637,332 - 37,640,713 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	37,637,317 - 37,640,875 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	37,504,264 - 37,507,660 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	37,504,264 - 37,507,822 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	37,663,918 - 37,667,314 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	37,630,263 - 37,633,634 (+)	NCBI		MGSCv36	mm8
Celera	18	38,855,575 - 38,858,970 (+)	NCBI		Celera
Cytogenetic Map	18	B3	NCBI
cM Map	18	19.51	NCBI

LOC100981837
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	136,468,306 - 136,477,462 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	134,612,321 - 134,617,014 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	136,584,741 - 136,589,504 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	142,698,484 - 142,703,146 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	142,700,427 - 142,712,829 (+)	Ensembl	panpan1.1		panPan2

LOC487175
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	36,226,490 - 36,232,201 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	36,229,411 - 36,231,807 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	33,280,369 - 33,284,104 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	36,683,068 - 36,686,803 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	36,684,013 - 36,686,409 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	33,757,124 - 33,760,859 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	34,568,123 - 34,571,856 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	35,375,775 - 35,379,510 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101964548
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	151,327,698 - 151,331,167 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936504	12,901,965 - 12,904,619 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC103244680
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	43,845,822 - 43,858,944 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	43,846,217 - 43,858,312 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	33,991,869 - 34,003,981 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Pcdhb20
13 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	74
Count of miRNA genes:	62
Interacting mature miRNAs:	69
Transcripts:	ENSRNOT00000048166
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25071126	83910656	Rat
2301409	Cm70	Cardiac mass QTL 70		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	18	7065728	52065728	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	22015562	61600538	Rat
1331735	Rf44	Renal function QTL 44	2.981		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	18	15642280	31610627	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	12216684	31644508	Rat
2301413	Bp318	Blood pressure QTL 318		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	26822186	71822186	Rat
12904716	Am21	Aortic mass QTL 21		0.005	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	7065728	52065728	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	23494057	85487725	Rat
12904714	Cm131	Cardiac mass QTL 131		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	7065728	52065728	Rat
12904715	Cm132	Cardiac mass QTL 132		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	7065728	52065728	Rat
6903345	Bp349	Blood pressure QTL 349	3.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
12904668	Bw188	Body weight QTL 188		0.03	body mass (VT:0001259)	body weight (CMO:0000012)	18	26822186	71822186	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	15226101	42690662	Rat
12904669	Cm125	Cardiac mass QTL 125		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	26822186	71822186	Rat
6903347	Bp350	Blood pressure QTL 350	4.4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
12904670	Cm126	Cardiac mass QTL 126		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	26822186	71822186	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5460455	42690191	Rat
6903349	Bp351	Blood pressure QTL 351	3.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
631509	Sald2	Serum aldosterone level QTL 2	2.9		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	18	26415821	71415821	Rat
6903351	Bp352	Blood pressure QTL 352	3.3		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
12904677	Kidm72	Kidney mass QTL 72		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	26822186	71822186	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
12904673	Cm127	Cardiac mass QTL 127		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	26822186	71822186	Rat
12904675	Am19	Aortic mass QTL 19		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	26822186	71822186	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	12216684	31644508	Rat
1331775	Bp235	Blood pressure QTL 235	3.201		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	31610627	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	44930869	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19553532	85493247	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	12066482	57066482	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	12066482	85493247	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	3811902	30809809	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34566578	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4482648	49482648	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	54490981	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	12066482	85493247	Rat
11565454	Kidm59	Kidney mass QTL 59		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	7065728	52065728	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	86134022	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34566578	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	4307354	49307354	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	11	49	111	88	87	56	25	56	6	215	97	11	91	45	59	31	14	14

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC131360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000048166 ⟹ ENSRNOP00000042052

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	29,454,999 - 29,489,427 (+)	Ensembl
mRatBN7.2 Ensembl	18	29,211,883 - 29,215,258 (+)	Ensembl
Rnor_6.0 Ensembl	18	30,581,530 - 30,584,905 (+)	Ensembl

RefSeq Acc Id:

NM_001109395 ⟹ NP_001102865

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	29,485,888 - 29,489,282 (+)	NCBI
mRatBN7.2	18	29,211,878 - 29,215,272 (+)	NCBI
Rnor_6.0	18	30,581,530 - 30,584,905 (+)	NCBI
Rnor_5.0	18	30,288,725 - 30,292,100 (+)	NCBI
RGSC_v3.4	18	30,316,122 - 30,319,497 (+)	RGD
Celera	18	28,907,680 - 28,911,055 (+)	RGD

Sequence:

show sequence

GTGAGAAGGGACGTATTACAGGAGCTTCACCGACGGAGCTGACAAGGGATTTTCAATAGAAATA
TCGGACCTTTGTCTCCCAAATTTGGGATTGAATTTAAATTTTGGAGTAGAAGAAGTCACCTGAA
GGAACCATGGGAAACAGAAAGACTATCATCCTGCAGAAACGGCAAGTCTTGGTTTTCTTTGTTT
TGCTGGGATTGTCTCGGGCGAGTGCTGAGTCTTTGCGCTATTCTGTAGCAGAGGAAACAGAAAT
TGGCTCTTTTGTGGCTAATCTGGCAAGGGATTTAGGGCTGGGGGTTGCGGAGCTGTCCTCCAGG
GAGGCCAGGATAGTGTCAGACGATAATAAAAAGCATTTACTCCTTAATTTGCTGACCGGAGATG
TGCTCCTGAGTGAGCGACTGGACCGTGAAGAGCTGTGTGGCTCCACCGAGCCCTGTGTGCTGCC
CTTTCAGGTGGTACTGGAAGACCCTTTACAGTTCTATCGAGCTGAGCTGCATGTCAGAGACATA
AATGATCACGCCCCTACATTCCTAGACAAGGAAATAACTATTAAAATACCAGAAAGCGCTGCTA
TCGGAGCCACATTTTTAATTGAGAATGCACAAGATCTGGACATAGGAAGCAACAGTCTCCAGGA
CTACAGCATTAGCCCCAGTTCTCATTTCTATGTTAAAATTCATGAGAGTGGTGATGGAAAGATA
TATCCAGAGCTGGTACTGGACAAAGCTTTAGATCATGAGGAAGAATCTGAGCTTAGATTGACAC
TTACAGCATTGGATGGCGGGTCTCCACCCAGGTCTGGGACAACATTAGTTCTCATAAAAGTCTT
GGACATCAACGATAATGCTCCTGAGTTTGCTCAGAATTTCTATGAGGTGCAGGTCCCAGAGGAC
ACACCCATTGGCTCCAGTATTATTACTATCTCTGCTAAAGATTTAGATATGGGAAATTATGGGA
AAATATCATATTCATTTTTGCATGCAACAGAAGATGTTAGAAAAACCTTTGAAATCAACCCAAC
ATCTGGGGAAGTCAATTTGAGATCACTGCTGGATTTTGAAGTAATACAGTCCTATTCTGTAACT
ATCCAAGCAACAGATGGTGGAGGTCTTTCAGCAAAATGCACTCTTTCAGTTAAAGTATTAGATA
TAAATGACAATGCACCAGAAGTGATCATATCATCGGTTACAAAGACAATTCCAGAGAATGCTTC
AGAGACCCTGATCACTCTGTTCAGTGTCCGAGATCAAGACTCTGGAGACAATGGAAGGATCCTT
TGCTCTATTCCGGATGACCTTCCATTTATTCTAAAGCCCACCTTCAAGAATTTTTTCACTCTAC
TTTCTGAAAAAGCACTGGACAGAGAAAGTAGAGCTGAGTACAACATCACCATCACTGTCTCAGA
TCTGGGCACACCCAGGCTCACAACCCAGCACACCATAACAGTGCAGGTGTCTGACATCAACGAC
AACGCCCCCGCCTTCACCCAAACCTCCTACACCATGTTTGTCCACGAGAACAACAGCCCCGCCC
TGCACATAGGCACCATCAGTGCCACAGACTCAGACTCAGGCTCCAATGCCCACATCACCTACTC
GCTGATGCCGCCTCGAGACCCACAGCTGGCCCTCGACTCCCTCATCTCCATCAATGCTGACAAC
GGGCAGCTGTTCGCACTCAGGGCGCTGGACTATGAGGTGCTGCAGGCCTTCGAGTTCCGCGTGG
GTGCCACAGACAGAGGCTCACCCGCGCTCAGCAGCCAGGCTCTGGTGCGCGTGGTGGTGCTGGA
CGACAATGACAATGCGCCCTTCGTGCTCTACCCGCTGCAGAATGCCTCAGCGCCCTACACAGAG
CTGCTGCCCAGGGCGGCAGAGCCTGGATACCTGGTTACCAAGGTGGTAGCTGTGGACCGCGACT
CTGGCCAGAATGCCTGGCTGTCATTCCAGCTGCTCAAAGCCACGGAGCCGGGGCTGTTCAGCGT
GTGGGCGCACAATGGCGAGGTACGCACCTCCAGGCTGCTGAGCGAGCGCGATGCACCCAAGCAC
AAACTGCTGCTGATGGTCAAGGACAATGGAGATCCTCCGCGCTCTGCCAGTGTTATGTTGCACG
TGCTAGTGGTAGATGGCTTCTCTCAGCCCTACCTGCCTCTGCCAGAGGTGGCGCACAATCCTGC
ACACGACGAGGACACTCTAACACTGTACCTGGTCATAGCCTTGGCATCTGTGTCTTCTCTCTTC
CTCTTGTCTGTGCTGCTGTTCGTGGGGGTGAGGCTGTGCAAGAAGGCCAGGGCAGCTTCTCTGG
GTGGCTGCTCTGTGCCCGAGGGCCACTTTCCTGGCCACCTGGTGGACGTTACCGGCACTGGAAC
CCTGTCCCAGAACTACCAGTATGAGGTGTGTTTGACAGGAAGTACTGGGACAAACGAGTTCAAA
TTCCTGAAGCCAGTCATGCCCAGTCTTCAACTCCAGGACCCCGATTCTAATATGCTGGTAAAGG
AGAACTTTCGGAATAGCCTGGGTTTTAATATTCAATAAAAATTTCCTTTAAACTTTTATTATTT
TCTTTCTATTGACAAATTGCAAAGGCTTGTTTTTTTTTTTCTTAATCTGTATTGGATTTAAGGT
CTTCCTGATGTTGCATTCATTTTCATATCACGTGTTTTTCTCAGAGTTACTTTGAAAATCTTTA
CTGGGATAAGAGTGATGCAAAGAAACACGTTTTGTTTTATTTTGTTGAAGTGTTGTGTTAACCG
GTCTGCTGTTTCTTATATAAGACCCAGCAATGGAAATGCTGGTTTAAGTATTTAGAATGGATGT
GTTGAGCTAGTGATTGCTATAATACTTCGGGGAGTCCACAGCAAGCAGCCCTGAATGGGATCTA
CAGCAAAAGACATGAAGGGAGGGAGGGAAGGAACTAAAAAGGGGCAAATGTTACTATATATGGA
ATTTCCCAATATGCTATTAAAACCCAACAAACAGAGAGTCTAAGGGTTGTTTTACCTGGTTAGA
AACTGTATTGGGATCATTTGCAGTATTCTCTGTCAGATTATTTCAGCAGAAAAAATAATGTTCT
TTAAATGCTGCCCTTCCAAATCCAGTAGTAGAGGTCTTTGTTTCACAGTGTTTTCAAGAATTGC
TTTCTTAGATCTCTGATTTCTAATGAAGCTTTCTAATTATCAAAATACTCTATGTTTTGATGTT
GTTGTTTTGTTGTCTTTAAATACACATTTTCTTGGTTAAAATTTGTGGTACTCTATACCACTCA
TTACTAAAGCAGATAATAGTTCATAATCATAATCTTATTTATCTTATAAATAATCTTATATCAG
AAAAGAACAGGATAAAATCTTCCTAGGAAATAAAATAAAGATTTTAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102865	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL76358	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000042052.3

RefSeq Acc Id:	NP_001102865 ⟸ NM_001109395
- Peptide Label:	precursor
- UniProtKB:	D4A7P5 (UniProtKB/TrEMBL), A6J376 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNRKTIILQKRQVLVFFVLLGLSRASAESLRYSVAEETEIGSFVANLARDLGLGVAELSSREA RIVSDDNKKHLLLNLLTGDVLLSERLDREELCGSTEPCVLPFQVVLEDPLQFYRAELHVRDIND HAPTFLDKEITIKIPESAAIGATFLIENAQDLDIGSNSLQDYSISPSSHFYVKIHESGDGKIYP ELVLDKALDHEEESELRLTLTALDGGSPPRSGTTLVLIKVLDINDNAPEFAQNFYEVQVPEDTP IGSSIITISAKDLDMGNYGKISYSFLHATEDVRKTFEINPTSGEVNLRSLLDFEVIQSYSVTIQ ATDGGGLSAKCTLSVKVLDINDNAPEVIISSVTKTIPENASETLITLFSVRDQDSGDNGRILCS IPDDLPFILKPTFKNFFTLLSEKALDRESRAEYNITITVSDLGTPRLTTQHTITVQVSDINDNA PAFTQTSYTMFVHENNSPALHIGTISATDSDSGSNAHITYSLMPPRDPQLALDSLISINADNGQ LFALRALDYEVLQAFEFRVGATDRGSPALSSQALVRVVVLDDNDNAPFVLYPLQNASAPYTELL PRAAEPGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTSRLLSERDAPKHKL LLMVKDNGDPPRSASVMLHVLVVDGFSQPYLPLPEVAHNPAHDEDTLTLYLVIALASVSSLFLL SVLLFVGVRLCKKARAASLGGCSVPEGHFPGHLVDVTGTGTLSQNYQYEVCLTGSTGTNEFKFL KPVMPSLQLQDPDSNMLVKENFRNSLGFNIQ hide sequence

Ensembl Acc Id:

ENSRNOP00000042052 ⟸ ENSRNOT00000048166

Protein Domains

Cadherin

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A7P5-F1-model_v2	AlphaFold	D4A7P5	1-799	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1594228	AgrOrtholog
BioCyc Gene	G2FUF-7820	BioCyc
Ensembl Genes	ENSRNOG00000033123	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000048166.4	UniProtKB/TrEMBL
Gene3D-CATH	Cadherins	UniProtKB/TrEMBL
InterPro	Cadherin	UniProtKB/TrEMBL
	Cadherin-like	UniProtKB/TrEMBL
	Cadherin_C	UniProtKB/TrEMBL
	Cadherin_CS	UniProtKB/TrEMBL
	Cadherin_N	UniProtKB/TrEMBL
	Protocadherin/Cadherin-CA	UniProtKB/TrEMBL
KEGG Report	rno:680203	UniProtKB/TrEMBL
NCBI Gene	680203	ENTREZGENE
PANTHER	CADHERIN-87A	UniProtKB/TrEMBL
	PROTOCADHERIN BETA-14	UniProtKB/TrEMBL
Pfam	Cadherin	UniProtKB/TrEMBL
	Cadherin_2	UniProtKB/TrEMBL
	Cadherin_C_2	UniProtKB/TrEMBL
PhenoGen	Pcdhb20	PhenoGen
PRINTS	CADHERIN	UniProtKB/TrEMBL
PROSITE	CADHERIN_1	UniProtKB/TrEMBL
	CADHERIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000033123	RatGTEx
SMART	SM00112	UniProtKB/TrEMBL
Superfamily-SCOP	Cadherin	UniProtKB/TrEMBL
UniProt	A6J376	ENTREZGENE, UniProtKB/TrEMBL
	D4A7P5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-07-08	Pcdhb20	protocadherin beta 20	LOC683325	similar to Protocadherin beta 14 precursor (PCDH-beta14)	Data merged from RGD:1588044	1643240	APPROVED
2008-03-17	Pcdhb20	protocadherin beta 20	Pcdhb14	protocadherin beta 14	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Pcdhb14	protocadherin beta 14	LOC680203	similar to Protocadherin beta 14 precursor (PCDH-beta14)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC680203	similar to Protocadherin beta 14 precursor (PCDH-beta14)			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC683325	similar to Protocadherin beta 14 precursor (PCDH-beta14)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar