Slc39a7 (solute carrier family 39 member 7)

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Gene: Slc39a7 (solute carrier family 39 member 7) Rattus norvegicus

Analyze

Symbol:

Slc39a7

Name:

solute carrier family 39 member 7

RGD ID:

1593280

Description:

Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in B cell differentiation; intracellular zinc ion homeostasis; and zinc ion transmembrane transport. Predicted to be located in endoplasmic reticulum and nucleoplasm. Human ortholog(s) of this gene implicated in agammaglobulinemia 9. Orthologous to human SLC39A7 (solute carrier family 39 member 7); INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Histidine-rich membrane protein; Ke4; MGC94153; RT1 class I, locus Ke4; RT1 class I, locus Ke4 (mapped); RT1 region expressed gene KE4; RT1-Ke4; RT1-Ke4_mapped; Rt1Ke4; solute carrier family 39 (zinc transporter), member 7; zinc transporter SLC39A7

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC39A7 (solute carrier family 39 member 7)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Slc39a7 (solute carrier family 39 (zinc transporter), member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc39a7 (solute carrier family 39 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC39A7 (solute carrier family 39 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC39A7 (solute carrier family 39 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc39a7 (solute carrier family 39 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC39A7 (solute carrier family 39 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC39A7 (solute carrier family 39 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc39a7 (solute carrier family 39 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Slc39a7 (solute carrier family 39 (zinc transporter), member 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SLC39A7 (solute carrier family 39 member 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc39a7 (solute carrier family 39 member 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Catsup	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YKE4	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	zipt-7.1	Alliance	DIOPT (OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	zipt-7.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	4,823,166 - 4,826,538 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	4,822,012 - 4,826,537 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	5,574,751 - 5,578,325 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	20	4,936,505 - 4,940,079 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	20	5,417,587 - 5,420,957 (+)	NCBI	Rnor_WKY
Rnor_6.0	20	3,819,416 - 3,822,788 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	3,819,414 - 3,822,778 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	5,898,747 - 5,902,119 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	4,961,280 - 4,964,652 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	20	6,423,351 - 6,426,723 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

agammaglobulinemia 9 (ISO)

autosomal dominant intellectual developmental disorder 5 (ISO)

genetic disease (ISO)

JMP syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

4,5,6,7-TETRABROMOBENZOTRIAZOLE (ISO)

acrylamide (EXP)

Aroclor 1254 (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

clofibric acid (EXP)

clozapine (ISO)

coumarin (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

elemental selenium (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

folic acid (ISO)

furan (EXP)

glafenine (EXP)

haloperidol (ISO)

ionomycin (ISO)

methidathion (ISO)

N-nitrosodiethylamine (EXP)

ochratoxin A (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

pyrithione (ISO)

selenium atom (ISO)

tamoxifen (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

tolcapone (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

B cell differentiation (ISO,ISS)

intracellular zinc ion homeostasis (IBA,ISO,ISS)

regulation of ferroptosis (ISO,ISS)

skin epidermis development (ISO,ISS)

zinc ion transmembrane transport (IBA,ISO)

Cellular Component

endoplasmic reticulum (ISO)

endoplasmic reticulum membrane (ISO)

Golgi apparatus (IEA)

nucleoplasm (IEA,ISO)

Molecular Function

protein binding (ISO)

zinc ion transmembrane transporter activity (IBA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:1300435	PMID:10970097	PMID:12477932	PMID:28232492	PMID:29307859

Genomics

Comparative Map Data

Slc39a7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	4,823,166 - 4,826,538 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	4,822,012 - 4,826,537 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	5,574,751 - 5,578,325 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	20	4,936,505 - 4,940,079 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	20	5,417,587 - 5,420,957 (+)	NCBI	Rnor_WKY
Rnor_6.0	20	3,819,416 - 3,822,788 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	3,819,414 - 3,822,778 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	5,898,747 - 5,902,119 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	4,961,280 - 4,964,652 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	20	6,423,351 - 6,426,723 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

SLC39A7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	33,200,867 - 33,204,437 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	6	33,200,305 - 33,204,439 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	33,168,644 - 33,172,214 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	33,276,581 - 33,280,192 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	33,276,674 - 33,280,191	NCBI
Celera	6	34,722,969 - 34,726,580 (+)	NCBI		Celera
Cytogenetic Map	6	p21.32	NCBI
HuRef	6	32,910,648 - 32,914,259 (+)	NCBI		HuRef
CHM1_1	6	33,170,477 - 33,174,088 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	33,022,220 - 33,025,790 (+)	NCBI		T2T-CHM13v2.0

Slc39a7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	34,247,240 - 34,250,664 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	34,247,243 - 34,250,656 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	34,028,266 - 34,031,690 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	34,028,269 - 34,031,682 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	34,165,211 - 34,168,635 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	33,638,727 - 33,642,012 (-)	NCBI		MGSCv36	mm8
Celera	17	36,774,396 - 36,777,820 (-)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	17.98	NCBI

Slc39a7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	1,774,301 - 1,778,092 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	1,774,301 - 1,778,092 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC39A7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	6	33,887,955 - 33,891,558 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	33,887,955 - 33,891,558 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	6	32,773,016 - 32,776,650 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

SLC39A7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	2,663,807 - 2,667,527 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	2,663,515 - 2,669,917 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	2,745,071 - 2,748,667 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	2,994,241 - 2,998,264 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	2,994,250 - 2,998,245 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	2,662,854 - 2,666,450 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	2,744,221 - 2,747,817 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	2,818,793 - 2,822,389 (+)	NCBI		UU_Cfam_GSD_1.0

Slc39a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	38,305,147 - 38,309,308 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	25,650,959 - 25,655,077 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936476	25,650,957 - 25,655,072 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC39A7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	25,242,971 - 25,247,404 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	25,242,862 - 25,247,407 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	29,756,216 - 29,760,619 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC39A7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	38,870,726 - 38,874,334 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	38,870,609 - 38,873,909 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	33,035,077 - 33,038,710 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc39a7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	23,603,141 - 23,640,406 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	23,602,940 - 23,606,903 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc39a7
26 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	103
Count of miRNA genes:	81
Interacting mature miRNAs:	94
Transcripts:	ENSRNOT00000000541
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24159021	Rat
1600382	Edcs3	Endometrial carcinoma susceptibility QTL3	3.5	0.003	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	20	1	25159026	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
2306850	Pia40	Pristane induced arthritis QTL 40		0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1527959	5304575	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	2892597	26381954	Rat
1300152	Bp195	Blood pressure QTL 195	3.46		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	3621649	9243559	Rat
1331772	Cdexp2	CD45RC expression in CD8 T cells QTL 2	5.7		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	20	3621649	10078919	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	3621656	14101050	Rat
61474	Eae1	Experimental allergic encephalomyelitis QTL 1	3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	20	4606607	6691706	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	4606607	17617956	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	4606607	17617956	Rat
7175096	Tcs1	T cell selection QTL 1			T cell selection	expression	20	4727078	5024580	Rat

Markers in Region

RH129332

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	4,826,327 - 4,826,514 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	3,819,440 - 3,819,626	NCBI	Rnor6.0
Rnor_5.0	20	5,898,771 - 5,898,957	UniSTS	Rnor5.0
RGSC_v3.4	20	4,964,442 - 4,964,628	UniSTS	RGSC3.4
Celera	20	6,426,513 - 6,426,699	UniSTS
RH 3.4 Map	9	391.29	UniSTS
Cytogenetic Map	20	p12	UniSTS

BM385817

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	4,824,348 - 4,824,536 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	3,821,418 - 3,821,605	NCBI	Rnor6.0
Rnor_5.0	20	5,900,749 - 5,900,936	UniSTS	Rnor5.0
RGSC_v3.4	20	4,962,463 - 4,962,650	UniSTS	RGSC3.4
Celera	20	6,424,534 - 6,424,721	UniSTS
RH 3.4 Map	20	68.9	UniSTS
Cytogenetic Map	20	p12	UniSTS

Slc39a7

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	4,825,108 - 4,826,342 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	3,819,612 - 3,820,845	NCBI	Rnor6.0
Rnor_5.0	20	5,898,943 - 5,900,176	UniSTS	Rnor5.0
RGSC_v3.4	20	4,963,223 - 4,964,456	UniSTS	RGSC3.4
Celera	20	6,425,294 - 6,426,527	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	6	9	74	35	40	11	6
Low							2	2			1		2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001008885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001164744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098503	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC098547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX883042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DY547565	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000000541 ⟹ ENSRNOP00000000541

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	4,822,012 - 4,826,537 (+)	Ensembl
Rnor_6.0 Ensembl	20	3,819,423 - 3,822,754 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000077357 ⟹ ENSRNOP00000071707

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	3,819,414 - 3,822,778 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000083873

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	3,821,535 - 3,822,130 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089622

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	3,819,879 - 3,820,397 (-)	Ensembl

RefSeq Acc Id:

NM_001008885 ⟹ NP_001008885

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	4,823,204 - 4,826,538 (+)	NCBI
Rnor_6.0	20	3,819,416 - 3,822,750 (-)	NCBI
Rnor_5.0	20	5,898,747 - 5,902,119 (-)	NCBI
RGSC_v3.4	20	4,961,280 - 4,964,652 (+)	RGD
Celera	20	6,423,389 - 6,426,723 (+)	NCBI

Sequence:

show sequence

CGAGAACGGAGAGGATCCCGGAGCCGGTGAGAACTCCCTGCTGCTCCCTTACGGCGCTTTCCAT
GCTTTTACCCTAACTACTGAGCCATAGAGACGAGGGCCCAGAGAGACCGTAAAGTTGCGGATCA
AAGGCTAGAGCGGTGTTGGGGGGTGGGAGGTTTGGGGGAGCTGCATCCAGGAAGGGTGTCGGGG
ATGAAGAGAACTGGCCTTGGGAACAATGTAAGAGGGGAGCAAGTGGTATAGAGTGGACGGAAGG
GCTTCAAGGGAAGCGGATCCCGCATAGGTAGAGAGTCAAGTAGACTCGTCTCTGTTCCTCTGGT
CAGCGTGATGGCCAGGGTCCTGCGGGACCCCCACTGGGTGGCTGTGGGACTGCTGACCTGGGCA
GCTTTGGGGCTGCTGGTAGCCGGACACGAGGGTCATGGTGACCTGCACAGAGACGTGGAAGAGG
ACTTCCATGGCCACAGCCACGGACACTCACATGAAGATTTCCACCATGGCCACAGCCATGGCCA
TGGCCACACTCATGAGAGCATCTGGCATGGGCATGCCCACAGCCACGACCATGGACATTCACGG
GAGGATGTGCACCATGGCCATAGCCATGGCCACTCCCACGATAGCCTCCACCACAGAGGACATG
GACATAGCCATGGAGCCTCTAGGGAGGCTGGGGCTCCAGGCATCAAGCACCACCTGGACACTGT
CACCCTCTGGGCCTATGCACTGGGGGCCACAGTGCTAATCTCCGCGGCTCCCTTCTTCGTGCTC
TTCCTCATCCCTGTGGAGTCAAACTCTCCCAGGCATCGTTCTCTGCTCCAGATCCTGCTCAGTT
TTGCTTCTGGGGGGCTCCTGGGAGATGCCTTCCTCCACCTCATCCCTCACGCCTTGGAACCTCA
TTCGCACGATACTCCGGCACAGCCTGGCCACGGACACTCCCACAGCGGCCAGGGCCCCATTCTC
TCTGTGGGGCTGTGGGTTCTCAGTGGGATTGTCGCCTTTCTTGTGGTGGAGAAGTTTGTGAGAC
ACGTGAAAGGAGGGCACGGACACGCGCACGCGCACGGACACGGACACTCGCACGGAGACAGCCA
CGCGCACGGACACAGCCACGCACACGGGGATAGGCATGAGTGTCCTTCAAAGGGAAAGCCCAGT
TCAGAGGATGAAAAGGAAGCAGGGGGCTTGCGGAAAAGGAGAGGAGGAGACACGGGGCCCAGAG
ATGGCCCTCTGAAACCTCAGAACCCTGAAGAAGAAAAAACAGGCTCAGACCTGCGTGTGTCTGG
GTACCTGAATCTGGCTGCTGACTTGGCACACAACTTCACAGACGGGCTGGCCATTGGTGCTTCC
TTCCGTGGGGGCCGAGGGCTTGGGATCCTGACCACGATGACAGTCCTGCTGCATGAAGTGCCTC
ATGAGGTTGGGGACTTTGCCATCTTGGTCCAGTCTGGCTGCAGCAAGAAACAGGCGATGCGTCT
GCAACTCTTGACTGCAATTGGAGCATTGGCAGGCACAGCCTGTGCCCTTCTCACTGAGGGAGGG
GCAGTGGGCAGTGAGGTGGCTGGTGGTGCAGGTCCCGGCTGGGTTCTGCCATTCACTGCAGGTG
GATTCATCTATGTGGCAACAGTGTCCGTGCTACCTGAGCTACTGAGAGAGGCATCCCCGTTACA
GTCTCTCTTGGAGGTGCTGGGGCTGCTGGGGGGCGTTGCCATGATGGTACTGATTGCCCATCTT
GAGTGAGGGGTGGGTGACCTGTCCTACCCCTAACTCCAAAATAAAGGCAGTTGGGACCCTGGCC
AGTGCATTGTCAGGAGGCTCAGCCTGGAGAATGGCATCTTTGGTATTTGAGGCCTTAGAGGTAT
GAGAGTCACACAGAGCATGAGAGGCCAGAGGGACCATGCTGTGGGAGACAGCCCAGCAGTGTTG
TTGGTTTTGGAGAAATAAATGGGACCATGAAGAAGGCTGGGAGACAGTAGCCTACCTGGTGGTC
CCTAGTCTACGTTTTCCCAGCACCAGCATGCCACACAAGGGTCCTCCAAGGTCCATCTCCCTCT
GAACTGGTTAGTGATGGCTTCAGGGAAGGCCTGGCAGAAGGACTGGGGTAGACATCAATCGTGT
GTCCTGATTTGAGGGGGTGGGTGGTGTTCCTTGGAAAAATGTCATGGCCTGATTTTTGTTTCTA
CTCATTTTATACCACTGTTTGAATGGGTGGGGAGGAACGACTACCAGAAATAAAAGTACTTGGA
TCTTCTGCCCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001164744 ⟹ NP_001158216

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	4,823,166 - 4,826,538 (+)	NCBI
Rnor_6.0	20	3,819,416 - 3,822,788 (-)	NCBI
Rnor_5.0	20	5,898,747 - 5,902,119 (-)	NCBI
RGSC_v3.4	20	4,961,280 - 4,964,652 (+)	RGD
Celera	20	6,423,351 - 6,426,723 (+)	RGD

Sequence:

show sequence

GCGGGAGCTTGAGGCGCGAGTGCCACGTCCCAGCAAACCGAGAACGGAGAGGATCCCGGAGCCG
CGTGATGGCCAGGGTCCTGCGGGACCCCCACTGGGTGGCTGTGGGACTGCTGACCTGGGCAGCT
TTGGGGCTGCTGGTAGCCGGACACGAGGGTCATGGTGACCTGCACAGAGACGTGGAAGAGGACT
TCCATGGCCACAGCCACGGACACTCACATGAAGATTTCCACCATGGCCACAGCCATGGCCATGG
CCACACTCATGAGAGCATCTGGCATGGGCATGCCCACAGCCACGACCATGGACATTCACGGGAG
GATGTGCACCATGGCCATAGCCATGGCCACTCCCACGATAGCCTCCACCACAGAGGACATGGAC
ATAGCCATGGAGCCTCTAGGGAGGCTGGGGCTCCAGGCATCAAGCACCACCTGGACACTGTCAC
CCTCTGGGCCTATGCACTGGGGGCCACAGTGCTAATCTCCGCGGCTCCCTTCTTCGTGCTCTTC
CTCATCCCTGTGGAGTCAAACTCTCCCAGGCATCGTTCTCTGCTCCAGATCCTGCTCAGTTTTG
CTTCTGGGGGGCTCCTGGGAGATGCCTTCCTCCACCTCATCCCTCACGCCTTGGAACCTCATTC
GCACGATACTCCGGCACAGCCTGGCCACGGACACTCCCACAGCGGCCAGGGCCCCATTCTCTCT
GTGGGGCTGTGGGTTCTCAGTGGGATTGTCGCCTTTCTTGTGGTGGAGAAGTTTGTGAGACACG
TGAAAGGAGGGCACGGACACGCGCACGCGCACGGACACGGACACTCGCACGGAGACAGCCACGC
GCACGGACACAGCCACGCACACGGGGATAGGCATGAGTGTCCTTCAAAGGGAAAGCCCAGTTCA
GAGGATGAAAAGGAAGCAGGGGGCTTGCGGAAAAGGAGAGGAGGAGACACGGGGCCCAGAGATG
GCCCTCTGAAACCTCAGAACCCTGAAGAAGAAAAAACAGGCTCAGACCTGCGTGTGTCTGGGTA
CCTGAATCTGGCTGCTGACTTGGCACACAACTTCACAGACGGGCTGGCCATTGGTGCTTCCTTC
CGTGGGGGCCGAGGGCTTGGGATCCTGACCACGATGACAGTCCTGCTGCATGAAGTGCCTCATG
AGGTTGGGGACTTTGCCATCTTGGTCCAGTCTGGCTGCAGCAAGAAACAGGCGATGCGTCTGCA
ACTCTTGACTGCAATTGGAGCATTGGCAGGCACAGCCTGTGCCCTTCTCACTGAGGGAGGGGCA
GTGGGCAGTGAGGTGGCTGGTGGTGCAGGTCCCGGCTGGGTTCTGCCATTCACTGCAGGTGGAT
TCATCTATGTGGCAACAGTGTCCGTGCTACCTGAGCTACTGAGAGAGGCATCCCCGTTACAGTC
TCTCTTGGAGGTGCTGGGGCTGCTGGGGGGCGTTGCCATGATGGTACTGATTGCCCATCTTGAG
TGAGGGGTGGGTGACCTGTCCTACCCCTAACTCCAAAATAAAGGCAGTTGGGACCCTGGCCAGT
GCATTGTCAGGAGGCTCAGCCTGGAGAATGGCATCTTTGGTATTTGAGGCCTTAGAGGTATGAG
AGTCACACAGAGCATGAGAGGCCAGAGGGACCATGCTGTGGGAGACAGCCCAGCAGTGTTGTTG
GTTTTGGAGAAATAAATGGGACCATGAAGAAGGCTGGGAGACAGTAGCCTACCTGGTGGTCCCT
AGTCTACGTTTTCCCAGCACCAGCATGCCACACAAGGGTCCTCCAAGGTCCATCTCCCTCTGAA
CTGGTTAGTGATGGCTTCAGGGAAGGCCTGGCAGAAGGACTGGGGTAGACATCAATCGTGTGTC
CTGATTTGAGGGGGTGGGTGGTGTTCCTTGGAAAAATGTCATGGCCTGATTTTTGTTTCTACTC
ATTTTATACCACTGTTTGAATGGGTGGGGAGGAACGACTACCAGAAATAAAAGTACTTGGATCT
TCTGCCCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAA

hide sequence

RefSeq Acc Id:

XM_039098503 ⟹ XP_038954431

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	4,823,178 - 4,826,538 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001008885	(Get FASTA)	NCBI Sequence Viewer
	NP_001158216	(Get FASTA)	NCBI Sequence Viewer
	XP_038954431	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79141	(Get FASTA)	NCBI Sequence Viewer
	CAE83932	(Get FASTA)	NCBI Sequence Viewer
	EDL96824	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001008885 ⟸ NM_001008885
- Peptide Label:	precursor
- UniProtKB:	Q6MGB4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARVLRDPHWVAVGLLTWAALGLLVAGHEGHGDLHRDVEEDFHGHSHGHSHEDFHHGHSHGHGH THESIWHGHAHSHDHGHSREDVHHGHSHGHSHDSLHHRGHGHSHGASREAGAPGIKHHLDTVTL WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSH DTPAQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHAHAHGHGHSHGDSHAH GHSHAHGDRHECPSKGKPSSEDEKEAGGLRKRRGGDTGPRDGPLKPQNPEEEKTGSDLRVSGYL NLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQL LTAIGALAGTACALLTEGGAVGSEVAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSL LEVLGLLGGVAMMVLIAHLE hide sequence

RefSeq Acc Id:	NP_001158216 ⟸ NM_001164744
- Peptide Label:	precursor
- UniProtKB:	Q6MGB4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARVLRDPHWVAVGLLTWAALGLLVAGHEGHGDLHRDVEEDFHGHSHGHSHEDFHHGHSHGHGH THESIWHGHAHSHDHGHSREDVHHGHSHGHSHDSLHHRGHGHSHGASREAGAPGIKHHLDTVTL WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSH DTPAQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHAHAHGHGHSHGDSHAH GHSHAHGDRHECPSKGKPSSEDEKEAGGLRKRRGGDTGPRDGPLKPQNPEEEKTGSDLRVSGYL NLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQL LTAIGALAGTACALLTEGGAVGSEVAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSL LEVLGLLGGVAMMVLIAHLE hide sequence

RefSeq Acc Id:

ENSRNOP00000000541 ⟸ ENSRNOT00000000541

RefSeq Acc Id:

ENSRNOP00000071707 ⟸ ENSRNOT00000077357

RefSeq Acc Id:	XP_038954431 ⟸ XM_039098503
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6MGB4-F1-model_v2	AlphaFold	Q6MGB4	1-468	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701316

Promoter ID:

EPDNEW_R11840

Type:

initiation region

Name:

Slc39a7_1

Description:

solute carrier family 39 member 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	3,822,754 - 3,822,814	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1593280	AgrOrtholog
BioCyc Gene	G2FUF-4542	BioCyc
Ensembl Genes	ENSRNOG00000000465	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000000541	ENTREZGENE
	ENSRNOP00000000541.4	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000000541	ENTREZGENE
	ENSRNOT00000000541.7	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7127902	IMAGE-MGC_LOAD
InterPro	ZIP	UniProtKB/TrEMBL
KEGG Report	rno:294281	UniProtKB/TrEMBL
MGC_CLONE	MGC:94153	IMAGE-MGC_LOAD
NCBI Gene	294281	ENTREZGENE
PANTHER	ZINC TRANSPORTER SLC39A7	UniProtKB/TrEMBL
	ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4	UniProtKB/TrEMBL
Pfam	Zip	UniProtKB/TrEMBL
PhenoGen	Slc39a7	PhenoGen
UniProt	F7EQL7_RAT	UniProtKB/TrEMBL
	Q6MGB4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-24	Slc39a7	solute carrier family 39 member 7	Slc39a7	solute carrier family 39 (zinc transporter), member 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Slc39a7	solute carrier family 39 (zinc transporter), member 7	RT1-Ke4	RT1 class I, locus Ke4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2007-04-12	RT1-Ke4	RT1 class I, locus Ke4	RT1-Ke4_mapped	RT1 class I, locus Ke4 (mapped)	Data Merged	737654	APPROVED
2006-11-20	RT1-Ke4_mapped	RT1 class I, locus Ke4(mapped)	RT1-Ke4	RT1 class I, locus Ke4	Symbol set to symbol_mapped, name set to name (mapped)	1582166	APPROVED
2006-11-20	RT1-Ke4	RT1 class I, locus Ke4			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-02-11	RT1-Ke4	RT1 class I, locus Ke4	Rt1Ke4	RT1 region expressed gene KE4	Symbol and Name updated	625702	APPROVED
2003-04-09	Rt1Ke4	RT1 region expressed gene KE4	RT1-Ke4	Histidine-rich membrane protein	Symbol and Name updated	629477	APPROVED
2002-06-10	RT1-Ke4	Histidine-rich membrane protein			Symbol and Name status set to approved	70586	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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