Hsd3b3 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Hsd3b3 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3) Rattus norvegicus
Analyze
Symbol: Hsd3b3
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
RGD ID: 1592771
Description: Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in C21-steroid hormone metabolic process and steroid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane and mitochondrial membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2); INTERACTS WITH alpha-Zearalanol; bis(2-ethylhexyl) phthalate; Butylbenzyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II; 3 beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type 3; 3 beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type II; 3-beta-HSD II; Hsd3b
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82188,826,756 - 188,832,734 (-)NCBIGRCr8
mRatBN7.22186,138,044 - 186,144,024 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2186,138,044 - 186,144,033 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2193,787,719 - 193,793,697 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02191,589,811 - 191,595,789 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02186,420,289 - 186,426,267 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02200,756,557 - 200,762,492 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2200,585,748 - 200,762,492 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02220,223,664 - 220,229,494 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42193,387,391 - 193,388,559 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2178,614,103 - 178,620,081 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1944305   PMID:1985917   PMID:2243100   PMID:12865426   PMID:19698287  


Genomics

Comparative Map Data
Hsd3b3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82188,826,756 - 188,832,734 (-)NCBIGRCr8
mRatBN7.22186,138,044 - 186,144,024 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2186,138,044 - 186,144,033 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2193,787,719 - 193,793,697 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02191,589,811 - 191,595,789 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02186,420,289 - 186,426,267 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02200,756,557 - 200,762,492 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2200,585,748 - 200,762,492 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02220,223,664 - 220,229,494 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42193,387,391 - 193,388,559 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2178,614,103 - 178,620,081 (-)NCBICelera
Cytogenetic Map2q34NCBI
Hsd3b3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39398,648,792 - 98,672,465 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl398,648,839 - 98,670,443 (-)EnsemblGRCm39 Ensembl
GRCm38398,741,476 - 98,764,540 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl398,741,523 - 98,763,127 (-)EnsemblGRCm38mm10GRCm38
MGSCv37398,545,399 - 98,567,051 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36398,870,584 - 98,891,471 (-)NCBIMGSCv36mm8
Celera3100,077,484 - 100,099,855 (-)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map342.86NCBI

Variants

.
Variants in Hsd3b3
114 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2184114274202447032Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2185876309219753474Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
7488929Bp366Blood pressure QTL 3660.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2184974550193094998Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat

Markers in Region
RH128688  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22186,169,892 - 186,170,042 (+)MAPPERmRatBN7.2
Rnor_6.02200,756,587 - 200,756,736NCBIRnor6.0
Rnor_5.02220,223,694 - 220,223,843UniSTSRnor5.0
RGSC_v3.42193,500,945 - 193,501,094UniSTSRGSC3.4
Celera2178,651,862 - 178,652,011UniSTS
RH 3.4 Map21261.2UniSTS
Cytogenetic Map2q34UniSTS
RH139877  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22186,139,789 - 186,139,977 (+)MAPPERmRatBN7.2
mRatBN7.22186,171,600 - 186,171,788 (+)MAPPERmRatBN7.2
Rnor_6.02200,758,285 - 200,758,472NCBIRnor6.0
Rnor_5.02220,225,287 - 220,225,474UniSTSRnor5.0
RGSC_v3.42193,502,653 - 193,502,840UniSTSRGSC3.4
Celera2178,653,570 - 178,653,757UniSTS
Celera2178,615,849 - 178,616,036UniSTS
RH 3.4 Map21261.2UniSTS
Cytogenetic Map2q34UniSTS
UniSTS:256890  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.02221,794,793 - 221,795,078NCBIRnor5.0
RGSC_v3.42193,387,957 - 193,388,408UniSTSRGSC3.4
Celera2178,614,669 - 178,615,120UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 8 18 66 73 69 41 22 41 6 149 60 46 32 60 28

Sequence


Ensembl Acc Id: ENSRNOT00000056172   ⟹   ENSRNOP00000053018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2186,138,044 - 186,144,033 (-)Ensembl
Rnor_6.0 Ensembl2200,681,180 - 200,762,492 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000068511   ⟹   ENSRNOP00000062582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2200,585,748 - 200,762,206 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086835   ⟹   ENSRNOP00000075324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2200,756,898 - 200,762,206 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105757   ⟹   ENSRNOP00000095326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2186,138,044 - 186,143,738 (-)Ensembl
RefSeq Acc Id: NM_001042619   ⟹   NP_001036084
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82188,826,756 - 188,832,734 (-)NCBI
mRatBN7.22186,138,044 - 186,144,024 (-)NCBI
Rnor_6.02200,756,557 - 200,762,492 (-)NCBI
Rnor_5.02220,223,664 - 220,229,494 (-)NCBI
RGSC_v3.42193,387,391 - 193,388,559 (-)RGD
Celera2178,614,103 - 178,620,081 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001036084 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA63475 (Get FASTA)   NCBI Sequence Viewer  
  EDL85559 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000053018.4
  ENSRNOP00000075324
  ENSRNOP00000095326.1
  ENSRNOP00055046843
  ENSRNOP00060018795
  ENSRNOP00065043952
GenBank Protein P22072 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001036084   ⟸   NM_001042619
- UniProtKB: P22072 (UniProtKB/Swiss-Prot),   A6K3E1 (UniProtKB/TrEMBL),   A0A8I6AMF0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000062582   ⟸   ENSRNOT00000068511
Ensembl Acc Id: ENSRNOP00000053018   ⟸   ENSRNOT00000056172
Ensembl Acc Id: ENSRNOP00000075324   ⟸   ENSRNOT00000086835
Ensembl Acc Id: ENSRNOP00000095326   ⟸   ENSRNOT00000105757
Protein Domains
3-beta hydroxysteroid dehydrogenase/isomerase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P22072-F1-model_v2 AlphaFold P22072 1-373 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691605
Promoter ID:EPDNEW_R2127
Type:single initiation site
Name:Hsd3b3_1
Description:hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02200,762,452 - 200,762,512EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1592771 AgrOrtholog
BioCyc Gene G2FUF-51908 BioCyc
Ensembl Genes ENSRNOG00000042884 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000063905 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055032809 UniProtKB/Swiss-Prot
  ENSRNOG00060013844 UniProtKB/Swiss-Prot
  ENSRNOG00065031015 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000056172.5 UniProtKB/Swiss-Prot
  ENSRNOT00000086835 UniProtKB/TrEMBL
  ENSRNOT00000105757.1 UniProtKB/TrEMBL
  ENSRNOT00055056738 UniProtKB/Swiss-Prot
  ENSRNOT00060023643 UniProtKB/Swiss-Prot
  ENSRNOT00065053465 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 3Beta_OHSteriod_DH/Estase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipid_A_modif_metabolic_enz UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:682974 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 682974 ENTREZGENE
PANTHER BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPIMERASE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 3Beta_HSD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hsd3b3 PhenoGen
RatGTEx ENSRNOG00000042884 RatGTEx
  ENSRNOG00000063905 RatGTEx
  ENSRNOG00055032809 RatGTEx
  ENSRNOG00060013844 RatGTEx
  ENSRNOG00065031015 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 3BHS2_RAT UniProtKB/Swiss-Prot
  A0A0G2KAA4_RAT UniProtKB/TrEMBL
  A0A8I6AMF0 ENTREZGENE, UniProtKB/TrEMBL
  A6K3E1 ENTREZGENE, UniProtKB/TrEMBL
  P22072 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-18 Hsd3b3  hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3  Hsd3b3  3 beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type 3  Name changed 629549 APPROVED
2015-08-18 Hsd3b3  3 beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type 3  Hsd3b  3 beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type II  Name and Symbol changed 629549 APPROVED