LOC685590 (similar to Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase p110 subunit alpha) (PtdIns-3-kinase p110) (PI3K)) - Rat Genome Database

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Gene: LOC685590 (similar to Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase p110 subunit alpha) (PtdIns-3-kinase p110) (PI3K)) Rattus norvegicus
Analyze
Symbol: LOC685590 (Ensembl: AABR07037536.1)
Name: similar to Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase p110 subunit alpha) (PtdIns-3-kinase p110) (PI3K)
RGD ID: 1592558
Description:
Type: protein-coding
RefSeq Status: WITHDRAWN
Previously known as: LOC685637; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X23,243,126 - 23,254,011 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX23,243,470 - 23,246,719 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X23,655,176 - 23,711,281 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,988,917 - 42,016,182 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX21,845,379 - 21,858,025 (-)NCBICelera
Cytogenetic MapXq13NCBI


References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Markers in Region
BF387996  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X21,585,711 - 21,586,020 (-)MAPPERmRatBN7.2
mRatBN7.27130,130,756 - 130,131,074 (+)MAPPERmRatBN7.2
Rnor_6.07140,654,826 - 140,655,142NCBIRnor6.0
Rnor_6.0X23,266,948 - 23,267,256NCBIRnor6.0
Rnor_5.0X23,676,450 - 23,676,758UniSTSRnor5.0
Rnor_5.0X115,161,397 - 115,161,713UniSTSRnor5.0
RGSC_v3.4X42,011,506 - 42,011,814UniSTSRGSC3.4
RGSC_v3.47137,746,951 - 137,747,267UniSTSRGSC3.4
Celera7126,615,925 - 126,616,241UniSTS
CeleraX21,868,571 - 21,868,879UniSTS
Cytogenetic MapXq21UniSTS
RH141610  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22115,246,391 - 115,246,594 (-)MAPPERmRatBN7.2
mRatBN7.22115,246,391 - 115,246,594 (+)MAPPERmRatBN7.2
Rnor_6.02118,858,839 - 118,859,041NCBIRnor6.0
Rnor_6.0X23,242,695 - 23,242,897NCBIRnor6.0
Rnor_5.02138,519,317 - 138,519,519UniSTSRnor5.0
Rnor_5.0X23,654,956 - 23,655,158UniSTSRnor5.0
RGSC_v3.4X41,988,145 - 41,988,347UniSTSRGSC3.4
RGSC_v3.42118,669,799 - 118,670,001UniSTSRGSC3.4
Celera2110,357,434 - 110,357,636UniSTS
CeleraX21,844,948 - 21,845,150UniSTS
Cytogenetic MapXq21UniSTS
Cytogenetic Map2q25UniSTS
UniSTS:257082  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X23,245,316 - 23,245,841NCBIRnor6.0
Rnor_5.0X23,657,577 - 23,658,102UniSTSRnor5.0
RGSC_v3.4X41,990,766 - 41,991,291UniSTSRGSC3.4
CeleraX21,847,568 - 21,848,093UniSTS
Cytogenetic MapXq21UniSTS
Cytogenetic Map2q25UniSTS
UniSTS:257083  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X23,244,005 - 23,244,413NCBIRnor6.0
Rnor_5.0X23,656,266 - 23,656,674UniSTSRnor5.0
RGSC_v3.4X41,989,455 - 41,989,863UniSTSRGSC3.4
CeleraX21,846,257 - 21,846,665UniSTS
Cytogenetic MapXq21UniSTS
Cytogenetic Map2q25UniSTS
UniSTS:257081  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22115,218,994 - 115,219,253 (-)MAPPERmRatBN7.2
mRatBN7.22115,218,994 - 115,219,253 (+)MAPPERmRatBN7.2
Rnor_6.0X23,246,386 - 23,246,644NCBIRnor6.0
Rnor_6.02118,831,425 - 118,831,683NCBIRnor6.0
Rnor_5.0X23,658,647 - 23,658,905UniSTSRnor5.0
Rnor_5.02138,492,042 - 138,492,300UniSTSRnor5.0
Celera2110,329,936 - 110,330,194UniSTS
CeleraX21,848,638 - 21,848,896UniSTS
Cytogenetic Map2q25UniSTS
Cytogenetic MapXq21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 2 10 18 5 17 5 4 6 51 23 24 11 4
Below cutoff 1 29 35 32 2 32 4 5 12 8 13 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_017588100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000085588   ⟹   ENSRNOP00000073549
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX23,243,470 - 23,246,719 (-)Ensembl
RefSeq Acc Id: XM_017588100   ⟹   XP_017443589
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,845,379 - 21,858,025 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017602181   ⟹   XP_017457670
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X23,243,126 - 23,254,011 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_017443589 (Get FASTA)   NCBI Sequence Viewer  
  XP_017457670 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_017443589   ⟸   XM_017588100
- Sequence:
RefSeq Acc Id: XP_017457670   ⟸   XM_017602181
- Sequence:
RefSeq Acc Id: ENSRNOP00000073549   ⟸   ENSRNOT00000085588

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K5T3-F1-model_v2 AlphaFold A0A0G2K5T3 1-1063 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSRNOG00000056810 Ensembl
NCBI Gene 685590 ENTREZGENE
PhenoGen LOC685590 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 LOC685590  similar to Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase p110 subunit alpha) (PtdIns-3-kinase p110) (PI3K)  LOC685637  similar to Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase p110 subunit alpha) (PtdIns-3-kinase p110) (PI3K)  Data Merged 737654 PROVISIONAL
2006-11-20 LOC685590  similar to Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase p110 subunit alpha) (PtdIns-3-kinase p110) (PI3K)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC685637  similar to Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase p110 subunit alpha) (PtdIns-3-kinase p110) (PI3K)      Symbol and Name status set to provisional 70820 PROVISIONAL