Garem1 (GRB2 associated regulator of MAPK1 subtype 1)

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Gene: Garem1 (GRB2 associated regulator of MAPK1 subtype 1) Rattus norvegicus

Analyze

Symbol:

Garem1

Name:

GRB2 associated regulator of MAPK1 subtype 1

RGD ID:

1591842

Description:

Predicted to enable proline-rich region binding activity. Predicted to be involved in several processes, including cellular response to epidermal growth factor stimulus; epidermal growth factor receptor signaling pathway; and positive regulation of ERK1 and ERK2 cascade. Orthologous to human GAREM1 (GRB2 associated regulator of MAPK1 subtype 1); INTERACTS WITH amphetamine; bisphenol A; tetrachloromethane.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Garem; GRB2 associated regulator of MAPK1, member 1; GRB2 associated, regulator of MAPK1; GRB2-associated and regulator of MAPK protein 1; GRB2-associated and regulator of MAPK protein-like; LOC498827; LOC679154; RGD1562080; similar to DNA-directed RNA polymerase II largest subunit (RPB1); similar to Hypothetical protein CBG10141

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	12,420,169 - 12,585,323 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	12,423,882 - 12,585,345 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	18	14,982,604 - 15,007,245 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	12,224,514 - 12,284,188 (-)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	18	12,224,514 - 12,284,188 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	14,769,102 - 14,791,523 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	12,944,256 - 12,946,270 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	18	12,415,517 - 12,519,188 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

ciguatoxin CTX1B (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

doxorubicin (ISO)

fonofos (ISO)

formaldehyde (ISO)

hydrogen peroxide (ISO)

hydroquinone O-beta-D-glucopyranoside (ISO)

lead(0) (ISO)

leflunomide (ISO)

lipopolysaccharide (ISO)

melphalan (ISO)

paracetamol (ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

quercetin (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

terbufos (ISO)

tetrachloromethane (EXP)

thimerosal (ISO)

urethane (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to epidermal growth factor stimulus (ISO)

epidermal growth factor receptor signaling pathway (ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

Molecular Function

proline-rich region binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:19509291	PMID:24003223

Genomics

Comparative Map Data

Garem1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	12,420,169 - 12,585,323 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	12,423,882 - 12,585,345 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	18	14,982,604 - 15,007,245 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	12,224,514 - 12,284,188 (-)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	18	12,224,514 - 12,284,188 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	14,769,102 - 14,791,523 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	12,944,256 - 12,946,270 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	18	12,415,517 - 12,519,188 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

GAREM1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	32,263,522 - 32,470,882 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	32,124,877 - 32,470,882 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	29,843,485 - 30,050,845 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	28,101,461 - 28,304,445 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	28,101,474 - 28,304,445	NCBI
Celera	18	26,654,417 - 26,857,408 (-)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI
HuRef	18	26,700,077 - 26,907,135 (-)	NCBI		HuRef
CHM1_1	18	29,770,990 - 29,977,911 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	32,453,815 - 32,661,186 (-)	NCBI		T2T-CHM13v2.0

Garem1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	21,260,399 - 21,433,196 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	21,260,258 - 21,433,195 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	21,127,342 - 21,300,139 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	21,127,201 - 21,300,138 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	21,285,843 - 21,458,640 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	21,270,211 - 21,443,148 (-)	NCBI		MGSCv36	mm8
Celera	18	21,623,035 - 21,796,413 (-)	NCBI		Celera
Cytogenetic Map	18	A2	NCBI
cM Map	18	11.87	NCBI

Garem1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	19,469,649 - 19,663,654 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	19,469,652 - 19,663,654 (-)	NCBI	ChiLan1.0	ChiLan1.0

GAREM1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	18	35,332,057 - 35,540,119 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	25,470,702 - 25,678,146 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	29,065,053 - 29,272,225 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	29,065,053 - 29,272,231 (-)	Ensembl	panpan1.1		panPan2

GAREM1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	57,158,005 - 57,423,643 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	57,295,070 - 57,419,252 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	56,654,442 - 56,856,713 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	57,196,399 - 57,404,576 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	57,195,979 - 57,400,589 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	56,881,075 - 57,082,118 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	56,898,894 - 57,100,606 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	57,195,790 - 57,397,330 (+)	NCBI		UU_Cfam_GSD_1.0

Garem1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	52,926,545 - 53,066,880 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936682	947,487 - 1,068,482 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936682	947,420 - 1,068,468 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GAREM1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	116,100,372 - 116,325,133 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	116,100,371 - 116,324,853 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	108,838,673 - 109,028,414 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GAREM1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	48,287,589 - 48,483,135 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	48,287,579 - 48,483,552 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	22,837,054 - 23,033,716 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Garem1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624770	500,641 - 728,014 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624770	501,113 - 727,736 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Garem1
947 total Variants

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552968	Pigfal19	Plasma insulin-like growth factor 1 level QTL 19	11.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	18	1	25758124	Rat
9590248	Scort10	Serum corticosterone level QTL 10	19.71	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	1	25758124	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	30558703	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34291613	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34291613	Rat
61388	Bp2	Blood pressure QTL 2	3.23		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	1	35374722	Rat
9589153	Insul31	Insulin level QTL 31	7.15	0.05	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	18	1	42547119	Rat
1641910	Colcr3	Colorectal carcinoma resistance QTL 3	5.02	0.000007	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor surface area measurement (CMO:0002078)	18	2249477	22066430	Rat
1641910	Colcr3	Colorectal carcinoma resistance QTL 3	5.02	0.000007	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	2249477	22066430	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4207941	60377792	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5185858	40503530	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11941791	31393320	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	11941791	31393320	Rat
12904690	Cm129	Cardiac mass QTL 129		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	11944273	26548295	Rat
12904689	Cm128	Cardiac mass QTL 128		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	11944273	26548295	Rat
12904693	Am20	Aortic mass QTL 20		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	11944273	26548295	Rat
12904695	Kidm73	Kidney mass QTL 73		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	11944273	26548295	Rat
12904691	Cm130	Cardiac mass QTL 130		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	11944273	26548295	Rat
12904680	Bw189	Body weight QTL 189		0.019	body mass (VT:0001259)	body weight (CMO:0000012)	18	11944273	26548295	Rat
2301410	Bp317	Blood pressure QTL 317		0.004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944273	26548295	Rat
1331781	Scl28	Serum cholesterol level QTL 28	3.995		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	11944299	24797117	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944299	31359530	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	11944299	41122201	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944299	52293055	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	11944299	59330563	Rat
6903359	Bp355	Blood pressure QTL 355	3.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944544	59796478	Rat
70178	Eaez	Experimental allergic encephalomyelitis QTL z	2.4		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	18	12357786	12874620	Rat

Markers in Region

AU047296

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	12,454,210 - 12,454,409 (-)	MAPPER	mRatBN7.2
Rnor_6.0	18	14,992,080 - 14,992,278	NCBI	Rnor6.0
Rnor_5.0	18	14,776,706 - 14,776,904	UniSTS	Rnor5.0
Celera	18	12,445,611 - 12,445,809	UniSTS

WI-14403

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	12,423,905 - 12,424,053 (-)	MAPPER	mRatBN7.2
Rnor_6.0	18	15,032,610 - 15,032,757	NCBI	Rnor6.0
Rnor_5.0	18	14,816,887 - 14,817,034	UniSTS	Rnor5.0
Celera	18	12,415,280 - 12,415,427	UniSTS

AU049676

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	12,442,334 - 12,442,576 (-)	MAPPER	mRatBN7.2
Rnor_6.0	18	15,007,872 - 15,008,113	NCBI	Rnor6.0
Rnor_6.0	18	15,014,688 - 15,014,929	NCBI	Rnor6.0
Rnor_5.0	18	14,799,314 - 14,799,555	UniSTS	Rnor5.0
Rnor_5.0	18	14,792,498 - 14,792,739	UniSTS	Rnor5.0
Celera	18	12,433,735 - 12,433,976	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_006254485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC082035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC098708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000083236

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	18	12,224,514 - 12,284,188 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000095044 ⟹ ENSRNOP00000089678

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	12,423,882 - 12,549,791 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000100631 ⟹ ENSRNOP00000087833

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	12,423,882 - 12,585,345 (-)	Ensembl

RefSeq Acc Id:

XM_039097346 ⟹ XP_038953274

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	18	12,420,169 - 12,585,323 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_038953274	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_038953274 ⟸ XM_039097346
- UniProtKB:	A0A8I6AHF4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000087833 ⟸ ENSRNOT00000100631

RefSeq Acc Id:

ENSRNOP00000089678 ⟸ ENSRNOT00000095044

Protein Domains

CABIT

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1591842	AgrOrtholog
BioCyc Gene	G2FUF-8203	BioCyc
Ensembl Genes	ENSRNOG00000060341	Ensembl
	ENSRNOG00000062552	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000087833	ENTREZGENE
	ENSRNOP00000087833.1	UniProtKB/TrEMBL
	ENSRNOP00000089678.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000095044.1	UniProtKB/TrEMBL
	ENSRNOT00000100631	ENTREZGENE
	ENSRNOT00000100631.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.150.50	UniProtKB/TrEMBL
InterPro	CABIT_dom	UniProtKB/TrEMBL
	SAM/pointed_sf	UniProtKB/TrEMBL
NCBI Gene	679154	ENTREZGENE
PANTHER	GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 1	UniProtKB/TrEMBL
	GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER	UniProtKB/TrEMBL
Pfam	CABIT	UniProtKB/TrEMBL
PhenoGen	Garem1	PhenoGen
Superfamily-SCOP	SSF47769	UniProtKB/TrEMBL
UniProt	A0A8I6AC94_RAT	UniProtKB/TrEMBL
	A0A8I6AHF4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Garem1	GRB2 associated regulator of MAPK1 subtype 1	Garem1	GRB2 associated regulator of MAPK1 subtype 1	Data Merged	737654	PROVISIONAL
2021-08-09	Garem1	GRB2 associated regulator of MAPK1 subtype 1			Symbol and Name status set to provisional	45752	PROVISIONAL
2021-03-09	Garem1	GRB2 associated regulator of MAPK1 subtype 1	RGD1562080	similar to Hypothetical protein CBG10141	Data Merged	737654	PROVISIONAL
2016-11-14	Garem1	GRB2 associated regulator of MAPK1 subtype 1	Garem1	GRB2 associated regulator of MAPK1, member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-11-12	Garem1	GRB2 associated regulator of MAPK1, member 1	Garem	GRB2 associated, regulator of MAPK1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-09	Garem	GRB2 associated, regulator of MAPK1	LOC679154	similar to DNA-directed RNA polymerase II largest subunit (RPB1)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1562080	similar to Hypothetical protein CBG10141	RGD1562080_predicted	similar to Hypothetical protein CBG10141 (predicted)	'predicted' is removed	2292626	APPROVED
2006-11-20	LOC679154	similar to DNA-directed RNA polymerase II largest subunit (RPB1)			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-07	RGD1562080_predicted	similar to Hypothetical protein CBG10141 (predicted)	LOC498827	similar to Hypothetical protein CBG10141	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC498827	similar to Hypothetical protein CBG10141			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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