Macrod2 (mono-ADP ribosylhydrolase 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Macrod2 (mono-ADP ribosylhydrolase 2) Rattus norvegicus
Analyze
Symbol: Macrod2
Name: mono-ADP ribosylhydrolase 2
RGD ID: 1591318
Description: Predicted to enable ADP-ribosylglutamate hydrolase activity and deacetylase activity. Predicted to be involved in several processes, including DNA damage response; peptidyl-glutamate ADP-deribosylation; and purine nucleoside metabolic process. Predicted to act upstream of or within response to bacterium. Predicted to be located in nucleolus. Predicted to be active in nucleoplasm. Orthologous to human MACROD2 (mono-ADP ribosylhydrolase 2); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07054000.1; ADP-ribose glycohydrolase MACROD2; LOC102548740; LOC685695; MACRO domain containing 2; O-acetyl-ADP-ribose deacetylase MACROD2; similar to LRP16 protein; similar to SON protein; uncharacterized LOC102548740
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83148,173,821 - 150,191,077 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3148,173,829 - 150,188,058 (+)EnsemblGRCr8
mRatBN7.23127,720,066 - 129,737,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,720,181 - 129,734,492 (+)EnsemblmRatBN7.2
Rnor_6.03135,729,839 - 136,422,082 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3134,413,170 - 134,441,540 (+)NCBIrn6Rnor6.0
Rnor_5.03140,866,319 - 142,867,324 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43128,570,984 - 130,673,729 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3127,663,937 - 128,671,039 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IEA,ISO)
nucleoplasm  (IBA,IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation. Barkauskaite E, etal., Mol Cell. 2015 Jun 18;58(6):935-46. doi: 10.1016/j.molcel.2015.05.007.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:17586838   PMID:21257746   PMID:23012479   PMID:23474712   PMID:23474714  


Genomics

Comparative Map Data
Macrod2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83148,173,821 - 150,191,077 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3148,173,829 - 150,188,058 (+)EnsemblGRCr8
mRatBN7.23127,720,066 - 129,737,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,720,181 - 129,734,492 (+)EnsemblmRatBN7.2
Rnor_6.03135,729,839 - 136,422,082 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3134,413,170 - 134,441,540 (+)NCBIrn6Rnor6.0
Rnor_5.03140,866,319 - 142,867,324 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43128,570,984 - 130,673,729 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3127,663,937 - 128,671,039 (+)NCBICelera
Cytogenetic Map3q41NCBI
MACROD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382013,995,516 - 16,053,197 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2013,995,369 - 16,053,197 (+)Ensemblhg38GRCh38
GRCh372013,976,162 - 16,033,842 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362013,924,146 - 15,981,842 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342013,924,318 - 13,982,313NCBI
Celera2014,051,522 - 16,108,818 (+)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2013,936,352 - 15,994,332 (+)NCBIHuRef
CHM1_12013,976,154 - 16,033,759 (+)NCBICHM1_1
T2T-CHM13v2.02014,044,768 - 16,102,640 (+)NCBIT2T-CHM13v2.0
Macrod2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392140,237,223 - 142,234,886 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2140,237,229 - 142,234,886 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382140,395,303 - 142,392,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2140,395,309 - 142,392,966 (+)Ensemblmm10GRCm38
MGSCv372140,221,166 - 142,215,786 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362140,086,876 - 140,114,395 (+)NCBIMGSCv36mm8
Celera2141,585,472 - 143,579,729 (+)NCBICelera
Cytogenetic Map2F3- G1NCBI
cM Map269.2NCBI
Macrod2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541523,398,776 - 25,226,450 (+)Ensembl
ChiLan1.0NW_00495541523,398,409 - 25,239,184 (+)NCBIChiLan1.0ChiLan1.0
MACROD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22114,894,726 - 16,949,118 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12014,891,558 - 16,945,955 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02013,966,338 - 16,020,506 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12015,811,151 - 16,001,125 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2013,950,260 - 15,997,806 (+)EnsemblpanPan2panpan1.1
MACROD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1246,740,943 - 8,673,524 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl246,744,744 - 8,673,275 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha246,549,204 - 8,490,218 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0247,160,459 - 9,088,151 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl247,164,261 - 9,082,843 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1246,754,652 - 8,690,508 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0246,853,205 - 8,780,688 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0247,128,078 - 9,135,123 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Macrod2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640155,484,882 - 157,435,824 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364853,919,525 - 5,859,251 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364853,917,060 - 5,859,527 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MACROD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1722,635,284 - 24,683,549 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11722,635,105 - 24,686,846 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21727,211,780 - 27,690,646 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MACROD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1242,891,656 - 44,973,129 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660543,167,567 - 5,340,119 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Macrod2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474114,998,305 - 17,252,759 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474114,998,007 - 17,256,372 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Macrod2
12878 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:39
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000045312
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)384091273129091273Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat

Markers in Region
D3Rat106  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83148,532,210 - 148,532,442 (+)Marker Load Pipeline
mRatBN7.23128,078,584 - 128,078,816 (+)MAPPERmRatBN7.2
Rnor_6.03134,767,520 - 134,767,751NCBIRnor6.0
Rnor_5.03141,217,964 - 141,218,195UniSTSRnor5.0
RGSC_v3.43129,005,686 - 129,005,918RGDRGSC3.4
RGSC_v3.43129,005,687 - 129,005,918UniSTSRGSC3.4
Celera3126,704,181 - 126,704,412UniSTS
RGSC_v3.13128,911,259 - 128,911,491RGD
FHH x ACI Map380.25UniSTS
FHH x ACI Map380.25RGD
Cytogenetic Map3q41UniSTS
D3Rat129  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83148,283,196 - 148,283,355 (+)Marker Load Pipeline
mRatBN7.23127,829,560 - 127,829,719 (+)MAPPERmRatBN7.2
Rnor_6.03134,520,559 - 134,520,717NCBIRnor6.0
Rnor_5.03140,969,065 - 140,969,223UniSTSRnor5.0
Celera3126,457,069 - 126,457,227UniSTS
RH 3.4 Map31152.5RGD
RH 3.4 Map31152.5UniSTS
SHRSP x BN Map364.1499RGD
SHRSP x BN Map364.1499UniSTS
FHH x ACI Map380.25RGD
Cytogenetic Map3q41UniSTS
D3Rat253  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83149,412,814 - 149,413,062 (+)Marker Load Pipeline
mRatBN7.23128,959,229 - 128,959,477 (+)MAPPERmRatBN7.2
Rnor_6.03135,650,153 - 135,650,400NCBIRnor6.0
Rnor_5.03142,097,297 - 142,097,544UniSTSRnor5.0
RGSC_v3.43129,898,073 - 129,898,321RGDRGSC3.4
RGSC_v3.43129,898,074 - 129,898,321UniSTSRGSC3.4
Celera3127,581,938 - 127,582,185UniSTS
RGSC_v3.13129,803,647 - 129,803,894RGD
RH 3.4 Map31160.0UniSTS
RH 3.4 Map31160.0RGD
RH 2.0 Map3777.9RGD
SHRSP x BN Map362.4899RGD
Cytogenetic Map3q41UniSTS
D3Rat248  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83149,288,841 - 149,289,035 (+)Marker Load Pipeline
mRatBN7.23128,835,257 - 128,835,451 (+)MAPPERmRatBN7.2
Rnor_6.03135,525,641 - 135,525,834NCBIRnor6.0
Rnor_5.03141,972,911 - 141,973,104UniSTSRnor5.0
RGSC_v3.43129,771,711 - 129,771,907RGDRGSC3.4
RGSC_v3.43129,771,712 - 129,771,907UniSTSRGSC3.4
Celera3127,458,282 - 127,458,475UniSTS
RGSC_v3.13129,677,284 - 129,677,480RGD
SHRSP x BN Map364.1499UniSTS
SHRSP x BN Map364.1499RGD
Cytogenetic Map3q41UniSTS
D3Got96  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23128,078,672 - 128,078,873 (+)MAPPERmRatBN7.2
Rnor_6.03134,767,608 - 134,767,808NCBIRnor6.0
Rnor_5.03141,218,052 - 141,218,252UniSTSRnor5.0
RGSC_v3.43129,005,774 - 129,005,975RGDRGSC3.4
RGSC_v3.43129,005,775 - 129,005,975UniSTSRGSC3.4
Celera3126,704,269 - 126,704,469UniSTS
RGSC_v3.13128,911,348 - 128,911,548RGD
RH 3.4 Map31156.0UniSTS
RH 3.4 Map31156.0RGD
RH 2.0 Map3773.1RGD
Cytogenetic Map3q41UniSTS
D3Got95  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23128,344,077 - 128,344,236 (+)MAPPERmRatBN7.2
Rnor_6.03135,036,900 - 135,037,058NCBIRnor6.0
Rnor_5.03141,484,812 - 141,484,970UniSTSRnor5.0
RGSC_v3.43129,273,114 - 129,273,273RGDRGSC3.4
RGSC_v3.43129,273,115 - 129,273,273UniSTSRGSC3.4
Celera3126,966,947 - 126,967,105UniSTS
RGSC_v3.13129,178,688 - 129,178,846RGD
RH 3.4 Map31158.6UniSTS
RH 3.4 Map31158.6RGD
RH 2.0 Map3785.1RGD
Cytogenetic Map3q41UniSTS
D16S505  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21227,172,029 - 27,172,147 (+)MAPPERmRatBN7.2
mRatBN7.23129,052,956 - 129,053,750 (+)MAPPERmRatBN7.2
Rnor_6.03135,738,830 - 135,739,623NCBIRnor6.0
Rnor_6.01230,803,111 - 30,803,228NCBIRnor6.0
Rnor_5.01232,737,419 - 32,737,536UniSTSRnor5.0
Rnor_5.03142,185,974 - 142,186,767UniSTSRnor5.0
RGSC_v3.43129,992,101 - 129,992,894UniSTSRGSC3.4
RGSC_v3.41228,241,572 - 28,241,689UniSTSRGSC3.4
Celera1228,875,783 - 28,875,900UniSTS
Celera3127,675,514 - 127,676,307UniSTS
Cytogenetic Map3q41UniSTS
Cytogenetic Map12q13UniSTS
RH142697  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23128,023,928 - 128,024,050 (+)MAPPERmRatBN7.2
Rnor_6.03134,712,869 - 134,712,990NCBIRnor6.0
Rnor_5.03141,163,313 - 141,163,434UniSTSRnor5.0
RGSC_v3.43128,951,034 - 128,951,155UniSTSRGSC3.4
Celera3126,649,711 - 126,649,832UniSTS
RH 3.4 Map31153.5UniSTS
Cytogenetic Map3q41UniSTS
RH143948  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23128,797,553 - 128,797,661 (+)MAPPERmRatBN7.2
Rnor_6.03135,489,593 - 135,489,700NCBIRnor6.0
Rnor_5.03141,936,909 - 141,937,016UniSTSRnor5.0
RGSC_v3.43129,733,714 - 129,733,821UniSTSRGSC3.4
Celera3127,420,595 - 127,420,702UniSTS
RH 3.4 Map31158.3UniSTS
Cytogenetic Map3q41UniSTS
BF394114  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23128,947,899 - 128,948,078 (+)MAPPERmRatBN7.2
Rnor_6.03135,638,820 - 135,638,998NCBIRnor6.0
Rnor_5.03142,086,090 - 142,086,268UniSTSRnor5.0
RGSC_v3.43129,886,260 - 129,886,438UniSTSRGSC3.4
Celera3127,570,620 - 127,570,798UniSTS
RH 3.4 Map31158.9UniSTS
Cytogenetic Map3q41UniSTS
AU047257  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23129,037,682 - 129,037,820 (+)MAPPERmRatBN7.2
Rnor_6.03135,726,142 - 135,726,279NCBIRnor6.0
Rnor_5.03142,173,286 - 142,173,423UniSTSRnor5.0
RGSC_v3.43129,976,827 - 129,976,964UniSTSRGSC3.4
Celera3127,659,942 - 127,660,079UniSTS
Cytogenetic Map3q41UniSTS
RH138354  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23129,185,085 - 129,185,304 (+)MAPPERmRatBN7.2
Rnor_6.03135,871,065 - 135,871,283NCBIRnor6.0
Rnor_5.03142,318,073 - 142,318,291UniSTSRnor5.0
RGSC_v3.43130,123,977 - 130,124,195UniSTSRGSC3.4
Celera3127,807,338 - 127,807,556UniSTS
RH 3.4 Map31160.0UniSTS
Cytogenetic Map3q41UniSTS
BE101796  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23129,551,479 - 129,551,632 (+)MAPPERmRatBN7.2
Rnor_6.03136,234,979 - 136,235,131NCBIRnor6.0
Rnor_5.03142,681,891 - 142,682,043UniSTSRnor5.0
RGSC_v3.43130,505,997 - 130,506,149UniSTSRGSC3.4
Celera3128,491,147 - 128,491,299UniSTS
RH 3.4 Map31159.2UniSTS
Cytogenetic Map3q41UniSTS
AU048631  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23129,555,777 - 129,556,024 (+)MAPPERmRatBN7.2
Rnor_6.03136,239,277 - 136,239,523NCBIRnor6.0
Rnor_5.03142,686,189 - 142,686,435UniSTSRnor5.0
RGSC_v3.43130,510,295 - 130,510,541UniSTSRGSC3.4
Celera3128,495,435 - 128,495,681UniSTS
Cytogenetic Map3q41UniSTS
AU048934  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23127,940,309 - 127,940,463 (+)MAPPERmRatBN7.2
Rnor_6.03134,629,097 - 134,629,250NCBIRnor6.0
Rnor_5.03141,079,541 - 141,079,694UniSTSRnor5.0
RGSC_v3.43128,867,459 - 128,867,612UniSTSRGSC3.4
Celera3126,566,307 - 126,566,458UniSTS
Cytogenetic Map3q41UniSTS
AU049416  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23128,111,706 - 128,111,909 (+)MAPPERmRatBN7.2
Rnor_6.03134,800,631 - 134,800,833NCBIRnor6.0
Rnor_5.03141,251,075 - 141,251,277UniSTSRnor5.0
RGSC_v3.43129,039,360 - 129,039,562UniSTSRGSC3.4
Celera3126,738,036 - 126,738,238UniSTS
Cytogenetic Map3q41UniSTS
AFM349xe9  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23128,986,676 - 128,987,911 (+)MAPPERmRatBN7.2
Rnor_6.03135,677,500 - 135,678,734NCBIRnor6.0
Rnor_5.03142,124,644 - 142,125,878UniSTSRnor5.0
RGSC_v3.43129,925,521 - 129,926,755UniSTSRGSC3.4
Celera3127,609,385 - 127,610,619UniSTS
Cytogenetic Map3q41UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 3 26 89 24 158 68 20 98 83 49 43 43

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001428715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000072928   ⟹   ENSRNOP00000065981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3148,173,829 - 148,203,180 (+)Ensembl
mRatBN7.2 Ensembl3127,720,181 - 127,749,435 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000074338   ⟹   ENSRNOP00000066473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3148,173,855 - 150,182,649 (+)Ensembl
mRatBN7.2 Ensembl3127,720,292 - 127,780,172 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108469   ⟹   ENSRNOP00000083380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3148,173,855 - 148,282,669 (+)Ensembl
mRatBN7.2 Ensembl3127,720,181 - 128,053,146 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110287   ⟹   ENSRNOP00000096175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3148,173,855 - 150,182,649 (+)Ensembl
mRatBN7.2 Ensembl3127,720,203 - 127,830,266 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110455   ⟹   ENSRNOP00000078851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3148,173,855 - 150,188,058 (+)Ensembl
mRatBN7.2 Ensembl3127,720,181 - 129,734,492 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117007   ⟹   ENSRNOP00000084670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3148,173,855 - 150,182,649 (+)Ensembl
mRatBN7.2 Ensembl3127,720,181 - 129,729,083 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000167804   ⟹   ENSRNOP00000111455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3148,173,856 - 148,315,698 (+)Ensembl
RefSeq Acc Id: XM_039106853   ⟹   XP_038962781
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,821 - 150,191,077 (+)NCBI
mRatBN7.23127,720,071 - 129,737,511 (+)NCBI
RefSeq Acc Id: XM_039106854   ⟹   XP_038962782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,822 - 150,191,077 (+)NCBI
mRatBN7.23127,720,074 - 129,737,511 (+)NCBI
RefSeq Acc Id: XM_039106855   ⟹   XP_038962783
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,821 - 150,191,077 (+)NCBI
mRatBN7.23127,720,071 - 129,737,511 (+)NCBI
RefSeq Acc Id: XM_039106856   ⟹   XP_038962784
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,822 - 150,191,077 (+)NCBI
mRatBN7.23127,720,074 - 129,737,511 (+)NCBI
RefSeq Acc Id: XM_039106857   ⟹   XP_038962785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,821 - 150,191,077 (+)NCBI
mRatBN7.23127,720,066 - 129,737,511 (+)NCBI
RefSeq Acc Id: XM_039106858   ⟹   XP_038962786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,821 - 150,191,077 (+)NCBI
mRatBN7.23127,720,069 - 129,737,511 (+)NCBI
RefSeq Acc Id: XM_039106860   ⟹   XP_038962788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,823 - 150,016,859 (+)NCBI
mRatBN7.23127,720,077 - 129,567,763 (+)NCBI
RefSeq Acc Id: XM_039106861   ⟹   XP_038962789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83149,538,760 - 150,191,077 (+)NCBI
mRatBN7.23129,085,198 - 129,737,511 (+)NCBI
RefSeq Acc Id: XM_063284990   ⟹   XP_063141060
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,824 - 148,245,969 (+)NCBI
RefSeq Acc Id: XM_063284992   ⟹   XP_063141062
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,825 - 148,282,671 (+)NCBI
RefSeq Acc Id: XM_063284993   ⟹   XP_063141063
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,829 - 148,666,474 (+)NCBI
RefSeq Acc Id: XM_063284994   ⟹   XP_063141064
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,830 - 148,282,671 (+)NCBI
RefSeq Acc Id: XM_063284995   ⟹   XP_063141065
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,830 - 148,359,960 (+)NCBI
RefSeq Acc Id: XR_010064912
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,825 - 148,436,613 (+)NCBI
RefSeq Acc Id: XR_010064913
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,173,826 - 148,436,613 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001415644 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415645 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415646 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415647 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415648 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415649 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415650 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415651 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415652 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962781 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962782 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962783 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962784 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962785 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962786 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962788 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962789 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141060 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141062 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141063 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141064 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141065 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065981.2
  ENSRNOP00000066473
  ENSRNOP00000066473.3
  ENSRNOP00000078851.1
  ENSRNOP00000083380
  ENSRNOP00000083380.1
  ENSRNOP00000084670
  ENSRNOP00000084670.1
  ENSRNOP00000096175
  ENSRNOP00000096175.1
RefSeq Acc Id: XP_038962785   ⟸   XM_039106857
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZLS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962786   ⟸   XM_039106858
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZLS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962781   ⟸   XM_039106853
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZLS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962783   ⟸   XM_039106855
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038962782   ⟸   XM_039106854
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038962784   ⟸   XM_039106856
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038962788   ⟸   XM_039106860
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038962789   ⟸   XM_039106861
- Peptide Label: isoform X8
Ensembl Acc Id: ENSRNOP00000066473   ⟸   ENSRNOT00000074338
Ensembl Acc Id: ENSRNOP00000083380   ⟸   ENSRNOT00000108469
Ensembl Acc Id: ENSRNOP00000084670   ⟸   ENSRNOT00000117007
Ensembl Acc Id: ENSRNOP00000065981   ⟸   ENSRNOT00000072928
Ensembl Acc Id: ENSRNOP00000096175   ⟸   ENSRNOT00000110287
Ensembl Acc Id: ENSRNOP00000078851   ⟸   ENSRNOT00000110455
RefSeq Acc Id: XP_063141060   ⟸   XM_063284990
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063141062   ⟸   XM_063284992
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063141063   ⟸   XM_063284993
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063141065   ⟸   XM_063284995
- Peptide Label: isoform X13
- UniProtKB: M0RAC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141064   ⟸   XM_063284994
- Peptide Label: isoform X12
Ensembl Acc Id: ENSRNOP00000111455   ⟸   ENSRNOT00000167804
Protein Domains
Macro

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R921-F1-model_v2 AlphaFold M0R921 1-112 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591318 AgrOrtholog
BioCyc Gene G2FUF-47660 BioCyc
Ensembl Genes ENSRNOG00000050784 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072928.2 UniProtKB/TrEMBL
  ENSRNOT00000074338 ENTREZGENE
  ENSRNOT00000074338.3 UniProtKB/TrEMBL
  ENSRNOT00000108469 ENTREZGENE
  ENSRNOT00000108469.1 UniProtKB/TrEMBL
  ENSRNOT00000110287 ENTREZGENE
  ENSRNOT00000110287.1 UniProtKB/TrEMBL
  ENSRNOT00000110455.1 UniProtKB/TrEMBL
  ENSRNOT00000117007 ENTREZGENE
  ENSRNOT00000117007.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.220.10 UniProtKB/TrEMBL
InterPro Macro_dom UniProtKB/TrEMBL
  Macro_dom-like UniProtKB/TrEMBL
NCBI Gene 685695 ENTREZGENE
PANTHER ADP-RIBOSE GLYCOHYDROLASE MACROD2 UniProtKB/TrEMBL
  GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED UniProtKB/TrEMBL
Pfam Macro UniProtKB/TrEMBL
PhenoGen Macrod2 PhenoGen
PROSITE MACRO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050784 RatGTEx
SMART A1pp UniProtKB/TrEMBL
Superfamily-SCOP SSF52949 UniProtKB/TrEMBL
UniProt A0A8I5ZLS6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZWW6_RAT UniProtKB/TrEMBL
  A0A8I5ZYG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AUQ6 ENTREZGENE, UniProtKB/TrEMBL
  M0R921_RAT UniProtKB/TrEMBL
  M0RAC8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Macrod2  mono-ADP ribosylhydrolase 2  AABR07054000.1    Data merged from RGD:15006039 737654 PROVISIONAL
2021-03-09 Macrod2  mono-ADP ribosylhydrolase 2  LOC102548740  uncharacterized LOC102548740  Data merged from RGD:7507054 737654 PROVISIONAL
2019-11-08 AABR07054000.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2019-04-10 Macrod2  mono-ADP ribosylhydrolase 2  Macrod2  MACRO domain containing 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102548740  uncharacterized LOC102548740      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-05-24 Macrod2  MACRO domain containing 2  LOC688083  similar to LRP16 protein  Data merged from RGD:1593580 1643240 APPROVED
2012-01-18 Macrod2  MACRO domain containing 2  LOC685695  similar to SON protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC685695  similar to SON protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC688083  similar to LRP16 protein      Symbol and Name status set to provisional 70820 PROVISIONAL