Tpt1l2 (tumor protein, translationally-controlled 1 like 2) - Rat Genome Database

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Gene: Tpt1l2 (tumor protein, translationally-controlled 1 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Tpt1l2 (Ensembl: LOC685718)
Name: tumor protein, translationally-controlled 1 like 2 (Ensembl:similar to tumor protein, translationally-controlled 1)
RGD ID: 1590250
Description: Predicted to enable DNA-binding transcription factor binding activity. Predicted to be involved in negative regulation of ectoderm development and stem cell population maintenance. Predicted to be located in nucleoplasm.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC685718; similar to tumor protein, translationally-controlled 1; Tpt1l1; translationally-controlled tumor protein-like; tumor protein, translationally-controlled 1 like 1
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21612,476,660 - 12,477,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1612,476,735 - 12,477,253 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01613,950,401 - 13,950,949 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01613,841,678 - 13,842,196 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41612,907,137 - 12,912,718 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1612,734,189 - 12,734,737 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Tpt1l2
5 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)16285170915884239Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760916039848Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16422773017696785Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000048912   ⟹   ENSRNOP00000094066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1612,476,735 - 12,477,253 (+)Ensembl
Rnor_6.0 Ensembl1613,950,416 - 13,950,934 (+)Ensembl
RefSeq Acc Id: XM_039094897   ⟹   XP_038950825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21612,476,660 - 12,477,351 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038950825 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000082883.1
  ENSRNOP00000094066
  ENSRNOP00000094066.1
Reference Protein Sequences
RefSeq Acc Id: XP_038950825   ⟸   XM_039094897
- UniProtKB: A0A8I6AN27 (UniProtKB/TrEMBL),   A0A8I5ZVT0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000094066   ⟸   ENSRNOT00000048912
Protein Domains
TCTP

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-12003 BioCyc
Ensembl Genes ENSRNOG00000001049 UniProtKB/TrEMBL
  ENSRNOG00000030299 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048912 ENTREZGENE
  ENSRNOT00000048912.6 UniProtKB/TrEMBL
  ENSRNOT00000106386.1 UniProtKB/TrEMBL
InterPro Mss4-like_sf UniProtKB/TrEMBL
  Mss4/transl-control_tumour UniProtKB/TrEMBL
  TCTP UniProtKB/TrEMBL
  Translation_control_tumour_CS UniProtKB/TrEMBL
  Translational_control_tumour_p UniProtKB/TrEMBL
NCBI Gene 685718 ENTREZGENE
PANTHER PTHR11991 UniProtKB/TrEMBL
  TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN UniProtKB/TrEMBL
Pfam TCTP UniProtKB/TrEMBL
PhenoGen Tpt1l2 PhenoGen
PRINTS TCTPROTEIN UniProtKB/TrEMBL
PROSITE TCTP_1 UniProtKB/TrEMBL
  TCTP_2 UniProtKB/TrEMBL
  TCTP_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001049 RatGTEx
  ENSRNOG00000030299 RatGTEx
Superfamily-SCOP SSF51316 UniProtKB/TrEMBL
UniProt A0A8I5ZVT0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AN27 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-17 Tpt1l2  tumor protein, translationally-controlled 1 like 2  Tpt1l1  tumor protein, translationally-controlled 1 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Tpt1l1  tumor protein, translationally-controlled 1 like 1  LOC685718  similar to tumor protein, translationally-controlled 1  Symbol and Name Changed 1299863 APPROVED
2006-11-20 LOC685718  similar to tumor protein, translationally-controlled 1      Symbol and Name status set to provisional 70820 PROVISIONAL