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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tprg1l | Rat | (-)-demecolcine | increases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Demecolcine results in increased expression of TPRG1L mRNA | CTD | PMID:23649840 | Tprg1l | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tprg1l (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of TPRG1L mRNA] | CTD | PMID:22206623 | Tprg1l | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Tprg1l (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TPRG1L mRNA | CTD | PMID:22206623 | Tprg1l | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Tprg1l (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of TPRG1L mRNA | CTD | PMID:17555576 | Tprg1l | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Tprg1l (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Tprg1l | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tprg1l (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TPRG1L mRNA | CTD | PMID:21570461 | Tprg1l | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TPRG1L mRNA | CTD | PMID:33387578 | Tprg1l | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TPRG1L mRNA | CTD | PMID:34747641 | Tprg1l | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of TPRG1L protein | CTD | PMID:34915118 | Tprg1l | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TPRG1L mRNA | CTD | PMID:30047161 | Tprg1l | Rat | acrylamide | increases expression | ISO | Tprg1l (Mus musculus) | 6480464 | Acrylamide results in increased expression of TPRG1L mRNA | CTD | PMID:30807115 | Tprg1l | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of TPRG1L mRNA | CTD | PMID:30047161 | Tprg1l | Rat | aristolochic acid A | increases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TPRG1L mRNA | CTD | PMID:33212167 | Tprg1l | Rat | atrazine | decreases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Atrazine results in decreased expression of TPRG1L mRNA | CTD | PMID:22378314 | Tprg1l | Rat | benzo[a]pyrene | increases methylation | ISO | TPRG1L (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TPRG1L promoter | CTD | PMID:27901495 | Tprg1l | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TPRG1L mRNA | CTD | PMID:25181051 | Tprg1l | Rat | bisphenol A | increases expression | ISO | Tprg1l (Mus musculus) | 6480464 | bisphenol A results in increased expression of TPRG1L mRNA | CTD | PMID:33221593 | Tprg1l | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TPRG1L mRNA | CTD | PMID:30816183 more ... | Tprg1l | Rat | cadmium dichloride | decreases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TPRG1L mRNA | CTD | PMID:38568856 | Tprg1l | Rat | carbon nanotube | decreases expression | ISO | Tprg1l (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Tprg1l | Rat | choline | multiple interactions | ISO | Tprg1l (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of TPRG1L gene | CTD | PMID:20938992 | Tprg1l | Rat | corosolic acid | increases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | corosolic acid results in increased expression of TPRG1L mRNA | CTD | PMID:37939859 | Tprg1l | Rat | coumestrol | multiple interactions | ISO | TPRG1L (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in decreased expression of TPRG1L mRNA | CTD | PMID:19167446 | Tprg1l | Rat | diazinon | increases methylation | ISO | TPRG1L (Homo sapiens) | 6480464 | Diazinon results in increased methylation of TPRG1L gene | CTD | PMID:22964155 | Tprg1l | Rat | Dibutyl phosphate | affects expression | ISO | TPRG1L (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TPRG1L mRNA | CTD | PMID:37042841 | Tprg1l | Rat | diethylstilbestrol | decreases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of TPRG1L mRNA | CTD | PMID:36621641 | Tprg1l | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of TPRG1L mRNA | CTD | PMID:24136188 | Tprg1l | Rat | folic acid | multiple interactions | ISO | Tprg1l (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of TPRG1L gene more ... | CTD | PMID:20938992 and PMID:22206623 | Tprg1l | Rat | formaldehyde | increases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of TPRG1L mRNA | CTD | PMID:23649840 | Tprg1l | Rat | isoflurane | increases expression | ISO | Tprg1l (Mus musculus) | 6480464 | Isoflurane results in increased expression of TPRG1L protein | CTD | PMID:35249202 | Tprg1l | Rat | ivermectin | decreases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TPRG1L protein | CTD | PMID:32959892 | Tprg1l | Rat | L-methionine | multiple interactions | ISO | Tprg1l (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of TPRG1L gene | CTD | PMID:20938992 | Tprg1l | Rat | lead(0) | affects expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Lead affects the expression of TPRG1L mRNA | CTD | PMID:28903495 | Tprg1l | Rat | leflunomide | decreases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | leflunomide results in decreased expression of TPRG1L mRNA | CTD | PMID:28988120 | Tprg1l | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of TPRG1L mRNA | CTD | PMID:30047161 | Tprg1l | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of TPRG1L mRNA | CTD | PMID:24136188 | Tprg1l | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of TPRG1L mRNA | CTD | PMID:24136188 | Tprg1l | Rat | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of TPRG1L mRNA | CTD | PMID:30047161 | Tprg1l | Rat | resveratrol | multiple interactions | ISO | TPRG1L (Homo sapiens) | 6480464 | [Coumestrol co-treated with Resveratrol] results in decreased expression of TPRG1L mRNA and [Plant Extracts co-treated with Resveratrol] results in increased expression of TPRG1L mRNA | CTD | PMID:19167446 and PMID:23557933 | Tprg1l | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of TPRG1L mRNA | CTD | PMID:28374803 | Tprg1l | Rat | silicon dioxide | increases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of TPRG1L mRNA | CTD | PMID:25895662 | Tprg1l | Rat | sodium arsenite | increases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TPRG1L mRNA | CTD | PMID:38568856 | Tprg1l | Rat | sodium fluoride | decreases expression | ISO | Tprg1l (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of TPRG1L protein | CTD | PMID:28918527 | Tprg1l | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of TPRG1L mRNA | CTD | PMID:30047161 | Tprg1l | Rat | tamoxifen | affects expression | ISO | Tprg1l (Mus musculus) | 6480464 | Tamoxifen affects the expression of TPRG1L mRNA | CTD | PMID:17555576 | Tprg1l | Rat | titanium dioxide | decreases methylation | ISO | Tprg1l (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TPRGL promoter alternative form | CTD | PMID:35295148 | Tprg1l | Rat | triphenyl phosphate | affects expression | ISO | TPRG1L (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TPRG1L mRNA | CTD | PMID:37042841 | Tprg1l | Rat | tunicamycin | decreases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of TPRG1L mRNA | CTD | PMID:29453283 | Tprg1l | Rat | valproic acid | increases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TPRG1L mRNA | CTD | PMID:23179753 and PMID:28001369 | Tprg1l | Rat | valproic acid | increases methylation | ISO | TPRG1L (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TPRG1L gene | CTD | PMID:29154799 | Tprg1l | Rat | vincristine | increases expression | ISO | TPRG1L (Homo sapiens) | 6480464 | Vincristine results in increased expression of TPRG1L mRNA | CTD | PMID:23649840 | |