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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rnf14 | Rat | (+)-catechin | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of RNF14 mRNA | CTD | PMID:24763279 | Rnf14 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RNF14 mRNA] | CTD | PMID:31150632 | Rnf14 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Rnf14 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RNF14 mRNA | CTD | PMID:22206623 | Rnf14 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Rnf14 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of RNF14 mRNA | CTD | PMID:22206623 | Rnf14 | Rat | 17beta-estradiol | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Estradiol affects the expression of RNF14 mRNA | CTD | PMID:14699072 | Rnf14 | Rat | 17beta-estradiol | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of RNF14 mRNA | CTD | PMID:20404318 | Rnf14 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rnf14 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RNF14 mRNA | CTD | PMID:20702594|PMID:21570461 | Rnf14 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | affects expression | ISO | Rnf14 (Mus musculus) | 6480464 | 2,3,7,8-tetrachlorodibenzofuran affects the expression of RNF14 mRNA | CTD | PMID:20702594 | Rnf14 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of RNF14 mRNA | CTD | PMID:21346803 | Rnf14 | Rat | 2-methylcholine | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of RNF14 mRNA | CTD | PMID:21179406 | Rnf14 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of RNF14 protein | CTD | PMID:34915118 | Rnf14 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Rnf14 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of RNF14 mRNA | CTD | PMID:39298647 | Rnf14 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of RNF14 protein | CTD | PMID:34186270 | Rnf14 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Decitabine affects the expression of RNF14 mRNA | CTD | PMID:23300844 | Rnf14 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of RNF14 mRNA | CTD | PMID:30047161 | Rnf14 | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of RNF14 mRNA | CTD | PMID:28959563 | Rnf14 | Rat | aflatoxin B1 | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of RNF14 mRNA | CTD | PMID:19770486 | Rnf14 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of RNF14 mRNA | CTD | PMID:30047161 | Rnf14 | Rat | aristolochic acid A | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of RNF14 mRNA; aristolochic acid I results in more ... | CTD | PMID:33212167 | Rnf14 | Rat | Aroclor 1254 | decreases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of RNF14 mRNA | CTD | PMID:23650126 | Rnf14 | Rat | arsane | decreases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Arsenic results in decreased expression of RNF14 mRNA | CTD | PMID:19654921 | Rnf14 | Rat | arsenic atom | decreases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Arsenic results in decreased expression of RNF14 mRNA | CTD | PMID:19654921 | Rnf14 | Rat | arsenite(3-) | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to RNF14 mRNA] | CTD | PMID:32406909 | Rnf14 | Rat | benzo[a]pyrene | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RNF14 mRNA | CTD | PMID:22228805 | Rnf14 | Rat | benzo[a]pyrene | decreases methylation | ISO | RNF14 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of RNF14 promoter | CTD | PMID:27901495 | Rnf14 | Rat | benzo[a]pyrene | affects methylation | ISO | RNF14 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RNF14 5' UTR | CTD | PMID:27901495 | Rnf14 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of RNF14 mRNA | CTD | PMID:21318169 | Rnf14 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RNF14 mRNA | CTD | PMID:25181051 | Rnf14 | Rat | bisphenol A | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of RNF14 protein | CTD | PMID:34186270 | Rnf14 | Rat | bisphenol A | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | bisphenol A results in increased expression of RNF14 mRNA | CTD | PMID:33221593 | Rnf14 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RNF14 mRNA | CTD | PMID:30816183|PMID:34947998 | Rnf14 | Rat | bisphenol F | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | bisphenol F results in increased expression of RNF14 mRNA | CTD | PMID:38685157 | Rnf14 | Rat | bortezomib | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of RNF14 mRNA | CTD | PMID:20977926 | Rnf14 | Rat | cadmium dichloride | decreases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of RNF14 protein | CTD | PMID:38185225 | Rnf14 | Rat | CGP 52608 | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to RNF14 gene] | CTD | PMID:28238834 | Rnf14 | Rat | chlorpyrifos | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of RNF14 mRNA | CTD | PMID:37019170 | Rnf14 | Rat | chromium(6+) | decreases expression | EXP | | 6480464 | chromium hexavalent ion results in decreased expression of RNF14 protein | CTD | PMID:32679048 | Rnf14 | Rat | cisplatin | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Cisplatin affects the expression of RNF14 mRNA | CTD | PMID:23300844 | Rnf14 | Rat | cobalt dichloride | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of RNF14 mRNA | CTD | PMID:19376846 | Rnf14 | Rat | cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of RNF14 protein | CTD | PMID:25100957 | Rnf14 | Rat | crocidolite asbestos | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Asbestos, Crocidolite affects the expression of RNF14 mRNA | CTD | PMID:17331233 | Rnf14 | Rat | cyclosporin A | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of RNF14 mRNA | CTD | PMID:25562108 | Rnf14 | Rat | cylindrospermopsin | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of RNF14 mRNA | CTD | PMID:24921660 | Rnf14 | Rat | Dibutyl phosphate | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of RNF14 mRNA | CTD | PMID:37042841 | Rnf14 | Rat | dicyclanil | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | dicyclanil results in increased expression of RNF14 mRNA | CTD | PMID:15664270 | Rnf14 | Rat | diethyl maleate | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | diethyl maleate results in increased expression of RNF14 mRNA | CTD | PMID:25270620 | Rnf14 | Rat | dioxygen | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of RNF14 mRNA | CTD | PMID:22629407 | Rnf14 | Rat | dioxygen | multiple interactions | ISO | Rnf14 (Mus musculus) | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of RNF14 mRNA] | CTD | PMID:22629407 | Rnf14 | Rat | enzyme inhibitor | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Rnf14 | Rat | ethanol | affects splicing | ISO | Rnf14 (Mus musculus) | 6480464 | Ethanol affects the splicing of RNF14 mRNA | CTD | PMID:30319688 | Rnf14 | Rat | ethyl methanesulfonate | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of RNF14 mRNA | CTD | PMID:23649840 | Rnf14 | Rat | fenofibrate | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Fenofibrate results in increased expression of RNF14 mRNA | CTD | PMID:21318169 | Rnf14 | Rat | fenofibrate | multiple interactions | ISO | Rnf14 (Mus musculus) | 6480464 | PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA] | CTD | PMID:21318169 | Rnf14 | Rat | folic acid | multiple interactions | ISO | Rnf14 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RNF14 mRNA | CTD | PMID:22206623 | Rnf14 | Rat | FR900359 | increases phosphorylation | ISO | RNF14 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of RNF14 protein | CTD | PMID:37730182 | Rnf14 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of RNF14 mRNA | CTD | PMID:30047161 | Rnf14 | Rat | methyl methanesulfonate | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of RNF14 mRNA | CTD | PMID:23649840 | Rnf14 | Rat | methylmercury chloride | decreases expression | ISO | RNF14 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of RNF14 mRNA | CTD | PMID:28001369 | Rnf14 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of RNF14 mRNA | CTD | PMID:24136188 | Rnf14 | Rat | paracetamol | affects expression | ISO | Rnf14 (Mus musculus) | 6480464 | Acetaminophen affects the expression of RNF14 mRNA | CTD | PMID:17562736 | Rnf14 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of RNF14 mRNA | CTD | PMID:33387578 | Rnf14 | Rat | paracetamol | decreases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of RNF14 mRNA | CTD | PMID:21420995 | Rnf14 | Rat | phenobarbital | affects expression | ISO | Rnf14 (Mus musculus) | 6480464 | Phenobarbital affects the expression of RNF14 mRNA | CTD | PMID:23091169 | Rnf14 | Rat | quercetin | decreases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of RNF14 mRNA | CTD | PMID:21632981 | Rnf14 | Rat | quercitrin | decreases expression | ISO | RNF14 (Homo sapiens) | 6480464 | quercitrin results in decreased expression of RNF14 mRNA | CTD | PMID:25193878 | Rnf14 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of RNF14 mRNA | CTD | PMID:30047161 | Rnf14 | Rat | testosterone | decreases expression | ISO | Rnf14 (Mus musculus) | 6480464 | Testosterone results in decreased expression of RNF14 mRNA | CTD | PMID:21669218 | Rnf14 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RNF14 mRNA] | CTD | PMID:31150632 | Rnf14 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of RNF14 mRNA | CTD | PMID:31150632 | Rnf14 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of RNF14 mRNA | CTD | PMID:34492290 | Rnf14 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of RNF14 mRNA | CTD | PMID:33387578 | Rnf14 | Rat | trichostatin A | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | trichostatin A affects the expression of RNF14 mRNA | CTD | PMID:28542535 | Rnf14 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of RNF14 mRNA | CTD | PMID:30589522 | Rnf14 | Rat | triphenyl phosphate | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of RNF14 mRNA | CTD | PMID:37042841 | Rnf14 | Rat | triptonide | increases expression | ISO | Rnf14 (Mus musculus) | 6480464 | triptonide results in increased expression of RNF14 mRNA | CTD | PMID:33045310 | Rnf14 | Rat | urethane | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Urethane results in increased expression of RNF14 mRNA | CTD | PMID:28818685 | Rnf14 | Rat | valproic acid | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RNF14 mRNA | CTD | PMID:25979313 | Rnf14 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of RNF14 gene | CTD | PMID:31682807 | |