Awat1 (acyl-CoA wax alcohol acyltransferase 1)

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Gene: Awat1 (acyl-CoA wax alcohol acyltransferase 1) Rattus norvegicus

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Symbol:

Awat1

Name:

acyl-CoA wax alcohol acyltransferase 1

RGD ID:

1587163

Description:

Predicted to enable long-chain-alcohol O-fatty-acyltransferase activity. Predicted to be involved in lipid metabolic process. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human AWAT1 (acyl-CoA wax alcohol acyltransferase 1); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; INTERACTS WITH bisphenol A; copper atom; copper(0).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Dgat2l3; diacylglycerol O-acyltransferase 2-like 3; LOC679520; similar to diacylglycerol O-acyltransferase 2-like 3; wax synthase 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AWAT1 (acyl-CoA wax alcohol acyltransferase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Awat1 (acyl-CoA wax alcohol acyltransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Awat1 (acyl-CoA wax alcohol acyltransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AWAT1 (acyl-CoA wax alcohol acyltransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AWAT1 (acyl-CoA wax alcohol acyltransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Awat1 (acyl-CoA wax alcohol acyltransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AWAT1 (acyl-CoA wax alcohol acyltransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AWAT1 (acyl-CoA wax alcohol acyltransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Awat1 (acyl-CoA wax alcohol acyltransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GOPC (golgi associated PDZ and coiled-coil motif containing)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	AWAT1 (acyl-CoA wax alcohol acyltransferase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Awat1 (acyl-CoA wax alcohol acyltransferase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG1941	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DGA1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	K07B1.4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	Y53G8B.2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	dgat-2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	dgtr-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG1946	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Dgat2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	69,708,286 - 69,714,531 (+)	NCBI		GRCr8
mRatBN7.2	X	65,668,205 - 65,674,450 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	65,668,205 - 65,674,450 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	67,151,614 - 67,157,859 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	70,652,006 - 70,658,251 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	68,212,905 - 68,219,150 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	70,408,124 - 70,414,369 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	70,408,064 - 70,414,368 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	71,279,694 - 71,285,939 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	88,570,707 - 88,576,952 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	66,027,072 - 66,033,317 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

clothianidin (ISO)

copper atom (EXP)

copper(0) (EXP)

furan (EXP)

nickel atom (ISO)

ozone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular lipid metabolic process (IEA)

lipid metabolic process (IBA)

Cellular Component

endoplasmic reticulum membrane (IBA)

Molecular Function

long-chain-alcohol O-fatty-acyltransferase activity (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

retinol metabolic pathway (ISO)

vitamin A deficiency pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15671038

Genomics

Comparative Map Data

Awat1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	69,708,286 - 69,714,531 (+)	NCBI		GRCr8
mRatBN7.2	X	65,668,205 - 65,674,450 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	65,668,205 - 65,674,450 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	67,151,614 - 67,157,859 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	70,652,006 - 70,658,251 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	68,212,905 - 68,219,150 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	70,408,124 - 70,414,369 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	70,408,064 - 70,414,368 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	71,279,694 - 71,285,939 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	88,570,707 - 88,576,952 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	66,027,072 - 66,033,317 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

AWAT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	70,234,655 - 70,240,659 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	70,234,655 - 70,240,659 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	69,454,505 - 69,460,509 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	69,371,271 - 69,376,865 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	X	69,807,845 - 69,813,851 (+)	NCBI		Celera
Cytogenetic Map	X	q13.1	NCBI
HuRef	X	63,275,596 - 63,281,709 (+)	NCBI		HuRef
CHM1_1	X	69,348,486 - 69,354,491 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	68,667,982 - 68,673,985 (+)	NCBI		T2T-CHM13v2.0

Awat1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	99,615,853 - 99,621,812 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	99,615,857 - 99,621,811 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	100,572,247 - 100,578,206 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	100,572,251 - 100,578,205 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	97,767,586 - 97,773,545 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	96,774,966 - 96,780,925 (+)	NCBI		MGSCv36	mm8
Celera	X	87,498,297 - 87,504,256 (+)	NCBI		Celera
Cytogenetic Map	X	C3	NCBI
cM Map	X	43.72	NCBI

Awat1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955475	9,780,080 - 9,789,448 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955475	9,780,080 - 9,785,675 (+)	NCBI	ChiLan1.0	ChiLan1.0

AWAT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	69,911,653 - 69,917,948 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	69,915,381 - 69,921,550 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	59,502,965 - 59,509,092 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	69,562,111 - 69,568,244 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	69,562,111 - 69,568,244 (+)	Ensembl	panpan1.1		panPan2

AWAT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	54,678,459 - 54,684,666 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	54,622,317 - 54,684,231 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	45,504,680 - 45,511,082 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	55,645,037 - 55,651,439 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	55,588,452 - 55,651,935 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	53,614,019 - 53,620,420 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	54,944,818 - 54,951,220 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	54,871,995 - 54,878,397 (+)	NCBI		UU_Cfam_GSD_1.0

Awat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	47,475,829 - 47,482,162 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936762	1,238,473 - 1,244,330 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936762	1,238,239 - 1,244,330 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AWAT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	X	56,263,082 - 56,273,169 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	63,457,862 - 63,467,957 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AWAT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	60,076,303 - 60,082,917 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	60,076,817 - 60,082,546 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	1,922,962 - 1,929,092 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Awat1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624903	198,012 - 204,067 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624903	198,012 - 204,697 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Awat1
16 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	48
Count of miRNA genes:	45
Interacting mature miRNAs:	48
Transcripts:	ENSRNOT00000038924
Prediction methods:	Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	65612192	120568734	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	41304447	112935181	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	respiratory system
8	2	2	1	1	1	6	2	1	2	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141377	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000038924 ⟹ ENSRNOP00000032529

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	65,668,205 - 65,674,450 (+)	Ensembl
Rnor_6.0 Ensembl	X	70,408,064 - 70,414,368 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076053

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	X	70,408,074 - 70,410,722 (+)	Ensembl

RefSeq Acc Id:

NM_001109371 ⟹ NP_001102841

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	69,708,286 - 69,714,531 (+)	NCBI
mRatBN7.2	X	65,668,205 - 65,674,450 (+)	NCBI
Rnor_6.0	X	70,408,124 - 70,414,369 (+)	NCBI
Rnor_5.0	X	71,279,694 - 71,285,939 (+)	NCBI
RGSC_v3.4	X	88,570,707 - 88,576,952 (+)	RGD
Celera	X	66,027,072 - 66,033,317 (+)	RGD

Sequence:

show sequence

TTACCTCCCTCAGGGCCCTGGGCATCATGTCTTGCTCTATGAAGCTTGAATACTTACAAAGTCT
GAGTCTTCTGCAGTGGCCCTTGAGCTACCTTGCTATCTTTTGGATCGTGCAGCCATTGTTCTTT
AGCCTATTTTTCACACCCTTGTGGCTGCTACCATCACTTTACGTTGTGTGGTTCATTCTGGACT
GGAAGACTCCAAATCAAGGTGGCAGGCGTTCAGCCTGGGTAAGGAACTGGAACATCTGGACCCA
CATCAGGGATTATTTCCCCATTACAATCCTGAAGACTAAGGACCTGTCACCTTCACAGAACTAC
ATCATGGGGGTCCACCCCCATGGTCTCCTGACCTTCGGTGCCTTCTGCAACTTCTGTACTGAGG
CCACAGGCTTCTCGAAGACCTTCCCAGGCATCACTCCTCACTTGGCCACACTGTCCTGGTTCTT
CAAGATCCCCCTTATTAGGGACTACATCATGGCCAAAGGAGTGTGTTCTGTGAGCCAAGCATCC
ATCGACTACCTGCTGAGCCATGGCACTGGAAACCTCGTGGGCATTGTTGTGGGAGGAGTGGGAG
AGGCCCTACAGAGTGTGCCGAACACCACCACCCTCATCCTCAAGAAGCGCAAAGGGTTTGTGCG
CACAGCCCTCCGACATGGGGCTCATCTGGTCCCTACCTTCACATTTGGAGAAACAGAGGTATAT
GACCAGGTAGTGTTCCATGAGGAGAGCCGGATGTTCAAGTTCCAAAGCTTCTTTCGCCGGATCT
TCGGGTTCTATTTTTGTGTCTTCTATGGACAAGGCTTCCATCAAGAATGTAAGGGACTCCTACC
ATACCACAGACCCATCGTCACTGTAGTTGGGGAACCTTTGCCACTACCCCAGGTTAAAAACCCA
AGCCCAGAGATAGTGGACAAATACCATGCACTCTACATGGATGCCCTGTACAAGCTGTTTGAGC
AACACAAGGTCCAGTATGGCTGCTCCGACACCCAGAAGCTGATGTTCTTGTGATCAAAGCAACT
GTGTGCATCCTAGAGCATGGCAGAACCTGTGGAAACTGTGTTGCCTAGAACTGGAGTCCTGGGA
AAGGGGGAAAGTAAGGAAGATGAAGGAGGTTATGTGTGCAGTCAGGGAGGGGACATTAAGAGCT
CCTTTGTGACCATAATGCTGCCCCTGCCTGCACCCTCACAGGAGTTGTCCCTGAGGATCTCCAC
CCAGACATTCTTCAGAGGGGACATCCTGAGGCCCCTCTTAGCCCATGCACTTTCTGAACCTGAA
ATTCTTGAATCCAATCCAATTTTTAAAAAAATTTTAATAAAAGATTAAATT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102841	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL95936	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032529.3

RefSeq Acc Id:

NP_001102841 ⟸ NM_001109371

- UniProtKB:

D3ZVA9 (UniProtKB/TrEMBL), A6IQ77 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSCSMKLEYLQSLSLLQWPLSYLAIFWIVQPLFFSLFFTPLWLLPSLYVVWFILDWKTPNQGGR
RSAWVRNWNIWTHIRDYFPITILKTKDLSPSQNYIMGVHPHGLLTFGAFCNFCTEATGFSKTFP
GITPHLATLSWFFKIPLIRDYIMAKGVCSVSQASIDYLLSHGTGNLVGIVVGGVGEALQSVPNT
TTLILKKRKGFVRTALRHGAHLVPTFTFGETEVYDQVVFHEESRMFKFQSFFRRIFGFYFCVFY
GQGFHQECKGLLPYHRPIVTVVGEPLPLPQVKNPSPEIVDKYHALYMDALYKLFEQHKVQYGCS
DTQKLMFL

hide sequence

Ensembl Acc Id:

ENSRNOP00000032529 ⟸ ENSRNOT00000038924

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZVA9-F1-model_v2	AlphaFold	D3ZVA9	1-328	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1587163	AgrOrtholog
BioCyc Gene	G2FUF-2131	BioCyc
Ensembl Genes	ENSRNOG00000026231	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038924.5	UniProtKB/TrEMBL
InterPro	DAGAT	UniProtKB/TrEMBL
KEGG Report	rno:679520	UniProtKB/TrEMBL
NCBI Gene	679520	ENTREZGENE
PANTHER	ACYL-COA WAX ALCOHOL ACYLTRANSFERASE 1	UniProtKB/TrEMBL
	DIACYLGLYCEROL O-ACYLTRANSFERASE	UniProtKB/TrEMBL
Pfam	DAGAT	UniProtKB/TrEMBL
PhenoGen	Awat1	PhenoGen
RatGTEx	ENSRNOG00000026231	RatGTEx
UniProt	A6IQ77	ENTREZGENE, UniProtKB/TrEMBL
	D3ZVA9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-03-24	Awat1	acyl-CoA wax alcohol acyltransferase 1	Dgat2l3	diacylglycerol O-acyltransferase 2-like 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Dgat2l3	diacylglycerol O-acyltransferase 2-like 3	LOC679520	similar to diacylglycerol O-acyltransferase 2-like 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC679520	similar to diacylglycerol O-acyltransferase 2-like 3	LOC684251	similar to diacylglycerol O-acyltransferase 2-like 3	Data merged from RGD:1592696	1643240	APPROVED
2006-11-20	LOC684251	similar to diacylglycerol O-acyltransferase 2-like 3			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC679520	similar to diacylglycerol O-acyltransferase 2-like 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB