Tomm20l (translocase of outer mitochondrial membrane 20 like) - Rat Genome Database

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Gene: Tomm20l (translocase of outer mitochondrial membrane 20 like) Rattus norvegicus
Analyze
Symbol: Tomm20l
Name: translocase of outer mitochondrial membrane 20 like
RGD ID: 1586305
Description: Predicted to be involved in intracellular protein transport. Orthologous to human TOMM20L (translocase of outer mitochondrial membrane 20 like); INTERACTS WITH bisphenol A; 2,3',4,4',5-Pentachlorobiphenyl (ortholog); aldehydo-D-glucose (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AC128303.1; LOC689996; similar to translocase of outer mitochondrial membrane 20 homolog; TOMM20-like protein 1; Tomm20l1; translocase of outer mitochondrial membrane 20 homolog (yeast)-like; translocase of outer mitochondrial membrane 20 homolog-like; translocase of outer mitochondrial membrane 20 like 1
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8695,335,681 - 95,346,116 (+)NCBIGRCr8
mRatBN7.2689,594,016 - 89,612,070 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl689,599,873 - 89,610,147 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0693,538,377 - 93,549,533 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,539,271 - 93,651,154 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.06103,004,605 - 103,015,121 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4693,208,302 - 93,218,521 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera688,083,111 - 88,094,268 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Tomm20l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8695,335,681 - 95,346,116 (+)NCBIGRCr8
mRatBN7.2689,594,016 - 89,612,070 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl689,599,873 - 89,610,147 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0693,538,377 - 93,549,533 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,539,271 - 93,651,154 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.06103,004,605 - 103,015,121 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4693,208,302 - 93,218,521 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera688,083,111 - 88,094,268 (+)NCBICelera
Cytogenetic Map6q24NCBI
TOMM20L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381458,395,930 - 58,417,080 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1458,395,928 - 58,408,702 (+)EnsemblGRCh38hg38GRCh38
GRCh371458,862,648 - 58,875,420 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361457,932,385 - 57,945,172 (+)NCBINCBI36Build 36hg18NCBI36
Celera1438,912,616 - 38,925,391 (+)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1439,027,270 - 39,040,037 (+)NCBIHuRef
CHM1_11458,801,207 - 58,813,988 (+)NCBICHM1_1
T2T-CHM13v2.01452,602,950 - 52,624,123 (+)NCBIT2T-CHM13v2.0
Tomm20l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391271,158,202 - 71,169,996 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1271,158,202 - 71,169,995 (+)EnsemblGRCm39 Ensembl
GRCm381271,111,428 - 71,123,222 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1271,111,428 - 71,123,221 (+)EnsemblGRCm38mm10GRCm38
MGSCv371272,212,415 - 72,224,209 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1272,211,475 - 72,223,254 (+)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1229.39NCBI
TOMM20L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21559,517,614 - 59,531,404 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11458,728,289 - 58,748,838 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01438,987,239 - 39,001,441 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11457,255,851 - 57,268,343 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1457,255,851 - 57,268,343 (+)Ensemblpanpan1.1panPan2
TOMM20L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1833,747,643 - 33,761,655 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl833,747,284 - 33,755,880 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha833,508,932 - 33,517,299 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0833,989,091 - 33,997,455 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl833,989,091 - 33,997,435 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1833,601,633 - 33,609,978 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0833,669,762 - 33,678,101 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0834,044,093 - 34,052,460 (+)NCBIUU_Cfam_GSD_1.0
Tomm20l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864071,392,612 - 71,412,432 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364952,779,851 - 2,786,233 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOMM20L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1187,475,006 - 187,486,729 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11187,474,745 - 187,496,040 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21208,367,169 - 208,408,948 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TOMM20L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12435,578,996 - 35,591,613 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2435,579,540 - 35,591,495 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605323,859,161 - 23,881,058 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Tomm20l
134 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat

Markers in Region
RH141247  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,610,241 - 89,610,424 (+)MAPPERmRatBN7.2
Rnor_6.0693,549,632 - 93,549,814NCBIRnor6.0
Rnor_5.06103,015,220 - 103,015,402UniSTSRnor5.0
RGSC_v3.4693,218,665 - 93,218,847UniSTSRGSC3.4
Celera688,094,367 - 88,094,549UniSTS
RH 3.4 Map6639.2UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000078791   ⟹   ENSRNOP00000068942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl689,599,873 - 89,610,147 (+)Ensembl
RefSeq Acc Id: XM_001072851   ⟹   XP_001072851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,335,681 - 95,346,116 (+)NCBI
mRatBN7.2689,594,016 - 89,612,070 (+)NCBI
Rnor_6.0693,538,383 - 93,549,533 (+)NCBI
Rnor_5.06103,004,605 - 103,015,121 (+)NCBI
RGSC_v3.4693,208,302 - 93,218,521 (+)RGD
Sequence:
RefSeq Acc Id: XM_039113236   ⟹   XP_038969164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,335,681 - 95,337,512 (+)NCBI
mRatBN7.2689,594,016 - 89,601,536 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001419105 (Get FASTA)   NCBI Sequence Viewer  
  XP_001072851 (Get FASTA)   NCBI Sequence Viewer  
  XP_038969164 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03567 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000068942.2
RefSeq Acc Id: XP_001072851   ⟸   XM_001072851
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_038969164   ⟸   XM_039113236
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000068942   ⟸   ENSRNOT00000078791

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JU30-F1-model_v2 AlphaFold A0A0G2JU30 1-143 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694655
Promoter ID:EPDNEW_R5172
Type:initiation region
Name:AC128303_1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0693,539,251 - 93,539,311EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586305 AgrOrtholog
BioCyc Gene G2FUF-37184 BioCyc
Ensembl Genes ENSRNOG00000054663 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078791.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.960.10 UniProtKB/TrEMBL
InterPro MAS20 UniProtKB/TrEMBL
  MAS20_rcpt_metazoan UniProtKB/TrEMBL
  Tom20_dom_sf UniProtKB/TrEMBL
NCBI Gene 689996 ENTREZGENE
PANTHER PTHR12430 UniProtKB/TrEMBL
  TOMM20-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam MAS20 UniProtKB/TrEMBL
PhenoGen Tomm20l PhenoGen
PIRSF MAS20_rcpt UniProtKB/TrEMBL
PRINTS EUOM20RECPTR UniProtKB/TrEMBL
  OM20RECEPTOR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000054663 RatGTEx
Superfamily-SCOP SSF47157 UniProtKB/TrEMBL
UniProt A0A0G2JU30 ENTREZGENE, UniProtKB/TrEMBL
  A6HC12 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Tomm20l  translocase of outer mitochondrial membrane 20 like  AC128303.1    Data merged from RGD:15008855 737654 PROVISIONAL
2019-11-08 AC128303.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2016-03-01 Tomm20l  translocase of outer mitochondrial membrane 20 like  Tomm20l  translocase of outer mitochondrial membrane 20 homolog (yeast)-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-05-31 Tomm20l  translocase of outer mitochondrial membrane 20 homolog (yeast)-like   LOC689996  similar to translocase of outer mitochondrial membrane 20 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC689996  similar to translocase of outer mitochondrial membrane 20 homolog  LOC687901  similar to translocase of outer mitochondrial membrane 20 homolog  Data merged from RGD:1594947 1643240 APPROVED
2006-11-20 LOC687901  similar to translocase of outer mitochondrial membrane 20 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC689996  similar to translocase of outer mitochondrial membrane 20 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL