Rnf207 (ring finger protein 207) - Rat Genome Database

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Pathways
Gene: Rnf207 (ring finger protein 207) Rattus norvegicus
Analyze
Symbol: Rnf207
Name: ring finger protein 207
RGD ID: 1586262
Description: Predicted to enable Hsp70 protein binding activity and transmembrane transporter binding activity. Predicted to be involved in positive regulation of gene expression; regulation of cardiac muscle contraction; and regulation of heart looping. Predicted to be located in cytoplasm. Predicted to be active in perinuclear region of cytoplasm. Orthologous to human RNF207 (ring finger protein 207); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC691246; similar to tripartite motif-containing 56
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85168,098,074 - 168,112,585 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5168,097,456 - 168,111,094 (-)EnsemblGRCr8
mRatBN7.25162,815,351 - 162,828,325 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,815,357 - 162,828,375 (-)EnsemblmRatBN7.2
Rnor_6.05169,486,253 - 169,500,451 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,486,257 - 169,499,268 (-)Ensemblrn6Rnor6.0
Rnor_5.05173,039,837 - 173,054,032 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45169,537,947 - 169,550,915 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5161,046,593 - 161,066,093 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:25281747   PMID:35352799  


Genomics

Comparative Map Data
Rnf207
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85168,098,074 - 168,112,585 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5168,097,456 - 168,111,094 (-)EnsemblGRCr8
mRatBN7.25162,815,351 - 162,828,325 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,815,357 - 162,828,375 (-)EnsemblmRatBN7.2
Rnor_6.05169,486,253 - 169,500,451 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,486,257 - 169,499,268 (-)Ensemblrn6Rnor6.0
Rnor_5.05173,039,837 - 173,054,032 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45169,537,947 - 169,550,915 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5161,046,593 - 161,066,093 (-)NCBICelera
Cytogenetic Map5q36NCBI
RNF207
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816,206,119 - 6,221,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16,205,475 - 6,221,299 (+)Ensemblhg38GRCh38
GRCh3716,266,179 - 6,281,359 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,188,776 - 6,203,946 (+)NCBIBuild 36Build 36hg18NCBI36
Celera15,380,701 - 5,395,870 (+)NCBICelera
Cytogenetic Map1p36.31NCBI
HuRef15,414,459 - 5,429,630 (+)NCBIHuRef
CHM1_116,254,831 - 6,270,001 (+)NCBICHM1_1
T2T-CHM13v2.015,731,763 - 5,746,943 (+)NCBIT2T-CHM13v2.0
Rnf207
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394152,391,475 - 152,403,686 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4152,391,476 - 152,403,450 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384152,307,018 - 152,319,076 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4152,307,019 - 152,318,993 (-)Ensemblmm10GRCm38
MGSCv374151,681,132 - 151,692,734 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364151,150,823 - 151,162,408 (-)NCBIMGSCv36mm8
Celera4154,594,355 - 154,605,972 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map483.02NCBI
RNF207
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21222,003,165 - 222,017,435 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,645,979 - 220,658,899 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v014,972,787 - 4,986,992 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.116,228,829 - 6,242,778 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16,229,241 - 6,242,770 (+)EnsemblpanPan2panpan1.1
RNF207
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1560,105,200 - 60,119,902 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl560,106,297 - 60,118,670 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha560,114,909 - 60,129,921 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0560,320,633 - 60,335,661 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl560,321,442 - 60,335,653 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1560,320,217 - 60,335,203 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0560,187,028 - 60,202,012 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0560,588,433 - 60,603,475 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rnf207
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505830,580,768 - 30,596,429 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366231,066,957 - 1,079,030 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366231,065,260 - 1,079,918 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF207
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl667,106,552 - 67,116,510 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1667,105,347 - 67,119,167 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2662,013,475 - 62,024,064 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF207
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120125,518,231 - 125,530,249 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605429,624,482 - 29,638,653 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf207
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248185,178,299 - 5,183,610 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248185,176,316 - 5,183,610 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf207
34 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:67
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000046552
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat

Markers in Region
RH143233  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85168,104,914 - 168,105,104 (+)Marker Load Pipeline
mRatBN7.25162,822,191 - 162,822,381 (+)MAPPERmRatBN7.2
Rnor_6.05169,493,094 - 169,493,283NCBIRnor6.0
Rnor_5.05173,046,678 - 173,046,867UniSTSRnor5.0
RGSC_v3.45169,544,784 - 169,544,973UniSTSRGSC3.4
Celera5161,053,434 - 161,053,623UniSTS
RH 3.4 Map51141.1UniSTS
Cytogenetic Map5q36UniSTS
AI705792  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25162,815,512 - 162,815,688 (+)MAPPERmRatBN7.2
Rnor_6.05169,486,415 - 169,486,590NCBIRnor6.0
Rnor_5.05173,039,999 - 173,040,174UniSTSRnor5.0
RGSC_v3.45169,538,105 - 169,538,280UniSTSRGSC3.4
Celera5161,046,755 - 161,046,930UniSTS
RH 3.4 Map51139.0UniSTS
Cytogenetic Map5q36UniSTS
AW525290  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25162,821,760 - 162,821,942 (+)MAPPERmRatBN7.2
Rnor_6.05169,492,663 - 169,492,844NCBIRnor6.0
Rnor_5.05173,046,247 - 173,046,428UniSTSRnor5.0
RGSC_v3.45169,544,353 - 169,544,534UniSTSRGSC3.4
Celera5161,053,003 - 161,053,184UniSTS
RH 3.4 Map51141.3UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 65 158 90 89 58 85 58 6 346 183 11 135 81 91 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000046552   ⟹   ENSRNOP00000047020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5168,097,456 - 168,111,094 (-)Ensembl
mRatBN7.2 Ensembl5162,815,357 - 162,828,375 (-)Ensembl
Rnor_6.0 Ensembl5169,486,257 - 169,499,268 (-)Ensembl
RefSeq Acc Id: XM_001075996   ⟹   XP_001075996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,098,074 - 168,112,585 (-)NCBI
mRatBN7.25162,815,351 - 162,828,325 (-)NCBI
Rnor_6.05169,486,253 - 169,500,451 (-)NCBI
Rnor_5.05173,039,837 - 173,054,032 (-)NCBI
RGSC_v3.45169,537,947 - 169,550,915 (-)RGD
Sequence:
RefSeq Acc Id: XM_008764392   ⟹   XP_008762614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,098,074 - 168,112,585 (-)NCBI
mRatBN7.25162,815,351 - 162,828,325 (-)NCBI
Rnor_6.05169,486,253 - 169,500,451 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039111530   ⟹   XP_038967458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,098,074 - 168,112,585 (-)NCBI
mRatBN7.25162,815,351 - 162,828,325 (-)NCBI
RefSeq Acc Id: XM_039111531   ⟹   XP_038967459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,098,074 - 168,112,585 (-)NCBI
mRatBN7.25162,815,351 - 162,828,325 (-)NCBI
RefSeq Acc Id: XM_039111532   ⟹   XP_038967460
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,098,074 - 168,112,585 (-)NCBI
mRatBN7.25162,815,351 - 162,828,325 (-)NCBI
RefSeq Acc Id: XM_039111534   ⟹   XP_038967462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,103,154 - 168,112,585 (-)NCBI
mRatBN7.25162,820,764 - 162,828,325 (-)NCBI
RefSeq Acc Id: XM_039111535   ⟹   XP_038967463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,103,154 - 168,112,585 (-)NCBI
mRatBN7.25162,820,498 - 162,828,325 (-)NCBI
RefSeq Acc Id: XM_063288668   ⟹   XP_063144738
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,098,074 - 168,105,902 (-)NCBI
RefSeq Acc Id: XP_001075996   ⟸   XM_001075996
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008762614   ⟸   XM_008764392
- Peptide Label: isoform X4
- Sequence:
Ensembl Acc Id: ENSRNOP00000047020   ⟸   ENSRNOT00000046552
RefSeq Acc Id: XP_038967458   ⟸   XM_039111530
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038967460   ⟸   XM_039111532
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038967459   ⟸   XM_039111531
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038967463   ⟸   XM_039111535
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038967462   ⟸   XM_039111534
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063144738   ⟸   XM_063288668
- Peptide Label: isoform X8
Protein Domains
B box-type   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A306-F1-model_v2 AlphaFold D4A306 1-635 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694316
Promoter ID:EPDNEW_R4828
Type:single initiation site
Name:Rnf207_1
Description:ring finger protein 207
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05169,499,282 - 169,499,342EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586262 AgrOrtholog
BioCyc Gene G2FUF-39014 BioCyc
Ensembl Genes ENSRNOG00000033722 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046552 ENTREZGENE
  ENSRNOT00000046552.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Actin interacting protein 3, C-terminal domain UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro PML-like_CC UniProtKB/TrEMBL
  RNF207 UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report rno:691246 UniProtKB/TrEMBL
NCBI Gene 691246 ENTREZGENE
PANTHER PTHR22635 UniProtKB/TrEMBL
  RING FINGER PROTEIN 207 UniProtKB/TrEMBL
Pfam DUF3583 UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PhenoGen Rnf207 PhenoGen
PROSITE ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033722 RatGTEx
SMART BBOX UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt D4A306 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Rnf207  ring finger protein 207  LOC691246  similar to tripartite motif-containing 56  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC691246  similar to tripartite motif-containing 56  LOC686983  similar to tripartite motif-containing 56  Data merged from RGD:1591238 1643240 APPROVED
2006-11-20 LOC686983  similar to tripartite motif-containing 56      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC691246  similar to tripartite motif-containing 56      Symbol and Name status set to provisional 70820 PROVISIONAL