Meis1 (Meis homeobox 1) - Rat Genome Database

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Gene: Meis1 (Meis homeobox 1) Rattus norvegicus
Analyze
Symbol: Meis1
Name: Meis homeobox 1
RGD ID: 1585482
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in cell growth involved in cardiac muscle cell development. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Orthologous to human MEIS1 (Meis homeobox 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeobox protein Meis1; LOC108352805; LOC686117; Meis1, myeloid ecotropic viral integration site 1 homolog; similar to myeloid ecotropic viral integration site 1; uncharacterized LOC108352805
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81497,356,949 - 97,499,646 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1497,322,748 - 97,495,083 (-)EnsemblGRCr8
mRatBN7.21493,155,426 - 93,294,373 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1493,155,419 - 93,294,265 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1497,471,782 - 97,610,378 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01498,716,059 - 98,854,667 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01495,181,092 - 95,319,673 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014103,182,178 - 103,321,809 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14103,181,281 - 103,321,270 (-)Ensemblrn6Rnor6.0
Rnor_5.014102,927,220 - 103,064,633 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41499,693,567 - 99,832,273 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1492,182,045 - 92,319,516 (-)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-adrenaline  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
9-cis-retinoic acid  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-4-oxoretinol  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
chloroethene  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
Evodiamine  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
hexadecanoic acid  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
Licochalcone B  (ISO)
malathion  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mifepristone  (EXP)
nickel atom  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
Ptaquiloside  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sulfadimethoxine  (EXP)
temozolomide  (ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trametinib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Effect of changes in food consistency on NADH-ubiquinone oxidoreductase activity and levels of mRNA for ND1, 51kDa, 75kDa and myosin heavy chain isoforms in two different portions of rat masseter muscle. Ide Y and Sato I, Okajimas Folia Anat Jpn. 2006 Aug;83(2):61-71.
3. MicroRNAs regulating meis1 expression and inducing cardiomyocyte proliferation. Pandey R, etal., Cardiovasc Regen Med. 2016;3. pii: e1468.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Meis1 promotes poly (rC)-binding protein 2 expression and inhibits angiotensin II-induced cardiomyocyte hypertrophy. Zhang Y, etal., IUBMB Life. 2016 Jan;68(1):13-22. doi: 10.1002/iub.1456. Epub 2015 Nov 24.
Additional References at PubMed
PMID:9315626   PMID:9343407   PMID:9405651   PMID:10373562   PMID:10842069   PMID:11438208   PMID:12183364   PMID:12477932   PMID:14713950   PMID:15465489   PMID:15617687   PMID:15634706  
PMID:15882575   PMID:17049510   PMID:17056599   PMID:17178831   PMID:18164701   PMID:19268698   PMID:19799567   PMID:20203303   PMID:21059917   PMID:24642863   PMID:26550823   PMID:32450174  


Genomics

Comparative Map Data
Meis1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81497,356,949 - 97,499,646 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1497,322,748 - 97,495,083 (-)EnsemblGRCr8
mRatBN7.21493,155,426 - 93,294,373 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1493,155,419 - 93,294,265 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1497,471,782 - 97,610,378 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01498,716,059 - 98,854,667 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01495,181,092 - 95,319,673 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.014103,182,178 - 103,321,809 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14103,181,281 - 103,321,270 (-)Ensemblrn6Rnor6.0
Rnor_5.014102,927,220 - 103,064,633 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41499,693,567 - 99,832,273 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1492,182,045 - 92,319,516 (-)NCBICelera
Cytogenetic Map14q22NCBI
MEIS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38266,435,125 - 66,573,869 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl266,433,452 - 66,573,898 (+)Ensemblhg38GRCh38
GRCh37266,662,257 - 66,801,001 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36266,516,036 - 66,653,395 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34266,574,182 - 66,711,541NCBI
Celera266,510,942 - 66,648,316 (+)NCBICelera
Cytogenetic Map2p14NCBI
HuRef266,397,888 - 66,535,182 (+)NCBIHuRef
CHM1_1266,593,726 - 66,731,071 (+)NCBICHM1_1
T2T-CHM13v2.0266,444,205 - 66,582,943 (+)NCBIT2T-CHM13v2.0
Meis1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391118,830,428 - 18,968,992 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1118,829,817 - 18,968,985 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381118,880,428 - 19,019,651 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1118,879,817 - 19,018,985 (-)Ensemblmm10GRCm38
MGSCv371118,780,431 - 18,918,683 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361118,780,431 - 18,918,683 (-)NCBIMGSCv36mm8
Celera1121,034,144 - 21,171,771 (-)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1111.11NCBI
Meis1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542418,058,004 - 18,190,453 (-)Ensembl
ChiLan1.0NW_00495542418,060,499 - 18,190,425 (-)NCBIChiLan1.0ChiLan1.0
MEIS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21259,830,340 - 59,968,706 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A59,833,083 - 59,972,676 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A66,494,934 - 66,633,295 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A67,615,941 - 67,752,958 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A67,615,941 - 67,752,958 (+)EnsemblpanPan2panpan1.1
MEIS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11065,765,498 - 65,898,714 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1065,683,560 - 65,897,573 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1065,654,860 - 65,820,227 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01066,778,156 - 66,943,912 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1066,778,687 - 66,927,290 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11066,456,570 - 66,622,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01066,764,024 - 66,929,260 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01067,059,265 - 67,224,762 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Meis1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629217,354,842 - 17,491,236 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649111,079,455 - 11,217,388 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649111,079,574 - 11,216,451 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEIS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl375,485,022 - 75,625,040 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1375,485,024 - 75,625,855 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2379,331,016 - 79,362,238 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MEIS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11440,473,148 - 40,613,245 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1440,471,063 - 40,611,071 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604571,303,335 - 71,444,475 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Meis1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247626,873,913 - 7,031,346 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247626,894,332 - 7,031,354 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Meis1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11187,166,329 - 87,306,935 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Meis1
556 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:405
Count of miRNA genes:229
Interacting mature miRNAs:281
Transcripts:ENSRNOT00000006157
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582201Sffal2Serum free fatty acids level QTL 240.0002blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)1496755448100078267Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)1486271332100078267Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 67 162 91 90 59 92 59 6 355 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006157   ⟹   ENSRNOP00000006157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1497,356,957 - 97,495,083 (-)Ensembl
mRatBN7.2 Ensembl1493,155,435 - 93,291,701 (-)Ensembl
Rnor_6.0 Ensembl14103,181,281 - 103,321,270 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098187   ⟹   ENSRNOP00000083074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1497,322,748 - 97,495,083 (-)Ensembl
mRatBN7.2 Ensembl1493,178,917 - 93,293,720 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104415   ⟹   ENSRNOP00000089570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1497,356,903 - 97,495,083 (-)Ensembl
mRatBN7.2 Ensembl1493,155,435 - 93,294,260 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107521   ⟹   ENSRNOP00000097699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1493,155,419 - 93,294,265 (-)Ensembl
RefSeq Acc Id: NM_001134702   ⟹   NP_001128174
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,495,083 (-)NCBI
mRatBN7.21493,155,433 - 93,293,595 (-)NCBI
Rnor_6.014103,182,178 - 103,321,129 (-)NCBI
Rnor_5.014102,927,220 - 103,064,633 (-)NCBI
RGSC_v3.41499,693,567 - 99,832,273 (-)RGD
Celera1492,182,045 - 92,319,516 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251529   ⟹   XP_006251591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,497,391 (-)NCBI
mRatBN7.21493,155,426 - 93,294,373 (-)NCBI
Rnor_6.014103,182,178 - 103,321,809 (-)NCBI
Rnor_5.014102,927,220 - 103,064,633 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092454   ⟹   XP_038948382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,360,334 - 97,497,391 (-)NCBI
mRatBN7.21493,155,426 - 93,294,373 (-)NCBI
RefSeq Acc Id: XM_039092455   ⟹   XP_038948383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,487,583 (-)NCBI
mRatBN7.21493,155,426 - 93,286,102 (-)NCBI
RefSeq Acc Id: XM_063273628   ⟹   XP_063129698
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,497,391 (-)NCBI
RefSeq Acc Id: XM_063273629   ⟹   XP_063129699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,499,646 (-)NCBI
RefSeq Acc Id: XM_063273630   ⟹   XP_063129700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,360,334 - 97,497,391 (-)NCBI
RefSeq Acc Id: XR_005493013
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,360,738 - 97,497,391 (-)NCBI
mRatBN7.21493,159,227 - 93,294,373 (-)NCBI
RefSeq Acc Id: NP_001128174   ⟸   NM_001134702
- UniProtKB: B1WC31 (UniProtKB/TrEMBL),   F7EL40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251591   ⟸   XM_006251529
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000006157   ⟸   ENSRNOT00000006157
RefSeq Acc Id: XP_038948382   ⟸   XM_039092454
- Peptide Label: isoform X4
- UniProtKB: B1WC31 (UniProtKB/TrEMBL),   F7EL40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948383   ⟸   XM_039092455
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000097699   ⟸   ENSRNOT00000107521
Ensembl Acc Id: ENSRNOP00000089570   ⟸   ENSRNOT00000104415
Ensembl Acc Id: ENSRNOP00000083074   ⟸   ENSRNOT00000098187
RefSeq Acc Id: XP_063129699   ⟸   XM_063273629
- Peptide Label: isoform X3
- UniProtKB: A6JQ06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129698   ⟸   XM_063273628
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063129700   ⟸   XM_063273630
- Peptide Label: isoform X5
- UniProtKB: F7EL40 (UniProtKB/TrEMBL)
Protein Domains
Homeobox

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WC31-F1-model_v2 AlphaFold B1WC31 1-390 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699506
Promoter ID:EPDNEW_R10030
Type:initiation region
Name:Meis1_1
Description:Meis homeobox 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014103,321,293 - 103,321,353EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1585482 AgrOrtholog
BioCyc Gene G2FUF-14914 BioCyc
Ensembl Genes ENSRNOG00000004606 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006157 ENTREZGENE
  ENSRNOT00000006157.7 UniProtKB/TrEMBL
  ENSRNOT00000098187.2 UniProtKB/TrEMBL
  ENSRNOT00000104415 ENTREZGENE
  ENSRNOT00000104415.2 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9030600 IMAGE-MGC_LOAD
InterPro Homeobox UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  PKNOX/Meis_N UniProtKB/TrEMBL
  TALE_homeobox UniProtKB/TrEMBL
KEGG Report rno:686117 UniProtKB/TrEMBL
MGC_CLONE MGC:187802 IMAGE-MGC_LOAD
NCBI Gene 686117 ENTREZGENE
PANTHER HOMEOBOX PROTEIN TRANSCRIPTION FACTORS UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
  Meis_PKNOX_N UniProtKB/TrEMBL
PhenoGen Meis1 PhenoGen
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004606 RatGTEx
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A0A8I5ZVB5_RAT UniProtKB/TrEMBL
  A0A8I6GI80_RAT UniProtKB/TrEMBL
  A0A8I6GMM6 ENTREZGENE
  A6JQ06 ENTREZGENE, UniProtKB/TrEMBL
  B1WC31 ENTREZGENE, UniProtKB/TrEMBL
  F7EL40 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Meis1  Meis homeobox 1  LOC108352805  uncharacterized LOC108352805  Data merged from RGD:11361306 737654 PROVISIONAL
2016-08-02 LOC108352805  uncharacterized LOC108352805      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-18 Meis1  Meis homeobox 1   LOC686117  similar to myeloid ecotropic viral integration site 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC686117  similar to myeloid ecotropic viral integration site 1  LOC679409  similar to Homeobox protein Meis1 (Myeloid ecotropic viral integration site 1)  Data merged from RGD:1588354 1643240 APPROVED
2006-11-19 LOC686117  similar to myeloid ecotropic viral integration site 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC679409  similar to Homeobox protein Meis1 (Myeloid ecotropic viral integration site 1)      Symbol and Name status set to provisional 70820 PROVISIONAL