Cyssl3 (cystatin S like 3) - Rat Genome Database

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Pathways
Gene: Cyssl3 (cystatin S like 3) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Cyssl3
Name: cystatin S like 3
RGD ID: 1566383
Description: INTERACTS WITH 17beta-estradiol; testosterone
Type: ncrna
RefSeq Status: VALIDATED
Previously known as: LOC362233; RGD1566383; similar to Cystatin S precursor (LM protein)
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83157,931,010 - 157,934,458 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.23137,470,409 - 137,473,857 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx3141,404,391 - 141,407,835 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03149,988,082 - 149,991,526 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03147,703,403 - 147,706,851 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03144,464,989 - 144,470,874 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03150,839,064 - 150,844,949 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43138,864,545 - 138,867,862 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3136,156,083 - 136,161,481 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Cyssl3
33 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat

Markers in Region
D3Rat245  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83157,931,188 - 157,931,434 (+)Marker Load Pipeline
mRatBN7.23137,470,587 - 137,470,833 (+)MAPPERmRatBN7.2
Rnor_6.03144,466,145 - 144,466,390NCBIRnor6.0
Rnor_5.03150,840,220 - 150,840,465UniSTSRnor5.0
RGSC_v3.43138,864,636 - 138,864,881UniSTSRGSC3.4
RGSC_v3.43138,864,635 - 138,864,881RGDRGSC3.4
RGSC_v3.13138,770,208 - 138,770,454RGD
SHRSP x BN Map365.5899UniSTS
SHRSP x BN Map365.5899RGD
FHH x ACI Map382.4399RGD
Cytogenetic Map3q41UniSTS


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: NR_144435
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83157,931,010 - 157,934,458 (+)NCBI
mRatBN7.23137,470,409 - 137,473,857 (+)NCBI
Protein Sequences
GenBank Protein EDL95065 (Get FASTA)   NCBI Sequence Viewer  


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566383 AgrOrtholog
BioCyc Gene G2FUF-47465 BioCyc
NCBI Gene 362233 ENTREZGENE
PhenoGen Cyssl3 PhenoGen
RNAcentral URS0000A7643F RNACentral
  URS0000CCF41D RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Cyssl3  cystatin S like 3  RGD1566383  similar to Cystatin S precursor (LM protein)  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1566383  similar to Cystatin S precursor (LM protein)   RGD1566383_predicted  similar to Cystatin S precursor (LM protein) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1566383_predicted  similar to Cystatin S precursor (LM protein) (predicted)  LOC362233  similar to Cystatin S precursor (LM protein)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC362233  similar to Cystatin S precursor (LM protein)      Symbol and Name status set to provisional 70820 PROVISIONAL