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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Btbd2 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BTBD2 mRNA] | CTD | PMID:31150632 | Btbd2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Btbd2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTBD2 mRNA | CTD | PMID:22206623 | Btbd2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Btbd2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of BTBD2 mRNA | CTD | PMID:22206623 | Btbd2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Btbd2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of BTBD2 mRNA | CTD | PMID:21354282 | Btbd2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of BTBD2 mRNA | CTD | PMID:26232522 and PMID:33387578 | Btbd2 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Btbd2 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of BTBD2 mRNA | CTD | PMID:20188158 | Btbd2 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of BTBD2 mRNA | CTD | PMID:30047161 | Btbd2 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of BTBD2 mRNA | CTD | PMID:30047161 | Btbd2 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of BTBD2 mRNA | CTD | PMID:30779732 | Btbd2 | Rat | aristolochic acid A | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of BTBD2 mRNA | CTD | PMID:33212167 | Btbd2 | Rat | arsenous acid | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of BTBD2 mRNA | CTD | PMID:15725085 | Btbd2 | Rat | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of BTBD2 mRNA | CTD | PMID:21839799 | Btbd2 | Rat | benzo[a]pyrene | increases methylation | ISO | BTBD2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of BTBD2 promoter | CTD | PMID:27901495 | Btbd2 | Rat | benzo[a]pyrene | decreases methylation | ISO | BTBD2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of BTBD2 3' UTR | CTD | PMID:27901495 | Btbd2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of BTBD2 mRNA | CTD | PMID:25181051 | Btbd2 | Rat | bisphenol A | increases expression | ISO | Btbd2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of BTBD2 mRNA | CTD | PMID:32156529 | Btbd2 | Rat | bisphenol A | decreases methylation | ISO | BTBD2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of BTBD2 gene | CTD | PMID:31601247 | Btbd2 | Rat | bisphenol A | affects expression | ISO | BTBD2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of BTBD2 mRNA | CTD | PMID:30903817 | Btbd2 | Rat | bisphenol A | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of BTBD2 mRNA | CTD | PMID:25912373 | Btbd2 | Rat | bisphenol AF | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | bisphenol AF results in decreased expression of BTBD2 mRNA | CTD | PMID:25912373 | Btbd2 | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of BTBD2 mRNA | CTD | PMID:19167457 | Btbd2 | Rat | carbon nanotube | decreases expression | ISO | Btbd2 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of BTBD2 mRNA | CTD | PMID:25554681 and PMID:25620056 | Btbd2 | Rat | CGP 52608 | multiple interactions | ISO | BTBD2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to BTBD2 gene] | CTD | PMID:28238834 | Btbd2 | Rat | chlorpyrifos | increases expression | ISO | Btbd2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of BTBD2 mRNA | CTD | PMID:37019170 | Btbd2 | Rat | clobetasol | increases expression | ISO | Btbd2 (Mus musculus) | 6480464 | Clobetasol results in increased expression of BTBD2 mRNA | CTD | PMID:27462272 | Btbd2 | Rat | clofibrate | decreases expression | ISO | Btbd2 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of BTBD2 mRNA | CTD | PMID:23811191 | Btbd2 | Rat | copper(II) chloride | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | cupric chloride results in decreased expression of BTBD2 mRNA | CTD | PMID:38568856 | Btbd2 | Rat | cyclosporin A | decreases methylation | ISO | BTBD2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of BTBD2 promoter | CTD | PMID:27989131 | Btbd2 | Rat | diarsenic trioxide | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of BTBD2 mRNA | CTD | PMID:15725085 | Btbd2 | Rat | Dibutyl phosphate | affects expression | ISO | BTBD2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of BTBD2 mRNA | CTD | PMID:37042841 | Btbd2 | Rat | diethyl maleate | decreases expression | EXP | | 6480464 | diethyl maleate results in decreased expression of BTBD2 mRNA | CTD | PMID:21161181 | Btbd2 | Rat | ethanol | affects splicing | ISO | Btbd2 (Mus musculus) | 6480464 | Ethanol affects the splicing of BTBD2 mRNA | CTD | PMID:30319688 | Btbd2 | Rat | folic acid | multiple interactions | ISO | Btbd2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BTBD2 mRNA | CTD | PMID:22206623 | Btbd2 | Rat | hypochlorous acid | decreases expression | ISO | Btbd2 (Mus musculus) | 6480464 | Hypochlorous Acid results in decreased expression of BTBD2 mRNA | CTD | PMID:19376150 | Btbd2 | Rat | nickel sulfate | increases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of BTBD2 mRNA | CTD | PMID:22714537 | Btbd2 | Rat | paracetamol | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of BTBD2 mRNA | CTD | PMID:26690555 | Btbd2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of BTBD2 mRNA | CTD | PMID:33387578 | Btbd2 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of BTBD2 mRNA | CTD | PMID:32680482 | Btbd2 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of BTBD2 mRNA | CTD | PMID:30047161 | Btbd2 | Rat | quercetin | increases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of BTBD2 mRNA | CTD | PMID:21632981 | Btbd2 | Rat | sodium arsenite | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of BTBD2 mRNA | CTD | PMID:38568856 | Btbd2 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of BTBD2 mRNA | CTD | PMID:15336504 | Btbd2 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BTBD2 mRNA] | CTD | PMID:31150632 | Btbd2 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of BTBD2 mRNA | CTD | PMID:31150632 | Btbd2 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of BTBD2 mRNA | CTD | PMID:34492290 | Btbd2 | Rat | thiram | decreases expression | ISO | BTBD2 (Homo sapiens) | 6480464 | Thiram results in decreased expression of BTBD2 mRNA | CTD | PMID:38568856 | Btbd2 | Rat | valproic acid | increases methylation | ISO | BTBD2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of BTBD2 gene | CTD | PMID:29154799 | Btbd2 | Rat | zinc atom | affects expression | ISO | BTBD2 (Homo sapiens) | 6480464 | Zinc affects the expression of BTBD2 mRNA | CTD | PMID:16979875 | Btbd2 | Rat | zinc(0) | affects expression | ISO | BTBD2 (Homo sapiens) | 6480464 | Zinc affects the expression of BTBD2 mRNA | CTD | PMID:16979875 | |