Mettl5 (methyltransferase 5, N6-adenosine) - Rat Genome Database

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Gene: Mettl5 (methyltransferase 5, N6-adenosine) Rattus norvegicus
Analyze
Symbol: Mettl5
Name: methyltransferase 5, N6-adenosine
RGD ID: 1566062
Description: Predicted to enable S-adenosyl-L-methionine binding activity and rRNA (adenine-N6-)-methyltransferase activity. Predicted to be involved in positive regulation of translation; rRNA methylation; and stem cell differentiation. Predicted to be located in several cellular components, including fibrillar center; postsynapse; and presynapse. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 72. Orthologous to human METTL5 (methyltransferase 5, N6-adenosine); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC502632; methyltransferase like 5; methyltransferase-like protein 5; MGC187943; RGD1566062; rRNA N6-adenosine-methyltransferase METTL5; similar to 2810410A08Rik protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8375,033,605 - 75,046,359 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl375,026,861 - 75,045,831 (-)EnsemblGRCr8
mRatBN7.2354,625,790 - 54,638,066 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl354,625,793 - 54,638,039 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx358,027,311 - 58,039,545 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0366,610,906 - 66,623,143 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0364,373,285 - 64,385,524 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0356,101,597 - 56,113,823 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl356,101,580 - 56,113,857 (-)Ensemblrn6Rnor6.0
Rnor_5.0362,736,605 - 62,747,462 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4352,010,202 - 52,022,428 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera354,185,280 - 54,197,536 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA,ISO)
fibrillar center  (IEA,ISO)
nucleolus  (IEA,ISO)
nucleus  (IEA,ISO)
postsynapse  (IEA,ISO)
presynapse  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:31328227   PMID:31564433  


Genomics

Comparative Map Data
Mettl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8375,033,605 - 75,046,359 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl375,026,861 - 75,045,831 (-)EnsemblGRCr8
mRatBN7.2354,625,790 - 54,638,066 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl354,625,793 - 54,638,039 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx358,027,311 - 58,039,545 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0366,610,906 - 66,623,143 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0364,373,285 - 64,385,524 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0356,101,597 - 56,113,823 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl356,101,580 - 56,113,857 (-)Ensemblrn6Rnor6.0
Rnor_5.0362,736,605 - 62,747,462 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4352,010,202 - 52,022,428 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera354,185,280 - 54,197,536 (-)NCBICelera
Cytogenetic Map3q21NCBI
METTL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382169,811,757 - 169,824,905 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2169,810,081 - 169,824,931 (-)Ensemblhg38GRCh38
GRCh372170,668,267 - 170,681,415 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362170,376,513 - 170,389,599 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2164,284,639 - 164,297,724 (-)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2162,556,329 - 162,569,341 (-)NCBIHuRef
CHM1_12170,674,123 - 170,687,225 (-)NCBICHM1_1
T2T-CHM13v2.02170,289,301 - 170,302,459 (-)NCBIT2T-CHM13v2.0
Mettl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39269,701,539 - 69,717,961 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl269,701,542 - 69,715,959 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38269,871,195 - 69,886,634 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl269,871,198 - 69,885,615 (-)Ensemblmm10GRCm38
MGSCv37269,709,252 - 69,723,661 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36269,672,034 - 69,686,454 (-)NCBIMGSCv36mm8
Celera271,541,239 - 71,555,439 (-)NCBICelera
Cytogenetic Map2C2NCBI
cM Map240.95NCBI
Mettl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554494,795,925 - 4,806,847 (+)Ensembl
ChiLan1.0NW_0049554494,795,925 - 4,806,757 (+)NCBIChiLan1.0ChiLan1.0
METTL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21372,472,145 - 72,485,453 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B72,487,133 - 72,500,424 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B57,084,128 - 57,097,402 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B174,549,310 - 174,562,269 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B174,547,888 - 174,562,254 (-)EnsemblpanPan2panpan1.1
METTL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13614,476,493 - 14,483,553 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3614,475,186 - 14,483,502 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3614,488,088 - 14,495,268 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03614,595,355 - 14,602,541 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3614,593,956 - 14,602,515 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13614,678,173 - 14,685,354 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03614,670,440 - 14,677,620 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03614,782,152 - 14,789,334 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mettl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303131,741,419 - 131,752,242 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936509290,675 - 306,203 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936509295,441 - 306,154 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
METTL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1576,092,968 - 76,108,351 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11576,097,873 - 76,108,362 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21585,206,086 - 85,225,159 (-)NCBISscrofa10.2Sscrofa10.2susScr3
METTL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11055,339,009 - 55,352,353 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1055,337,029 - 55,351,857 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040144,184,517 - 144,197,134 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mettl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247877,299,893 - 7,313,031 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247877,300,540 - 7,312,604 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Mettl5
25 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:157
Count of miRNA genes:104
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000011303
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)35318459364655484Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat

Markers in Region
AI232705  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2354,625,630 - 54,625,850 (+)MAPPERmRatBN7.2
Rnor_6.0356,101,438 - 56,101,657NCBIRnor6.0
Rnor_5.0362,736,446 - 62,736,665UniSTSRnor5.0
RGSC_v3.4352,010,043 - 52,010,262UniSTSRGSC3.4
Celera354,185,121 - 54,185,340UniSTS
Cytogenetic Map3q24-q32UniSTS
Cytogenetic Map3q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011303   ⟹   ENSRNOP00000011304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl375,033,608 - 75,045,831 (-)Ensembl
mRatBN7.2 Ensembl354,625,793 - 54,638,019 (-)Ensembl
Rnor_6.0 Ensembl356,101,580 - 56,113,857 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099579   ⟹   ENSRNOP00000094502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl375,034,790 - 75,045,831 (-)Ensembl
mRatBN7.2 Ensembl354,627,112 - 54,638,039 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000126848   ⟹   ENSRNOP00000110281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl375,032,234 - 75,045,831 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000130192   ⟹   ENSRNOP00000106949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl375,026,861 - 75,045,831 (-)Ensembl
RefSeq Acc Id: NM_001114181   ⟹   NP_001107653
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,033,605 - 75,045,831 (-)NCBI
mRatBN7.2354,625,790 - 54,638,019 (-)NCBI
Rnor_6.0356,101,597 - 56,113,823 (-)NCBI
Rnor_5.0362,736,605 - 62,747,462 (-)NCBI
RGSC_v3.4352,010,202 - 52,022,428 (-)RGD
Celera354,185,280 - 54,197,536 (-)RGD
Sequence:
RefSeq Acc Id: XM_039105726   ⟹   XP_038961654
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,035,032 - 75,045,878 (-)NCBI
mRatBN7.2354,626,553 - 54,638,066 (-)NCBI
RefSeq Acc Id: XM_063284400   ⟹   XP_063140470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,033,704 - 75,045,878 (-)NCBI
RefSeq Acc Id: XM_063284401   ⟹   XP_063140471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8375,033,704 - 75,046,359 (-)NCBI
RefSeq Acc Id: NP_001107653   ⟸   NM_001114181
- UniProtKB: B0BNB3 (UniProtKB/TrEMBL),   A6HM25 (UniProtKB/TrEMBL),   F7FIR4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011304   ⟸   ENSRNOT00000011303
RefSeq Acc Id: XP_038961654   ⟸   XM_039105726
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000094502   ⟸   ENSRNOT00000099579
RefSeq Acc Id: XP_063140471   ⟸   XM_063284401
- Peptide Label: isoform X2
- UniProtKB: A6HM25 (UniProtKB/TrEMBL),   B0BNB3 (UniProtKB/TrEMBL),   F7FIR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140470   ⟸   XM_063284400
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000106949   ⟸   ENSRNOT00000130192
Ensembl Acc Id: ENSRNOP00000110281   ⟸   ENSRNOT00000126848
Protein Domains
Methyltransferase small

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BNB3-F1-model_v2 AlphaFold B0BNB3 1-209 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692125
Promoter ID:EPDNEW_R2649
Type:initiation region
Name:Mettl5_1
Description:methyltransferase like 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0356,113,855 - 56,113,915EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566062 AgrOrtholog
BioCyc Gene G2FUF-49496 BioCyc
Ensembl Genes ENSRNOG00000008469 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011303 ENTREZGENE
  ENSRNOT00000011303.6 UniProtKB/TrEMBL
  ENSRNOT00000099579.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9102963 IMAGE-MGC_LOAD
InterPro DNA_methylase_N6_adenine_CS UniProtKB/TrEMBL
  rRNA_MeTrfase/Polyamine_Synth UniProtKB/TrEMBL
  SAM-dependent_MTases-like UniProtKB/TrEMBL
  Small_mtfrase UniProtKB/TrEMBL
KEGG Report rno:502632 UniProtKB/TrEMBL
MGC_CLONE MGC:187943 IMAGE-MGC_LOAD
NCBI Gene 502632 ENTREZGENE
PANTHER RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam MTS UniProtKB/TrEMBL
PhenoGen Mettl5 PhenoGen
PROSITE N6_MTASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008469 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A8I6AKX6_RAT UniProtKB/TrEMBL
  A6HM25 ENTREZGENE, UniProtKB/TrEMBL
  B0BNB3 ENTREZGENE
  F7FIR4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B0BNB3 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-17 Mettl5  methyltransferase 5, N6-adenosine  Mettl5  methyltransferase like 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Mettl5  methyltransferase like 5  RGD1566062_predicted  similar to 2810410A08Rik protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1566062_predicted  similar to 2810410A08Rik protein (predicted)  LOC502632  similar to 2810410A08Rik protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC502632  similar to 2810410A08Rik protein      Symbol and Name status set to provisional 70820 PROVISIONAL