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Gene: Ankrd37 (ankyrin repeat domain 37) Rattus norvegicus

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Symbol:

Ankrd37

Name:

ankyrin repeat domain 37

RGD ID:

1565715

Description:

Predicted to be located in cytosol; mitochondrion; and nucleus. Predicted to be active in cytoplasm. Orthologous to human ANKRD37 (ankyrin repeat domain 37); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ankyrin repeat domain-containing protein 37; LOC361149; RGD1565715; similar to low density lipoprotein receptor-related protein binding protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ANKRD37 (ankyrin repeat domain 37)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ankrd37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ankrd37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ANKRD37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ANKRD37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ankrd37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ANKRD37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ANKRD37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ankrd37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	WDR19 (WD repeat domain 19)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ANKRD37 (ankyrin repeat domain 37)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ankrd37 (ankyrin repeat domain 37)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ankrd37 (ankyrin repeat domain 37)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ankrd37	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	53,001,487 - 53,004,545 (+)	NCBI		GRCr8
mRatBN7.2	16	46,268,933 - 46,271,971 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	46,268,443 - 46,271,963 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	51,670,260 - 51,673,301 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	55,039,437 - 55,042,473 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	50,309,635 - 50,312,676 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	49,463,016 - 49,465,905 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	49,462,889 - 49,465,888 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	49,189,582 - 49,192,471 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	49,549,527 - 49,552,416 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	44,267,470 - 44,270,359 (+)	NCBI		Celera
Cytogenetic Map	16	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ankrd37	Rat	autistic disorder		ISO	RGD:1604164	8554872	ClinVar Annotator: match by term: Autism	ClinVar	PMID:21681106\|PMID:30208311
Ankrd37	Rat	Beukes hip dysplasia		ISO	RGD:1604164	8554872	ClinVar Annotator: match by term: Hip dysplasia, Beukes type	ClinVar	PMID:25741868
Ankrd37	Rat	Cerebral Visual Impairment and Intellectual Disability		ISO	RGD:1604164	8554872	ClinVar Annotator: match by term: Cerebral visual impairment and intellectual disability	ClinVar	PMID:26350515
Ankrd37	Rat	developmental dysplasia of the hip		ISO	RGD:1604164	8554872	ClinVar Annotator: match by term: Developmental dysplasia of the hip	ClinVar	PMID:25741868
Ankrd37	Rat	dilated cardiomyopathy		ISO	RGD:1604164	8554872	ClinVar Annotator: match by term: Primary dilated cardiomyopathy	ClinVar	PMID:28492532
Ankrd37	Rat	Herpes Simplex Encephalitis 1		ISO	RGD:1604164	8554872	ClinVar Annotator: match by term: Herpes simplex encephalitis, susceptibility to, 1	ClinVar	PMID:15042513\|PMID:25118264\|PMID:25629076\|PMID:28492532

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ankrd37	Rat	(-)-demecolcine	decreases expression	ISO	RGD:1604164	6480464	Demecolcine results in decreased expression of ANKRD37 mRNA	CTD	PMID:23649840
Ankrd37	Rat	1,10-phenanthroline	increases expression	ISO	RGD:1604164	6480464	1,10-phenanthroline results in increased expression of ANKRD37 mRNA	CTD	PMID:19502547
Ankrd37	Rat	1,2-dichloroethane	decreases expression	ISO	RGD:1616237	6480464	ethylene dichloride results in decreased expression of ANKRD37 mRNA	CTD	PMID:28960355
Ankrd37	Rat	1,2-dimethylhydrazine	decreases expression	ISO	RGD:1616237	6480464	1,2-Dimethylhydrazine results in decreased expression of ANKRD37 mRNA	CTD	PMID:22206623
Ankrd37	Rat	1-chloro-2,4-dinitrobenzene	increases expression	ISO	RGD:1604164	6480464	Dinitrochlorobenzene results in increased expression of ANKRD37 mRNA	CTD	PMID:25236440
Ankrd37	Rat	17beta-estradiol	decreases expression	ISO	RGD:1604164	6480464	Estradiol results in decreased expression of ANKRD37 mRNA	CTD	PMID:21632981
Ankrd37	Rat	17beta-estradiol	affects expression	EXP		6480464	Estradiol affects the expression of ANKRD37 mRNA	CTD	PMID:32145629
Ankrd37	Rat	17beta-hydroxy-5alpha-androstan-3-one	increases expression	ISO	RGD:1604164	6480464	Dihydrotestosterone results in increased expression of ANKRD37 mRNA	CTD	PMID:29581250
Ankrd37	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1616237	6480464	Tetrachlorodibenzodioxin affects the expression of ANKRD37 mRNA	CTD	PMID:26377647
Ankrd37	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of ANKRD37 mRNA	CTD	PMID:33387578
Ankrd37	Rat	2,4-diaminotoluene	decreases expression	ISO	RGD:1616237	6480464	2,4-diaminotoluene results in decreased expression of ANKRD37 mRNA	CTD	PMID:20713471
Ankrd37	Rat	2-hydroxypropanoic acid	decreases expression	ISO	RGD:1604164	6480464	Lactic Acid results in decreased expression of ANKRD37 mRNA	CTD	PMID:30851411
Ankrd37	Rat	2-palmitoylglycerol	increases expression	ISO	RGD:1604164	6480464	2-palmitoylglycerol results in increased expression of ANKRD37 mRNA	CTD	PMID:37199045
Ankrd37	Rat	3-isobutyl-1-methyl-7H-xanthine	multiple interactions	ISO	RGD:1604164	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression more ...	CTD	PMID:28628672
Ankrd37	Rat	4-hydroxyphenyl retinamide	increases expression	ISO	RGD:1616237	6480464	Fenretinide results in increased expression of ANKRD37 mRNA	CTD	PMID:28973697
Ankrd37	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of ANKRD37 mRNA	CTD	PMID:24780913\|PMID:30047161
Ankrd37	Rat	acrylamide	increases expression	ISO	RGD:1616237	6480464	Acrylamide results in increased expression of ANKRD37 mRNA	CTD	PMID:30807115
Ankrd37	Rat	aflatoxin B1	decreases expression	ISO	RGD:1616237	6480464	Aflatoxin B1 results in decreased expression of ANKRD37 mRNA	CTD	PMID:19770486
Ankrd37	Rat	amitrole	decreases expression	EXP		6480464	Amitrole results in decreased expression of ANKRD37 mRNA	CTD	PMID:30047161
Ankrd37	Rat	amphetamine	increases expression	EXP		6480464	Amphetamine results in increased expression of ANKRD37 mRNA	CTD	PMID:30779732
Ankrd37	Rat	arsane	multiple interactions	ISO	RGD:1604164	6480464	[sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ANKRD37 more ...	CTD	PMID:32525701
Ankrd37	Rat	arsenic atom	multiple interactions	ISO	RGD:1604164	6480464	[sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ANKRD37 more ...	CTD	PMID:32525701
Ankrd37	Rat	arsenite(3-)	increases methylation	ISO	RGD:1604164	6480464	arsenite results in increased methylation of ANKRD37 promoter	CTD	PMID:23974009
Ankrd37	Rat	atrazine	increases expression	ISO	RGD:1604164	6480464	Atrazine results in increased expression of ANKRD37 mRNA	CTD	PMID:22378314
Ankrd37	Rat	benzo[a]pyrene	decreases expression	ISO	RGD:1616237	6480464	Benzo(a)pyrene results in decreased expression of ANKRD37 mRNA	CTD	PMID:20713471
Ankrd37	Rat	benzo[a]pyrene	affects methylation	ISO	RGD:1604164	6480464	Benzo(a)pyrene affects the methylation of ANKRD37 promoter	CTD	PMID:27901495
Ankrd37	Rat	benzo[a]pyrene	multiple interactions	ISO	RGD:1616237	6480464	AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ANKRD37 mRNA]	CTD	PMID:22228805
Ankrd37	Rat	benzo[a]pyrene diol epoxide I	increases expression	ISO	RGD:1604164	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of ANKRD37 mRNA	CTD	PMID:19150397
Ankrd37	Rat	beta-lapachone	increases expression	ISO	RGD:1604164	6480464	beta-lapachone results in increased expression of ANKRD37 mRNA	CTD	PMID:38218311
Ankrd37	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1616237	6480464	Diethylhexyl Phthalate results in decreased expression of ANKRD37 mRNA	CTD	PMID:34319233
Ankrd37	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of ANKRD37 mRNA	CTD	PMID:25181051\|PMID:32145629
Ankrd37	Rat	bisphenol A	decreases expression	ISO	RGD:1616237	6480464	bisphenol A results in decreased expression of ANKRD37 mRNA	CTD	PMID:35479511
Ankrd37	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of ANKRD37 mRNA	CTD	PMID:34947998
Ankrd37	Rat	bisphenol A	affects expression	ISO	RGD:1604164	6480464	bisphenol A affects the expression of ANKRD37 mRNA	CTD	PMID:30903817
Ankrd37	Rat	bisphenol A	increases expression	ISO	RGD:1616237	6480464	bisphenol A results in increased expression of ANKRD37 mRNA	CTD	PMID:25594700
Ankrd37	Rat	bisphenol F	decreases expression	ISO	RGD:1616237	6480464	bisphenol F results in decreased expression of ANKRD37 mRNA	CTD	PMID:38685157
Ankrd37	Rat	cadmium dichloride	increases expression	ISO	RGD:1604164	6480464	Cadmium Chloride results in increased expression of ANKRD37 mRNA	CTD	PMID:38568856
Ankrd37	Rat	caffeine	decreases expression	EXP		6480464	Caffeine results in decreased expression of ANKRD37 mRNA	CTD	PMID:20864626
Ankrd37	Rat	calcitriol	increases expression	ISO	RGD:1604164	6480464	Calcitriol results in increased expression of ANKRD37 mRNA	CTD	PMID:21592394
Ankrd37	Rat	calcitriol	multiple interactions	ISO	RGD:1604164	6480464	[Testosterone co-treated with Calcitriol] results in increased expression of ANKRD37 mRNA	CTD	PMID:21592394
Ankrd37	Rat	carbon nanotube	decreases expression	ISO	RGD:1616237	6480464	Nanotubes, Carbon results in decreased expression of ANKRD37 mRNA	CTD	PMID:25620056
Ankrd37	Rat	carbon nanotube	increases expression	ISO	RGD:1616237	6480464	Nanotubes, Carbon analog results in increased expression of ANKRD37 mRNA; Nanotubes, Carbon results in increased more ...	CTD	PMID:25554681\|PMID:25620056
Ankrd37	Rat	CGP 52608	multiple interactions	ISO	RGD:1604164	6480464	CGP 52608 promotes the reaction [RORA protein binds to ANKRD37 gene]	CTD	PMID:28238834
Ankrd37	Rat	chloroprene	decreases expression	ISO	RGD:1616237	6480464	Chloroprene results in decreased expression of ANKRD37 mRNA	CTD	PMID:23125180
Ankrd37	Rat	chlorpyrifos	increases expression	ISO	RGD:1616237	6480464	Chlorpyrifos results in increased expression of ANKRD37 mRNA	CTD	PMID:37019170
Ankrd37	Rat	clothianidin	decreases expression	ISO	RGD:1604164	6480464	clothianidin results in decreased expression of ANKRD37 mRNA	CTD	PMID:31626844
Ankrd37	Rat	cobalt dichloride	multiple interactions	ISO	RGD:1604164	6480464	zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKRD37 mRNA]	CTD	PMID:22202117
Ankrd37	Rat	cobalt dichloride	increases expression	ISO	RGD:1604164	6480464	cobaltous chloride results in increased expression of ANKRD37 mRNA	CTD	PMID:19502547\|PMID:22202117
Ankrd37	Rat	cobalt dichloride	increases expression	EXP		6480464	cobaltous chloride results in increased expression of ANKRD37 mRNA	CTD	PMID:23814049\|PMID:24386269
Ankrd37	Rat	cobalt(2+) sulfate	increases expression	ISO	RGD:1604164	6480464	cobalt sulfate results in increased expression of ANKRD37 mRNA	CTD	PMID:19502547
Ankrd37	Rat	copper atom	multiple interactions	ISO	RGD:1604164	6480464	[NSC 689534 binds to Copper] which results in increased expression of ANKRD37 mRNA	CTD	PMID:20971185
Ankrd37	Rat	copper(0)	multiple interactions	ISO	RGD:1604164	6480464	[NSC 689534 binds to Copper] which results in increased expression of ANKRD37 mRNA	CTD	PMID:20971185
Ankrd37	Rat	coumarin 460	increases expression	ISO	RGD:1604164	6480464	4-methyl-7-diethylaminocoumarin results in increased expression of ANKRD37 mRNA	CTD	PMID:19502547
Ankrd37	Rat	crotonaldehyde	increases expression	ISO	RGD:1604164	6480464	2-butenal results in increased expression of ANKRD37 mRNA	CTD	PMID:20471460
Ankrd37	Rat	curcumin	decreases expression	ISO	RGD:1604164	6480464	Curcumin results in decreased expression of ANKRD37 mRNA	CTD	PMID:17198877
Ankrd37	Rat	cyclosporin A	affects expression	ISO	RGD:1604164	6480464	Cyclosporine affects the expression of ANKRD37 mRNA	CTD	PMID:20106945
Ankrd37	Rat	cyclosporin A	increases expression	ISO	RGD:1604164	6480464	Cyclosporine results in increased expression of ANKRD37 mRNA	CTD	PMID:27989131
Ankrd37	Rat	cyclosporin A	decreases expression	ISO	RGD:1604164	6480464	Cyclosporine results in decreased expression of ANKRD37 mRNA	CTD	PMID:21632981\|PMID:25562108
Ankrd37	Rat	cyclosporin A	decreases expression	ISO	RGD:1616237	6480464	Cyclosporine results in decreased expression of ANKRD37 mRNA	CTD	PMID:19770486
Ankrd37	Rat	deoxynivalenol	decreases expression	ISO	RGD:1604164	6480464	deoxynivalenol results in decreased expression of ANKRD37 mRNA	CTD	PMID:31863870
Ankrd37	Rat	dexamethasone	multiple interactions	ISO	RGD:1604164	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression more ...	CTD	PMID:28628672
Ankrd37	Rat	dibutyl phthalate	decreases expression	ISO	RGD:1616237	6480464	Dibutyl Phthalate results in decreased expression of ANKRD37 mRNA	CTD	PMID:21266533
Ankrd37	Rat	dioxygen	increases expression	ISO	RGD:1616237	6480464	Oxygen deficiency results in increased expression of ANKRD37 mRNA	CTD	PMID:20880076
Ankrd37	Rat	dioxygen	multiple interactions	ISO	RGD:1616237	6480464	[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ANKRD37 mRNA	CTD	PMID:30529165
Ankrd37	Rat	dioxygen	increases expression	ISO	RGD:1604164	6480464	Oxygen deficiency results in increased expression of ANKRD37 mRNA	CTD	PMID:19502547\|PMID:20042640\|PMID:24236059\|PMID:24403227\|PMID:26516004
Ankrd37	Rat	dioxygen	multiple interactions	ISO	RGD:1604164	6480464	1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Oxygen deficiency results in increased expression of ANKRD37 mRNA]	CTD	PMID:24403227
Ankrd37	Rat	diphenylcyclopropenone	increases expression	ISO	RGD:1604164	6480464	diphenylcyclopropenone results in increased expression of ANKRD37 mRNA	CTD	PMID:25236440
Ankrd37	Rat	dorsomorphin	multiple interactions	ISO	RGD:1604164	6480464	[NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ...	CTD	PMID:27188386
Ankrd37	Rat	endosulfan	affects expression	EXP		6480464	Endosulfan affects the expression of ANKRD37 mRNA	CTD	PMID:29391264
Ankrd37	Rat	entinostat	decreases expression	ISO	RGD:1604164	6480464	entinostat results in decreased expression of ANKRD37 mRNA	CTD	PMID:26272509
Ankrd37	Rat	entinostat	multiple interactions	ISO	RGD:1604164	6480464	[NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ...	CTD	PMID:27188386
Ankrd37	Rat	ethyl methanesulfonate	decreases expression	ISO	RGD:1604164	6480464	Ethyl Methanesulfonate results in decreased expression of ANKRD37 mRNA	CTD	PMID:23649840
Ankrd37	Rat	fluoranthene	multiple interactions	ISO	RGD:1616237	6480464	[1-methylanthracene co-treated with fluoranthene] results in decreased expression of ANKRD37 mRNA	CTD	PMID:28329830
Ankrd37	Rat	formaldehyde	increases expression	ISO	RGD:1604164	6480464	Formaldehyde results in increased expression of ANKRD37 mRNA	CTD	PMID:20655997\|PMID:23416264
Ankrd37	Rat	formaldehyde	decreases expression	ISO	RGD:1604164	6480464	Formaldehyde results in decreased expression of ANKRD37 mRNA	CTD	PMID:23649840
Ankrd37	Rat	GSK-J4	increases expression	ISO	RGD:1604164	6480464	GSK-J4 results in increased expression of ANKRD37 mRNA	CTD	PMID:29301935
Ankrd37	Rat	indole-3-methanol	affects expression	EXP		6480464	indole-3-carbinol affects the expression of ANKRD37 mRNA	CTD	PMID:21396975
Ankrd37	Rat	indometacin	multiple interactions	ISO	RGD:1604164	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression more ...	CTD	PMID:28628672
Ankrd37	Rat	iron atom	increases expression	EXP		6480464	Iron deficiency results in increased expression of ANKRD37 mRNA	CTD	PMID:16629162
Ankrd37	Rat	iron atom	increases expression	ISO	RGD:1616237	6480464	Iron deficiency results in increased expression of ANKRD37 mRNA	CTD	PMID:23776592
Ankrd37	Rat	iron(0)	increases expression	ISO	RGD:1616237	6480464	Iron deficiency results in increased expression of ANKRD37 mRNA	CTD	PMID:23776592
Ankrd37	Rat	iron(0)	increases expression	EXP		6480464	Iron deficiency results in increased expression of ANKRD37 mRNA	CTD	PMID:16629162
Ankrd37	Rat	leflunomide	decreases expression	ISO	RGD:1604164	6480464	leflunomide results in decreased expression of ANKRD37 mRNA	CTD	PMID:28988120
Ankrd37	Rat	lipopolysaccharide	increases expression	ISO	RGD:1604164	6480464	Lipopolysaccharides results in increased expression of ANKRD37 mRNA	CTD	PMID:35811015
Ankrd37	Rat	lipopolysaccharide	multiple interactions	ISO	RGD:1604164	6480464	[S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of ANKRD37 mRNA; [S-(1,2-dichlorovinyl)cysteine more ...	CTD	PMID:35811015
Ankrd37	Rat	menadione	decreases expression	ISO	RGD:1616237	6480464	Vitamin K 3 results in decreased expression of ANKRD37 mRNA	CTD	PMID:25270620
Ankrd37	Rat	methimazole	decreases expression	EXP		6480464	Methimazole results in decreased expression of ANKRD37 mRNA	CTD	PMID:30047161
Ankrd37	Rat	methoxyacetic acid	decreases expression	EXP		6480464	methoxyacetic acid results in decreased expression of ANKRD37 mRNA	CTD	PMID:20864626
Ankrd37	Rat	methyl methanesulfonate	decreases expression	ISO	RGD:1604164	6480464	Methyl Methanesulfonate results in decreased expression of ANKRD37 mRNA	CTD	PMID:23649840
Ankrd37	Rat	methylmercury chloride	decreases expression	EXP		6480464	methylmercuric chloride results in decreased expression of ANKRD37 mRNA	CTD	PMID:20864626
Ankrd37	Rat	methylmercury chloride	decreases expression	ISO	RGD:1604164	6480464	methylmercuric chloride results in decreased expression of ANKRD37 mRNA	CTD	PMID:23179753\|PMID:27188386
Ankrd37	Rat	mithramycin	decreases expression	EXP		6480464	Plicamycin results in decreased expression of ANKRD37 mRNA	CTD	PMID:23814049
Ankrd37	Rat	mono(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1604164	6480464	mono-(2-ethylhexyl)phthalate results in decreased expression of ANKRD37 mRNA	CTD	PMID:36695872
Ankrd37	Rat	Monobutylphthalate	decreases expression	EXP		6480464	monobutyl phthalate results in decreased expression of ANKRD37 mRNA	CTD	PMID:20864626
Ankrd37	Rat	N-methyl-4-phenylpyridinium	decreases expression	EXP		6480464	1-Methyl-4-phenylpyridinium results in decreased expression of ANKRD37 mRNA	CTD	PMID:28801915
Ankrd37	Rat	N-methyl-4-phenylpyridinium	increases methylation	EXP		6480464	1-Methyl-4-phenylpyridinium results in increased methylation of ANKRD37 gene	CTD	PMID:28801915
Ankrd37	Rat	nickel dichloride	increases expression	ISO	RGD:1604164	6480464	nickel chloride results in increased expression of ANKRD37 mRNA	CTD	PMID:21455298
Ankrd37	Rat	nickel dichloride	affects expression	EXP		6480464	nickel chloride affects the expression of ANKRD37 mRNA	CTD	PMID:22110744
Ankrd37	Rat	nitrofen	increases expression	EXP		6480464	nitrofen results in increased expression of ANKRD37 mRNA	CTD	PMID:26720608
Ankrd37	Rat	ozone	multiple interactions	ISO	RGD:1616237	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ...	CTD	PMID:34911549
Ankrd37	Rat	p-chloromercuribenzoic acid	multiple interactions	ISO	RGD:1604164	6480464	[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Ankrd37	Rat	paracetamol	increases expression	ISO	RGD:1604164	6480464	Acetaminophen results in increased expression of ANKRD37 mRNA	CTD	PMID:21420995
Ankrd37	Rat	perfluorohexanesulfonic acid	increases expression	ISO	RGD:1616237	6480464	perfluorohexanesulfonic acid results in increased expression of ANKRD37 mRNA	CTD	PMID:37995155
Ankrd37	Rat	Pf-06840003	multiple interactions	ISO	RGD:1604164	6480464	PF-06840003 inhibits the reaction [APP protein mutant form results in decreased expression of ANKRD37 mRNA]	CTD	PMID:39172838
Ankrd37	Rat	pioglitazone	multiple interactions	ISO	RGD:1604164	6480464	[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANKRD37 mRNA; pioglitazone inhibits the reaction more ...	CTD	PMID:20847119
Ankrd37	Rat	pirinixic acid	multiple interactions	ISO	RGD:1616237	6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ...	CTD	PMID:19710929
Ankrd37	Rat	pirinixic acid	decreases expression	ISO	RGD:1616237	6480464	pirinixic acid results in decreased expression of ANKRD37 mRNA	CTD	PMID:23811191
Ankrd37	Rat	quercetin	decreases expression	ISO	RGD:1604164	6480464	Quercetin results in decreased expression of ANKRD37 mRNA	CTD	PMID:21632981
Ankrd37	Rat	quinolin-8-ol	decreases expression	ISO	RGD:1604164	6480464	Oxyquinoline results in decreased expression of ANKRD37 mRNA	CTD	PMID:21632981
Ankrd37	Rat	rac-lactic acid	decreases expression	ISO	RGD:1604164	6480464	Lactic Acid results in decreased expression of ANKRD37 mRNA	CTD	PMID:30851411
Ankrd37	Rat	resorcinol	increases expression	ISO	RGD:1604164	6480464	resorcinol results in increased expression of ANKRD37 mRNA	CTD	PMID:22623647
Ankrd37	Rat	rotenone	decreases expression	EXP		6480464	Rotenone results in decreased expression of ANKRD37 mRNA	CTD	PMID:19013527
Ankrd37	Rat	rotenone	increases expression	ISO	RGD:1604164	6480464	Rotenone results in increased expression of ANKRD37 mRNA	CTD	PMID:29955902
Ankrd37	Rat	S-(1,2-dichlorovinyl)-L-cysteine	decreases expression	ISO	RGD:1604164	6480464	S-(1,2-dichlorovinyl)cysteine results in decreased expression of ANKRD37 mRNA	CTD	PMID:33725128
Ankrd37	Rat	S-(1,2-dichlorovinyl)-L-cysteine	multiple interactions	ISO	RGD:1604164	6480464	[S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of ANKRD37 mRNA; [S-(1,2-dichlorovinyl)cysteine more ...	CTD	PMID:35811015
Ankrd37	Rat	S-nitrosoglutathione	increases expression	ISO	RGD:1604164	6480464	S-Nitrosoglutathione results in increased expression of ANKRD37 mRNA	CTD	PMID:38825487
Ankrd37	Rat	SB 431542	multiple interactions	ISO	RGD:1604164	6480464	[NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ...	CTD	PMID:27188386
Ankrd37	Rat	silicon dioxide	increases expression	ISO	RGD:1604164	6480464	Silicon Dioxide analog results in increased expression of ANKRD37 mRNA	CTD	PMID:25895662
Ankrd37	Rat	silver atom	increases expression	ISO	RGD:1604164	6480464	Silver results in increased expression of ANKRD37 mRNA	CTD	PMID:26014281
Ankrd37	Rat	silver(0)	increases expression	ISO	RGD:1604164	6480464	Silver results in increased expression of ANKRD37 mRNA	CTD	PMID:26014281
Ankrd37	Rat	sodium arsenate	multiple interactions	ISO	RGD:1604164	6480464	[sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ANKRD37 more ...	CTD	PMID:32525701
Ankrd37	Rat	sotorasib	multiple interactions	ISO	RGD:1604164	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANKRD37 mRNA	CTD	PMID:36139627
Ankrd37	Rat	succimer	multiple interactions	ISO	RGD:1616237	6480464	[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ANKRD37 mRNA	CTD	PMID:21641980
Ankrd37	Rat	sulfadimethoxine	decreases expression	EXP		6480464	Sulfadimethoxine results in decreased expression of ANKRD37 mRNA	CTD	PMID:30047161
Ankrd37	Rat	sunitinib	increases expression	ISO	RGD:1604164	6480464	Sunitinib results in increased expression of ANKRD37 mRNA	CTD	PMID:31533062
Ankrd37	Rat	tert-butyl hydroperoxide	multiple interactions	ISO	RGD:1604164	6480464	[Pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANKRD37 mRNA; [Rosiglitazone co-treated with tert-Butylhydroperoxide] more ...	CTD	PMID:20847119
Ankrd37	Rat	tert-butyl hydroperoxide	increases expression	ISO	RGD:1604164	6480464	tert-Butylhydroperoxide results in increased expression of ANKRD37 mRNA	CTD	PMID:20847119
Ankrd37	Rat	testosterone	increases expression	ISO	RGD:1604164	6480464	Testosterone results in increased expression of ANKRD37 mRNA	CTD	PMID:21592394
Ankrd37	Rat	testosterone	multiple interactions	ISO	RGD:1604164	6480464	[Testosterone co-treated with Calcitriol] results in increased expression of ANKRD37 mRNA	CTD	PMID:21592394
Ankrd37	Rat	thalidomide	decreases expression	ISO	RGD:1616237	6480464	Thalidomide results in decreased expression of ANKRD37 mRNA	CTD	PMID:26217789
Ankrd37	Rat	thimerosal	decreases expression	ISO	RGD:1604164	6480464	Thimerosal results in decreased expression of ANKRD37 mRNA	CTD	PMID:27188386
Ankrd37	Rat	titanium dioxide	increases expression	ISO	RGD:1616237	6480464	titanium dioxide results in increased expression of ANKRD37 mRNA	CTD	PMID:27760801
Ankrd37	Rat	titanium dioxide	increases methylation	ISO	RGD:1616237	6480464	titanium dioxide results in increased methylation of ANKRD37 promoter	CTD	PMID:35295148
Ankrd37	Rat	titanium dioxide	decreases methylation	ISO	RGD:1616237	6480464	titanium dioxide results in decreased methylation of ANKRD37 promoter	CTD	PMID:35295148
Ankrd37	Rat	trametinib	multiple interactions	ISO	RGD:1604164	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANKRD37 mRNA	CTD	PMID:36139627
Ankrd37	Rat	tributylstannane	increases expression	EXP		6480464	tributyltin results in increased expression of ANKRD37 mRNA	CTD	PMID:21683754
Ankrd37	Rat	triphenyl phosphate	affects expression	ISO	RGD:1604164	6480464	triphenyl phosphate affects the expression of ANKRD37 mRNA	CTD	PMID:37042841
Ankrd37	Rat	triptonide	increases expression	ISO	RGD:1616237	6480464	triptonide results in increased expression of ANKRD37 mRNA	CTD	PMID:33045310
Ankrd37	Rat	troglitazone	multiple interactions	ISO	RGD:1604164	6480464	[troglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANKRD37 mRNA; troglitazone inhibits the reaction more ...	CTD	PMID:20847119
Ankrd37	Rat	valproic acid	decreases expression	ISO	RGD:1604164	6480464	Valproic Acid results in decreased expression of ANKRD37 mRNA	CTD	PMID:23179753\|PMID:27188386
Ankrd37	Rat	valproic acid	increases expression	EXP		6480464	Valproic Acid results in increased expression of ANKRD37 mRNA	CTD	PMID:29427782
Ankrd37	Rat	valproic acid	increases expression	ISO	RGD:1604164	6480464	Valproic Acid results in increased expression of ANKRD37 mRNA	CTD	PMID:28001369
Ankrd37	Rat	vincristine	decreases expression	ISO	RGD:1604164	6480464	Vincristine results in decreased expression of ANKRD37 mRNA	CTD	PMID:23649840
Ankrd37	Rat	vorinostat	decreases expression	ISO	RGD:1604164	6480464	vorinostat results in decreased expression of ANKRD37 mRNA	CTD	PMID:27188386
Ankrd37	Rat	zinc atom	multiple interactions	ISO	RGD:1604164	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of ANKRD37 mRNA	CTD	PMID:18593933
Ankrd37	Rat	zinc dichloride	multiple interactions	ISO	RGD:1604164	6480464	zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKRD37 mRNA]	CTD	PMID:22202117
Ankrd37	Rat	zinc(0)	multiple interactions	ISO	RGD:1604164	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of ANKRD37 mRNA	CTD	PMID:18593933

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ankrd37	Rat	cytoplasm	is_active_in	IBA	MGI:3603344\|PANTHER:PTN002794086\|UniProtKB:Q7Z713	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ankrd37	Rat	cytoplasm	located_in	ISO	RGD:1616237	1624291	PMID:21723927	RGD	PMID:21723927
Ankrd37	Rat	cytosol	located_in	IEA	UniProtKB:Q7Z713\|ensembl:ENSP00000335147	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ankrd37	Rat	cytosol	located_in	ISO	RGD:1604164	1624291		RGD	GO_REF:0000052
Ankrd37	Rat	male germ cell nucleus	located_in	ISO	RGD:1616237	1624291	PMID:21723927	RGD	PMID:21723927
Ankrd37	Rat	mitochondrion	located_in	IEA	UniProtKB:Q7Z713\|ensembl:ENSP00000335147	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ankrd37	Rat	mitochondrion	located_in	ISO	RGD:1604164	1624291		RGD	GO_REF:0000052
Ankrd37	Rat	nucleoplasm	located_in	IEA	UniProtKB:Q7Z713\|ensembl:ENSP00000335147	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ankrd37	Rat	nucleoplasm	located_in	ISO	RGD:1604164	1624291		RGD	GO_REF:0000052

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ankrd37	Rat	protein binding	enables	ISO	RGD:1604164	1624291	UniProtKB:P36508\|UniProtKB:Q9NWT6 PMID:32296183	RGD	PMID:32296183
Ankrd37	Rat	protein binding	enables	ISO	RGD:1616237	1624291	PR:Q9Z2G0 PMID:21723927	RGD	PMID:21723927

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Beukes hip dysplasia (ISO)

Cerebral Visual Impairment and Intellectual Disability (ISO)

developmental dysplasia of the hip (ISO)

dilated cardiomyopathy (ISO)

Herpes Simplex Encephalitis 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,10-phenanthroline (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-diaminotoluene (ISO)

2-hydroxypropanoic acid (ISO)

2-palmitoylglycerol (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

amitrole (EXP)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (ISO)

caffeine (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

clothianidin (ISO)

cobalt dichloride (EXP,ISO)

cobalt(2+) sulfate (ISO)

copper atom (ISO)

copper(0) (ISO)

coumarin 460 (ISO)

crotonaldehyde (ISO)

curcumin (ISO)

cyclosporin A (ISO)

deoxynivalenol (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

diphenylcyclopropenone (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethyl methanesulfonate (ISO)

fluoranthene (ISO)

formaldehyde (ISO)

GSK-J4 (ISO)

indole-3-methanol (EXP)

indometacin (ISO)

iron atom (EXP,ISO)

iron(0) (EXP,ISO)

leflunomide (ISO)

lipopolysaccharide (ISO)

menadione (ISO)

methimazole (EXP)

methoxyacetic acid (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (EXP,ISO)

mithramycin (EXP)

mono(2-ethylhexyl) phthalate (ISO)

Monobutylphthalate (EXP)

N-methyl-4-phenylpyridinium (EXP)

nickel dichloride (EXP,ISO)

nitrofen (EXP)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

Pf-06840003 (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

quercetin (ISO)

quinolin-8-ol (ISO)

rac-lactic acid (ISO)

resorcinol (ISO)

rotenone (EXP,ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

S-nitrosoglutathione (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sotorasib (ISO)

succimer (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

thalidomide (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

trametinib (ISO)

tributylstannane (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

troglitazone (ISO)

valproic acid (EXP,ISO)

vincristine (ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc dichloride (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IBA,ISO)

cytosol (IEA,ISO)

male germ cell nucleus (ISO)

mitochondrion (IEA,ISO)

nucleoplasm (IEA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:21723927

Genomics

Comparative Map Data

Ankrd37
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	53,001,487 - 53,004,545 (+)	NCBI		GRCr8
mRatBN7.2	16	46,268,933 - 46,271,971 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	46,268,443 - 46,271,963 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	51,670,260 - 51,673,301 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	55,039,437 - 55,042,473 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	50,309,635 - 50,312,676 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	49,463,016 - 49,465,905 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	49,462,889 - 49,465,888 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	49,189,582 - 49,192,471 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	49,549,527 - 49,552,416 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	44,267,470 - 44,270,359 (+)	NCBI		Celera
Cytogenetic Map	16	q11	NCBI

ANKRD37
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	185,396,841 - 185,400,723 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	185,396,021 - 185,400,628 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	186,317,995 - 186,321,395 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	186,554,834 - 186,558,384 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	4	183,644,030 - 183,647,577 (+)	NCBI		Celera
Cytogenetic Map	4	q35.1	NCBI
HuRef	4	182,071,296 - 182,074,843 (+)	NCBI		HuRef
CHM1_1	4	186,294,269 - 186,297,819 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	188,740,172 - 188,743,575 (+)	NCBI		T2T-CHM13v2.0

Ankrd37
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	46,449,945 - 46,452,904 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	46,449,939 - 46,458,744 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	45,996,908 - 46,000,414 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	45,996,902 - 46,005,707 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	47,082,262 - 47,085,204 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	47,495,725 - 47,498,667 (-)	NCBI		MGSCv36	mm8
Celera	8	48,679,833 - 48,682,775 (-)	NCBI		Celera
Cytogenetic Map	8	B1.1	NCBI
cM Map	8	25.99	NCBI

Ankrd37
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	23,655,716 - 23,658,009 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	23,655,501 - 23,658,069 (-)	NCBI	ChiLan1.0	ChiLan1.0

ANKRD37
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	183,129,080 - 183,135,779 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	183,479,314 - 183,486,872 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	177,559,012 - 177,563,343 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	189,776,194 - 189,779,945 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	189,776,184 - 189,780,053 (+)	Ensembl	panpan1.1		panPan2

ANKRD37
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	45,230,095 - 45,233,411 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	45,230,096 - 45,233,418 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	45,717,733 - 45,721,065 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	47,446,145 - 47,449,515 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	16	45,413,967 - 45,417,336 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	46,026,797 - 46,030,138 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	46,158,191 - 46,161,564 (-)	NCBI		UU_Cfam_GSD_1.0

Ankrd37
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	34,161,993 - 34,164,625 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936554	3,944,205 - 3,948,450 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936554	3,945,343 - 3,948,155 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANKRD37
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	46,445,881 - 46,450,097 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	46,445,789 - 46,450,046 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	53,346,602 - 53,349,746 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ANKRD37
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	131,348,511 - 131,352,071 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	131,347,975 - 131,353,985 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	111,608,196 - 111,613,847 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ankrd37
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624769	16,251,596 - 16,253,467 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624769	16,251,387 - 16,254,298 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ankrd37
9 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	196
Count of miRNA genes:	160
Interacting mature miRNAs:	167
Transcripts:	ENSRNOT00000039909
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	44455123	89455123	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	36928782	81928782	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	41992064	86992064	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
2302057	Pia29	Pristane induced arthritis QTL 29	3.6	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	16	28468701	73468701	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	49099196	91442908	Rat
1357403	Slep4	Serum leptin concentration QTL 4	3.91		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	32361043	77361043	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4234212	53708481	Rat
631833	Sach2	Saccharin preference QTL 2	4	0.01	consumption behavior trait (VT:0002069)	calculated saccharin drink intake rate (CMO:0001613)	16	49757666	56898388	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	31058039	76058039	Rat
1298529	Arunc1	Aerobic running capacity QTL 1	4		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	34398294	79398294	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	31885271	76885271	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	44455123	89455123	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17730818	72536785	Rat
2301406	Kidm39	Kidney mass QTL 39		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	16	15905802	60905802	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat

Markers in Region

RH131258

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	16	53,003,692 - 53,004,358 (+)	Marker Load Pipeline
mRatBN7.2	16	46,271,118 - 46,271,784 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	49,465,061 - 49,465,726	NCBI	Rnor6.0
Rnor_5.0	16	49,191,627 - 49,192,292	UniSTS	Rnor5.0
RGSC_v3.4	16	49,551,572 - 49,552,237	UniSTS	RGSC3.4
Celera	16	44,269,515 - 44,270,180	UniSTS
Cytogenetic Map	16	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275516	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC130162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000039909 ⟹ ENSRNOP00000049105

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	46,268,443 - 46,271,963 (+)	Ensembl
Rnor_6.0 Ensembl	16	49,462,889 - 49,465,888 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000120066 ⟹ ENSRNOP00000088167

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	46,269,074 - 46,271,577 (+)	Ensembl

RefSeq Acc Id:

NM_001108400 ⟹ NP_001101870

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	53,001,507 - 53,004,545 (+)	NCBI
mRatBN7.2	16	46,268,933 - 46,271,971 (+)	NCBI
Rnor_6.0	16	49,463,016 - 49,465,905 (+)	NCBI
Rnor_5.0	16	49,189,582 - 49,192,471 (+)	NCBI
RGSC_v3.4	16	49,549,527 - 49,552,416 (+)	RGD
Celera	16	44,267,470 - 44,270,359 (+)	RGD

Sequence:

show sequence

GCACTCTTACCGACCGGTTTCGCCTCGCTGAACTCCCGGAGACACTTGTCATCTGCTTTAGGGG
GCGATGCTGTTGCTTAGCTGCAACTTGGAGGAGGATGGCCTTAAGAATTTGCTGGAGACAGGAG
CATCAGTCAACGCACCCCCGGATCCTCAAGAGCAGTCGCCTGTTCACCTAGCTGCAGGTGGCGG
CCTTGCTTGCTTTCTTCTCTGGCAGCTGCAAACCGGTGCTGACCTCAACCAACAGGATGTGTTG
GGAGAAACTCCACTCCACAAGGCAGCCAAAGTTGGAAGCCTAGAGTGCCTTAGCCTCCTGGTGG
CCAGTGATGTCCGGATTGACTTATGTAATAAAAATGGGCAAACAGCTGAAGATCTTGCTTGGTC
ATGTGGCTTTCCAGAATGTGCCAGGTTTCTAACAATGATTAAATGTACGCAGACAGCAAAATCC
TCACGTGAGCACCCTGAGGGTGACCCCTATGCTCCTGTGCTGAGACAGAAGCGGAGTTTCAGAA
CTATGGAGAGCAGAGTGTTGAAGAGAAAGTGTTGATGATGTCTTGTTGGGCAAGAGGAGAGAAG
AGGCTTGAAGACGGGCTTCACTTCAGACAGATCTATAAGCCATTGCTTTGGCTTAACACATGGC
TACACTCCTGAGGAGGAAAGCTTTCTTCCAAGTGAAGAGAAATTCATTCATGCATGTGTTTACA
TGACTAGTATTTTGGATGTACATGTTTTGTTATTTAACTTATTAAAAGAATATTCAAGCAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039094639 ⟹ XP_038950567

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	53,001,492 - 53,003,673 (+)	NCBI
mRatBN7.2	16	46,269,025 - 46,271,203 (+)	NCBI

RefSeq Acc Id:

XM_063275515 ⟹ XP_063131585

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	53,001,487 - 53,004,545 (+)	NCBI

RefSeq Acc Id:

XM_063275516 ⟹ XP_063131586

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	53,001,974 - 53,004,545 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101870	(Get FASTA)	NCBI Sequence Viewer
	XP_038950567	(Get FASTA)	NCBI Sequence Viewer
	XP_063131585	(Get FASTA)	NCBI Sequence Viewer
	XP_063131586	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66884	(Get FASTA)	NCBI Sequence Viewer
	EDL78869	(Get FASTA)	NCBI Sequence Viewer
	EDL78870	(Get FASTA)	NCBI Sequence Viewer
	EDL78871	(Get FASTA)	NCBI Sequence Viewer
	EDL78872	(Get FASTA)	NCBI Sequence Viewer
	EDL78873	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000049105.4
	ENSRNOP00000088167
	ENSRNOP00000088167.1

RefSeq Acc Id:	NP_001101870 ⟸ NM_001108400
- UniProtKB:	B2RYS4 (UniProtKB/TrEMBL), F7EMG3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLLSCNLEEDGLKNLLETGASVNAPPDPQEQSPVHLAAGGGLACFLLWQLQTGADLNQQDVLG ETPLHKAAKVGSLECLSLLVASDVRIDLCNKNGQTAEDLAWSCGFPECARFLTMIKCTQTAKSS REHPEGDPYAPVLRQKRSFRTMESRVLKRKC hide sequence

Ensembl Acc Id:

ENSRNOP00000049105 ⟸ ENSRNOT00000039909

RefSeq Acc Id:	XP_038950567 ⟸ XM_039094639
- Peptide Label:	isoform X2
- UniProtKB:	A6JPQ1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000088167 ⟸ ENSRNOT00000120066

RefSeq Acc Id:	XP_063131585 ⟸ XM_063275515
- Peptide Label:	isoform X1
- UniProtKB:	F7EMG3 (UniProtKB/TrEMBL), A0A8I6A8T4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063131586 ⟸ XM_063275516
- Peptide Label:	isoform X3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B2RYS4-F1-model_v2	AlphaFold	B2RYS4	1-159	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700103

Promoter ID:

EPDNEW_R10626

Type:

single initiation site

Name:

Ankrd37_1

Description:

ankyrin repeat domain 37

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	49,463,014 - 49,463,074	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565715	AgrOrtholog
BioCyc Gene	G2FUF-11332	BioCyc
Ensembl Genes	ENSRNOG00000031335	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000039909.5	UniProtKB/TrEMBL
	ENSRNOT00000120066	ENTREZGENE
	ENSRNOT00000120066.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.20	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:6887335	IMAGE-MGC_LOAD
InterPro	Ank_Repeat/CDKN_Inhibitor	UniProtKB/TrEMBL
	Ankyrin_rpt	UniProtKB/TrEMBL
	Ankyrin_rpt-contain_sf	UniProtKB/TrEMBL
KEGG Report	rno:361149	UniProtKB/TrEMBL
MGC_CLONE	MGC:188821	IMAGE-MGC_LOAD
NCBI Gene	361149	ENTREZGENE
PANTHER	ANK_REP_REGION DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 37	UniProtKB/TrEMBL
Pfam	Ank_2	UniProtKB/TrEMBL
PhenoGen	Ankrd37	PhenoGen
PROSITE	ANK_REP_REGION	UniProtKB/TrEMBL
	ANK_REPEAT	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000031335	RatGTEx
SMART	ANK	UniProtKB/TrEMBL
Superfamily-SCOP	ANK	UniProtKB/TrEMBL
UniProt	A0A8I6A8T4	ENTREZGENE, UniProtKB/TrEMBL
	A6JPQ1	ENTREZGENE, UniProtKB/TrEMBL
	B2RYS4	ENTREZGENE, UniProtKB/TrEMBL
	F7EMG3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Ankrd37	ankyrin repeat domain 37	RGD1565715_predicted	similar to low density lipoprotein receptor-related protein binding protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1565715_predicted	similar to low density lipoprotein receptor-related protein binding protein (predicted)	LOC361149	similar to low density lipoprotein receptor-related protein binding protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC361149	similar to low density lipoprotein receptor-related protein binding protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar