(20S)-ginsenoside Rg3 decreases expression ISO SOX2 (Homo sapiens) 6480464 ginsenoside Rg3 results in decreased expression of SOX2 mRNA CTD PMID:31916386 (R)-pantothenic acid decreases expression ISO SOX2 (Homo sapiens) 6480464 Pantothenic Acid results in decreased expression of SOX2 mRNA CTD PMID:19397697 (S)-naringenin decreases expression ISO SOX2 (Homo sapiens) 6480464 naringenin results in decreased expression of SOX2 protein CTD PMID:27468969 1,2-dichloroethane decreases expression ISO Sox2 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of SOX2 mRNA CTD PMID:28960355 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of SOX2 mRNA CTD PMID:30387366 17beta-estradiol decreases expression ISO SOX2 (Homo sapiens) 6480464 Estradiol results in decreased expression of SOX2 mRNA CTD PMID:16474171 more ... 17beta-estradiol increases activity ISO SOX2 (Homo sapiens) 6480464 Estradiol results in increased activity of SOX2 protein CTD PMID:27592001 17beta-estradiol increases expression ISO SOX2 (Homo sapiens) 6480464 Estradiol results in increased expression of SOX2 mRNA CTD PMID:24424067 17beta-estradiol multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Arsenic co-treated with Estradiol] results in decreased expression of SOX2 mRNA and [Estradiol binds to ESR2 protein] which results in increased expression of SOX2 mRNA CTD PMID:20404318 and PMID:33047385 17beta-estradiol 3-benzoate decreases methylation EXP 6480464 estradiol 3-benzoate results in decreased methylation of SOX2 promoter CTD PMID:27415467 17beta-estradiol 3-benzoate increases expression EXP 6480464 estradiol 3-benzoate results in increased expression of SOX2 mRNA CTD PMID:27415467 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:27291303 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Sox2 (Mus musculus) 6480464 2 more ... CTD PMID:34547414 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO SOX2 (Homo sapiens) 6480464 2 more ... CTD PMID:31326446 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Sox2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of SOX2 mRNA and Tetrachlorodibenzodioxin affects the expression of SOX2 protein CTD PMID:21570461 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO SOX2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of SOX2 mRNA CTD PMID:30203000 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO SOX2 (Homo sapiens) 6480464 N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SOX2 mRNA] CTD PMID:30203000 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Verapamil co-treated with kaempferol] results in decreased expression of SOX2 mRNA CTD PMID:35063459 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [INS co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA CTD PMID:21350315 3-methyladenine increases expression ISO Sox2 (Mus musculus) 6480464 3-methyladenine results in increased expression of SOX2 mRNA CTD PMID:21681844 4,4'-sulfonyldiphenol increases expression ISO SOX2 (Homo sapiens) 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of SOX2 mRNA CTD PMID:36565802 5-aza-2'-deoxycytidine decreases expression ISO Sox2 (Mus musculus) 6480464 Decitabine results in decreased expression of SOX2 mRNA CTD PMID:27915011 5-azacytidine increases expression EXP 6480464 Azacitidine results in increased expression of SOX2 mRNA CTD PMID:27415467 5-fluorouracil decreases expression ISO Sox2 (Mus musculus) 6480464 Fluorouracil results in decreased expression of SOX2 protein CTD PMID:21296659 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SOX2 mRNA CTD PMID:30047161 9-cis-retinoic acid decreases expression ISO SOX2 (Homo sapiens) 6480464 Alitretinoin results in decreased expression of SOX2 mRNA CTD PMID:36805303 acrylamide decreases expression ISO SOX2 (Homo sapiens) 6480464 Acrylamide results in decreased expression of SOX2 mRNA and Acrylamide results in decreased expression of SOX2 protein CTD PMID:32763439 aflatoxin B1 decreases methylation ISO SOX2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of SOX2 gene CTD PMID:27153756 aflatoxin M1 decreases expression ISO SOX2 (Homo sapiens) 6480464 Aflatoxin M1 results in decreased expression of SOX2 mRNA CTD PMID:30928695 aldehydo-D-glucose decreases expression ISO SOX2 (Homo sapiens) 6480464 Glucose results in decreased expression of SOX2 protein CTD PMID:33992720 all-trans-retinoic acid multiple interactions ISO Sox2 (Mus musculus) 6480464 NR6A1 protein affects the reaction [Tretinoin results in decreased expression of SOX2 mRNA] and Tretinoin results in decreased expression of and results in increased degradation of SOX2 protein CTD PMID:16166633 and PMID:30442713 all-trans-retinoic acid multiple interactions ISO SOX2 (Homo sapiens) 6480464 [4-(5-benzo(1 more ... CTD PMID:30093655 and PMID:31711903 all-trans-retinoic acid affects expression ISO SOX2 (Homo sapiens) 6480464 Tretinoin affects the expression of SOX2 mRNA CTD PMID:31600526 all-trans-retinoic acid increases degradation ISO Sox2 (Mus musculus) 6480464 Tretinoin results in increased degradation of SOX2 protein modified form CTD PMID:30442713 all-trans-retinoic acid decreases expression ISO SOX2 (Homo sapiens) 6480464 Tretinoin results in decreased expression of SOX2 mRNA CTD PMID:21934132 more ... anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO SOX2 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of SOX2 protein] CTD PMID:23219847 antirheumatic drug increases expression ISO SOX2 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of SOX2 mRNA CTD PMID:24449571 apigenin decreases expression ISO SOX2 (Homo sapiens) 6480464 Apigenin results in decreased expression of SOX2 protein CTD PMID:27468969 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of SOX2 mRNA CTD PMID:34858468 arotinoid acid multiple interactions ISO SOX2 (Homo sapiens) 6480464 [4-(2-(5 more ... CTD PMID:34480604 arsane increases expression ISO Sox2 (Mus musculus) 6480464 Arsenic results in increased expression of SOX2 mRNA and Arsenic results in increased expression of SOX2 protein CTD PMID:23221970 and PMID:33124703 arsane multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Arsenic co-treated with Estradiol] results in decreased expression of SOX2 mRNA and [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SOX2 mRNA CTD PMID:32525701 and PMID:33047385 arsane increases expression ISO SOX2 (Homo sapiens) 6480464 Arsenic results in increased expression of SOX2 mRNA CTD PMID:29396848 arsenic atom increases expression ISO Sox2 (Mus musculus) 6480464 Arsenic results in increased expression of SOX2 mRNA and Arsenic results in increased expression of SOX2 protein CTD PMID:23221970 and PMID:33124703 arsenic atom multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Arsenic co-treated with Estradiol] results in decreased expression of SOX2 mRNA and [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SOX2 mRNA CTD PMID:32525701 and PMID:33047385 arsenic atom increases expression ISO SOX2 (Homo sapiens) 6480464 Arsenic results in increased expression of SOX2 mRNA CTD PMID:29396848 arsenite(3-) decreases expression ISO SOX2 (Homo sapiens) 6480464 arsenite results in decreased expression of SOX2 mRNA CTD PMID:23974009 arsenous acid multiple interactions ISO SOX2 (Homo sapiens) 6480464 4-(4-cyano-2-(2-(4-fluoronaphthalen-1-yl)propionylamino)phenyl)butyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein] more ... CTD PMID:29396848 more ... arsenous acid decreases expression ISO SOX2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of SOX2 mRNA CTD PMID:24685274 and PMID:33634982 arsenous acid decreases response to substance ISO SOX2 (Homo sapiens) 6480464 SOX2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:21703238 arsenous acid increases expression ISO SOX2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of SOX2 mRNA and Arsenic Trioxide results in increased expression of SOX2 protein CTD PMID:29396848 and PMID:29486283 aspartame affects localization ISO SOX2 (Homo sapiens) 6480464 Aspartame affects the localization of SOX2 protein CTD PMID:33992720 benzo[a]pyrene decreases expression ISO Sox2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of SOX2 mRNA CTD PMID:22228805 and PMID:27195522 benzo[a]pyrene decreases expression ISO SOX2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of SOX2 mRNA and Benzo(a)pyrene results in decreased expression of SOX2 protein CTD PMID:30659931 bis(2-ethylhexyl) phthalate decreases expression ISO SOX2 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of SOX2 mRNA CTD PMID:31163220 bisphenol A decreases expression ISO SOX2 (Homo sapiens) 6480464 bisphenol A results in decreased expression of SOX2 mRNA CTD PMID:16474171 and PMID:25051057 bisphenol A decreases expression ISO Sox2 (Mus musculus) 6480464 bisphenol A results in decreased expression of SOX2 mRNA CTD PMID:35219798 bisphenol A multiple interactions ISO SOX2 (Homo sapiens) 6480464 bisphenol A promotes the reaction [CREB1 protein modified form binds to SOX2 enhancer] CTD PMID:28244015 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SOX2 mRNA CTD PMID:27415467 and PMID:30387366 bisphenol A affects methylation ISO Sox2 (Mus musculus) 6480464 bisphenol A affects the methylation of SOX2 promoter CTD PMID:27334623 bisphenol A increases expression ISO SOX2 (Homo sapiens) 6480464 bisphenol A results in increased expression of SOX2 mRNA and bisphenol A results in increased expression of SOX2 protein CTD PMID:28244015 and PMID:35069845 bisphenol A affects methylation EXP 6480464 bisphenol A affects the methylation of SOX2 promoter CTD PMID:27415467 bisphenol A decreases methylation EXP 6480464 bisphenol A results in decreased methylation of SOX2 promoter CTD PMID:28728135 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SOX2 mRNA CTD PMID:25181051 and PMID:29097150 bisphenol A increases expression ISO Sox2 (Mus musculus) 6480464 bisphenol A results in increased expression of SOX2 mRNA and bisphenol A results in increased expression of SOX2 protein CTD PMID:23719110 more ... bromochloroacetic acid affects expression ISO Sox2 (Mus musculus) 6480464 bromochloroacetic acid affects the expression of SOX2 protein CTD PMID:21296659 buta-1,3-diene decreases expression ISO Sox2 (Mus musculus) 6480464 1 and 3-butadiene results in decreased expression of SOX2 mRNA CTD PMID:29038090 butanal decreases expression ISO SOX2 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of SOX2 mRNA CTD PMID:26079696 cadmium dichloride affects expression ISO Sox2 (Mus musculus) 6480464 Cadmium Chloride affects the expression of SOX2 mRNA CTD PMID:18974090 cadmium sulfate increases expression ISO Sox2 (Mus musculus) 6480464 cadmium sulfate results in increased expression of SOX2 mRNA CTD PMID:19274763 carbofuran decreases expression EXP 6480464 Carbofuran results in decreased expression of SOX2 protein CTD PMID:22240977 carbon atom multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Carbon] which results in decreased expression of SOX2 mRNA CTD PMID:31791492 carbon nanotube decreases expression ISO Sox2 (Mus musculus) 6480464 Nanotubes and Carbon analog results in decreased expression of SOX2 mRNA CTD PMID:25554681 carboplatin increases expression ISO SOX2 (Homo sapiens) 6480464 Carboplatin results in increased expression of SOX2 mRNA CTD PMID:25605917 carvedilol increases expression EXP 6480464 carvedilol results in increased expression of SOX2 mRNA CTD PMID:27288437 carvedilol increases expression ISO Sox2 (Mus musculus) 6480464 carvedilol results in increased expression of SOX2 mRNA CTD PMID:27288437 celecoxib multiple interactions ISO SOX2 (Homo sapiens) 6480464 Celecoxib inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein] and Dinoprostone inhibits the reaction [Celecoxib inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]] CTD PMID:29396848 CGP 52608 multiple interactions ISO SOX2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to SOX2 gene] CTD PMID:28238834 CHIR 99021 decreases expression ISO SOX2 (Homo sapiens) 6480464 Chir 99021 results in decreased expression of SOX2 mRNA CTD PMID:31711903 CHIR 99021 multiple interactions ISO SOX2 (Homo sapiens) 6480464 [4-(2-(5 more ... CTD PMID:31711903 and PMID:34480604 chlordecone increases expression ISO Sox2 (Mus musculus) 6480464 Chlordecone results in increased expression of SOX2 mRNA CTD PMID:33711761 chloroprene increases expression ISO Sox2 (Mus musculus) 6480464 Chloroprene results in increased expression of SOX2 mRNA CTD PMID:23125180 chlorpromazine decreases expression ISO SOX2 (Homo sapiens) 6480464 Chlorpromazine results in decreased expression of SOX2 mRNA CTD PMID:30703373 chromium(6+) multiple interactions ISO Sox2 (Mus musculus) 6480464 MAP2K7 protein promotes the reaction [chromium hexavalent ion results in increased expression of SOX2 mRNA] CTD PMID:19654923 chromium(6+) increases expression ISO Sox2 (Mus musculus) 6480464 chromium hexavalent ion results in increased expression of SOX2 mRNA CTD PMID:19654923 chrysene increases expression ISO Sox2 (Mus musculus) 6480464 chrysene results in increased expression of SOX2 mRNA CTD PMID:26377693 ciprofloxacin decreases expression ISO SOX2 (Homo sapiens) 6480464 Ciprofloxacin results in decreased expression of SOX2 protein CTD PMID:26947806 cisplatin multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of SOX2 mRNA more ... CTD PMID:20705681 more ... Citreoviridin increases expression ISO Sox2 (Mus musculus) 6480464 citreoviridin results in increased expression of SOX2 mRNA CTD PMID:30071239 cobalt atom multiple interactions ISO SOX2 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which results in decreased expression of SOX2 mRNA CTD PMID:20105288 cobalt dichloride multiple interactions ISO SOX2 (Homo sapiens) 6480464 [EPAS1 protein results in increased susceptibility to cobaltous chloride] which results in increased expression of SOX2 mRNA more ... CTD PMID:24842335 and PMID:25805230 cobalt dichloride decreases expression ISO SOX2 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of SOX2 mRNA CTD PMID:20105288 cobalt dichloride increases expression ISO SOX2 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of SOX2 protein CTD PMID:24842335 colforsin daropate hydrochloride decreases expression ISO SOX2 (Homo sapiens) 6480464 Colforsin results in decreased expression of SOX2 protein CTD PMID:34897981 cortisol multiple interactions ISO SOX2 (Homo sapiens) 6480464 [4-(2-(5 more ... CTD PMID:34480604 crystal violet multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Gentian Violet results in decreased phosphorylation of and affects the localization of STAT3 protein] inhibits the reaction [STAT3 protein binds to SOX2 promoter] CTD PMID:27373978 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of SOX2 mRNA CTD PMID:27523638 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of SOX2 mRNA CTD PMID:26577399 curcumin increases expression ISO Sox2 (Mus musculus) 6480464 Curcumin results in increased expression of SOX2 mRNA and Curcumin results in increased expression of SOX2 protein CTD PMID:25822711 D-glucose decreases expression ISO SOX2 (Homo sapiens) 6480464 Glucose results in decreased expression of SOX2 protein CTD PMID:33992720 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of SOX2 mRNA CTD PMID:23640034 decabromodiphenyl ether decreases expression ISO SOX2 (Homo sapiens) 6480464 decabromobiphenyl ether results in decreased expression of SOX2 mRNA CTD PMID:26206603 decabromodiphenyl ether increases expression ISO SOX2 (Homo sapiens) 6480464 decabromobiphenyl ether results in increased expression of SOX2 mRNA CTD PMID:31326446 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of SOX2 mRNA CTD PMID:23640034 deoxycholic acid increases expression ISO Sox2 (Mus musculus) 6480464 Deoxycholic Acid results in increased expression of SOX2 mRNA CTD PMID:27151938 dexamethasone multiple interactions EXP 6480464 [INS co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA and MIR134 mRNA affects the reaction [Dexamethasone results in decreased expression of SOX2 mRNA] CTD PMID:21350315 and PMID:33619658 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of SOX2 mRNA and Dexamethasone results in decreased expression of SOX2 protein CTD PMID:33619658 dexamethasone multiple interactions ISO Sox2 (Mus musculus) 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA CTD PMID:28189605 diarsenic trioxide increases expression ISO SOX2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of SOX2 mRNA and Arsenic Trioxide results in increased expression of SOX2 protein CTD PMID:29396848 and PMID:29486283 diarsenic trioxide multiple interactions ISO SOX2 (Homo sapiens) 6480464 4-(4-cyano-2-(2-(4-fluoronaphthalen-1-yl)propionylamino)phenyl)butyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein] more ... CTD PMID:29396848 more ... diarsenic trioxide decreases expression ISO SOX2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of SOX2 mRNA CTD PMID:24685274 and PMID:33634982 diarsenic trioxide decreases response to substance ISO SOX2 (Homo sapiens) 6480464 SOX2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:21703238 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of SOX2 mRNA CTD PMID:17005392 dioxygen increases expression ISO SOX2 (Homo sapiens) 6480464 [Oxygen deficiency results in increased expression of CA9 mRNA] which results in increased expression of SOX2 mRNA CTD PMID:26305601 dorsomorphin multiple interactions ISO SOX2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 eckol decreases expression ISO SOX2 (Homo sapiens) 6480464 eckol results in decreased expression of SOX2 protein CTD PMID:21514314 elemental carbon multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Carbon] which results in decreased expression of SOX2 mRNA CTD PMID:31791492 ethanol increases expression EXP 6480464 Ethanol results in increased expression of SOX2 mRNA and Ethanol results in increased expression of SOX2 protein CTD PMID:29769550 etodolac multiple interactions ISO SOX2 (Homo sapiens) 6480464 Etodolac inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein] CTD PMID:29396848 etoposide multiple interactions ISO SOX2 (Homo sapiens) 6480464 FTL protein affects the reaction [Etoposide results in increased expression of SOX2 protein] CTD PMID:33969609 fluoxetine affects expression ISO Sox2 (Mus musculus) 6480464 Fluoxetine affects the expression of SOX2 mRNA CTD PMID:29893963 flurbiprofen increases expression ISO Sox2 (Mus musculus) 6480464 Flurbiprofen results in increased expression of SOX2 mRNA CTD PMID:16949054 folic acid decreases expression ISO Sox2 (Mus musculus) 6480464 Folic Acid results in decreased expression of SOX2 mRNA CTD PMID:25629700 fonofos increases methylation ISO SOX2 (Homo sapiens) 6480464 Fonofos results in increased methylation of SOX2 promoter CTD PMID:22847954 formaldehyde decreases expression ISO SOX2 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of SOX2 mRNA CTD PMID:20655997 gemcitabine increases expression ISO SOX2 (Homo sapiens) 6480464 Gemcitabine results in increased expression of SOX2 mRNA CTD PMID:25605917 genistein decreases expression ISO SOX2 (Homo sapiens) 6480464 Genistein results in decreased expression of SOX2 mRNA CTD PMID:16474171 glucose decreases expression ISO SOX2 (Homo sapiens) 6480464 Glucose results in decreased expression of SOX2 protein CTD PMID:33992720 glycerol 2-phosphate multiple interactions ISO Sox2 (Mus musculus) 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA CTD PMID:28189605 GS-441524 increases expression ISO Sox2 (Mus musculus) 6480464 GS-441524 results in increased expression of SOX2 mRNA CTD PMID:35605700 hexachlorophene decreases expression ISO Sox2 (Mus musculus) 6480464 Hexachlorophene results in decreased expression of SOX2 mRNA and Hexachlorophene results in decreased expression of SOX2 protein CTD PMID:25943520 hydroquinone decreases expression ISO SOX2 (Homo sapiens) 6480464 hydroquinone results in decreased expression of SOX2 mRNA CTD PMID:31256213 Indeno[1,2,3-cd]pyrene increases expression ISO SOX2 (Homo sapiens) 6480464 indeno(1 more ... CTD PMID:35687267 isoorientin decreases expression ISO SOX2 (Homo sapiens) 6480464 homoorientin results in decreased expression of SOX2 protein CTD PMID:34019859 ivermectin decreases expression ISO SOX2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of SOX2 mRNA and Ivermectin results in decreased expression of SOX2 protein CTD PMID:29257278 kaempferol decreases expression ISO SOX2 (Homo sapiens) 6480464 kaempferol results in decreased expression of SOX2 mRNA CTD PMID:35063459 kaempferol multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Verapamil co-treated with kaempferol] results in decreased expression of SOX2 mRNA CTD PMID:35063459 L-ascorbic acid increases expression ISO SOX2 (Homo sapiens) 6480464 Ascorbic Acid results in increased expression of SOX2 mRNA CTD PMID:21166886 L-ascorbic acid multiple interactions ISO SOX2 (Homo sapiens) 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA CTD PMID:34480604 L-ascorbic acid multiple interactions ISO Sox2 (Mus musculus) 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA CTD PMID:28189605 L-ascorbic acid 2-phosphate multiple interactions ISO SOX2 (Homo sapiens) 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA CTD PMID:34480604 lapatinib multiple interactions ISO SOX2 (Homo sapiens) 6480464 [lapatinib results in decreased susceptibility to lapatinib] which results in increased expression of SOX2 protein CTD PMID:26643609 lead diacetate increases expression ISO Sox2 (Mus musculus) 6480464 lead acetate results in increased expression of SOX2 mRNA CTD PMID:31715224 lupeol decreases expression ISO Sox2 (Mus musculus) 6480464 lupeol results in decreased expression of SOX2 protein CTD PMID:20979057 LY294002 multiple interactions ISO Sox2 (Mus musculus) 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with sodium arsenite] results in decreased expression of SOX2 protein CTD PMID:23143138 LY294002 decreases expression ISO Sox2 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of SOX2 protein CTD PMID:23143138 mercury dibromide decreases expression ISO SOX2 (Homo sapiens) 6480464 mercuric bromide results in decreased expression of SOX2 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO SOX2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of SOX2 mRNA CTD PMID:30047161 methylmercury chloride decreases expression ISO SOX2 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of SOX2 mRNA CTD PMID:28001369 methylmercury chloride increases expression ISO SOX2 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of SOX2 mRNA and methylmercuric chloride results in increased expression of SOX2 protein CTD PMID:34328791 methylparaben increases expression ISO SOX2 (Homo sapiens) 6480464 methylparaben results in increased expression of SOX2 mRNA CTD PMID:27581495 miconazole increases expression ISO Sox2 (Mus musculus) 6480464 Miconazole results in increased expression of SOX2 mRNA CTD PMID:27462272 naphthalene increases expression ISO Sox2 (Mus musculus) 6480464 naphthalene results in increased expression of SOX2 protein CTD PMID:16239640 nickel dichloride increases expression ISO SOX2 (Homo sapiens) 6480464 nickel chloride results in increased expression of SOX2 protein CTD PMID:26962057 Nonylphenol increases expression ISO Sox2 (Mus musculus) 6480464 nonylphenol results in increased expression of SOX2 mRNA CTD PMID:31288075 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of SOX2 mRNA CTD PMID:21703336 ochratoxin A multiple interactions EXP 6480464 SHH protein modified form inhibits the reaction [ochratoxin A results in decreased expression of SOX2 mRNA] CTD PMID:21703336 ozone multiple interactions ISO Sox2 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SOX2 mRNA CTD PMID:34911549 p-chloromercuribenzoic acid decreases expression ISO SOX2 (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in decreased expression of SOX2 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO SOX2 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 paclitaxel multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of SOX2 mRNA CTD PMID:20705681 panobinostat multiple interactions ISO SOX2 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 panobinostat decreases expression ISO SOX2 (Homo sapiens) 6480464 panobinostat results in decreased expression of SOX2 mRNA CTD PMID:26272509 paracetamol increases expression ISO SOX2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of SOX2 mRNA CTD PMID:26690555 paraquat decreases expression ISO Sox2 (Mus musculus) 6480464 Paraquat results in decreased expression of SOX2 mRNA CTD PMID:21463325 parathion increases methylation ISO SOX2 (Homo sapiens) 6480464 Parathion results in increased methylation of SOX2 promoter CTD PMID:22847954 perfluorooctane-1-sulfonic acid decreases expression ISO Sox2 (Mus musculus) 6480464 perfluorooctane sulfonic acid results in decreased expression of SOX2 mRNA and perfluorooctane sulfonic acid results in decreased expression of SOX2 protein CTD PMID:24098361 perfluorooctane-1-sulfonic acid increases expression ISO Sox2 (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased expression of SOX2 mRNA and perfluorooctane sulfonic acid results in increased expression of SOX2 protein CTD PMID:25510869 phenylephrine multiple interactions EXP 6480464 Phenylephrine inhibits the reaction [Iodine-131 inhibits the reaction [PAFAH1B1 protein binds to SOX2 protein]] CTD PMID:32278511 phenylmercury acetate decreases expression ISO SOX2 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of SOX2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO SOX2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 poly(I:C) increases expression ISO SOX2 (Homo sapiens) 6480464 Poly I-C results in increased expression of SOX2 protein CTD PMID:29486283 poly(I:C) multiple interactions ISO SOX2 (Homo sapiens) 6480464 Poly I-C promotes the reaction [MSI1 protein results in increased expression of SOX2 protein] CTD PMID:29486283 prostaglandin E2 multiple interactions ISO SOX2 (Homo sapiens) 6480464 Dinoprostone inhibits the reaction [Celecoxib inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]] CTD PMID:29396848 quercetin decreases expression ISO SOX2 (Homo sapiens) 6480464 Quercetin results in decreased expression of SOX2 protein CTD PMID:27468969 remdesivir decreases expression ISO Sox2 (Mus musculus) 6480464 remdesivir results in decreased expression of SOX2 mRNA CTD PMID:35605700 resveratrol decreases expression ISO SOX2 (Homo sapiens) 6480464 resveratrol results in decreased expression of SOX2 mRNA and resveratrol results in decreased expression of SOX2 protein CTD PMID:21304978 and PMID:23651583 SB 431542 multiple interactions ISO SOX2 (Homo sapiens) 6480464 [4-(5-benzo(1 more ... CTD PMID:27188386 more ... serpentine asbestos affects methylation ISO SOX2 (Homo sapiens) 6480464 Asbestos and Serpentine affects the methylation of SOX2 exon CTD PMID:29523930 silicon dioxide decreases expression ISO SOX2 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of SOX2 mRNA and Silicon Dioxide results in decreased expression of SOX2 protein CTD PMID:25895662 and PMID:35288261 silicon dioxide multiple interactions ISO SOX2 (Homo sapiens) 6480464 BMI1 protein inhibits the reaction [Silicon Dioxide results in decreased expression of SOX2 protein] CTD PMID:35288261 silver atom decreases expression ISO SOX2 (Homo sapiens) 6480464 Silver results in decreased expression of SOX2 mRNA CTD PMID:26551752 silver atom decreases expression ISO Sox2 (Mus musculus) 6480464 Silver results in decreased expression of SOX2 mRNA CTD PMID:27131904 silver(0) decreases expression ISO SOX2 (Homo sapiens) 6480464 Silver results in decreased expression of SOX2 mRNA CTD PMID:26551752 silver(0) decreases expression ISO Sox2 (Mus musculus) 6480464 Silver results in decreased expression of SOX2 mRNA CTD PMID:27131904 sirolimus increases expression ISO Sox2 (Mus musculus) 6480464 Sirolimus results in increased expression of SOX2 mRNA CTD PMID:21681844 sodium arsenate multiple interactions ISO SOX2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SOX2 mRNA CTD PMID:32525701 sodium arsenite multiple interactions ISO SOX2 (Homo sapiens) 6480464 MIR155 mRNA affects the reaction [sodium arsenite results in increased expression of SOX2 protein] more ... CTD PMID:23219847 and PMID:29240254 sodium arsenite affects expression ISO SOX2 (Homo sapiens) 6480464 sodium arsenite affects the expression of SOX2 mRNA CTD PMID:29319823 sodium arsenite increases expression ISO Sox2 (Mus musculus) 6480464 sodium arsenite results in increased expression of SOX2 mRNA CTD PMID:26438402 sodium arsenite decreases expression ISO Sox2 (Mus musculus) 6480464 sodium arsenite results in decreased expression of SOX2 mRNA and sodium arsenite results in decreased expression of SOX2 protein CTD PMID:23143138 and PMID:28370166 sodium arsenite multiple interactions ISO Sox2 (Mus musculus) 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with sodium arsenite] results in decreased expression of SOX2 protein more ... CTD PMID:23143138 and PMID:26438402 sodium arsenite increases expression ISO SOX2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of SOX2 mRNA and sodium arsenite results in increased expression of SOX2 protein CTD PMID:23219847 more ... sterigmatocystin decreases expression EXP 6480464 Sterigmatocystin results in decreased expression of SOX2 mRNA CTD PMID:34126181 Tanshinone I multiple interactions EXP 6480464 tanshinone inhibits the reaction [Estrogens deficiency results in decreased expression of SOX2 protein] CTD PMID:31108107 Tanshinone I increases expression ISO Sox2 (Mus musculus) 6480464 tanshinone results in increased expression of SOX2 mRNA CTD PMID:25186638 taurocholic acid increases expression ISO Sox2 (Mus musculus) 6480464 Taurocholic Acid results in increased expression of SOX2 mRNA CTD PMID:27151938 temozolomide increases expression ISO SOX2 (Homo sapiens) 6480464 Temozolomide results in increased expression of SOX2 mRNA CTD PMID:31758290 terbufos increases methylation ISO SOX2 (Homo sapiens) 6480464 terbufos results in increased methylation of SOX2 promoter CTD PMID:22847954 Tetrachlorobisphenol A increases expression ISO SOX2 (Homo sapiens) 6480464 tetrachlorodian results in increased expression of SOX2 mRNA CTD PMID:31326446 titanium dioxide decreases expression ISO Sox2 (Mus musculus) 6480464 titanium dioxide results in decreased expression of SOX2 mRNA CTD PMID:23557971 titanium dioxide decreases expression ISO SOX2 (Homo sapiens) 6480464 titanium dioxide results in decreased expression of SOX2 mRNA CTD PMID:34973136 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of SOX2 mRNA CTD PMID:33387578 trichostatin A decreases expression ISO SOX2 (Homo sapiens) 6480464 trichostatin A results in decreased expression of SOX2 mRNA CTD PMID:24935251 and PMID:26272509 trichostatin A multiple interactions ISO SOX2 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 triclosan decreases expression ISO Sox2 (Mus musculus) 6480464 Triclosan results in decreased expression of SOX2 protein CTD PMID:24879426 triphenyl phosphate decreases expression ISO Sox2 (Mus musculus) 6480464 triphenyl phosphate results in decreased expression of SOX2 mRNA CTD PMID:35752650 Triptolide multiple interactions ISO SOX2 (Homo sapiens) 6480464 triptolide inhibits the reaction [cobaltous chloride results in increased expression of SOX2 protein] CTD PMID:24842335 Tungsten carbide multiple interactions ISO SOX2 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which results in decreased expression of SOX2 mRNA CTD PMID:20105288 urethane decreases expression ISO SOX2 (Homo sapiens) 6480464 Urethane results in decreased expression of SOX2 mRNA CTD PMID:28818685 valproic acid decreases methylation ISO SOX2 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of SOX2 gene CTD PMID:29154799 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of SOX2 mRNA CTD PMID:33150595 valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of SOX2 promoter CTD PMID:33150595 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of SOX2 mRNA CTD PMID:29427782 valproic acid multiple interactions ISO SOX2 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 valproic acid decreases expression ISO SOX2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of SOX2 mRNA CTD PMID:23179753 more ... vanadyl sulfate decreases expression ISO SOX2 (Homo sapiens) 6480464 vanadyl sulfate results in decreased expression of SOX2 mRNA CTD PMID:16330358 verapamil multiple interactions ISO SOX2 (Homo sapiens) 6480464 [Verapamil co-treated with kaempferol] results in decreased expression of SOX2 mRNA CTD PMID:35063459 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of SOX2 mRNA CTD PMID:18042343 vorinostat decreases expression ISO SOX2 (Homo sapiens) 6480464 vorinostat results in decreased expression of SOX2 mRNA CTD PMID:26272509 vorinostat multiple interactions ISO SOX2 (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 XAV939 multiple interactions ISO SOX2 (Homo sapiens) 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA and [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA CTD PMID:34480604 zoledronic acid increases expression ISO SOX2 (Homo sapiens) 6480464 zoledronic acid results in increased expression of SOX2 mRNA CTD PMID:24714768
