(20S)-ginsenoside Rg3 decreases expression ISO RGD:1344695 6480464 ginsenoside Rg3 results in decreased expression of SOX2 mRNA CTD PMID:31916386 (R)-pantothenic acid decreases expression ISO RGD:1344695 6480464 Pantothenic Acid results in decreased expression of SOX2 mRNA CTD PMID:19397697 (S)-naringenin decreases expression ISO RGD:1344695 6480464 naringenin results in decreased expression of SOX2 protein CTD PMID:27468969 1,2-dichloroethane decreases expression ISO RGD:1558014 6480464 ethylene dichloride results in decreased expression of SOX2 mRNA CTD PMID:28960355 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of SOX2 mRNA CTD PMID:30387366 17beta-estradiol decreases expression ISO RGD:1344695 6480464 Estradiol results in decreased expression of SOX2 mRNA CTD PMID:16474171 more ... 17beta-estradiol increases activity ISO RGD:1344695 6480464 Estradiol results in increased activity of SOX2 protein CTD PMID:27592001 17beta-estradiol increases expression ISO RGD:1344695 6480464 Estradiol results in increased expression of SOX2 mRNA CTD PMID:24424067 17beta-estradiol multiple interactions ISO RGD:1344695 6480464 [Arsenic co-treated with Estradiol] results in decreased expression of SOX2 mRNA, [Estradiol binds to ESR2 protein] which results in increased expression of SOX2 mRNA CTD PMID:20404318 , PMID:33047385 17beta-estradiol 3-benzoate decreases methylation EXP 6480464 estradiol 3-benzoate results in decreased methylation of SOX2 promoter CTD PMID:27415467 17beta-estradiol 3-benzoate increases expression EXP 6480464 estradiol 3-benzoate results in increased expression of SOX2 mRNA CTD PMID:27415467 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:27291303 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:1558014 6480464 2 more ... CTD PMID:34547414 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1344695 6480464 2 more ... CTD PMID:31326446 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1558014 6480464 Tetrachlorodibenzodioxin affects the expression of SOX2 mRNA CTD PMID:21570461 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1344695 6480464 Tetrachlorodibenzodioxin results in increased expression of SOX2 mRNA CTD PMID:30203000 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1344695 6480464 N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SOX2 mRNA] CTD PMID:30203000 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO RGD:1344695 6480464 [Verapamil co-treated with kaempferol] results in decreased expression of SOX2 mRNA CTD PMID:35063459 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [INS co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA CTD PMID:21350315 3-methyladenine increases expression ISO RGD:1558014 6480464 3-methyladenine results in increased expression of SOX2 mRNA CTD PMID:21681844 5-aza-2'-deoxycytidine decreases expression ISO RGD:1558014 6480464 Decitabine results in decreased expression of SOX2 mRNA CTD PMID:27915011 5-azacytidine increases expression EXP 6480464 Azacitidine results in increased expression of SOX2 mRNA CTD PMID:27415467 5-fluorouracil decreases expression ISO RGD:1558014 6480464 Fluorouracil results in decreased expression of SOX2 protein CTD PMID:21296659 acrylamide decreases expression ISO RGD:1344695 6480464 Acrylamide results in decreased expression of SOX2 mRNA, Acrylamide results in decreased expression of SOX2 protein CTD PMID:32763439 aflatoxin B1 decreases methylation ISO RGD:1344695 6480464 Aflatoxin B1 results in decreased methylation of SOX2 gene CTD PMID:27153756 aflatoxin M1 decreases expression ISO RGD:1344695 6480464 Aflatoxin M1 results in decreased expression of SOX2 mRNA CTD PMID:30928695 aldehydo-D-glucose decreases expression ISO RGD:1344695 6480464 Glucose results in decreased expression of SOX2 protein CTD PMID:33992720 all-trans-retinoic acid multiple interactions ISO RGD:1558014 6480464 NR6A1 protein affects the reaction [Tretinoin results in decreased expression of SOX2 mRNA], Tretinoin results in decreased expression of and results in increased degradation of SOX2 protein CTD PMID:16166633 , PMID:30442713 all-trans-retinoic acid multiple interactions ISO RGD:1344695 6480464 [4-(5-benzo(1 more ... CTD PMID:30093655 , PMID:31711903 all-trans-retinoic acid affects expression ISO RGD:1344695 6480464 Tretinoin affects the expression of SOX2 mRNA CTD PMID:31600526 all-trans-retinoic acid increases degradation ISO RGD:1558014 6480464 Tretinoin results in increased degradation of SOX2 protein modified form CTD PMID:30442713 all-trans-retinoic acid decreases expression ISO RGD:1344695 6480464 Tretinoin results in decreased expression of SOX2 mRNA CTD PMID:21934132 , PMID:34742744 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1344695 6480464 pyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of SOX2 protein] CTD PMID:23219847 antirheumatic drug increases expression ISO RGD:1344695 6480464 Antirheumatic Agents results in increased expression of SOX2 mRNA CTD PMID:24449571 apigenin decreases expression ISO RGD:1344695 6480464 Apigenin results in decreased expression of SOX2 protein CTD PMID:27468969 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of SOX2 mRNA CTD PMID:34858468 arotinoid acid multiple interactions ISO RGD:1344695 6480464 [4-(2-(5 more ... CTD PMID:34480604 arsane increases expression ISO RGD:1558014 6480464 Arsenic results in increased expression of SOX2 mRNA, Arsenic results in increased expression of SOX2 protein CTD PMID:23221970 , PMID:33124703 arsane multiple interactions ISO RGD:1344695 6480464 [Arsenic co-treated with Estradiol] results in decreased expression of SOX2 mRNA, [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SOX2 mRNA CTD PMID:32525701 , PMID:33047385 arsane increases expression ISO RGD:1344695 6480464 Arsenic results in increased expression of SOX2 mRNA CTD PMID:29396848 arsenic atom increases expression ISO RGD:1558014 6480464 Arsenic results in increased expression of SOX2 mRNA, Arsenic results in increased expression of SOX2 protein CTD PMID:23221970 , PMID:33124703 arsenic atom multiple interactions ISO RGD:1344695 6480464 [Arsenic co-treated with Estradiol] results in decreased expression of SOX2 mRNA, [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SOX2 mRNA CTD PMID:32525701 , PMID:33047385 arsenic atom increases expression ISO RGD:1344695 6480464 Arsenic results in increased expression of SOX2 mRNA CTD PMID:29396848 arsenite(3-) decreases expression ISO RGD:1344695 6480464 arsenite results in decreased expression of SOX2 mRNA CTD PMID:23974009 arsenous acid multiple interactions ISO RGD:1344695 6480464 4-(4-cyano-2-(2-(4-fluoronaphthalen-1-yl)propionylamino)phenyl)butyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein] more ... CTD PMID:29396848 more ... arsenous acid decreases expression ISO RGD:1344695 6480464 Arsenic Trioxide results in decreased expression of SOX2 mRNA CTD PMID:24685274 , PMID:33634982 arsenous acid decreases response to substance ISO RGD:1344695 6480464 SOX2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:21703238 arsenous acid increases expression ISO RGD:1344695 6480464 Arsenic Trioxide results in increased expression of SOX2 mRNA, Arsenic Trioxide results in increased expression of SOX2 protein CTD PMID:29396848 , PMID:29486283 aspartame affects localization ISO RGD:1344695 6480464 Aspartame affects the localization of SOX2 protein CTD PMID:33992720 benzo[a]pyrene decreases expression ISO RGD:1558014 6480464 Benzo(a)pyrene results in decreased expression of SOX2 mRNA CTD PMID:22228805 , PMID:27195522 benzo[a]pyrene decreases expression ISO RGD:1344695 6480464 Benzo(a)pyrene results in decreased expression of SOX2 mRNA, Benzo(a)pyrene results in decreased expression of SOX2 protein CTD PMID:30659931 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1344695 6480464 Diethylhexyl Phthalate results in decreased expression of SOX2 mRNA CTD PMID:31163220 bisphenol A decreases expression ISO RGD:1344695 6480464 bisphenol A results in decreased expression of SOX2 mRNA CTD PMID:16474171 , PMID:25051057 bisphenol A decreases expression ISO RGD:1558014 6480464 bisphenol A results in decreased expression of SOX2 mRNA CTD PMID:35219798 bisphenol A multiple interactions ISO RGD:1344695 6480464 bisphenol A promotes the reaction [CREB1 protein modified form binds to SOX2 enhancer] CTD PMID:28244015 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SOX2 mRNA CTD PMID:27415467 , PMID:30387366 bisphenol A affects methylation ISO RGD:1558014 6480464 bisphenol A affects the methylation of SOX2 promoter CTD PMID:27334623 bisphenol A increases expression ISO RGD:1344695 6480464 bisphenol A results in increased expression of SOX2 mRNA, bisphenol A results in increased expression of SOX2 protein CTD PMID:28244015 , PMID:35069845 bisphenol A affects methylation EXP 6480464 bisphenol A affects the methylation of SOX2 promoter CTD PMID:27415467 bisphenol A decreases methylation EXP 6480464 bisphenol A results in decreased methylation of SOX2 promoter CTD PMID:28728135 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SOX2 mRNA CTD PMID:25181051 , PMID:29097150 bisphenol A increases expression ISO RGD:1558014 6480464 bisphenol A results in increased expression of SOX2 mRNA, bisphenol A results in increased expression of SOX2 protein CTD PMID:23719110 more ... bromochloroacetic acid affects expression ISO RGD:1558014 6480464 bromochloroacetic acid affects the expression of SOX2 protein CTD PMID:21296659 buta-1,3-diene decreases expression ISO RGD:1558014 6480464 1, 3-butadiene results in decreased expression of SOX2 mRNA CTD PMID:29038090 butanal decreases expression ISO RGD:1344695 6480464 butyraldehyde results in decreased expression of SOX2 mRNA CTD PMID:26079696 cadmium dichloride affects expression ISO RGD:1558014 6480464 Cadmium Chloride affects the expression of SOX2 mRNA CTD PMID:18974090 cadmium sulfate increases expression ISO RGD:1558014 6480464 cadmium sulfate results in increased expression of SOX2 mRNA CTD PMID:19274763 carbofuran decreases expression EXP 6480464 Carbofuran results in decreased expression of SOX2 protein CTD PMID:22240977 carbon atom multiple interactions ISO RGD:1344695 6480464 [Air Pollutants results in increased abundance of Carbon] which results in decreased expression of SOX2 mRNA CTD PMID:31791492 carbon nanotube decreases expression ISO RGD:1558014 6480464 Nanotubes, Carbon analog results in decreased expression of SOX2 mRNA CTD PMID:25554681 carboplatin increases expression ISO RGD:1344695 6480464 Carboplatin results in increased expression of SOX2 mRNA CTD PMID:25605917 carvedilol increases expression EXP 6480464 carvedilol results in increased expression of SOX2 mRNA CTD PMID:27288437 carvedilol increases expression ISO RGD:1558014 6480464 carvedilol results in increased expression of SOX2 mRNA CTD PMID:27288437 celecoxib multiple interactions ISO RGD:1344695 6480464 Celecoxib inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein], Dinoprostone inhibits the reaction [Celecoxib inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]] CTD PMID:29396848 CGP 52608 multiple interactions ISO RGD:1344695 6480464 CGP 52608 promotes the reaction [RORA protein binds to SOX2 gene] CTD PMID:28238834 CHIR 99021 decreases expression ISO RGD:1344695 6480464 Chir 99021 results in decreased expression of SOX2 mRNA CTD PMID:31711903 CHIR 99021 multiple interactions ISO RGD:1344695 6480464 [4-(2-(5 more ... CTD PMID:31711903 , PMID:34480604 chlordecone increases expression ISO RGD:1558014 6480464 Chlordecone results in increased expression of SOX2 mRNA CTD PMID:33711761 chloroprene increases expression ISO RGD:1558014 6480464 Chloroprene results in increased expression of SOX2 mRNA CTD PMID:23125180 chlorpromazine decreases expression ISO RGD:1344695 6480464 Chlorpromazine results in decreased expression of SOX2 mRNA CTD PMID:30703373 chromium(6+) multiple interactions ISO RGD:1558014 6480464 MAP2K7 protein promotes the reaction [chromium hexavalent ion results in increased expression of SOX2 mRNA] CTD PMID:19654923 chromium(6+) increases expression ISO RGD:1558014 6480464 chromium hexavalent ion results in increased expression of SOX2 mRNA CTD PMID:19654923 chrysene increases expression ISO RGD:1558014 6480464 chrysene results in increased expression of SOX2 mRNA CTD PMID:26377693 ciprofloxacin decreases expression ISO RGD:1344695 6480464 Ciprofloxacin results in decreased expression of SOX2 protein CTD PMID:26947806 cisplatin multiple interactions ISO RGD:1344695 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of SOX2 mRNA more ... CTD PMID:20705681 more ... Citreoviridin increases expression ISO RGD:1558014 6480464 citreoviridin results in increased expression of SOX2 mRNA CTD PMID:30071239 cobalt atom multiple interactions ISO RGD:1344695 6480464 [tungsten carbide binds to Cobalt] which results in decreased expression of SOX2 mRNA CTD PMID:20105288 cobalt dichloride multiple interactions ISO RGD:1344695 6480464 [EPAS1 protein results in increased susceptibility to cobaltous chloride] which results in increased expression of SOX2 mRNA more ... CTD PMID:24842335 , PMID:25805230 cobalt dichloride decreases expression ISO RGD:1344695 6480464 cobaltous chloride results in decreased expression of SOX2 mRNA CTD PMID:20105288 cobalt dichloride increases expression ISO RGD:1344695 6480464 cobaltous chloride results in increased expression of SOX2 protein CTD PMID:24842335 colforsin daropate hydrochloride decreases expression ISO RGD:1344695 6480464 Colforsin results in decreased expression of SOX2 protein CTD PMID:34897981 cortisol multiple interactions ISO RGD:1344695 6480464 [4-(2-(5 more ... CTD PMID:34480604 crystal violet multiple interactions ISO RGD:1344695 6480464 [Gentian Violet results in decreased phosphorylation of and affects the localization of STAT3 protein] inhibits the reaction [STAT3 protein binds to SOX2 promoter] CTD PMID:27373978 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of SOX2 mRNA CTD PMID:27523638 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of SOX2 mRNA CTD PMID:26577399 curcumin increases expression ISO RGD:1558014 6480464 Curcumin results in increased expression of SOX2 mRNA, Curcumin results in increased expression of SOX2 protein CTD PMID:25822711 D-glucose decreases expression ISO RGD:1344695 6480464 Glucose results in decreased expression of SOX2 protein CTD PMID:33992720 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of SOX2 mRNA CTD PMID:23640034 decabromodiphenyl ether decreases expression ISO RGD:1344695 6480464 decabromobiphenyl ether results in decreased expression of SOX2 mRNA CTD PMID:26206603 decabromodiphenyl ether increases expression ISO RGD:1344695 6480464 decabromobiphenyl ether results in increased expression of SOX2 mRNA CTD PMID:31326446 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of SOX2 mRNA CTD PMID:23640034 deoxycholic acid increases expression ISO RGD:1558014 6480464 Deoxycholic Acid results in increased expression of SOX2 mRNA CTD PMID:27151938 dexamethasone multiple interactions EXP 6480464 [INS co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA, MIR134 mRNA affects the reaction [Dexamethasone results in decreased expression of SOX2 mRNA] CTD PMID:21350315 , PMID:33619658 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of SOX2 mRNA, Dexamethasone results in decreased expression of SOX2 protein CTD PMID:33619658 dexamethasone multiple interactions ISO RGD:1558014 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA CTD PMID:28189605 diarsenic trioxide increases expression ISO RGD:1344695 6480464 Arsenic Trioxide results in increased expression of SOX2 mRNA, Arsenic Trioxide results in increased expression of SOX2 protein CTD PMID:29396848 , PMID:29486283 diarsenic trioxide multiple interactions ISO RGD:1344695 6480464 4-(4-cyano-2-(2-(4-fluoronaphthalen-1-yl)propionylamino)phenyl)butyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein] more ... CTD PMID:29396848 more ... diarsenic trioxide decreases expression ISO RGD:1344695 6480464 Arsenic Trioxide results in decreased expression of SOX2 mRNA CTD PMID:24685274 , PMID:33634982 diarsenic trioxide decreases response to substance ISO RGD:1344695 6480464 SOX2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:21703238 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of SOX2 mRNA CTD PMID:17005392 dioxygen increases expression ISO RGD:1344695 6480464 [Oxygen deficiency results in increased expression of CA9 mRNA] which results in increased expression of SOX2 mRNA CTD PMID:26305601 dorsomorphin multiple interactions ISO RGD:1344695 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 eckol decreases expression ISO RGD:1344695 6480464 eckol results in decreased expression of SOX2 protein CTD PMID:21514314 elemental carbon multiple interactions ISO RGD:1344695 6480464 [Air Pollutants results in increased abundance of Carbon] which results in decreased expression of SOX2 mRNA CTD PMID:31791492 ethanol increases expression EXP 6480464 Ethanol results in increased expression of SOX2 mRNA, Ethanol results in increased expression of SOX2 protein CTD PMID:29769550 etodolac multiple interactions ISO RGD:1344695 6480464 Etodolac inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein] CTD PMID:29396848 etoposide multiple interactions ISO RGD:1344695 6480464 FTL protein affects the reaction [Etoposide results in increased expression of SOX2 protein] CTD PMID:33969609 fluoxetine affects expression ISO RGD:1558014 6480464 Fluoxetine affects the expression of SOX2 mRNA CTD PMID:29893963 flurbiprofen increases expression ISO RGD:1558014 6480464 Flurbiprofen results in increased expression of SOX2 mRNA CTD PMID:16949054 folic acid decreases expression ISO RGD:1558014 6480464 Folic Acid results in decreased expression of SOX2 mRNA CTD PMID:25629700 fonofos increases methylation ISO RGD:1344695 6480464 Fonofos results in increased methylation of SOX2 promoter CTD PMID:22847954 formaldehyde decreases expression ISO RGD:1344695 6480464 Formaldehyde results in decreased expression of SOX2 mRNA CTD PMID:20655997 gemcitabine increases expression ISO RGD:1344695 6480464 Gemcitabine results in increased expression of SOX2 mRNA CTD PMID:25605917 genistein decreases expression ISO RGD:1344695 6480464 Genistein results in decreased expression of SOX2 mRNA CTD PMID:16474171 glucose decreases expression ISO RGD:1344695 6480464 Glucose results in decreased expression of SOX2 protein CTD PMID:33992720 glycerol 2-phosphate multiple interactions ISO RGD:1558014 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA CTD PMID:28189605 GS-441524 increases expression ISO RGD:1558014 6480464 GS-441524 results in increased expression of SOX2 mRNA CTD PMID:35605700 hexachlorophene decreases expression ISO RGD:1558014 6480464 Hexachlorophene results in decreased expression of SOX2 mRNA, Hexachlorophene results in decreased expression of SOX2 protein CTD PMID:25943520 hydroquinone decreases expression ISO RGD:1344695 6480464 hydroquinone results in decreased expression of SOX2 mRNA CTD PMID:31256213 isoorientin decreases expression ISO RGD:1344695 6480464 homoorientin results in decreased expression of SOX2 protein CTD PMID:34019859 ivermectin decreases expression ISO RGD:1344695 6480464 Ivermectin results in decreased expression of SOX2 mRNA, Ivermectin results in decreased expression of SOX2 protein CTD PMID:29257278 kaempferol decreases expression ISO RGD:1344695 6480464 kaempferol results in decreased expression of SOX2 mRNA CTD PMID:35063459 kaempferol multiple interactions ISO RGD:1344695 6480464 [Verapamil co-treated with kaempferol] results in decreased expression of SOX2 mRNA CTD PMID:35063459 L-ascorbic acid increases expression ISO RGD:1344695 6480464 Ascorbic Acid results in increased expression of SOX2 mRNA CTD PMID:21166886 L-ascorbic acid multiple interactions ISO RGD:1344695 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA CTD PMID:34480604 L-ascorbic acid multiple interactions ISO RGD:1558014 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SOX2 mRNA CTD PMID:28189605 L-ascorbic acid 2-phosphate multiple interactions ISO RGD:1344695 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA CTD PMID:34480604 lapatinib multiple interactions ISO RGD:1344695 6480464 [lapatinib results in decreased susceptibility to lapatinib] which results in increased expression of SOX2 protein CTD PMID:26643609 lead diacetate increases expression ISO RGD:1558014 6480464 lead acetate results in increased expression of SOX2 mRNA CTD PMID:31715224 lupeol decreases expression ISO RGD:1558014 6480464 lupeol results in decreased expression of SOX2 protein CTD PMID:20979057 LY294002 multiple interactions ISO RGD:1558014 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with sodium arsenite] results in decreased expression of SOX2 protein CTD PMID:23143138 LY294002 decreases expression ISO RGD:1558014 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of SOX2 protein CTD PMID:23143138 mercury dibromide decreases expression ISO RGD:1344695 6480464 mercuric bromide results in decreased expression of SOX2 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:1344695 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 methylmercury chloride decreases expression ISO RGD:1344695 6480464 methylmercuric chloride results in decreased expression of SOX2 mRNA CTD PMID:28001369 methylmercury chloride increases expression ISO RGD:1344695 6480464 methylmercuric chloride results in increased expression of SOX2 mRNA, methylmercuric chloride results in increased expression of SOX2 protein CTD PMID:34328791 methylparaben increases expression ISO RGD:1344695 6480464 methylparaben results in increased expression of SOX2 mRNA CTD PMID:27581495 miconazole increases expression ISO RGD:1558014 6480464 Miconazole results in increased expression of SOX2 mRNA CTD PMID:27462272 naphthalene increases expression ISO RGD:1558014 6480464 naphthalene results in increased expression of SOX2 protein CTD PMID:16239640 nickel dichloride increases expression ISO RGD:1344695 6480464 nickel chloride results in increased expression of SOX2 protein CTD PMID:26962057 Nonylphenol increases expression ISO RGD:1558014 6480464 nonylphenol results in increased expression of SOX2 mRNA CTD PMID:31288075 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of SOX2 mRNA CTD PMID:21703336 ochratoxin A multiple interactions EXP 6480464 SHH protein modified form inhibits the reaction [ochratoxin A results in decreased expression of SOX2 mRNA] CTD PMID:21703336 ozone multiple interactions ISO RGD:1558014 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SOX2 mRNA CTD PMID:34911549 p-chloromercuribenzoic acid decreases expression ISO RGD:1344695 6480464 p-Chloromercuribenzoic Acid results in decreased expression of SOX2 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:1344695 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 paclitaxel multiple interactions ISO RGD:1344695 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of SOX2 mRNA CTD PMID:20705681 panobinostat multiple interactions ISO RGD:1344695 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 panobinostat decreases expression ISO RGD:1344695 6480464 panobinostat results in decreased expression of SOX2 mRNA CTD PMID:26272509 paracetamol increases expression ISO RGD:1344695 6480464 Acetaminophen results in increased expression of SOX2 mRNA CTD PMID:26690555 paraquat decreases expression ISO RGD:1558014 6480464 Paraquat results in decreased expression of SOX2 mRNA CTD PMID:21463325 parathion increases methylation ISO RGD:1344695 6480464 Parathion results in increased methylation of SOX2 promoter CTD PMID:22847954 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1558014 6480464 perfluorooctane sulfonic acid results in decreased expression of SOX2 mRNA, perfluorooctane sulfonic acid results in decreased expression of SOX2 protein CTD PMID:24098361 perfluorooctane-1-sulfonic acid increases expression ISO RGD:1558014 6480464 perfluorooctane sulfonic acid results in increased expression of SOX2 mRNA, perfluorooctane sulfonic acid results in increased expression of SOX2 protein CTD PMID:25510869 phenylephrine multiple interactions EXP 6480464 Phenylephrine inhibits the reaction [Iodine-131 inhibits the reaction [PAFAH1B1 protein binds to SOX2 protein]] CTD PMID:32278511 phenylmercury acetate decreases expression ISO RGD:1344695 6480464 Phenylmercuric Acetate results in decreased expression of SOX2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1344695 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 poly(I:C) increases expression ISO RGD:1344695 6480464 Poly I-C results in increased expression of SOX2 protein CTD PMID:29486283 poly(I:C) multiple interactions ISO RGD:1344695 6480464 Poly I-C promotes the reaction [MSI1 protein results in increased expression of SOX2 protein] CTD PMID:29486283 prostaglandin E2 multiple interactions ISO RGD:1344695 6480464 Dinoprostone inhibits the reaction [Celecoxib inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]] CTD PMID:29396848 quercetin decreases expression ISO RGD:1344695 6480464 Quercetin results in decreased expression of SOX2 protein CTD PMID:27468969 remdesivir decreases expression ISO RGD:1558014 6480464 remdesivir results in decreased expression of SOX2 mRNA CTD PMID:35605700 resveratrol decreases expression ISO RGD:1344695 6480464 resveratrol results in decreased expression of SOX2 mRNA, resveratrol results in decreased expression of SOX2 protein CTD PMID:21304978 , PMID:23651583 SB 431542 multiple interactions ISO RGD:1344695 6480464 [4-(5-benzo(1 more ... CTD PMID:27188386 more ... serpentine asbestos affects methylation ISO RGD:1344695 6480464 Asbestos, Serpentine affects the methylation of SOX2 exon CTD PMID:29523930 silicon dioxide decreases expression ISO RGD:1344695 6480464 Silicon Dioxide analog results in decreased expression of SOX2 mRNA, Silicon Dioxide results in decreased expression of SOX2 protein CTD PMID:25895662 , PMID:35288261 silicon dioxide multiple interactions ISO RGD:1344695 6480464 BMI1 protein inhibits the reaction [Silicon Dioxide results in decreased expression of SOX2 protein] CTD PMID:35288261 silver atom decreases expression ISO RGD:1344695 6480464 Silver results in decreased expression of SOX2 mRNA CTD PMID:26551752 silver atom decreases expression ISO RGD:1558014 6480464 Silver results in decreased expression of SOX2 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:1344695 6480464 Silver results in decreased expression of SOX2 mRNA CTD PMID:26551752 silver(0) decreases expression ISO RGD:1558014 6480464 Silver results in decreased expression of SOX2 mRNA CTD PMID:27131904 sirolimus increases expression ISO RGD:1558014 6480464 Sirolimus results in increased expression of SOX2 mRNA CTD PMID:21681844 sodium arsenate multiple interactions ISO RGD:1344695 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SOX2 mRNA CTD PMID:32525701 sodium arsenite multiple interactions ISO RGD:1344695 6480464 MIR155 mRNA affects the reaction [sodium arsenite results in increased expression of SOX2 protein] more ... CTD PMID:23219847 , PMID:29240254 sodium arsenite affects expression ISO RGD:1344695 6480464 sodium arsenite affects the expression of SOX2 mRNA CTD PMID:29319823 sodium arsenite increases expression ISO RGD:1558014 6480464 sodium arsenite results in increased expression of SOX2 mRNA CTD PMID:26438402 sodium arsenite decreases expression ISO RGD:1558014 6480464 sodium arsenite results in decreased expression of SOX2 mRNA, sodium arsenite results in decreased expression of SOX2 protein CTD PMID:23143138 , PMID:28370166 sodium arsenite multiple interactions ISO RGD:1558014 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with sodium arsenite] results in decreased expression of SOX2 protein more ... CTD PMID:23143138 , PMID:26438402 sodium arsenite increases expression ISO RGD:1344695 6480464 sodium arsenite results in increased expression of SOX2 mRNA, sodium arsenite results in increased expression of SOX2 protein CTD PMID:23219847 more ... sterigmatocystin decreases expression EXP 6480464 Sterigmatocystin results in decreased expression of SOX2 mRNA CTD PMID:34126181 Tanshinone I multiple interactions EXP 6480464 tanshinone inhibits the reaction [Estrogens deficiency results in decreased expression of SOX2 protein] CTD PMID:31108107 Tanshinone I increases expression ISO RGD:1558014 6480464 tanshinone results in increased expression of SOX2 mRNA CTD PMID:25186638 taurocholic acid increases expression ISO RGD:1558014 6480464 Taurocholic Acid results in increased expression of SOX2 mRNA CTD PMID:27151938 temozolomide increases expression ISO RGD:1344695 6480464 Temozolomide results in increased expression of SOX2 mRNA CTD PMID:31758290 terbufos increases methylation ISO RGD:1344695 6480464 terbufos results in increased methylation of SOX2 promoter CTD PMID:22847954 Tetrachlorobisphenol A increases expression ISO RGD:1344695 6480464 tetrachlorodian results in increased expression of SOX2 mRNA CTD PMID:31326446 titanium dioxide decreases expression ISO RGD:1558014 6480464 titanium dioxide results in decreased expression of SOX2 mRNA CTD PMID:23557971 titanium dioxide decreases expression ISO RGD:1344695 6480464 titanium dioxide results in decreased expression of SOX2 mRNA CTD PMID:34973136 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of SOX2 mRNA CTD PMID:33387578 trichostatin A decreases expression ISO RGD:1344695 6480464 trichostatin A results in decreased expression of SOX2 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:1344695 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 triclosan decreases expression ISO RGD:1558014 6480464 Triclosan results in decreased expression of SOX2 protein CTD PMID:24879426 triphenyl phosphate decreases expression ISO RGD:1558014 6480464 triphenyl phosphate results in decreased expression of SOX2 mRNA CTD PMID:35752650 Triptolide multiple interactions ISO RGD:1344695 6480464 triptolide inhibits the reaction [cobaltous chloride results in increased expression of SOX2 protein] CTD PMID:24842335 Tungsten carbide multiple interactions ISO RGD:1344695 6480464 [tungsten carbide binds to Cobalt] which results in decreased expression of SOX2 mRNA CTD PMID:20105288 urethane decreases expression ISO RGD:1344695 6480464 Urethane results in decreased expression of SOX2 mRNA CTD PMID:28818685 valproic acid decreases methylation ISO RGD:1344695 6480464 Valproic Acid results in decreased methylation of SOX2 gene CTD PMID:29154799 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of SOX2 mRNA CTD PMID:29427782 valproic acid multiple interactions ISO RGD:1344695 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 valproic acid decreases expression ISO RGD:1344695 6480464 Valproic Acid results in decreased expression of SOX2 mRNA CTD PMID:23179753 more ... vanadyl sulfate decreases expression ISO RGD:1344695 6480464 vanadyl sulfate results in decreased expression of SOX2 mRNA CTD PMID:16330358 verapamil multiple interactions ISO RGD:1344695 6480464 [Verapamil co-treated with kaempferol] results in decreased expression of SOX2 mRNA CTD PMID:35063459 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of SOX2 mRNA CTD PMID:18042343 vorinostat decreases expression ISO RGD:1344695 6480464 vorinostat results in decreased expression of SOX2 mRNA CTD PMID:26272509 vorinostat multiple interactions ISO RGD:1344695 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX2 mRNA CTD PMID:27188386 XAV939 multiple interactions ISO RGD:1344695 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA, [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA CTD PMID:34480604 zoledronic acid increases expression ISO RGD:1344695 6480464 zoledronic acid results in increased expression of SOX2 mRNA CTD PMID:24714768
