Crebzf (CREB/ATF bZIP transcription factor) - Rat Genome Database

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Gene: Crebzf (CREB/ATF bZIP transcription factor) Rattus norvegicus
Analyze
Symbol: Crebzf
Name: CREB/ATF bZIP transcription factor
RGD ID: 1565584
Description: Predicted to enable identical protein binding activity. Predicted to be involved in negative regulation of gene expression, epigenetic; regulation of DNA-templated transcription; and response to virus. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human CREBZF (CREB/ATF bZIP transcription factor); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC293112; RGD1565584; similar to tyrosine kinase-associated leucine zipper protein LAZipII
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81153,829,544 - 153,836,073 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1153,829,448 - 153,845,122 (+)EnsemblGRCr8
mRatBN7.21144,416,864 - 144,423,540 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1144,417,446 - 144,428,553 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1152,340,025 - 152,346,332 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01159,521,180 - 159,527,509 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01152,395,099 - 152,401,428 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01156,290,215 - 156,296,891 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1156,294,519 - 156,296,161 (-)Ensemblrn6Rnor6.0
Rnor_5.01162,536,337 - 162,543,012 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41147,124,224 - 147,129,115 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1142,637,629 - 142,643,940 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[ghi]perylene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
ethanol  (ISO)
finasteride  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen peroxide  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
potassium chromate  (ISO)
resveratrol  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
tamoxifen  (ISO)
tetraphene  (ISO)
tetrathiomolybdate(2-)  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10871379   PMID:15705566   PMID:16343488   PMID:19690166   PMID:20102225   PMID:21994947   PMID:22387546   PMID:24155933  


Genomics

Comparative Map Data
Crebzf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81153,829,544 - 153,836,073 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1153,829,448 - 153,845,122 (+)EnsemblGRCr8
mRatBN7.21144,416,864 - 144,423,540 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1144,417,446 - 144,428,553 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1152,340,025 - 152,346,332 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01159,521,180 - 159,527,509 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01152,395,099 - 152,401,428 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01156,290,215 - 156,296,891 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1156,294,519 - 156,296,161 (-)Ensemblrn6Rnor6.0
Rnor_5.01162,536,337 - 162,543,012 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41147,124,224 - 147,129,115 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1142,637,629 - 142,643,940 (+)NCBICelera
Cytogenetic Map1q32NCBI
CREBZF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381185,657,990 - 85,682,863 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1185,657,742 - 85,682,908 (-)Ensemblhg38GRCh38
GRCh371185,369,034 - 85,393,906 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361185,046,518 - 85,053,821 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1182,677,923 - 82,685,497 (-)NCBICelera
Cytogenetic Map11q14.1NCBI
HuRef1181,665,902 - 81,673,477 (-)NCBIHuRef
CHM1_11185,253,399 - 85,260,973 (-)NCBICHM1_1
T2T-CHM13v2.01185,594,499 - 85,619,547 (-)NCBIT2T-CHM13v2.0
Crebzf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39790,091,942 - 90,097,590 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl790,091,937 - 90,097,202 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38790,442,734 - 90,448,382 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl790,442,729 - 90,447,994 (+)Ensemblmm10GRCm38
MGSCv37797,591,291 - 97,596,231 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36790,318,764 - 90,319,967 (+)NCBIMGSCv36mm8
Celera787,770,260 - 87,775,205 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map750.59NCBI
Crebzf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554147,206,343 - 7,209,498 (+)Ensembl
ChiLan1.0NW_0049554147,190,234 - 7,213,042 (+)NCBIChiLan1.0ChiLan1.0
CREBZF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2986,581,031 - 86,588,855 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11187,632,824 - 87,639,194 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01180,713,916 - 80,721,085 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11184,322,496 - 84,329,636 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1184,322,496 - 84,329,636 (-)EnsemblpanPan2panpan1.1
CREBZF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12113,777,768 - 13,783,396 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2113,644,435 - 13,650,065 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02113,958,572 - 13,964,211 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UNSW_CanFamBas_1.02113,819,417 - 13,825,044 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02113,872,170 - 13,877,811 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Crebzf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494771,934,378 - 71,954,222 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649813,548,422 - 13,553,725 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649813,547,968 - 13,553,846 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CREBZF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl919,593,737 - 19,594,801 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1919,589,617 - 19,595,114 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2921,859,748 - 21,865,248 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CREBZF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1176,899,308 - 76,906,681 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl176,905,129 - 76,906,193 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604348,815,014 - 48,823,354 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crebzf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248454,256,179 - 4,261,401 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248454,256,274 - 4,262,461 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Crebzf
25 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:327
Count of miRNA genes:223
Interacting mature miRNAs:248
Transcripts:ENSRNOT00000025653
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1103111621148111621Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1123556856242907031Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1117917486196963478Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
2317833Alcrsp19Alcohol response QTL 1912.40.001response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
631202Gluco13Glucose level QTL 130.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1131763437159756369Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1136745990163747690Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
1641897Alcrsp1Alcohol response QTL 1response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
9685799Bp375Blood pressure QTL 375arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121833674166833674Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
61370Mcs3Mammary carcinoma susceptibility QTL 32.15mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1102268556147268556Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1106047847151047847Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1144267916172949660Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144267916174133260Rat
2303591Gluco41Glucose level QTL 412blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1102168504147168504Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
2313060Bss71Bone structure and strength QTL 712.60.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1118944747163944747Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501168883176Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1103111621148111621Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1102813953151162766Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1123556856196963478Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat

Markers in Region
RH144003  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21144,417,338 - 144,417,531 (-)MAPPERmRatBN7.2
Rnor_6.01156,296,224 - 156,296,416NCBIRnor6.0
Rnor_5.01162,542,346 - 162,542,538UniSTSRnor5.0
RGSC_v3.41147,123,971 - 147,124,163UniSTSRGSC3.4
Celera1142,637,739 - 142,637,931UniSTS
RH 3.4 Map11127.8UniSTS
Cytogenetic Map1q32UniSTS
RH141969  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21144,422,352 - 144,422,539 (-)MAPPERmRatBN7.2
Rnor_6.01156,291,216 - 156,291,402NCBIRnor6.0
Rnor_5.01162,537,338 - 162,537,524UniSTSRnor5.0
RGSC_v3.41147,128,985 - 147,129,171UniSTSRGSC3.4
Celera1142,642,753 - 142,642,939UniSTS
RH 3.4 Map11129.0UniSTS
Cytogenetic Map1q32UniSTS
AA893197  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21144,423,058 - 144,423,266 (-)MAPPERmRatBN7.2
Rnor_6.01156,290,489 - 156,290,696NCBIRnor6.0
Rnor_5.01162,536,611 - 162,536,818UniSTSRnor5.0
RGSC_v3.41147,129,691 - 147,129,898UniSTSRGSC3.4
Celera1142,643,459 - 142,643,666UniSTS
RH 3.4 Map11129.1UniSTS
Cytogenetic Map1q32UniSTS
AI236486  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21144,421,135 - 144,421,252 (-)MAPPERmRatBN7.2
Rnor_6.01156,292,503 - 156,292,619NCBIRnor6.0
Rnor_5.01162,538,625 - 162,538,741UniSTSRnor5.0
RGSC_v3.41147,127,768 - 147,127,884UniSTSRGSC3.4
Celera1142,641,536 - 142,641,652UniSTS
RH 3.4 Map11127.1UniSTS
Cytogenetic Map1q32UniSTS
Crebzf  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21144,420,970 - 144,421,980 (-)MAPPERmRatBN7.2
Rnor_6.01156,291,775 - 156,292,784NCBIRnor6.0
Rnor_5.01162,537,897 - 162,538,906UniSTSRnor5.0
Celera1142,641,371 - 142,642,380UniSTS
Cytogenetic Map1q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000025653   ⟹   ENSRNOP00000025653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1144,417,446 - 144,423,454 (+)Ensembl
Rnor_6.0 Ensembl1156,294,519 - 156,296,161 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104785   ⟹   ENSRNOP00000081742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1153,829,948 - 153,844,254 (+)Ensembl
mRatBN7.2 Ensembl1144,417,446 - 144,428,553 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000165812   ⟹   ENSRNOP00000103660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1153,829,448 - 153,845,122 (+)Ensembl
RefSeq Acc Id: NM_001271791   ⟹   NP_001258720
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,829,762 - 153,836,073 (+)NCBI
mRatBN7.21144,417,229 - 144,423,540 (+)NCBI
Rnor_6.01156,290,215 - 156,296,526 (-)NCBI
Rnor_5.01162,536,337 - 162,543,012 (-)NCBI
Celera1142,637,629 - 142,643,940 (+)NCBI
Sequence:
RefSeq Acc Id: NR_073439
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,829,762 - 153,836,073 (+)NCBI
mRatBN7.21144,417,229 - 144,423,540 (+)NCBI
Rnor_6.01156,290,215 - 156,296,526 (-)NCBI
Rnor_5.01162,536,337 - 162,543,012 (-)NCBI
Celera1142,637,629 - 142,643,940 (+)NCBI
Sequence:
RefSeq Acc Id: NR_073440
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,829,762 - 153,836,073 (+)NCBI
mRatBN7.21144,417,229 - 144,423,540 (+)NCBI
Rnor_6.01156,290,215 - 156,296,526 (-)NCBI
Rnor_5.01162,536,337 - 162,543,012 (-)NCBI
Celera1142,637,629 - 142,643,940 (+)NCBI
Sequence:
RefSeq Acc Id: NR_073441
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,829,762 - 153,836,073 (+)NCBI
mRatBN7.21144,417,229 - 144,423,540 (+)NCBI
Rnor_6.01156,290,215 - 156,296,526 (-)NCBI
Rnor_5.01162,536,337 - 162,543,012 (-)NCBI
Celera1142,637,629 - 142,643,940 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008759646   ⟹   XP_008757868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,829,544 - 153,835,837 (+)NCBI
mRatBN7.21144,416,864 - 144,423,540 (+)NCBI
Rnor_6.01156,292,226 - 156,296,891 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001258720 (Get FASTA)   NCBI Sequence Viewer  
  XP_008757868 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM18542 (Get FASTA)   NCBI Sequence Viewer  
  EDM18543 (Get FASTA)   NCBI Sequence Viewer  
  EDM18544 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025653.3
  ENSRNOP00000081742
  ENSRNOP00000081742.1
RefSeq Acc Id: NP_001258720   ⟸   NM_001271791
- UniProtKB: A0A8I6G6F0 (UniProtKB/TrEMBL),   A6I638 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008757868   ⟸   XM_008759646
- Peptide Label: isoform X1
- UniProtKB: D3ZU42 (UniProtKB/TrEMBL),   A6I636 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025653   ⟸   ENSRNOT00000025653
Ensembl Acc Id: ENSRNOP00000081742   ⟸   ENSRNOT00000104785
Ensembl Acc Id: ENSRNOP00000103660   ⟸   ENSRNOT00000165812
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZU42-F1-model_v2 AlphaFold D3ZU42 1-359 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690196
Promoter ID:EPDNEW_R716
Type:initiation region
Name:Crebzf_1
Description:CREB/ATF bZIP transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01156,296,227 - 156,296,287EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565584 AgrOrtholog
BioCyc Gene G2FUF-58528 BioCyc
Ensembl Genes ENSRNOG00000018987 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025653.6 UniProtKB/TrEMBL
  ENSRNOT00000104785 ENTREZGENE
  ENSRNOT00000104785.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
InterPro bZIP_sf UniProtKB/TrEMBL
  TF_bZIP UniProtKB/TrEMBL
KEGG Report rno:293112 UniProtKB/TrEMBL
NCBI Gene 293112 ENTREZGENE
Pfam bZIP_1 UniProtKB/TrEMBL
PhenoGen Crebzf PhenoGen
RatGTEx ENSRNOG00000018987 RatGTEx
Superfamily-SCOP SSF57959 UniProtKB/TrEMBL
UniProt A0A8I6G6F0 ENTREZGENE, UniProtKB/TrEMBL
  A6I636 ENTREZGENE, UniProtKB/TrEMBL
  A6I638 ENTREZGENE, UniProtKB/TrEMBL
  D3ZU42 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-07 Crebzf  CREB/ATF bZIP transcription factor  RGD1565584  similar to tyrosine kinase-associated leucine zipper protein LAZipII  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565584  similar to tyrosine kinase-associated leucine zipper protein LAZipII   RGD1565584_predicted  similar to tyrosine kinase-associated leucine zipper protein LAZipII (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565584_predicted  similar to tyrosine kinase-associated leucine zipper protein LAZipII (predicted)  LOC293112  similar to tyrosine kinase-associated leucine zipper protein LAZipII  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC293112  similar to tyrosine kinase-associated leucine zipper protein LAZipII      Symbol and Name status set to provisional 70820 PROVISIONAL