Anks1b (ankyrin repeat and sterile alpha motif domain containing 1B) - Rat Genome Database

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Gene: Anks1b (ankyrin repeat and sterile alpha motif domain containing 1B) Rattus norvegicus
Analyze
Symbol: Anks1b
Name: ankyrin repeat and sterile alpha motif domain containing 1B
RGD ID: 1565556
Description: Predicted to enable ephrin receptor binding activity. Involved in postsynapse to nucleus signaling pathway. Acts upstream of or within receptor localization to synapse. Is active in several cellular components, including hippocampal mossy fiber to CA3 synapse; postsynaptic density, intracellular component; and presynaptic cytosol. Orthologous to human ANKS1B (ankyrin repeat and sterile alpha motif domain containing 1B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AIDA-1; amyloid-beta protein intracellular domain-associated protein 1; Ankyrin repeat and sterile alpha motif domain-containing protein 1B; E2A-PBX1-associated protein; EB-1; LOC314721; RGD1565556; similar to cajalin 2 isoform a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8726,200,649 - 27,366,552 (+)NCBIGRCr8
GRCr8 Ensembl726,201,240 - 27,364,943 (+)EnsemblGRCr8 Ensembl
mRatBN7.2724,313,339 - 25,479,307 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl724,312,843 - 25,477,693 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx726,308,631 - 27,472,150 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0728,470,984 - 29,634,542 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0728,248,382 - 29,411,942 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0730,507,135 - 31,684,604 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl730,699,476 - 31,681,182 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0730,603,416 - 31,776,175 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4726,749,708 - 27,914,155 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera721,458,045 - 22,603,947 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
D-glucose  (ISO)
DDE  (ISO)
DDT  (EXP)
diarsenic trioxide  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
fenamidone  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
glucose  (ISO)
ivermectin  (ISO)
maneb  (ISO)
methamphetamine  (ISO)
methoxychlor  (EXP)
N,N-diethyl-m-toluamide  (EXP)
nitrofen  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paraquat  (ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
potassium dichromate  (ISO)
rifampicin  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
temozolomide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triclosan  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Organization of amyloid-beta protein precursor intracellular domain-associated protein-1 in the rat brain. Jacob AL, etal., J Comp Neurol. 2010 Aug 15;518(16):3221-36. doi: 10.1002/cne.22394.
3. Activity-dependent AIDA-1 nuclear signaling regulates nucleolar numbers and protein synthesis in neurons. Jordan BA, etal., Nat Neurosci. 2007 Apr;10(4):427-35. doi: 10.1038/nn1867. Epub 2007 Mar 4.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization. Tindi JO, etal., J Neurosci. 2015 Jun 17;35(24):8986-96. doi: 10.1523/JNEUROSCI.4029-14.2015.
Additional References at PubMed
PMID:15057822   PMID:15169875   PMID:17875921   PMID:22871113   PMID:24746365   PMID:26356309   PMID:27477489   PMID:29476059  


Genomics

Comparative Map Data
Anks1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8726,200,649 - 27,366,552 (+)NCBIGRCr8
GRCr8 Ensembl726,201,240 - 27,364,943 (+)EnsemblGRCr8 Ensembl
mRatBN7.2724,313,339 - 25,479,307 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl724,312,843 - 25,477,693 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx726,308,631 - 27,472,150 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0728,470,984 - 29,634,542 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0728,248,382 - 29,411,942 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0730,507,135 - 31,684,604 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl730,699,476 - 31,681,182 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0730,603,416 - 31,776,175 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4726,749,708 - 27,914,155 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera721,458,045 - 22,603,947 (+)NCBICelera
Cytogenetic Map7q13NCBI
ANKS1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381298,734,786 - 99,984,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1298,726,457 - 99,984,936 (-)EnsemblGRCh38hg38GRCh38
GRCh371299,128,564 - 100,378,714 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361297,653,202 - 98,902,563 (-)NCBINCBI36Build 36hg18NCBI36
Celera1298,793,966 - 100,043,704 (-)NCBICelera
Cytogenetic Map12q23.1NCBI
HuRef1296,189,664 - 97,280,648 (-)NCBIHuRef
CHM1_11299,093,509 - 100,344,110 (-)NCBICHM1_1
T2T-CHM13v2.01298,707,730 - 99,946,157 (-)NCBIT2T-CHM13v2.0
Anks1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391089,707,238 - 90,809,162 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1089,709,371 - 90,809,162 (+)EnsemblGRCm39 Ensembl
GRCm381089,872,915 - 90,973,300 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1089,873,509 - 90,973,300 (+)EnsemblGRCm38mm10GRCm38
MGSCv371089,336,254 - 90,435,730 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361089,302,828 - 90,403,103 (+)NCBIMGSCv36mm8
Celera1091,877,745 - 92,966,422 (+)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1045.28NCBI
Anks1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540534,700,551 - 35,775,960 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540534,701,613 - 35,776,076 (-)NCBIChiLan1.0ChiLan1.0
ANKS1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210106,792,125 - 108,043,418 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112106,791,492 - 108,039,804 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01296,313,293 - 97,559,597 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11299,736,914 - 100,968,737 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1299,737,252 - 100,968,475 (-)Ensemblpanpan1.1panPan2
ANKS1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11538,128,114 - 39,186,341 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1538,129,140 - 39,186,399 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1538,508,921 - 39,565,304 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01538,790,754 - 39,848,495 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1538,790,769 - 39,235,662 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11538,062,386 - 39,106,374 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01538,155,275 - 39,212,769 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01538,428,996 - 39,486,471 (-)NCBIUU_Cfam_GSD_1.0
Anks1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494520,743,191 - 21,793,888 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649213,753,824 - 14,803,766 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649213,753,605 - 14,805,539 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKS1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl584,080,669 - 85,148,976 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1584,080,505 - 85,148,742 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ANKS1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11194,027,310 - 95,286,415 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037149,760,322 - 151,036,204 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Anks1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247507,871,788 - 8,827,745 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247507,871,694 - 8,829,475 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Anks1b
7498 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:224
Count of miRNA genes:77
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000038488, ENSRNOT00000038501, ENSRNOT00000052319, ENSRNOT00000059269
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)72154197751639954Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)72154197751639954Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)72154197735707405Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72092049437412865Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
D7Rat47  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,223,289 - 25,223,463 (+)MAPPERmRatBN7.2
Rnor_6.0731,427,655 - 31,427,828NCBIRnor6.0
Rnor_5.0731,518,951 - 31,519,124UniSTSRnor5.0
RGSC_v3.4727,660,931 - 27,661,104RGDRGSC3.4
RGSC_v3.4727,660,932 - 27,661,105UniSTSRGSC3.4
RGSC_v3.1727,681,202 - 27,681,375RGD
RH 3.4 Map7148.5RGD
RH 3.4 Map7148.5UniSTS
RH 2.0 Map7141.7RGD
FHH x ACI Map77.4699RGD
Cytogenetic Map7q13UniSTS
D7Rat194  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,438,526 - 25,438,669 (+)MAPPERmRatBN7.2
Rnor_6.0731,642,803 - 31,642,945NCBIRnor6.0
Rnor_5.0731,734,050 - 31,734,192UniSTSRnor5.0
RGSC_v3.4727,877,351 - 27,877,494RGDRGSC3.4
RGSC_v3.4727,877,352 - 27,877,494UniSTSRGSC3.4
Celera722,565,821 - 22,565,963UniSTS
RGSC_v3.1727,897,622 - 27,897,765RGD
FHH x ACI Map77.4699RGD
FHH x ACI Map77.4699UniSTS
Cytogenetic Map7q13UniSTS
D7Got16  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2724,710,577 - 24,710,736 (+)MAPPERmRatBN7.2
mRatBN7.2724,710,335 - 24,710,736 (+)MAPPERmRatBN7.2
Rnor_6.0730,904,249 - 30,904,405NCBIRnor6.0
Rnor_6.0730,903,969 - 30,904,405NCBIRnor6.0
Rnor_5.0731,001,487 - 31,001,643UniSTSRnor5.0
Rnor_5.0731,001,207 - 31,001,643UniSTSRnor5.0
RGSC_v3.4727,153,505 - 27,153,661UniSTSRGSC3.4
RGSC_v3.4727,153,504 - 27,153,661RGDRGSC3.4
Celera721,842,997 - 21,843,167UniSTS
RGSC_v3.1727,173,776 - 27,173,932RGD
RH 3.4 Map7141.3UniSTS
RH 3.4 Map7141.3RGD
RH 2.0 Map7142.1RGD
Cytogenetic Map7q13UniSTS
BE102489  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,216,031 - 25,216,190 (+)MAPPERmRatBN7.2
Rnor_6.0731,409,056 - 31,409,214NCBIRnor6.0
Rnor_5.0731,503,629 - 31,503,787UniSTSRnor5.0
RGSC_v3.4727,653,844 - 27,654,002UniSTSRGSC3.4
Celera722,343,404 - 22,343,562UniSTS
RH 3.4 Map7147.1UniSTS
Cytogenetic Map7q13UniSTS
RH138629  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,041,107 - 25,041,256 (+)MAPPERmRatBN7.2
Rnor_6.0731,232,859 - 31,233,007NCBIRnor6.0
Rnor_5.0731,327,432 - 31,327,580UniSTSRnor5.0
RGSC_v3.4727,474,547 - 27,474,695UniSTSRGSC3.4
Celera722,167,250 - 22,167,398UniSTS
RH 3.4 Map7143.8UniSTS
Cytogenetic Map7q13UniSTS
RH144012  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,475,417 - 25,475,517 (+)MAPPERmRatBN7.2
Rnor_6.0731,680,715 - 31,680,814NCBIRnor6.0
Rnor_5.0731,772,291 - 31,772,390UniSTSRnor5.0
RGSC_v3.4727,913,782 - 27,913,881UniSTSRGSC3.4
Celera722,601,672 - 22,601,771UniSTS
RH 3.4 Map7153.9UniSTS
Cytogenetic Map7q13UniSTS
RH144380  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2724,314,731 - 24,314,902 (+)MAPPERmRatBN7.2
Rnor_6.0730,507,738 - 30,507,908NCBIRnor6.0
Rnor_5.0730,604,019 - 30,604,189UniSTSRnor5.0
RGSC_v3.4726,750,311 - 26,750,481UniSTSRGSC3.4
Celera721,458,648 - 21,458,818UniSTS
RH 3.4 Map7144.5UniSTS
Cytogenetic Map7q13UniSTS
RH144500  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,456,657 - 25,456,774 (+)MAPPERmRatBN7.2
Rnor_6.0731,660,932 - 31,661,048NCBIRnor6.0
Rnor_5.0731,752,179 - 31,752,295UniSTSRnor5.0
RGSC_v3.4727,895,481 - 27,895,597UniSTSRGSC3.4
Celera722,584,008 - 22,584,124UniSTS
RH 3.4 Map7152.6UniSTS
Cytogenetic Map7q13UniSTS
BF387129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,218,766 - 25,218,917 (+)MAPPERmRatBN7.2
Rnor_6.0731,411,790 - 31,411,940NCBIRnor6.0
Rnor_5.0731,506,363 - 31,506,513UniSTSRnor5.0
RGSC_v3.4727,656,578 - 27,656,728UniSTSRGSC3.4
Celera722,346,133 - 22,346,283UniSTS
RH 3.4 Map7148.6UniSTS
Cytogenetic Map7q13UniSTS
BF387391  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,222,358 - 25,222,551 (+)MAPPERmRatBN7.2
Rnor_6.0731,426,724 - 31,426,916NCBIRnor6.0
Rnor_5.0731,518,020 - 31,518,212UniSTSRnor5.0
RGSC_v3.4727,660,001 - 27,660,193UniSTSRGSC3.4
Celera722,349,725 - 22,349,917UniSTS
RH 3.4 Map7153.01UniSTS
Cytogenetic Map7q13UniSTS
BE102988  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,236,543 - 25,236,736 (+)MAPPERmRatBN7.2
Rnor_6.0731,439,931 - 31,440,123NCBIRnor6.0
Rnor_5.0731,531,227 - 31,531,419UniSTSRnor5.0
RGSC_v3.4727,674,185 - 27,674,377UniSTSRGSC3.4
Celera722,363,968 - 22,364,160UniSTS
RH 3.4 Map7147.4UniSTS
Cytogenetic Map7q13UniSTS
BE097681  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,226,782 - 25,226,965 (+)MAPPERmRatBN7.2
Rnor_6.0731,431,149 - 31,431,331NCBIRnor6.0
Rnor_6.0731,418,492 - 31,418,674NCBIRnor6.0
Rnor_5.0731,522,445 - 31,522,627UniSTSRnor5.0
Rnor_5.0731,513,065 - 31,513,247UniSTSRnor5.0
RGSC_v3.4727,664,426 - 27,664,608UniSTSRGSC3.4
Celera722,354,164 - 22,354,346UniSTS
RH 3.4 Map7145.2UniSTS
Cytogenetic Map7q13UniSTS
BF401678  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,275,488 - 25,275,669 (+)MAPPERmRatBN7.2
Rnor_6.0731,478,858 - 31,479,038NCBIRnor6.0
Rnor_5.0731,570,154 - 31,570,334UniSTSRnor5.0
RGSC_v3.4727,713,121 - 27,713,301UniSTSRGSC3.4
Celera722,402,903 - 22,403,083UniSTS
RH 3.4 Map7152.3UniSTS
Cytogenetic Map7q13UniSTS
BF403875  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,304,898 - 25,305,108 (+)MAPPERmRatBN7.2
Rnor_6.0731,508,324 - 31,508,533NCBIRnor6.0
Rnor_5.0731,599,571 - 31,599,780UniSTSRnor5.0
RGSC_v3.4727,743,732 - 27,743,941UniSTSRGSC3.4
Celera722,432,084 - 22,432,293UniSTS
Cytogenetic Map7q13UniSTS
RH136686  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,476,740 - 25,476,923 (+)MAPPERmRatBN7.2
Rnor_6.0731,682,038 - 31,682,220NCBIRnor6.0
Rnor_5.0731,773,614 - 31,773,796UniSTSRnor5.0
RGSC_v3.4727,915,105 - 27,915,287UniSTSRGSC3.4
Celera722,602,995 - 22,603,177UniSTS
RH 3.4 Map7176.0UniSTS
Cytogenetic Map7q13UniSTS
AW533069  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,226,222 - 25,226,430 (+)MAPPERmRatBN7.2
Rnor_6.0731,430,587 - 31,430,794NCBIRnor6.0
Rnor_5.0731,521,883 - 31,522,090UniSTSRnor5.0
RGSC_v3.4727,663,864 - 27,664,071UniSTSRGSC3.4
Celera722,353,511 - 22,353,718UniSTS
RH 3.4 Map7148.4UniSTS
Cytogenetic Map7q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 8 34 112 52 52 21 24 21 6 160 77 10 93 45 60 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide DY315019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000059269   ⟹   ENSRNOP00000056036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl726,201,240 - 27,364,136 (+)Ensembl
mRatBN7.2 Ensembl724,313,333 - 25,476,889 (+)Ensembl
Rnor_6.0 Ensembl730,699,476 - 31,681,182 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102313   ⟹   ENSRNOP00000084534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl726,201,240 - 27,364,943 (+)Ensembl
mRatBN7.2 Ensembl724,312,843 - 25,477,693 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113343   ⟹   ENSRNOP00000083101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl726,959,640 - 27,364,136 (+)Ensembl
mRatBN7.2 Ensembl725,072,360 - 25,476,889 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114777   ⟹   ENSRNOP00000078170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl726,201,240 - 27,361,036 (+)Ensembl
mRatBN7.2 Ensembl725,001,474 - 25,472,983 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117411   ⟹   ENSRNOP00000089631
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl726,960,018 - 27,364,943 (+)Ensembl
mRatBN7.2 Ensembl725,072,579 - 25,477,693 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119672   ⟹   ENSRNOP00000083437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl727,220,626 - 27,364,943 (+)Ensembl
mRatBN7.2 Ensembl725,072,579 - 25,477,693 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000150575   ⟹   ENSRNOP00000108068
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl726,201,240 - 27,364,943 (+)Ensembl
RefSeq Acc Id: NM_001271371   ⟹   NP_001258300
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,649 - 27,366,550 (+)NCBI
mRatBN7.2724,313,339 - 25,479,300 (+)NCBI
Rnor_6.0730,507,135 - 31,682,990 (+)NCBI
Rnor_5.0730,603,416 - 31,776,175 (+)NCBI
Celera721,458,045 - 22,603,947 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001414940   ⟹   NP_001401869
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,649 - 27,366,550 (+)NCBI
mRatBN7.2724,313,339 - 25,479,300 (+)NCBI
RefSeq Acc Id: XM_008765241   ⟹   XP_008763463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,679 - 27,366,552 (+)NCBI
mRatBN7.2724,313,810 - 25,479,307 (+)NCBI
Rnor_6.0730,714,324 - 31,684,604 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594828   ⟹   XP_017450317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,682 - 27,366,552 (+)NCBI
mRatBN7.2724,313,810 - 25,479,307 (+)NCBI
Rnor_6.0730,714,326 - 31,684,604 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594830   ⟹   XP_017450319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,680 - 27,366,552 (+)NCBI
mRatBN7.2724,313,810 - 25,479,307 (+)NCBI
Rnor_6.0730,714,324 - 31,684,604 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594832   ⟹   XP_017450321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,679 - 27,360,290 (+)NCBI
mRatBN7.2724,313,810 - 25,475,078 (+)NCBI
Rnor_6.0730,714,323 - 31,678,337 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594833   ⟹   XP_017450322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,679 - 27,366,552 (+)NCBI
mRatBN7.2724,313,810 - 25,479,307 (+)NCBI
Rnor_6.0730,714,323 - 31,681,176 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079046   ⟹   XP_038934974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,681 - 27,366,552 (+)NCBI
mRatBN7.2724,313,810 - 25,479,307 (+)NCBI
RefSeq Acc Id: XM_039079047   ⟹   XP_038934975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,681 - 27,366,552 (+)NCBI
mRatBN7.2724,313,810 - 25,479,307 (+)NCBI
RefSeq Acc Id: XM_039079048   ⟹   XP_038934976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,681 - 27,366,552 (+)NCBI
mRatBN7.2724,313,810 - 25,479,307 (+)NCBI
RefSeq Acc Id: XM_039079050   ⟹   XP_038934978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,677 - 27,366,552 (+)NCBI
mRatBN7.2724,313,810 - 25,479,307 (+)NCBI
RefSeq Acc Id: XM_039079051   ⟹   XP_038934979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,660 - 27,002,115 (+)NCBI
mRatBN7.2724,313,810 - 25,114,740 (+)NCBI
RefSeq Acc Id: XM_063263440   ⟹   XP_063119510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,683 - 27,366,552 (+)NCBI
RefSeq Acc Id: XM_063263441   ⟹   XP_063119511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,680 - 27,360,290 (+)NCBI
RefSeq Acc Id: XM_063263442   ⟹   XP_063119512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,200,668 - 27,332,958 (+)NCBI
RefSeq Acc Id: XM_063263443   ⟹   XP_063119513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8726,959,907 - 27,366,552 (+)NCBI
RefSeq Acc Id: NP_001258300   ⟸   NM_001271371
- Peptide Label: isoform 2
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008763463   ⟸   XM_008765241
- Peptide Label: isoform X10
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017450322   ⟸   XM_017594833
- Peptide Label: isoform X7
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017450321   ⟸   XM_017594832
- Peptide Label: isoform X5
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017450319   ⟸   XM_017594830
- Peptide Label: isoform X2
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017450317   ⟸   XM_017594828
- Peptide Label: isoform X1
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000056036   ⟸   ENSRNOT00000059269
RefSeq Acc Id: XP_038934974   ⟸   XM_039079046
- Peptide Label: isoform X3
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038934975   ⟸   XM_039079047
- Peptide Label: isoform X6
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038934976   ⟸   XM_039079048
- Peptide Label: isoform X9
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038934978   ⟸   XM_039079050
- Peptide Label: isoform X12
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038934979   ⟸   XM_039079051
- Peptide Label: isoform X13
Ensembl Acc Id: ENSRNOP00000083101   ⟸   ENSRNOT00000113343
Ensembl Acc Id: ENSRNOP00000083437   ⟸   ENSRNOT00000119672
Ensembl Acc Id: ENSRNOP00000089631   ⟸   ENSRNOT00000117411
Ensembl Acc Id: ENSRNOP00000078170   ⟸   ENSRNOT00000114777
Ensembl Acc Id: ENSRNOP00000084534   ⟸   ENSRNOT00000102313
RefSeq Acc Id: NP_001401869   ⟸   NM_001414940
- Peptide Label: isoform 1
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot),   A0A8I6GAL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119512   ⟸   XM_063263442
- Peptide Label: isoform X11
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063119511   ⟸   XM_063263441
- Peptide Label: isoform X8
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063119510   ⟸   XM_063263440
- Peptide Label: isoform X4
- UniProtKB: P0C6S7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063119513   ⟸   XM_063263443
- Peptide Label: isoform X14
- UniProtKB: A0A8I5Y9Y6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108068   ⟸   ENSRNOT00000150575
Protein Domains
PID   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C6S7-F1-model_v2 AlphaFold P0C6S7 1-1260 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565556 AgrOrtholog
BioCyc Gene G2FUF-34484 BioCyc
Ensembl Genes ENSRNOG00000024870 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000059269 ENTREZGENE
  ENSRNOT00000102313 ENTREZGENE
  ENSRNOT00000114777 ENTREZGENE
  ENSRNOT00000119672.1 UniProtKB/Swiss-Prot
  ENSRNOT00000150575 ENTREZGENE
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  1.25.40.20 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
InterPro ANKS1/Caskin UniProtKB/Swiss-Prot
  Ankyrin_rpt UniProtKB/Swiss-Prot
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  PTB/PI_dom UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
  SAM_ANKS1_repeat1 UniProtKB/Swiss-Prot
  SAM_ANKS1_repeat2 UniProtKB/Swiss-Prot
NCBI Gene 314721 ENTREZGENE
PANTHER ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot
  PTHR24174:SF3 UniProtKB/Swiss-Prot
Pfam Ank_2 UniProtKB/Swiss-Prot
  PID UniProtKB/Swiss-Prot
  SAM_1 UniProtKB/Swiss-Prot
PhenoGen Anks1b PhenoGen
PRINTS ANKYRIN UniProtKB/Swiss-Prot
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot
  PID UniProtKB/Swiss-Prot
  SAM_DOMAIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000024870 RatGTEx
SMART ANK UniProtKB/Swiss-Prot
  PTB UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF47769 UniProtKB/Swiss-Prot
  SSF48403 UniProtKB/Swiss-Prot
UniProt A0A8I5Y9Y6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7P8_RAT UniProtKB/TrEMBL
  A0A8I6GAB9_RAT UniProtKB/TrEMBL
  A0A8I6GAL6 ENTREZGENE, UniProtKB/TrEMBL
  ANS1B_RAT UniProtKB/Swiss-Prot
  F1M2J2_RAT UniProtKB/TrEMBL
  P0C6S7 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-02 Anks1b  ankyrin repeat and sterile alpha motif domain containing 1B   RGD1565556  similar to cajalin 2 isoform a   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565556  similar to cajalin 2 isoform a   RGD1565556_predicted  similar to cajalin 2 isoform a (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565556_predicted  similar to cajalin 2 isoform a (predicted)  LOC314721  similar to cajalin 2 isoform a  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC314721  similar to cajalin 2 isoform a      Symbol and Name status set to provisional 70820 PROVISIONAL