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Gene: Glis3 (GLIS family zinc finger 3) Rattus norvegicus
Symbol: Glis3
Name: GLIS family zinc finger 3
RGD ID: 1565505
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription factor binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in neonatal diabetes mellitus with congenital hypothyroidism. Orthologous to human GLIS3 (GLIS family zinc finger 3); INTERACTS WITH 1-naphthyl isothiocyanate; glyphosate; (-)-epigallocatechin 3-gallate (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: hypothetical protein LOC680671; hypothetical protein LOC687614; LOC293882; LOC680671; RGD1565505; similar to Zinc finger protein GLIS3 (GLI-similar 3); zinc finger protein GLIS3
Homo sapiens (human) : GLIS3 (GLIS family zinc finger 3)  HGNC  Alliance
Mus musculus (house mouse) : Glis3 (GLIS family zinc finger 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glis3 (GLIS family zinc finger 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GLIS3 (GLIS family zinc finger 3)
Canis lupus familiaris (dog) : GLIS3 (GLIS family zinc finger 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glis3 (GLIS family zinc finger 3)
Sus scrofa (pig) : GLIS3 (GLIS family zinc finger 3)
Chlorocebus sabaeus (African green monkey) : GLIS3 (GLIS family zinc finger 3)
Heterocephalus glaber (naked mole-rat) : Glis3 (GLIS family zinc finger 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01246,380,816 - 246,564,385 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1246,380,889 - 246,785,360 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01253,622,178 - 254,039,761 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,291,906 - 232,306,168 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.41231,881,983 - 232,292,288 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1223,130,737 - 223,177,831 (-)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Glis3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1565505
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.