Itih2 (inter-alpha-trypsin inhibitor heavy chain 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Itih2 (inter-alpha-trypsin inhibitor heavy chain 2) Rattus norvegicus
Analyze
Symbol: Itih2
Name: inter-alpha-trypsin inhibitor heavy chain 2
RGD ID: 1565426
Description: Predicted to enable hyaluronic acid binding activity. Predicted to be involved in hyaluronan metabolic process. Predicted to be located in extracellular region. Orthologous to human ITIH2 (inter-alpha-trypsin inhibitor heavy chain 2); INTERACTS WITH 17beta-estradiol; cobalt dichloride; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: inter-alpha-trypsin inhibitor heavy chain H2; LOC498793; similar to inter-alpha-inhibitor H2 chain
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81773,285,281 - 73,321,555 (+)NCBIGRCr8
mRatBN7.21768,375,574 - 68,411,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1768,375,567 - 68,411,841 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01772,160,734 - 72,197,248 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1772,160,735 - 72,195,509 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01773,846,130 - 73,882,952 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41779,688,702 - 79,726,869 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1767,862,012 - 67,898,344 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucose  (ISO)
amiodarone  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
caffeine  (ISO)
calcium atom  (ISO)
calcium dichloride  (ISO)
calcium(0)  (ISO)
chloroprene  (ISO)
clofibrate  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cyproconazole  (ISO)
D-glucose  (ISO)
Dibutyl phosphate  (ISO)
diquat  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
fipronil  (EXP)
flutamide  (EXP)
fructose  (ISO)
glucose  (ISO)
glycidol  (EXP)
hydrazine  (ISO)
hydroxyurea  (ISO)
inulin  (ISO)
magnesium atom  (ISO)
magnesium dichloride  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methoxychlor  (EXP)
N-nitrosodiethylamine  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
olanzapine  (ISO)
ozone  (ISO)
p-anisidine  (ISO)
p-toluidine  (EXP)
paclitaxel  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
propanal  (ISO)
propiconazole  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP,ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:20458337   PMID:22516433   PMID:23533145   PMID:24006456  


Genomics

Comparative Map Data
Itih2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81773,285,281 - 73,321,555 (+)NCBIGRCr8
mRatBN7.21768,375,574 - 68,411,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1768,375,567 - 68,411,841 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01772,160,734 - 72,197,248 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1772,160,735 - 72,195,509 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01773,846,130 - 73,882,952 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41779,688,702 - 79,726,869 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1767,862,012 - 67,898,344 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
ITIH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38107,703,316 - 7,749,520 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl107,703,316 - 7,749,520 (+)EnsemblGRCh38hg38GRCh38
GRCh37107,745,279 - 7,791,483 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36107,785,242 - 7,831,489 (+)NCBINCBI36Build 36hg18NCBI36
Build 34107,785,342 - 7,831,488NCBI
Celera107,671,050 - 7,717,293 (+)NCBICelera
Cytogenetic Map10p14NCBI
HuRef107,663,584 - 7,709,831 (+)NCBIHuRef
CHM1_1107,745,665 - 7,791,444 (+)NCBICHM1_1
T2T-CHM13v2.0107,703,948 - 7,750,283 (+)NCBIT2T-CHM13v2.0
Itih2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39210,099,408 - 10,135,492 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl210,099,404 - 10,136,207 (-)EnsemblGRCm39 Ensembl
GRCm38210,094,591 - 10,130,683 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl210,094,593 - 10,131,396 (-)EnsemblGRCm38mm10GRCm38
MGSCv37210,016,218 - 10,052,310 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36210,012,444 - 10,048,517 (-)NCBIMGSCv36mm8
Celera210,033,646 - 10,069,833 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map26.89NCBI
Itih2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542124,150,526 - 24,189,810 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542124,149,081 - 24,189,810 (+)NCBIChiLan1.0ChiLan1.0
ITIH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2820,251,216 - 20,300,738 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11020,256,543 - 20,306,869 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0107,732,931 - 7,782,362 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1107,713,517 - 7,762,756 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl107,713,454 - 7,762,756 (+)Ensemblpanpan1.1panPan2
ITIH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1228,367,842 - 28,403,610 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl228,367,908 - 28,403,667 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha225,408,695 - 25,444,418 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0228,749,446 - 28,785,349 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl228,749,543 - 28,785,325 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1225,855,861 - 25,891,725 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0226,697,790 - 26,733,520 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0227,415,891 - 27,451,788 (-)NCBIUU_Cfam_GSD_1.0
Itih2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934430,900,059 - 30,936,820 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364847,065,406 - 7,101,855 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364847,064,836 - 7,101,872 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITIH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1063,635,210 - 63,672,163 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11063,635,206 - 63,672,200 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21069,732,423 - 69,752,000 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITIH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.197,748,818 - 7,794,932 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl97,749,464 - 7,794,933 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605113,144,753 - 13,190,763 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itih2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247752,667,781 - 2,707,046 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247752,667,840 - 2,706,951 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Itih2
287 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:89
Count of miRNA genes:76
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000038817
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)175724672370156904Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)175724672370852846Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176364000973951021Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat

Markers in Region
D17Got89  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21768,380,268 - 68,380,486 (+)MAPPERmRatBN7.2
Rnor_6.01772,166,081 - 72,166,298NCBIRnor6.0
Rnor_5.01773,851,470 - 73,851,687UniSTSRnor5.0
RGSC_v3.41779,695,097 - 79,695,315RGDRGSC3.4
RGSC_v3.41779,695,098 - 79,695,315UniSTSRGSC3.4
RGSC_v3.11779,705,931 - 79,706,148RGD
Celera1767,866,764 - 67,866,981UniSTS
RH 3.4 Map17649.2UniSTS
RH 3.4 Map17649.2RGD
RH 2.0 Map17593.2RGD
Cytogenetic Map17q12.3UniSTS
RH139079  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21768,375,573 - 68,375,718 (+)MAPPERmRatBN7.2
Rnor_6.01772,160,797 - 72,160,941NCBIRnor6.0
Rnor_5.01773,846,186 - 73,846,330UniSTSRnor5.0
RGSC_v3.41779,689,919 - 79,690,063UniSTSRGSC3.4
Celera1767,862,070 - 67,862,214UniSTS
RH 3.4 Map17657.0UniSTS
Cytogenetic Map17q12.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 24 24 24
Medium 126 123 123 3
Low 8 33 15 17 15 29 34 95 19 15
Below cutoff 13 74 44 39 19 20 139 53 35 25 9

Sequence


Ensembl Acc Id: ENSRNOT00000038817   ⟹   ENSRNOP00000036443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1768,375,567 - 68,409,899 (+)Ensembl
Rnor_6.0 Ensembl1772,160,735 - 72,195,509 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107455   ⟹   ENSRNOP00000088103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1768,375,567 - 68,410,659 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120221   ⟹   ENSRNOP00000082662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1768,375,567 - 68,411,841 (+)Ensembl
RefSeq Acc Id: NM_001419801   ⟹   NP_001406730
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81773,285,281 - 73,321,555 (+)NCBI
mRatBN7.21768,375,574 - 68,411,849 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001406730 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00088 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000036443.7
  ENSRNOP00000082662.1
  ENSRNOP00000088103.1
Ensembl Acc Id: ENSRNOP00000036443   ⟸   ENSRNOT00000038817
Ensembl Acc Id: ENSRNOP00000082662   ⟸   ENSRNOT00000120221
Ensembl Acc Id: ENSRNOP00000088103   ⟸   ENSRNOT00000107455
RefSeq Acc Id: NP_001406730   ⟸   NM_001419801
- Peptide Label: precursor
- UniProtKB: A0A8I5ZVC4 (UniProtKB/TrEMBL)
Protein Domains
VIT   VWFA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZFH5-F1-model_v2 AlphaFold D3ZFH5 1-826 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700565
Promoter ID:EPDNEW_R11082
Type:initiation region
Name:Itih2_1
Description:inter-alpha-trypsin inhibitor heavy chain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01772,160,797 - 72,160,857EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565426 AgrOrtholog
BioCyc Gene G2FUF-8757 BioCyc
Ensembl Genes ENSRNOG00000001066 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038817.7 UniProtKB/TrEMBL
  ENSRNOT00000107455.1 UniProtKB/TrEMBL
  ENSRNOT00000120221.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7370417 IMAGE-MGC_LOAD
InterPro ITI_HC_C UniProtKB/TrEMBL
  ITIH UniProtKB/TrEMBL
  VIT UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
MGC_CLONE MGC:112781 IMAGE-MGC_LOAD
NCBI Gene Itih2 ENTREZGENE
PANTHER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER UniProtKB/TrEMBL
  INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H2 UniProtKB/TrEMBL
Pfam ITI_HC_C UniProtKB/TrEMBL
  VIT UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
PhenoGen Itih2 PhenoGen
PROSITE VIT UniProtKB/TrEMBL
  VWFA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001066 RatGTEx
SMART VIT UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
UniProt A0A8I5ZVC4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7A2_RAT UniProtKB/TrEMBL
  D3ZFH5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-09 Itih2  inter-alpha-trypsin inhibitor heavy chain 2  LOC498793  similar to inter-alpha-inhibitor H2 chain  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC498793  similar to inter-alpha-inhibitor H2 chain      Symbol and Name status set to provisional 70820 PROVISIONAL