Ifitm3-ps1 (interferon induced transmembrane protein 3, pseudogene 1) - Rat Genome Database

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Gene: Ifitm3-ps1 (interferon induced transmembrane protein 3, pseudogene 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ifitm3-ps1
Name: interferon induced transmembrane protein 3, pseudogene 1 (Ensembl:interferon induced transmembrane protein3, pseudogene 1)
RGD ID: 1565332
Description: Predicted to be involved in several processes, including defense response to other organism; negative regulation of viral genome replication; and response to interferon-alpha. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human IFITM3 (interferon induced transmembrane protein 3); INTERACTS WITH 17alpha-ethynylestradiol; N-methyl-4-phenylpyridinium.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: AABR07015596.1; interferon induced transmembrane protein3, pseudogene 1; LOC289685; RGD1565332; similar to interferon induced transmembrane protein 3
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81465,445,869 - 65,446,288 (-)NCBIGRCr8
mRatBN7.21461,233,269 - 61,233,688 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1461,233,269 - 61,233,688 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01465,152,594 - 65,153,013 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1465,152,594 - 65,153,013 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01465,237,185 - 65,237,604 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41466,133,358 - 66,133,777 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1460,302,268 - 60,302,687 (-)NCBICelera
Cytogenetic Map14q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142216796767167967Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
GenBank Nucleotide JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000071542   ⟹   ENSRNOP00000072368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1461,233,269 - 61,233,688 (-)Ensembl
Protein Sequences
Ensembl Protein ENSRNOP00000072368.1
Ensembl Acc Id: ENSRNOP00000072368   ⟸   ENSRNOT00000071542

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K2T5-F1-model_v2 AlphaFold A0A0G2K2T5 1-139 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565332 AgrOrtholog
BioCyc Gene G2FUF-15573 BioCyc
Ensembl Genes ENSRNOG00000048944 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071542.3 UniProtKB/TrEMBL
InterPro CD225/Dispanin_fam UniProtKB/TrEMBL
  IFITM_antiviral_protein UniProtKB/TrEMBL
NCBI Gene 289685 ENTREZGENE
PANTHER INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN UniProtKB/TrEMBL
  INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3 UniProtKB/TrEMBL
Pfam CD225 UniProtKB/TrEMBL
PhenoGen Ifitm3-ps1 PhenoGen
RatGTEx ENSRNOG00000048944 RatGTEx
UniProt A0A0G2K2T5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-01-24 Ifitm3-ps1  interferon induced transmembrane protein 3, pseudogene 1  Ifitm3-ps1  interferon induced transmembrane protein3, pseudogene 1  Name changed 629549 APPROVED
2022-06-10 Ifitm3-ps1  interferon induced transmembrane protein3, pseudogene 1  RGD1565332  similar to interferon induced transmembrane protein 3  Symbol and Name Changed 1299863 APPROVED
2022-06-02 RGD1565332  similar to interferon induced transmembrane protein 3  AABR07015596.1    Data merged from RGD:15005634 737654 PROVISIONAL
2019-11-08 AABR07015596.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 RGD1565332  similar to interferon induced transmembrane protein 3   RGD1565332_predicted  similar to interferon induced transmembrane protein 3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565332_predicted  similar to interferon induced transmembrane protein 3 (predicted)  LOC289685  similar to interferon induced transmembrane protein 3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC289685  similar to interferon induced transmembrane protein 3      Symbol and Name status set to provisional 70820 PROVISIONAL