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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Shroom2 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Shroom2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SHROOM2 mRNA | CTD | PMID:36331819 | Shroom2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Shroom2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of SHROOM2 mRNA | CTD | PMID:22206623 | Shroom2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Shroom2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SHROOM2 mRNA | CTD | PMID:16214954 | Shroom2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Shroom2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SHROOM2 mRNA | CTD | PMID:21570461 | Shroom2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SHROOM2 mRNA | CTD | PMID:21215274|PMID:32109520 | Shroom2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Shroom2 (Mus musculus) | 6480464 | AHR protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of SHROOM2 mRNA] | CTD | PMID:16214954 | Shroom2 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of SHROOM2 mRNA | CTD | PMID:32109520 | Shroom2 | Rat | 2-palmitoylglycerol | increases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of SHROOM2 mRNA | CTD | PMID:37199045 | Shroom2 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SHROOM2 mRNA | CTD | PMID:23196670 | Shroom2 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Shroom2 (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of SHROOM2 mRNA | CTD | PMID:25172293 | Shroom2 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Shroom2 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Shroom2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of SHROOM2 mRNA | CTD | PMID:28973697 | Shroom2 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SHROOM2 mRNA | CTD | PMID:24780913 | Shroom2 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SHROOM2 mRNA | CTD | PMID:31881176 | Shroom2 | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of SHROOM2 mRNA | CTD | PMID:28959563 | Shroom2 | Rat | afimoxifene | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | afimoxifene inhibits the reaction [Estrogens results in decreased expression of SHROOM2 mRNA] | CTD | PMID:21233418 | Shroom2 | Rat | aflatoxin B1 | increases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of SHROOM2 mRNA | CTD | PMID:21641981 | Shroom2 | Rat | aflatoxin B1 | increases methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SHROOM2 intron | CTD | PMID:30157460 | Shroom2 | Rat | Aflatoxin B2 alpha | increases methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of SHROOM2 intron | CTD | PMID:30157460 | Shroom2 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SHROOM2 mRNA | CTD | PMID:16483693 | Shroom2 | Rat | aristolochic acid A | decreases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SHROOM2 mRNA | CTD | PMID:33212167 | Shroom2 | Rat | arsenite(3-) | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to SHROOM2 mRNA] | CTD | PMID:32406909 | Shroom2 | Rat | benzo[a]pyrene | decreases methylation | ISO | Shroom2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of SHROOM2 intron | CTD | PMID:27901495 | Shroom2 | Rat | benzo[a]pyrene | affects methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SHROOM2 intron; Benzo(a)pyrene affects the methylation of SHROOM2 promoter | CTD | PMID:27901495|PMID:30157460 | Shroom2 | Rat | benzo[a]pyrene | increases methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SHROOM2 exon | CTD | PMID:27901495 | Shroom2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SHROOM2 mRNA | CTD | PMID:20382639 | Shroom2 | Rat | benzo[e]pyrene | increases methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of SHROOM2 intron | CTD | PMID:30157460 | Shroom2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SHROOM2 mRNA | CTD | PMID:25181051 | Shroom2 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Shroom2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SHROOM2 mRNA | CTD | PMID:34947998 | Shroom2 | Rat | bisphenol A | increases expression | ISO | Shroom2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of SHROOM2 mRNA | CTD | PMID:25594700|PMID:33221593 | Shroom2 | Rat | bisphenol F | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of SHROOM2 gene | CTD | PMID:31601247 | Shroom2 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Shroom2 | Rat | cadmium dichloride | increases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of SHROOM2 mRNA | CTD | PMID:38382870 | Shroom2 | Rat | caffeine | affects phosphorylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of SHROOM2 protein | CTD | PMID:35688186 | Shroom2 | Rat | calcitriol | increases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of SHROOM2 mRNA | CTD | PMID:21592394 | Shroom2 | Rat | calcitriol | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of SHROOM2 mRNA | CTD | PMID:21592394 | Shroom2 | Rat | carbon nanotube | increases expression | ISO | Shroom2 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of SHROOM2 mRNA | CTD | PMID:25554681 | Shroom2 | Rat | carbon nanotube | increases methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | Nanotubes, Carbon results in increased methylation of SHROOM2 gene | CTD | PMID:29426343 | Shroom2 | Rat | CGP 52608 | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SHROOM2 gene] | CTD | PMID:28238834 | Shroom2 | Rat | chloroprene | increases expression | ISO | Shroom2 (Mus musculus) | 6480464 | Chloroprene results in increased expression of SHROOM2 mRNA | CTD | PMID:23125180 | Shroom2 | Rat | copper(II) sulfate | decreases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SHROOM2 mRNA | CTD | PMID:19549813 | Shroom2 | Rat | crocidolite asbestos | decreases expression | ISO | Shroom2 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of SHROOM2 mRNA | CTD | PMID:29279043 | Shroom2 | Rat | dicrotophos | increases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of SHROOM2 mRNA | CTD | PMID:28302478 | Shroom2 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of SHROOM2 mRNA | CTD | PMID:29391264 | Shroom2 | Rat | ethanol | affects splicing | ISO | Shroom2 (Mus musculus) | 6480464 | Ethanol affects the splicing of SHROOM2 mRNA | CTD | PMID:30319688 | Shroom2 | Rat | FR900359 | affects phosphorylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of SHROOM2 protein | CTD | PMID:37730182 | Shroom2 | Rat | fulvestrant | increases methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of SHROOM2 gene | CTD | PMID:31601247 | Shroom2 | Rat | fulvestrant | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of SHROOM2 gene | CTD | PMID:31601247 | Shroom2 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SHROOM2 mRNA | CTD | PMID:33387578 | Shroom2 | Rat | inulin | multiple interactions | ISO | Shroom2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SHROOM2 mRNA | CTD | PMID:36331819 | Shroom2 | Rat | isoprenaline | increases expression | ISO | Shroom2 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of SHROOM2 mRNA | CTD | PMID:20003209 | Shroom2 | Rat | ketoconazole | increases expression | EXP | | 6480464 | Ketoconazole results in increased expression of SHROOM2 mRNA | CTD | PMID:36653537 | Shroom2 | Rat | lipopolysaccharide | decreases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of SHROOM2 mRNA | CTD | PMID:35811015 | Shroom2 | Rat | lipopolysaccharide | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of SHROOM2 mRNA; S-(1,2-dichlorovinyl)cysteine promotes the reaction more ... | CTD | PMID:35811015 | Shroom2 | Rat | methapyrilene | increases methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of SHROOM2 intron | CTD | PMID:30157460 | Shroom2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SHROOM2 mRNA | CTD | PMID:33387578 | Shroom2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Shroom2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SHROOM2 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Shroom2 | Rat | pirinixic acid | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Shroom2 | Rat | poly(I:C) | multiple interactions | EXP | | 6480464 | [Poly I-C co-treated with HU 211] results in decreased expression of SHROOM2 mRNA | CTD | PMID:26923065 | Shroom2 | Rat | propanal | increases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of SHROOM2 mRNA | CTD | PMID:26079696 | Shroom2 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of SHROOM2 mRNA; S-(1,2-dichlorovinyl)cysteine promotes the reaction more ... | CTD | PMID:35811015 | Shroom2 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | decreases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | S-(1,2-dichlorovinyl)cysteine results in decreased expression of SHROOM2 mRNA | CTD | PMID:35811015 | Shroom2 | Rat | sevoflurane | decreases expression | ISO | Shroom2 (Mus musculus) | 6480464 | Sevoflurane results in decreased expression of SHROOM2 protein | CTD | PMID:35249202 | Shroom2 | Rat | silicon dioxide | decreases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of SHROOM2 mRNA | CTD | PMID:25895662 | Shroom2 | Rat | sodium arsenite | affects methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of SHROOM2 gene | CTD | PMID:28589171 | Shroom2 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of SHROOM2 mRNA | CTD | PMID:19281266 | Shroom2 | Rat | sunitinib | decreases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of SHROOM2 mRNA | CTD | PMID:31533062 | Shroom2 | Rat | testosterone | multiple interactions | ISO | SHROOM2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of SHROOM2 mRNA | CTD | PMID:21592394 | Shroom2 | Rat | testosterone | increases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Testosterone results in increased expression of SHROOM2 mRNA | CTD | PMID:21592394 | Shroom2 | Rat | tetrachloromethane | increases expression | ISO | Shroom2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of SHROOM2 mRNA | CTD | PMID:17484886 | Shroom2 | Rat | thiram | decreases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Thiram results in decreased expression of SHROOM2 mRNA | CTD | PMID:38568856 | Shroom2 | Rat | titanium dioxide | increases methylation | ISO | Shroom2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of SHROOM2 promoter | CTD | PMID:35295148 | Shroom2 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of SHROOM2 mRNA | CTD | PMID:33387578 | Shroom2 | Rat | triptonide | decreases expression | ISO | Shroom2 (Mus musculus) | 6480464 | triptonide results in decreased expression of SHROOM2 mRNA | CTD | PMID:33045310 | Shroom2 | Rat | troglitazone | decreases expression | ISO | Shroom2 (Mus musculus) | 6480464 | troglitazone results in decreased expression of SHROOM2 mRNA | CTD | PMID:28973697 | Shroom2 | Rat | urethane | increases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Urethane results in increased expression of SHROOM2 mRNA | CTD | PMID:28818685 | Shroom2 | Rat | valproic acid | increases methylation | ISO | SHROOM2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of SHROOM2 gene | CTD | PMID:29154799 | Shroom2 | Rat | valproic acid | increases expression | ISO | SHROOM2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SHROOM2 mRNA | CTD | PMID:19101580 | Shroom2 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of SHROOM2 mRNA | CTD | PMID:23034163 | |