Slc7a3l1 (solute carrier family 7 member 3 like 1) - Rat Genome Database

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Gene: Slc7a3l1 (solute carrier family 7 member 3 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Slc7a3l1
Name: solute carrier family 7 member 3 like 1
RGD ID: 1565097
Description: Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transport. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: PREDICTED
Previously known as: hypothetical protein LOC292543; LOC292543; MGC116223; similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 3; uncharacterized protein LOC292543
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8174,968,538 - 74,982,432 (+)NCBIGRCr8
GRCr8 Ensembl174,961,837 - 74,982,429 (+)EnsemblGRCr8 Ensembl
mRatBN7.2166,053,135 - 66,067,042 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,053,268 - 66,067,039 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx171,500,946 - 71,514,663 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0179,923,920 - 79,937,620 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0173,257,190 - 73,270,886 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0164,618,347 - 64,632,132 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl164,618,506 - 64,632,131 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0163,610,393 - 63,624,069 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4164,378,810 - 64,392,101 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera163,774,569 - 63,788,083 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
8 9 35 55 66 64 34 25 34 6 149 81 35 18 55 30 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000091279   ⟹   ENSRNOP00000071240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl174,961,837 - 74,982,429 (+)Ensembl
mRatBN7.2 Ensembl166,053,268 - 66,067,039 (+)Ensembl
Rnor_6.0 Ensembl164,618,506 - 64,632,131 (+)Ensembl
RefSeq Acc Id: NM_001025639   ⟹   NP_001020810
RefSeq Status: PREDICTED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,968,721 - 74,982,432 (+)NCBI
mRatBN7.2166,053,318 - 66,067,042 (+)NCBI
Rnor_6.0164,618,506 - 64,632,132 (+)NCBI
Rnor_5.0163,610,393 - 63,624,069 (+)NCBI
RGSC_v3.4164,378,810 - 64,392,101 (+)RGD
Celera163,774,569 - 63,788,083 (+)RGD
Sequence:
RefSeq Acc Id: XM_006228022   ⟹   XP_006228084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,968,538 - 74,982,285 (+)NCBI
mRatBN7.2166,053,135 - 66,066,863 (+)NCBI
Rnor_6.0164,618,427 - 64,631,678 (+)NCBI
Rnor_5.0163,610,393 - 63,624,069 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001020810 (Get FASTA)   NCBI Sequence Viewer  
  XP_006228084 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98062 (Get FASTA)   NCBI Sequence Viewer  
  EDL84953 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071240
  ENSRNOP00000071240.2
RefSeq Acc Id: NP_001020810   ⟸   NM_001025639
- UniProtKB: Q4V799 (UniProtKB/TrEMBL),   D3ZBE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228084   ⟸   XM_006228022
- Peptide Label: isoform X1
- UniProtKB: D3ZBE1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071240   ⟸   ENSRNOT00000091279
Protein Domains
Cationic amino acid transporter C-terminal

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565097 AgrOrtholog
BioCyc Gene G2FUF-60990 BioCyc
Ensembl Genes ENSRNOG00000054438 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000091279 ENTREZGENE
  ENSRNOT00000091279.2 UniProtKB/TrEMBL
Gene3D-CATH Amino acid/polyamine transporter I UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7458331 IMAGE-MGC_LOAD
InterPro AA/rel_permease1 UniProtKB/TrEMBL
  Cat_AA_permease UniProtKB/TrEMBL
  CAT_C UniProtKB/TrEMBL
KEGG Report rno:292543 UniProtKB/TrEMBL
MGC_CLONE MGC:116223 IMAGE-MGC_LOAD
NCBI Gene 292543 ENTREZGENE
PANTHER EXPRESSED SEQUENCE AU018091 UniProtKB/TrEMBL
  INNER MEMBRANE TRANSPORTER YGJI-RELATED UniProtKB/TrEMBL
Pfam AA_permease_2 UniProtKB/TrEMBL
  AA_permease_C UniProtKB/TrEMBL
PhenoGen Slc7a3l1 PhenoGen
PIRSF AA_transporter UniProtKB/TrEMBL
RatGTEx ENSRNOG00000054438 RatGTEx
UniProt D3ZBE1 ENTREZGENE, UniProtKB/TrEMBL
  Q4V799 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Slc7a3l1  solute carrier family 7 member 3 like 1  LOC292543  similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 3  Symbol and Name Changed 1299863 APPROVED
2006-02-09 LOC292543  similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 3      Symbol and Name status set to provisional 70820 PROVISIONAL