Retreg1 (reticulophagy regulator 1)

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Gene: Retreg1 (reticulophagy regulator 1) Rattus norvegicus

Analyze

Symbol:

Retreg1 (Ensembl: Zfp622)

Name:

reticulophagy regulator 1 (Ensembl:zinc finger protein 622)

RGD ID:

1565003

Description:

Predicted to enable endoplasmic reticulum-autophagosome adaptor activity and protein self-association. Predicted to be involved in negative regulation of neuron apoptotic process; reticulophagy; and sensory perception of pain. Predicted to act upstream of or within several processes, including collagen catabolic process; mitophagy; and white fat cell differentiation. Predicted to be located in cis-Golgi network; endoplasmic reticulum membrane; and nuclear lumen. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 2B. Orthologous to human RETREG1 (reticulophagy regulator 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Fam134b; family with sequence similarity 134, member B; hypothetical protein LOC619558; LOC103689968; LOC619558; protein FAM134B; reticulophagy receptor 1; reticulophagy receptor FAM134B

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RETREG1 (reticulophagy regulator 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther
Mus musculus (house mouse):	Retreg1 (reticulophagy regulator 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Retreg1 (reticulophagy regulator 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RETREG1 (reticulophagy regulator 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RETREG1 (reticulophagy regulator 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Retreg1 (reticulophagy regulator 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RETREG1 (reticulophagy regulator 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RETREG1 (reticulophagy regulator 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Retreg1 (reticulophagy regulator 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZNF622 (zinc finger protein 622)	HGNC	Ensembl, OrthoDB
Alliance orthologs ³
Homo sapiens (human):	RETREG1 (reticulophagy regulator 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Retreg1 (reticulophagy regulator 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	retreg1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	76,335,609 - 76,474,817 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	76,335,609 - 76,493,898 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	83,455,839 - 83,595,059 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	81,577,567 - 81,716,777 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	76,582,768 - 76,722,071 (+)	NCBI	Rnor_WKY
Rnor_6.0	2	78,391,921 - 78,401,569 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	78,391,921 - 78,399,987 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	2	78,103,387 - 78,276,927 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	97,821,407 - 97,972,821 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	77,470,558 - 77,566,123 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	72,093,456 - 72,182,485 (+)	NCBI		Celera
Cytogenetic Map	2	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease (ISO)

genetic disease (ISO)

hereditary sensory and autonomic neuropathy type 2 (ISO)

hereditary sensory and autonomic neuropathy type 2A (ISO)

hereditary sensory and autonomic neuropathy type 2B (ISO)

hereditary sensory neuropathy (ISO)

hereditary spastic paraplegia (ISO)

Neurodevelopmental Disorders (ISO)

Vesicoureteral Reflux 5 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(2,4,5-trichlorophenoxy)acetic acid (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (EXP)

aldrin (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

buspirone (EXP)

carbamazepine (ISO)

carbon nanotube (ISO)

chloroethene (ISO)

chlorogenic acid (EXP)

cisplatin (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

D-glucose (EXP)

decabromodiphenyl ether (EXP)

dexamethasone (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

fenthion (ISO)

furan (EXP)

gentamycin (EXP)

glafenine (EXP)

glucose (EXP)

glutathione (EXP)

indometacin (ISO)

isotretinoin (ISO)

lead diacetate (EXP)

lead(0) (ISO)

lead(2+) (ISO)

levofloxacin (EXP)

lipopolysaccharide (ISO)

menadione (ISO)

mercury dibromide (ISO)

methapyrilene (EXP)

methylmercury chloride (ISO)

nefazodone (EXP)

nevirapine (EXP)

nickel sulfate (ISO)

O-methyleugenol (ISO)

oxaliplatin (EXP)

paracetamol (ISO)

paraquat (EXP)

parathion (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

progesterone (ISO)

propanal (ISO)

propiconazole (ISO)

raloxifene (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium dichromate (EXP)

tamoxifen (ISO)

temozolomide (ISO)

tetrachloroethene (ISO)

tetrachloromethane (EXP,ISO)

topotecan (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagy (ISO)

collagen catabolic process (ISO)

endoplasmic reticulum organization (ISO)

mitophagy (ISO)

negative regulation of neuron apoptotic process (IBA,ISO,ISS)

reticulophagy (IBA,IEA,ISO,ISS)

ribosome biogenesis (IEA)

sensory perception of pain (ISO)

sensory perception of pain (ISO,ISS)

white fat cell differentiation (ISO)

Cellular Component

cis-Golgi network (ISO,ISS)

cytoplasm (IEA)

endoplasmic reticulum (ISO)

endoplasmic reticulum membrane (IEA,ISO,ISS)

nuclear body (ISO)

nucleolus (ISO)

obsolete integral component of endoplasmic reticulum membrane (ISO)

Molecular Function

endoplasmic reticulum-autophagosome adaptor activity (ISO)

nucleic acid binding (IEA)

protein binding (ISO)

protein self-association (ISO,ISS)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:19838196	PMID:26040720	PMID:32086669	PMID:32716134	PMID:34212292	PMID:36056188

Genomics

Comparative Map Data

Retreg1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	76,335,609 - 76,474,817 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	76,335,609 - 76,493,898 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	83,455,839 - 83,595,059 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	81,577,567 - 81,716,777 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	76,582,768 - 76,722,071 (+)	NCBI	Rnor_WKY
Rnor_6.0	2	78,391,921 - 78,401,569 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	78,391,921 - 78,399,987 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	2	78,103,387 - 78,276,927 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	97,821,407 - 97,972,821 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	77,470,558 - 77,566,123 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	72,093,456 - 72,182,485 (+)	NCBI		Celera
Cytogenetic Map	2	q22	NCBI

RETREG1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	16,473,053 - 16,616,997 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	5	16,473,038 - 16,617,101 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	16,473,162 - 16,617,106 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	16,526,147 - 16,670,118 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	16,496,766 - 16,640,783 (-)	NCBI		Celera
Cytogenetic Map	5	p15.1	NCBI
HuRef	5	16,445,059 - 16,589,261 (-)	NCBI		HuRef
CHM1_1	5	16,473,095 - 16,617,108 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	16,412,398 - 16,556,330 (-)	NCBI		T2T-CHM13v2.0

Retreg1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	25,840,795 - 25,973,782 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	25,843,266 - 25,973,773 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	25,843,298 - 25,973,696 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	25,843,180 - 25,973,687 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	25,773,019 - 25,903,442 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	25,787,989 - 25,918,412 (+)	NCBI		MGSCv36	mm8
Celera	15	26,616,789 - 26,745,263 (+)	NCBI		Celera
Cytogenetic Map	15	B1	NCBI

Retreg1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	5,574,216 - 5,688,236 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955426	5,574,207 - 5,688,236 (-)	NCBI	ChiLan1.0	ChiLan1.0

RETREG1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	5	16,612,583 - 16,756,808 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	5	16,774,596 - 16,920,948 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

RETREG1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	86,817,391 - 86,921,119 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	86,323,200 - 86,438,561 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	87,442,470 - 87,564,197 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	87,442,238 - 87,587,920 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	86,965,905 - 87,080,546 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	87,202,448 - 87,317,283 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	88,059,445 - 88,174,500 (+)	NCBI		UU_Cfam_GSD_1.0

Retreg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	210,176,692 - 210,316,851 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	19,114,768 - 19,253,352 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936480	19,114,753 - 19,253,346 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RETREG1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	5,726,494 - 5,879,714 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	5,726,493 - 5,879,461 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	6,170,402 - 6,324,535 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RETREG1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	16,153,003 - 16,297,252 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	16,154,694 - 16,297,161 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666064	12,181,901 - 12,326,336 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Retreg1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	13,376,502 - 13,501,918 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624751	13,377,583 - 13,502,144 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Retreg1
571 total Variants

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	5873687	102844969	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	25413423	143657569	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	81754745	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	127469484	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	26917817	136917119	Rat
10755436	Coatc8	Coat color QTL 8		0.02431	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	35023117	80023117	Rat
61371	Edpm1	Estrogen-dependent pituitary mass QTL 1	4	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	35134841	88029593	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	40067944	102785628	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	157142209	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	182042367	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	43154682	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
2293676	Bmd19	Bone mineral density QTL 19	10.7	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	43162366	111362592	Rat
2293682	Bmd24	Bone mineral density QTL 24	8.9	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	43162366	111362592	Rat
2293671	Bss44	Bone structure and strength QTL 44	10.97	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	2	43162366	148478373	Rat
631208	Bw1	Body weight QTL1	5.09		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	2	43171017	83575226	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	43171017	184114403	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
1582246	Cm60	Cardiac mass QTL 60	5.8		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	57605612	76539510	Rat
1558648	Smcn1	Smooth muscle cell number QTL 1		0.039	blood vessel smooth muscle cell quantity (VT:0010525)	aorta smooth muscle cell count per unit vessel length (CMO:0001646)	2	59134147	127460910	Rat
5684990	Bmd82	Bone mineral density QTL 82	2.8		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	2	59324377	103795077	Rat
5684996	Bmd85	Bone mineral density QTL 85	4.7	0.024	tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	2	59324377	103795077	Rat
61438	Cia7	Collagen induced arthritis QTL 7	4.6	0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	2	59324377	141596857	Rat
631500	Bp99	Blood pressure QTL 99	2.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	59324719	102755241	Rat
1578777	Stresp15	Stress response QTL 15	2	0.05	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	2	59846005	104846005	Rat
2306903	Bp336	Blood pressure QTL 336		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	64366971	109366971	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
7411551	Bw131	Body weight QTL 131	29.6	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	2	67942638	112942638	Rat
1558653	Prcr1	Prostate cancer resistance QTL 1	5		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	2	72532993	157142209	Rat
1359034	Bp274	Blood pressure QTL 274			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	74786664	94359546	Rat
1359034	Bp274	Blood pressure QTL 274			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	74786664	94359546	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat

Markers in Region

RH132335

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	76,336,677 - 76,336,866 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	78,104,525 - 78,104,713	NCBI	Rnor6.0
Rnor_5.0	2	97,822,444 - 97,822,632	UniSTS	Rnor5.0
RGSC_v3.4	2	77,420,241 - 77,420,429	UniSTS	RGSC3.4
Celera	2	72,045,887 - 72,046,075	UniSTS
RH 3.4 Map	2	498.9	UniSTS
Cytogenetic Map	2	q22	UniSTS

RH143838

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	76,473,375 - 76,473,490 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	78,400,141 - 78,400,255	NCBI	Rnor6.0
Rnor_6.0	2	78,255,668 - 78,255,782	NCBI	Rnor6.0
Rnor_5.0	2	97,971,380 - 97,971,494	UniSTS	Rnor5.0
RGSC_v3.4	2	77,564,695 - 77,564,809	UniSTS	RGSC3.4
Celera	2	72,181,057 - 72,181,171	UniSTS
RH 3.4 Map	2	503.0	UniSTS
Cytogenetic Map	2	q22	UniSTS

BE120148

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	45,153,049 - 45,153,261 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	48,299,786 - 48,299,997	NCBI	Rnor6.0
Rnor_5.0	16	48,011,849 - 48,012,060	UniSTS	Rnor5.0
RGSC_v3.4	16	48,376,260 - 48,376,471	UniSTS	RGSC3.4
RGSC_v3.4	2	77,468,539 - 77,468,750	UniSTS	RGSC3.4
Celera	16	43,159,457 - 43,159,668	UniSTS
RH 3.4 Map	16	451.5	UniSTS
Cytogenetic Map	2	q22	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001034912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC113901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY310142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY321329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089887	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000063951 ⟹ ENSRNOP00000062258

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	76,335,609 - 76,474,796 (+)	Ensembl
Rnor_6.0 Ensembl	2	78,103,387 - 78,257,134 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000066879 ⟹ ENSRNOP00000060898

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	78,262,839 - 78,276,927 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000079455 ⟹ ENSRNOP00000069183

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	76,441,501 - 76,474,802 (+)	Ensembl
Rnor_6.0 Ensembl	2	78,391,921 - 78,399,987 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000084541 ⟹ ENSRNOP00000075424

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	76,463,167 - 76,493,898 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089551 ⟹ ENSRNOP00000073087

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	76,468,405 - 76,488,847 (+)	Ensembl
Rnor_6.0 Ensembl	2	78,245,459 - 78,271,382 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089805 ⟹ ENSRNOP00000075409

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	76,443,711 - 76,474,802 (+)	Ensembl
Rnor_6.0 Ensembl	2	78,247,448 - 78,255,514 (+)	Ensembl

RefSeq Acc Id:

NM_001034912 ⟹ NP_001030084

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	76,335,609 - 76,474,804 (+)	NCBI
Rnor_6.0	2	78,391,921 - 78,401,569 (+)	NCBI
Rnor_5.0	2	97,821,407 - 97,972,821 (+)	NCBI
RGSC_v3.4	2	77,470,558 - 77,566,123 (+)	RGD
Celera	2	72,093,456 - 72,182,485 (+)	RGD

Sequence:

show sequence

CGCCAGGCGCGCGCGCGCGCGTGCCCGCCCGCCTCCCTCCCTGTCCCCGTCCCCATCCCCGTCC
CCGCCAGCAAAACACCGCTGAAGATGGCGAGCCCGGCGCCGGAGGAGCACGCCACGCAGGGATG
CCCAGCTACGGAGGAGCAGGAACCGCGACCCGGGGTTCCCGGGGAGGAGGCAGGGCCGGAGGGC
GCCGGGCCGCAGGTGGAGGAGGCCGCGGGCAGAGTGGCCGCCGCCCTGACCTGGCTACTCGGGG
AGCCCGTGCTGTGGCTGGGCTGGCGCGCCGACGAGCTCCTGAGCTGGAAGAGGCCGCTGCGCAG
CCTGCTCGCCTTCCTGGGTGCCAACCTGCTGTTCTGGTTCCTTGCCTTGACTCCGTGGAGAGTG
TATCATCTCATTTCTGTCATGATACTTGGTCGTGTTATCATGCAAATCATCAAGGACATGGTTT
TGTCCAGGGCAAGAGGTGCACAGTTGTGGAGGAGCCTCAGTGAAAGCTGGGAAGTTATCAATTC
CAAGCCAGATGAAAGACCCAGACTGAGCCACTGCATTGCAGAATCATGGATGAATTTCAGCATA
TTTCTTCAAGAAATGTCTCTTTTCAAACAGCAGAGCCCTGGCAAGTTTTGCCTCCTGGTCTGCA
GTGTGTGCACATTTTTTACAATCTTGGGAAGTTACATTCCTGGGGTCATTCTCAGCTACCTACT
GTTACTGTTTGCTTTTTTGTGTCCACTGTTTAAATGTAATGATATTGGACAAAAAATATACAGC
AAAGTCAAGTCCATTCTATTAAAACTAGATTTTGGAATTGGAGAATATATTAACCAGAAGAAAC
GTGAGAGATCTGAAGCAGATAAAGAAAAAAGCCACAAGGATGACAGTGAAATAGACTTTTCGGC
TCTTTGTCCTAAGATTAGCCTCACAGTTGCTGCCAAAGAGTTATCCGTGTCAGACACAGATGTG
TCAGAAGTCTCTTGGACTGATAATGGGACCTTCAACCTTTCAGAGGGGTACACTCCACAGACAG
ACACTTCTGATGATCTTGACCGGCCCAGTGAGGAAGTGTTCTCTCGAGATCTTTCAGATTTTCC
ATCTCTGGAAAATGGCGCGGGAACAAATGATGAAGATGAGTTAAGCCTTGGCTTACCCACAGAG
CTCAAGACAAAGAAGCAACAGTTGAACAGTGCTCACAGACCAAGCAAAGACAGGCAGTCAGCAG
CTGGCCTCTCACTTCCTCTCAAGAGCGACCAAGCCCTTCACTTGATGAGCAACCTGGCTGGGGA
TGTCATCACAGCTGCCATGACAGCTGCCATCAAAGACCAGCTAGAAGGGGCCCGGCAGGCCCTC
GCTCAGGCGGCGCCCACTCCAGGGGACGACACAGACACTGAGGAGGGGGATGATTTTGAACTAC
TTGACCAGGCAGAGCTAGATCAAATTGAGAGTGAGCTGGGACTAACACAAGACCAAGGGGCAGA
AGCCCAGCAAAGTAAGAAGTCCTCAGGCTTCCTTTCAAACCTGCTTGGAGGCCATTAGCCGGGA
ATCAGCTTGCCGCAAAGCACAGATAAACCACCCAAACATTTCAAACAAGCAGGGGGAAAAATGG
AAAAAAAATTGAATTGTAAGCTTTAATTACTTTAGATTTTTTGTTTTCTTTTCCCTTCTATAGT
GAGTTGGATATGTATCAGCTGATAATGATAGACTGACATTTCTGGTAGTTATTTTTATGTAATA
AGCATGGAAATGAACTTTATAGTTACATATATACATACTGTGGTGTCATAAGTGCTTAGGGGCT
GTTTGTAAAGAGAAACAAAAAAACCACATCAAACCCCATCAAACTGAGGTCTTTCTATAAGTAA
TCTTTTTCTTTATAATTTTCAAGCATGCAGAGATCGACAGCTGTGAACACACATGGCATCGGCC
CCCTAATTACTCCTCTTGGAAGTGGTTTATCAAATTCTGATAGATTTCAATGTAAAAAAGGAGA
AATATCAAAATGTTTGTAGTTGAAGGGCTATGGAAATGCTATCAAAATTAATTTTCTAGGAAAA
ACTTTAAAAATAAGTACTATCTATAGGCTGAAATATTTCCATGTTATTTCTACAGTTGTAGACA
GAGGCTTACTTGTCAGGTGGCATGCTCCACTGACTGCCACATCTAGTCTTGAAAAGAGGTGGTA
CTGACCCACAGAAAGCAGCCAGTTCTGTGTCTCTTCATGATGCTCTTGTAATGTTTGCAATGGT
AAGTGCACACTATTTTGCACACTCAGATGTAAGCAAAACCTGACGTTTCTGTAATGTGTTCCAG
TCTCCTAGGATTGTGAATCTAGTTATAGGTATGTCCATGAGTGATGTGCTCATTGGTGATCATC
AACACCCCCCCTTTTTTTTTCAGTTTACAAATGCAGAACAGAGGAACTTGCTTGAACTTTAAAG
TTTATTTCTCTGCCGCTGCACTCTCAATATGCAATCCGTTTCTTACTGGGAAGCTAGTGTATGC
TTTTTCCTTTAAACTGTTTTTTTTTGATCACTTTTACATAATCAAATTTGACTTACAGTGGAAA
CCAAGATAGTTGTTTTTGTGAAACAATCTTTTAGAAGGACTGAGGGACCATGTCAGCAAATATC
TTAGATCTTCAGTTATAGCTGGCATTTCTACACAGACACACAAGATCCTTACAAAGGAAGGGTA
ATCTAAGACTGTAGAAGTCTGTGTTTCAGTTTCATCTCTTTTATTTCTAAAGACTAATTACAGG
TAACTTGACCTTTTAATGCACCATCTCCTATTTATTTATTTTTTTCTCTCTGAGGTATTAAAAA
TATCAAGACTGAATTTTGCCAAATGTAAGAGGGAGGAAAGTCCCTGAAGACTCTGACTACTTGC
TTATTTTTGATTGACCTTCTATGCTTATGTCATTAGTGCCTCACAACTGTGTTTGACGTCCTTT
ATTGATACAGAGTGAGCCTGTGCCTTCATTTTCTTGCCCATTTTGGTACTGATGTAAATTTGTG
TTAGAAAATCTTGGAACTCTGTGAGTCTGGGAAGAATATATCTGAATCCTATTCAATACATTTG
CTGGATGTGAAGAAAAATACAGCCACATATTTATAAAACAAAAAAAAAAAAAAAAAAAAAAAAA
AAAA

hide sequence

RefSeq Acc Id:

XM_006232084 ⟹ XP_006232146

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	76,441,262 - 76,474,817 (+)	NCBI

Sequence:

show sequence

TGTGACTCAAAGGAGATTGGATAGCTGGAGTGAGGTTTCAACCTGCCTGTGGCTACTCCACCTT
TTGGTAGGCGCCTAGATCTTGCCAGGAAAAAAAAAAAAAAGGAAAGAGGGCAGCAGGCGGCTGG
GTGAAGTCATCCCTGGTGACACCTTCTCACAGGACTTCAGGGAAAATGCTGGGCGACTGGGCAG
TGCCTCTGCCCAGCTGCCTGTCACGGTGCTGGGAGTGAGAGGTGACCTCTTTATTTTTAGCAGG
GGGCTGTCAGGAGAGTTCACTCCTCTGCTTCATCCAAGACAGGAGGCAGTCACTTTGGAAGTTT
GTAAACACCGACTTTCTCAGTAGAGGTGGGACACTTTTCTCCAGAAAGGGAAGAATTTCCCTGC
CGGGGTTTCCCTCTTCTTAGAGTCGCACTGTGGACAAGACAGCGATCTTTGGCTGTCTGAGTTG
TGGCAAGCAGGCGCCGCTCAAGTTCTAATTATTACAGGGCAGTCATGCCTGCCGGCGACGGCTG
TGGACCAGGCAGAAGCTGGGAAGTTATCAATTCCAAGCCAGATGAAAGACCCAGACTGAGCCAC
TGCATTGCAGAATCATGGATGAATTTCAGCATATTTCTTCAAGAAATGTCTCTTTTCAAACAGC
AGAGCCCTGGCAAGTTTTGCCTCCTGGTCTGCAGTGTGTGCACATTTTTTACAATCTTGGGAAG
TTACATTCCTGGGGTCATTCTCAGCTACCTACTGTTACTGTTTGCTTTTTTGTGTCCACTGTTT
AAATGTAATGATATTGGACAAAAAATATACAGCAAAGTCAAGTCCATTCTATTAAAACTAGATT
TTGGAATTGGAGAATATATTAACCAGAAGAAACGTGAGAGATCTGAAGCAGATAAAGAAAAAAG
CCACAAGGATGACAGTGAAATAGACTTTTCGGCTCTTTGTCCTAAGATTAGCCTCACAGTTGCT
GCCAAAGAGTTATCCGTGTCAGACACAGATGTGTCAGAAGTCTCTTGGACTGATAATGGGACCT
TCAACCTTTCAGAGGGGTACACTCCACAGACAGACACTTCTGATGATCTTGACCGGCCCAGTGA
GGAAGTGTTCTCTCGAGATCTTTCAGATTTTCCATCTCTGGAAAATGGCGCGGGAACAAATGAT
GAAGATGAGTTAAGCCTTGGCTTACCCACAGAGCTCAAGACAAAGAAGCAACAGTTGAACAGTG
CTCACAGACCAAGCAAAGACAGGCAGTCAGCAGCTGGCCTCTCACTTCCTCTCAAGAGCGACCA
AGCCCTTCACTTGATGAGCAACCTGGCTGGGGATGTCATCACAGCTGCCATGACAGCTGCCATC
AAAGACCAGCTAGAAGGGGCCCGGCAGGCCCTCGCTCAGGCGGCGCCCACTCCAGGGGACGACA
CAGACACTGAGGAGGGGGATGATTTTGAACTACTTGACCAGGCAGAGCTAGATCAAATTGAGAG
TGAGCTGGGACTAACACAAGACCAAGGGGCAGAAGCCCAGCAAAGTAAGAAGTCCTCAGGCTTC
CTTTCAAACCTGCTTGGAGGCCATTAGCCGGGAATCAGCTTGCCGCAAAGCACAGATAAACCAC
CCAAACATTTCAAACAAGCAGGGGGAAAAATGGAAAAAAAATTGAATTGTAAGCTTTAATTACT
TTAGATTTTTTGTTTTCTTTTCCCTTCTATAGTGAGTTGGATATGTATCAGCTGATAATGATAG
ACTGACATTTCTGGTAGTTATTTTTATGTAATAAGCATGGAAATGAACTTTATAGTTACATATA
TACATACTGTGGTGTCATAAGTGCTTAGGGGCTGTTTGTAAAGAGAAACAAAAAAACCACATCA
AACCCCATCAAACTGAGGTCTTTCTATAAGTAATCTTTTTCTTTATAATTTTCAAGCATGCAGA
GATCGACAGCTGTGAACACACATGGCATCGGCCCCCTAATTACTCCTCTTGGAAGTGGTTTATC
AAATTCTGATAGATTTCAATGTAAAAAAGGAGAAATATCAAAATGTTTGTAGTTGAAGGGCTAT
GGAAATGCTATCAAAATTAATTTTCTAGGAAAAACTTTAAAAATAAGTACTATCTATAGGCTGA
AATATTTCCATGTTATTTCTACAGTTGTAGACAGAGGCTTACTTGTCAGGTGGCATGCTCCACT
GACTGCCACATCTAGTCTTGAAAAGAGGTGGTACTGACCCACAGAAAGCAGCCAGTTCTGTGTC
TCTTCATGATGCTCTTGTAATGTTTGCAATGGTAAGTGCACACTATTTTGCACACTCAGATGTA
AGCAAAACCTGACGTTTCTGTAATGTGTTCCAGTCTCCTAGGATTGTGAATCTAGTTATAGGTA
TGTCCATGAGTGATGTGCTCATTGGTGATCATCAACACCCCCCCTTTTTTTTTCAGTTTACAAA
TGCAGAACAGAGGAACTTGCTTGAACTTTAAAGTTTATTTCTCTGCCGCTGCACTCTCAATATG
CAATCCGTTTCTTACTGGGAAGCTAGTGTATGCTTTTTCCTTTAAACTGTTTTTTTTTGATCAC
TTTTACATAATCAAATTTGACTTACAGTGGAAACCAAGATAGTTGTTTTTGTGAAACAATCTTT
TAGAAGGACTGAGGGACCATGTCAGCAAATATCTTAGATCTTCAGTTATAGCTGGCATTTCTAC
ACAGACACACAAGATCCTTACAAAGGAAGGGTAATCTAAGACTGTAGAAGTCTGTGTTTCAGTT
TCATCTCTTTTATTTCTAAAGACTAATTACAGGTAACTTGACCTTTTAATGCACCATCTCCTAT
TTATTTATTTTTTTCTCTCTGAGGTATTAAAAATATCAAGACTGAATTTTGCCAAATGTAAGAG
GGAGGAAAGTCCCTGAAGACTCTGACTACTTGCTTATTTTTGATTGACCTTCTATGCTTATGTC
ATTAGTGCCTCACAACTGTGTTTGACGTCCTTTATTGATACAGAGTGAGCCTGTGCCTTCATTT
TCTTGCCCATTTTGGTACTGATGTAAATTTGTGTTAGAAAATCTTGGAACTCTGTGAGTCTGGG
AAGAATATATCTGAATCCTATTCAATACATTTGCTGGATGTGAAGAAAAATACAGCCACATATT
TATAAAACAGTTGTTACCAGTA

hide sequence

RefSeq Acc Id:

XM_039103026 ⟹ XP_038958954

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	76,400,342 - 76,474,817 (+)	NCBI

RefSeq Acc Id:

XM_039103027 ⟹ XP_038958955

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	76,400,583 - 76,474,817 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001030084	(Get FASTA)	NCBI Sequence Viewer
	XP_006232146	(Get FASTA)	NCBI Sequence Viewer
	XP_038958954	(Get FASTA)	NCBI Sequence Viewer
	XP_038958955	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89887	(Get FASTA)	NCBI Sequence Viewer
	AAP78750	(Get FASTA)	NCBI Sequence Viewer
	AAP86261	(Get FASTA)	NCBI Sequence Viewer
	EDL82614	(Get FASTA)	NCBI Sequence Viewer
	EDL82615	(Get FASTA)	NCBI Sequence Viewer
	EDL82616	(Get FASTA)	NCBI Sequence Viewer
	EDL82617	(Get FASTA)	NCBI Sequence Viewer
	EDL82618	(Get FASTA)	NCBI Sequence Viewer
	Q5FVM3	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001030084 ⟸ NM_001034912

- UniProtKB:

Q5FVM3 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MASPAPEEHATQGCPATEEQEPRPGVPGEEAGPEGAGPQVEEAAGRVAAALTWLLGEPVLWLGW
RADELLSWKRPLRSLLAFLGANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVLSRARGAQ
LWRSLSESWEVINSKPDERPRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTI
LGSYIPGVILSYLLLLFAFLCPLFKCNDIGQKIYSKVKSILLKLDFGIGEYINQKKRERSEADK
EKSHKDDSEIDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDR
PSEEVFSRDLSDFPSLENGAGTNDEDELSLGLPTELKTKKQQLNSAHRPSKDRQSAAGLSLPLK
SDQALHLMSNLAGDVITAAMTAAIKDQLEGARQALAQAAPTPGDDTDTEEGDDFELLDQAELDQ
IESELGLTQDQGAEAQQSKKSSGFLSNLLGGH

hide sequence

RefSeq Acc Id:

ENSRNOP00000069183 ⟸ ENSRNOT00000079455

RefSeq Acc Id:	XP_038958954 ⟸ XM_039103026
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038958955 ⟸ XM_039103027
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_006232146 ⟸ XM_006232084
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JUQ3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPAGDGCGPGRSWEVINSKPDERPRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCT FFTILGSYIPGVILSYLLLLFAFLCPLFKCNDIGQKIYSKVKSILLKLDFGIGEYINQKKRERS EADKEKSHKDDSEIDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSD DLDRPSEEVFSRDLSDFPSLENGAGTNDEDELSLGLPTELKTKKQQLNSAHRPSKDRQSAAGLS LPLKSDQALHLMSNLAGDVITAAMTAAIKDQLEGARQALAQAAPTPGDDTDTEEGDDFELLDQA ELDQIESELGLTQDQGAEAQQSKKSSGFLSNLLGGH hide sequence

RefSeq Acc Id:

ENSRNOP00000062258 ⟸ ENSRNOT00000063951

RefSeq Acc Id:

ENSRNOP00000075409 ⟸ ENSRNOT00000089805

RefSeq Acc Id:

ENSRNOP00000073087 ⟸ ENSRNOT00000089551

RefSeq Acc Id:

ENSRNOP00000060898 ⟸ ENSRNOT00000066879

RefSeq Acc Id:

ENSRNOP00000075424 ⟸ ENSRNOT00000084541

Protein Domains

C2H2-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FVM3-F1-model_v2	AlphaFold	Q5FVM3	1-480	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565003	AgrOrtholog
BioCyc Gene	G2FUF-53940	BioCyc
Ensembl Genes	ENSRNOG00000010589	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00000057522	Ensembl
Ensembl Protein	ENSRNOP00000062258	ENTREZGENE
	ENSRNOP00000062258.2	UniProtKB/Swiss-Prot
	ENSRNOP00000069183	ENTREZGENE
	ENSRNOP00000069183.2	UniProtKB/TrEMBL
	ENSRNOP00000073087.2	UniProtKB/TrEMBL
	ENSRNOP00000075409	ENTREZGENE
	ENSRNOP00000075409.2	UniProtKB/TrEMBL
	ENSRNOP00000075424.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000063951	ENTREZGENE
	ENSRNOT00000063951.4	UniProtKB/Swiss-Prot
	ENSRNOT00000079455	ENTREZGENE
	ENSRNOT00000079455.2	UniProtKB/TrEMBL
	ENSRNOT00000084541.2	UniProtKB/TrEMBL
	ENSRNOT00000089551.2	UniProtKB/TrEMBL
	ENSRNOT00000089805	ENTREZGENE
	ENSRNOT00000089805.2	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7371502	IMAGE-MGC_LOAD
InterPro	RETREG1/3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZN622/Rei1/Reh1_Znf-C2H2	UniProtKB/TrEMBL
	Znf622/Rei1/Reh1	UniProtKB/TrEMBL
	Znf_C2H2_jaz	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
	Znf_U1	UniProtKB/TrEMBL
KEGG Report	rno:619558	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:109057	IMAGE-MGC_LOAD
NCBI Gene	619558	ENTREZGENE
PANTHER	PTHR13182	UniProtKB/TrEMBL
	PTHR28659	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR28659:SF3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 622	UniProtKB/TrEMBL
Pfam	zf-C2H2_2	UniProtKB/TrEMBL
	zf-C2H2_jaz	UniProtKB/TrEMBL
PhenoGen	Retreg1	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
SMART	ZnF_C2H2	UniProtKB/TrEMBL
	ZnF_U1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/TrEMBL
UniProt	A0A0G2JUQ3	ENTREZGENE, UniProtKB/TrEMBL
	A0A0G2K4L3_RAT	UniProtKB/TrEMBL
	A0A0G2KAI5_RAT	UniProtKB/TrEMBL
	A0A8L2URM4_RAT	UniProtKB/TrEMBL
	Q5FVM3	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Retreg1	reticulophagy regulator 1	LOC103689968	protein FAM134B	Data Merged	737654	PROVISIONAL
2017-03-27	Retreg1	reticulophagy regulator 1	Fam134b	family with sequence similarity 134, member B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-08-25	LOC103689968	protein FAM134B			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-03-05	Fam134b	family with sequence similarity 134, member B	LOC619558	hypothetical protein LOC619558	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	LOC619558	hypothetical protein LOC619558			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIA

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

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