Gapdhl10 (glyceraldehyde-3-phosphate dehydrogenase like 10) - Rat Genome Database

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Gene: Gapdhl10 (glyceraldehyde-3-phosphate dehydrogenase like 10) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Gapdhl10 (Ensembl: RGD1564958)
Name: glyceraldehyde-3-phosphate dehydrogenase like 10 (Ensembl:similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12))
RGD ID: 1564958
Description: Predicted to enable adenyl nucleotide binding activity; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; and transferase activity. Predicted to be involved in several processes, including glucose metabolic process; glycolytic process; and regulation of translation. Predicted to be located in cytoskeleton; cytosol; and nucleus; PARTICIPATES IN Alzheimer's disease pathway; gluconeogenesis pathway; glycolysis pathway; INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; ammonium chloride.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AABR07024795.1; glyceraldehyde-3-phosphate dehydrogenase-like; LOC290604; RGD1564958; similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12); similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12)
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81615,391,984 - 15,392,965 (+)NCBIGRCr8
mRatBN7.21615,370,290 - 15,371,300 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1615,370,293 - 15,371,300 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01616,948,541 - 16,950,239 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1616,949,232 - 16,950,239 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01616,834,721 - 16,835,728 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41615,834,994 - 15,836,001 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1615,599,830 - 15,600,726 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoskeleton  (IEA)
cytosol  (IBA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Gapdhl10
6 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)16285170915884239Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760916039848Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16422773017696785Rat

Markers in Region
PMC133764P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q22UniSTS
Cytogenetic Map9q13UniSTS
Cytogenetic Map16q11UniSTS
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map18q12.1UniSTS
PMC26839P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16q11UniSTS
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map19p11UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map18q12.1UniSTS
PMC316856P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16q11UniSTS
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map10q32.1UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map18q12.1UniSTS
PMC327192P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map19p11UniSTS


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000047499   ⟹   ENSRNOP00000074716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1615,370,293 - 15,371,300 (+)Ensembl
RefSeq Acc Id: XM_017600426   ⟹   XP_017455915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81615,391,984 - 15,392,965 (+)NCBI
mRatBN7.21615,370,290 - 15,371,300 (+)NCBI
Rnor_6.01616,948,541 - 16,950,239 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_017455915 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074716.1
RefSeq Acc Id: XP_017455915   ⟸   XM_017600426
- Sequence:
RefSeq Acc Id: ENSRNOP00000074716   ⟸   ENSRNOT00000047499
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K8S2-F1-model_v2 AlphaFold A0A0G2K8S2 1-335 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564958 AgrOrtholog
BioCyc Gene G2FUF-11954 BioCyc
Ensembl Genes ENSRNOG00000028958 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047499.3 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro GlycerAld/Erythrose_P_DH UniProtKB/TrEMBL
  GlycerAld_3-P_DH_cat UniProtKB/TrEMBL
  GlycerAld_3-P_DH_NAD(P)-bd UniProtKB/TrEMBL
  Glyceraldehyde-3-P_DH_1 UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene 290604 ENTREZGENE
PANTHER GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE UniProtKB/TrEMBL
  PTHR10836 UniProtKB/TrEMBL
Pfam Gp_dh_C UniProtKB/TrEMBL
  Gp_dh_N UniProtKB/TrEMBL
PhenoGen Gapdhl10 PhenoGen
PIRSF GAP_DH UniProtKB/TrEMBL
PRINTS G3PDHDRGNASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028958 RatGTEx
SMART Gp_dh_N UniProtKB/TrEMBL
Superfamily-SCOP Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
UniProt A0A0G2K8S2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Gapdhl10  glyceraldehyde-3-phosphate dehydrogenase like 10  RGD1564958  similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12)  Symbol and Name Changed 1299863 APPROVED
2022-06-02 RGD1564958  similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12)  AABR07024795.1    Data merged from RGD:15003714 737654 PROVISIONAL
2019-11-08 AABR07024795.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 RGD1564958  similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12)   RGD1564958_predicted  similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-10 RGD1564958_predicted  similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) (predicted)    similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) - mouse (predicted)  Name updated 1299863 APPROVED
2006-03-07 RGD1564958_predicted  similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) - mouse (predicted)  LOC290604  similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) - mouse  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC290604  similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) - mouse      Symbol and Name status set to provisional 70820 PROVISIONAL