Taf7l (TATA-box binding protein associated factor 7-like) - Rat Genome Database

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Gene: Taf7l (TATA-box binding protein associated factor 7-like) Rattus norvegicus
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Symbol: Taf7l
Name: TATA-box binding protein associated factor 7-like
RGD ID: 1564898
Description: Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to act upstream of or within flagellated sperm motility and spermatid development. Predicted to be located in cytoplasm and male germ cell nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to human TAF7L (TATA-box binding protein associated factor 7 like); INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363493; RGD1564898; similar to TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor; transcription initiation factor TFIID subunit 7-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Taf7l-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X101,953,508 - 101,968,336 (-)NCBIGRCr8
mRatBN7.2X97,660,222 - 97,675,241 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,660,222 - 97,675,023 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,334,442 - 99,349,219 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X102,844,839 - 102,859,624 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,347,599 - 100,362,376 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X105,292,338 - 105,308,554 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,292,338 - 105,308,554 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,183,229 - 105,199,248 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,935,672 - 121,950,719 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX98,701,715 - 98,716,468 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12665565   PMID:15927180   PMID:17242199   PMID:38112167  


Genomics

Comparative Map Data
Taf7l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X101,953,508 - 101,968,336 (-)NCBIGRCr8
mRatBN7.2X97,660,222 - 97,675,241 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,660,222 - 97,675,023 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,334,442 - 99,349,219 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X102,844,839 - 102,859,624 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,347,599 - 100,362,376 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X105,292,338 - 105,308,554 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,292,338 - 105,308,554 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,183,229 - 105,199,248 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,935,672 - 121,950,719 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX98,701,715 - 98,716,468 (-)NCBICelera
Cytogenetic MapXq32NCBI
TAF7L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X101,268,257 - 101,293,083 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX101,268,253 - 101,293,057 (-)EnsemblGRCh38hg38GRCh38
GRCh37X100,523,245 - 100,548,071 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,409,897 - 100,434,701 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X100,329,386 - 100,354,190NCBI
CeleraX101,042,015 - 101,067,533 (-)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX90,326,711 - 90,351,477 (-)NCBIHuRef
CHM1_1X100,417,044 - 100,441,569 (-)NCBICHM1_1
T2T-CHM13v2.0X99,712,369 - 99,751,819 (-)NCBIT2T-CHM13v2.0
Taf7l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X133,360,865 - 133,377,254 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX133,360,867 - 133,377,239 (-)EnsemblGRCm39 Ensembl
GRCm38X134,460,116 - 134,476,505 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,460,118 - 134,476,490 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X130,994,655 - 131,011,029 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X129,806,469 - 129,822,644 (-)NCBIMGSCv36mm8
CeleraX117,338,620 - 117,355,092 (-)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX56.18NCBI
Taf7l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555037,429,876 - 7,451,051 (-)NCBIChiLan1.0ChiLan1.0
TAF7L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X100,868,104 - 100,897,866 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X100,871,714 - 100,897,257 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X90,471,354 - 90,496,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X100,607,488 - 100,631,301 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,607,488 - 100,631,301 (-)Ensemblpanpan1.1panPan2
TAF7L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X75,219,448 - 75,238,309 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX75,220,248 - 75,239,041 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X76,642,213 - 76,661,089 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX76,642,205 - 76,661,681 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X74,203,965 - 74,222,831 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,864,367 - 75,883,225 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X75,626,775 - 75,645,651 (-)NCBIUU_Cfam_GSD_1.0
Taf7l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,096,626 - 63,134,131 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936813357,571 - 372,736 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936813357,571 - 378,479 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAF7L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX82,930,266 - 82,951,224 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X82,930,258 - 82,951,065 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X90,962,646 - 90,983,465 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TAF7L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,610,238 - 89,636,238 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX89,611,208 - 89,635,921 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606514,526,792 - 14,552,570 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Taf7l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249021,243,817 - 1,256,209 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249021,239,776 - 1,267,443 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Taf7l
49 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:76
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000045556
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat

Markers in Region
RH128583  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X97,660,400 - 97,660,620 (+)MAPPERmRatBN7.2
Rnor_6.0X105,292,517 - 105,292,736NCBIRnor6.0
Rnor_5.0X105,183,408 - 105,183,627UniSTSRnor5.0
RGSC_v3.4X121,935,851 - 121,936,070UniSTSRGSC3.4
CeleraX98,701,894 - 98,702,113UniSTS
Cytogenetic MapXq34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
2 3 5 82 29 25 7 14 7 1 50 33 68 5 55 18

Sequence


Ensembl Acc Id: ENSRNOT00000045556   ⟹   ENSRNOP00000048993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,660,222 - 97,675,023 (-)Ensembl
Rnor_6.0 EnsemblX105,292,338 - 105,308,554 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102985   ⟹   ENSRNOP00000083355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,660,222 - 97,675,023 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118272   ⟹   ENSRNOP00000090554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,661,662 - 97,675,023 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119793   ⟹   ENSRNOP00000092025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,660,222 - 97,673,136 (-)Ensembl
RefSeq Acc Id: NM_001135877   ⟹   NP_001129349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,953,508 - 101,968,285 (-)NCBI
mRatBN7.2X97,660,222 - 97,675,001 (-)NCBI
Rnor_6.0X105,292,338 - 105,308,554 (-)NCBI
Rnor_5.0X105,183,229 - 105,199,248 (-)NCBI
RGSC_v3.4X121,935,672 - 121,950,719 (-)RGD
CeleraX98,701,715 - 98,716,468 (-)RGD
Sequence:
RefSeq Acc Id: XM_039099902   ⟹   XP_038955830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,953,508 - 101,968,336 (-)NCBI
mRatBN7.2X97,660,222 - 97,675,241 (-)NCBI
RefSeq Acc Id: XM_039099903   ⟹   XP_038955831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,953,508 - 101,967,121 (-)NCBI
mRatBN7.2X97,660,222 - 97,673,689 (-)NCBI
RefSeq Acc Id: NP_001129349   ⟸   NM_001135877
- Sequence:
Ensembl Acc Id: ENSRNOP00000048993   ⟸   ENSRNOT00000045556
RefSeq Acc Id: XP_038955830   ⟸   XM_039099902
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038955831   ⟸   XM_039099903
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000092025   ⟸   ENSRNOT00000119793
Ensembl Acc Id: ENSRNOP00000090554   ⟸   ENSRNOT00000118272
Ensembl Acc Id: ENSRNOP00000083355   ⟸   ENSRNOT00000102985
Protein Domains
TAFII55 protein conserved region

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AC01-F1-model_v2 AlphaFold D4AC01 1-465 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564898 AgrOrtholog
BioCyc Gene G2FUF-1687 BioCyc
Ensembl Genes ENSRNOG00000026315 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045556.4 UniProtKB/TrEMBL
  ENSRNOT00000102985.1 UniProtKB/TrEMBL
  ENSRNOT00000118272.1 UniProtKB/TrEMBL
  ENSRNOT00000119793.1 UniProtKB/TrEMBL
InterPro TAF7 UniProtKB/TrEMBL
  TAFII55_prot_cons_reg UniProtKB/TrEMBL
KEGG Report rno:363493 UniProtKB/TrEMBL
NCBI Gene 363493 ENTREZGENE
PANTHER PTHR12228 UniProtKB/TrEMBL
  TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 7-LIKE UniProtKB/TrEMBL
Pfam TAFII55_N UniProtKB/TrEMBL
PhenoGen Taf7l PhenoGen
RatGTEx ENSRNOG00000026315 RatGTEx
SMART TAFII55_N UniProtKB/TrEMBL
UniProt A0A8I5ZWV0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AD81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GIZ1_RAT UniProtKB/TrEMBL
  A6IVF5_RAT UniProtKB/TrEMBL
  D4AC01 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 Taf7l  TATA-box binding protein associated factor 7-like  Taf7l  TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Taf7l  TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor   Taf7l_predicted  TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Taf7l_predicted  TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor (predicted)  RGD1564898_predicted  similar to TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1564898_predicted  similar to TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor (predicted)  LOC363493  similar to TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC363493  similar to TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor      Symbol and Name status set to provisional 70820 PROVISIONAL