Usp46 (ubiquitin specific peptidase 46) - Rat Genome Database

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Pathways
Gene: Usp46 (ubiquitin specific peptidase 46) Rattus norvegicus
Analyze
Symbol: Usp46
Name: ubiquitin specific peptidase 46
RGD ID: 1564808
Description: Predicted to enable cysteine-type deubiquitinase activity. Involved in regulation of postsynaptic neurotransmitter receptor internalization. Is active in glutamatergic synapse. Orthologous to human USP46 (ubiquitin specific peptidase 46); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: deubiquitinating enzyme 46; LOC289584; RGD1564808; similar to ubiquitin specific protease 46; ubiquitin carboxyl-terminal hydrolase 46; ubiquitin specific protease 46; ubiquitin thioesterase 46; ubiquitin-specific-processing protease 46
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81434,504,074 - 34,573,318 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1434,504,118 - 34,573,307 (+)EnsemblGRCr8
mRatBN7.21434,150,055 - 34,219,227 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1434,150,004 - 34,219,227 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1434,498,501 - 34,567,643 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01435,806,080 - 35,875,235 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01434,291,567 - 34,360,710 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01436,687,134 - 36,755,360 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1436,687,134 - 36,755,360 (+)Ensemblrn6Rnor6.0
Rnor_5.01436,514,023 - 36,582,331 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41436,537,951 - 36,609,397 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1433,411,301 - 33,480,344 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO,ISS)
cytosol  (IBA)
glutamatergic synapse  (IDA,IEP,IMP)
nucleus  (IBA)
synapse  (IDA,IEP)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Histone arginine methylation in cocaine action in the nucleus accumbens. Damez-Werno DM, etal., Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9623-8. doi: 10.1073/pnas.1605045113. Epub 2016 Aug 9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The deubiquitinating enzyme USP46 regulates AMPA receptor ubiquitination and trafficking. Huo Y, etal., J Neurochem. 2015 Sep;134(6):1067-80. doi: 10.1111/jnc.13194. Epub 2015 Jul 16.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14715245   PMID:19075014   PMID:19465912   PMID:22043315   PMID:22720038   PMID:23472206   PMID:26811477  


Genomics

Comparative Map Data
Usp46
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81434,504,074 - 34,573,318 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1434,504,118 - 34,573,307 (+)EnsemblGRCr8
mRatBN7.21434,150,055 - 34,219,227 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1434,150,004 - 34,219,227 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1434,498,501 - 34,567,643 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01435,806,080 - 35,875,235 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01434,291,567 - 34,360,710 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01436,687,134 - 36,755,360 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1436,687,134 - 36,755,360 (+)Ensemblrn6Rnor6.0
Rnor_5.01436,514,023 - 36,582,331 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41436,537,951 - 36,609,397 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1433,411,301 - 33,480,344 (+)NCBICelera
Cytogenetic Map14p11NCBI
USP46
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38452,590,960 - 52,659,301 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl452,590,960 - 52,659,301 (-)Ensemblhg38GRCh38
GRCh37453,457,126 - 53,525,468 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36453,155,957 - 53,220,197 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34453,302,137 - 53,366,368NCBI
Celera450,953,085 - 51,021,473 (-)NCBICelera
Cytogenetic Map4q12NCBI
HuRef449,398,932 - 49,469,641 (-)NCBIHuRef
CHM1_1453,493,107 - 53,561,400 (-)NCBICHM1_1
T2T-CHM13v2.0456,077,847 - 56,146,196 (-)NCBIT2T-CHM13v2.0
Usp46
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39574,159,387 - 74,229,070 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl574,159,114 - 74,229,092 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38573,998,726 - 74,068,411 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl573,998,453 - 74,068,431 (-)Ensemblmm10GRCm38
MGSCv37574,396,062 - 74,464,436 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36574,281,734 - 74,350,108 (-)NCBIMGSCv36mm8
Celera571,261,248 - 71,329,058 (-)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map539.33NCBI
Usp46
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544717,900,611 - 17,971,601 (+)Ensembl
ChiLan1.0NW_00495544717,915,451 - 17,975,149 (+)NCBIChiLan1.0ChiLan1.0
USP46
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2377,158,903 - 77,226,968 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1477,363,811 - 77,431,907 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0471,305,286 - 71,373,257 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1477,861,053 - 77,926,591 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl477,861,053 - 77,920,759 (+)EnsemblpanPan2panpan1.1
USP46
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11345,381,974 - 45,475,212 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1345,384,641 - 45,439,096 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1345,333,292 - 45,426,735 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01345,989,512 - 46,083,600 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1345,989,456 - 46,083,672 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11345,656,947 - 45,752,306 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01345,192,629 - 45,286,238 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01346,069,223 - 46,162,546 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Usp46
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528530,694,489 - 30,760,632 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648215,538,504 - 15,603,693 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648215,539,123 - 15,603,733 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP46
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl839,517,512 - 39,581,727 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1839,518,155 - 39,581,990 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2841,642,107 - 41,703,244 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP46
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1715,821,206 - 15,891,058 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl715,821,284 - 15,887,550 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606616,787,584 - 16,860,932 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp46
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476116,939,590 - 17,009,037 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476116,939,562 - 17,014,069 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Usp46
391 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:485
Count of miRNA genes:254
Interacting mature miRNAs:341
Transcripts:ENSRNOT00000002879
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2324617Coatc2Coat color QTL 20.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)143076702539153750Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141863134542337007Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142216796767167967Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141762256142337007Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat

Markers in Region
RH130614  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81434,571,554 - 34,571,747 (+)Marker Load Pipeline
mRatBN7.21434,217,463 - 34,217,656 (+)MAPPERmRatBN7.2
Rnor_6.01436,753,597 - 36,753,789NCBIRnor6.0
Rnor_5.01436,580,568 - 36,580,760UniSTSRnor5.0
RGSC_v3.41436,607,634 - 36,607,826UniSTSRGSC3.4
Celera1433,478,581 - 33,478,773UniSTS
RH 3.4 Map14433.58UniSTS
Cytogenetic Map14p11UniSTS
RH143580  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21434,218,947 - 34,219,059 (+)MAPPERmRatBN7.2
Rnor_6.01436,755,081 - 36,755,192NCBIRnor6.0
Rnor_5.01436,582,052 - 36,582,163UniSTSRnor5.0
RGSC_v3.41436,609,118 - 36,609,229UniSTSRGSC3.4
Celera1433,480,065 - 33,480,176UniSTS
RH 3.4 Map14434.08UniSTS
Cytogenetic Map14p11UniSTS
BE102309  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21434,163,962 - 34,164,131 (+)MAPPERmRatBN7.2
Rnor_6.01436,701,036 - 36,701,204NCBIRnor6.0
Rnor_5.01436,528,007 - 36,528,175UniSTSRnor5.0
RGSC_v3.41436,553,102 - 36,553,270UniSTSRGSC3.4
Celera1433,425,225 - 33,425,393UniSTS
Cytogenetic Map14p11UniSTS
RH139292  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21434,194,259 - 34,194,392 (+)MAPPERmRatBN7.2
Rnor_6.01436,731,374 - 36,731,506NCBIRnor6.0
Rnor_5.01436,558,345 - 36,558,477UniSTSRnor5.0
RGSC_v3.41436,584,071 - 36,584,203UniSTSRGSC3.4
Celera1433,455,484 - 33,455,616UniSTS
RH 3.4 Map14378.08UniSTS
Cytogenetic Map14p11UniSTS
AI009635  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21434,216,809 - 34,217,014 (+)MAPPERmRatBN7.2
Rnor_6.01436,752,943 - 36,753,147NCBIRnor6.0
Rnor_5.01436,579,914 - 36,580,118UniSTSRnor5.0
RGSC_v3.41436,606,980 - 36,607,184UniSTSRGSC3.4
Celera1433,477,927 - 33,478,131UniSTS
RH 3.4 Map14380.08UniSTS
Cytogenetic Map14p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 13 78 202 91 90 59 157 59 6 476 277 21 181 109 122 31 34 34

Sequence


Ensembl Acc Id: ENSRNOT00000002879   ⟹   ENSRNOP00000002879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1434,504,118 - 34,573,307 (+)Ensembl
mRatBN7.2 Ensembl1434,150,004 - 34,219,227 (+)Ensembl
Rnor_6.0 Ensembl1436,687,134 - 36,755,360 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083100   ⟹   ENSRNOP00000072387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1434,180,697 - 34,219,227 (+)Ensembl
Rnor_6.0 Ensembl1436,689,096 - 36,752,141 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097061   ⟹   ENSRNOP00000080787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1434,506,681 - 34,573,190 (+)Ensembl
mRatBN7.2 Ensembl1434,152,504 - 34,219,227 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112025   ⟹   ENSRNOP00000080661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1434,150,131 - 34,219,227 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119848   ⟹   ENSRNOP00000086106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1434,180,190 - 34,219,227 (+)Ensembl
RefSeq Acc Id: NM_001191596   ⟹   NP_001178525
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81434,504,150 - 34,573,318 (+)NCBI
mRatBN7.21434,150,055 - 34,219,227 (+)NCBI
Rnor_6.01436,687,134 - 36,755,360 (+)NCBI
Rnor_5.01436,514,023 - 36,582,331 (+)NCBI
Celera1433,411,301 - 33,480,344 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250889   ⟹   XP_006250951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81434,506,591 - 34,573,311 (+)NCBI
mRatBN7.21434,152,448 - 34,219,223 (+)NCBI
Rnor_6.01436,689,075 - 36,755,353 (+)NCBI
Rnor_5.01436,514,023 - 36,582,331 (+)NCBI
Sequence:
RefSeq Acc Id: XR_010057350
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81434,504,074 - 34,566,269 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178525 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250951 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ADV57650 (Get FASTA)   NCBI Sequence Viewer  
  EDL89948 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002879
  ENSRNOP00000080787
GenBank Protein F1M625 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001178525   ⟸   NM_001191596
- UniProtKB: G8ACC6 (UniProtKB/Swiss-Prot),   F1M625 (UniProtKB/TrEMBL),   A6JD26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250951   ⟸   XM_006250889
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2V1 (UniProtKB/TrEMBL),   A0A8I5ZTT8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002879   ⟸   ENSRNOT00000002879
Ensembl Acc Id: ENSRNOP00000072387   ⟸   ENSRNOT00000083100
Ensembl Acc Id: ENSRNOP00000080787   ⟸   ENSRNOT00000097061
Ensembl Acc Id: ENSRNOP00000080661   ⟸   ENSRNOT00000112025
Ensembl Acc Id: ENSRNOP00000086106   ⟸   ENSRNOT00000119848
Protein Domains
USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M625-F1-model_v2 AlphaFold F1M625 1-366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699288
Promoter ID:EPDNEW_R9813
Type:multiple initiation site
Name:Usp46_1
Description:ubiquitin specific peptidase 46
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01436,687,092 - 36,687,152EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564808 AgrOrtholog
BioCyc Gene G2FUF-15902 BioCyc
Ensembl Genes ENSRNOG00000002106 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000002879 ENTREZGENE
  ENSRNOT00000097061 ENTREZGENE
Gene3D-CATH Cysteine proteinases UniProtKB/Swiss-Prot
InterPro Papain_like_cys_pep_sf UniProtKB/Swiss-Prot
  Peptidase_C19 UniProtKB/Swiss-Prot
  Peptidase_C19_UCH UniProtKB/Swiss-Prot
  USP_CS UniProtKB/Swiss-Prot
  USP_dom UniProtKB/Swiss-Prot
KEGG Report rno:289584 UniProtKB/Swiss-Prot
NCBI Gene 289584 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 46 UniProtKB/Swiss-Prot
Pfam UCH UniProtKB/Swiss-Prot
PhenoGen Usp46 PhenoGen
PROSITE USP_1 UniProtKB/Swiss-Prot
  USP_2 UniProtKB/Swiss-Prot
  USP_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002106 RatGTEx
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot
UniProt A0A0G2K2V1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZQ40_RAT UniProtKB/TrEMBL
  A0A8I5ZTT8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A5E0_RAT UniProtKB/TrEMBL
  A0A8L2PZX2_RAT UniProtKB/TrEMBL
  A6JD26 ENTREZGENE, UniProtKB/TrEMBL
  F1M625 ENTREZGENE
  G8ACC6 ENTREZGENE
  UBP46_RAT UniProtKB/Swiss-Prot
UniProt Secondary G8ACC6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Usp46  ubiquitin specific peptidase 46  RGD1564808_predicted  similar to ubiquitin specific protease 46 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564808_predicted  similar to ubiquitin specific protease 46 (predicted)  LOC289584  similar to ubiquitin specific protease 46  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC289584  similar to ubiquitin specific protease 46      Symbol and Name status set to provisional 70820 PROVISIONAL