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Gene: Zfp341 (zinc finger protein 341) Rattus norvegicus

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Symbol:

Zfp341

Name:

zinc finger protein 341

RGD ID:

1564726

Description:

Predicted to enable DNA-binding transcription activator activity and chromatin insulator sequence binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in chromosome. Human ortholog(s) of this gene implicated in hyper IgE recurrent infection syndrome 3. Orthologous to human ZNF341 (zinc finger protein 341); INTERACTS WITH bisphenol A; 1,2-dichloroethane (ortholog); 2,2',4,4'-Tetrabromodiphenyl ether (ortholog).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AABR07054367.1; LOC296300; LRRGT00145; similar to zinc finger protein 341; Zfp966; zinc finger protein 966; Znf341

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNF341 (zinc finger protein 341)	HGNC	Ensembl, HomoloGene, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Zfp341 (zinc finger protein 341)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Znf341 (zinc finger protein 341)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZNF341 (zinc finger protein 341)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNF341 (zinc finger protein 341)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Znf341 (zinc finger protein 341)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZNF341 (zinc finger protein 341)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNF341 (zinc finger protein 341)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Znf341 (zinc finger protein 341)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ZNF341 (zinc finger protein 341)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ZNF341 (zinc finger protein 341)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zfp341 (zinc finger protein 341)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zfp341 (zinc finger protein 341)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	znf341 (zinc finger protein 341)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	znf341 (zinc finger protein 341)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	znf341	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	znf341	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	163,582,937 - 163,616,448 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	163,579,298 - 163,616,446 (+)	Ensembl				GRCr8
mRatBN7.2	3	143,122,699 - 143,156,250 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	143,119,093 - 143,156,249 (+)	Ensembl				mRatBN7.2
Rnor_6.0	3	150,114,853 - 150,172,425 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	150,135,821 - 150,153,775 (+)	NCBI			rn6	Rnor6.0
Rnor_5.0	3	156,511,320 - 156,544,251 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	145,086,839 - 145,105,846 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	141,855,266 - 141,888,862 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

glutathione synthetase deficiency (ISO)

glutatione synthetase deficiency with 5-oxoprolinuria (ISO)

hyper IgE recurrent infection syndrome 3 (ISO)

hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase (ISO)

long QT syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

cannabidiol (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

ethanol (ISO)

methapyrilene (ISO)

methyl methanesulfonate (ISO)

okadaic acid (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

chromosome (IBA)

nucleus (IEA,ISO)

Molecular Function

chromatin insulator sequence binding (IBA)

DNA binding (IEA,ISO)

DNA-binding transcription activator activity (IEA,ISO)

DNA-binding transcription factor activity (IEA)

metal ion binding (IEA)

protein binding (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:29907690

Genomics

Comparative Map Data

Zfp341
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	163,582,937 - 163,616,448 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	163,579,298 - 163,616,446 (+)	Ensembl				GRCr8
mRatBN7.2	3	143,122,699 - 143,156,250 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	143,119,093 - 143,156,249 (+)	Ensembl				mRatBN7.2
Rnor_6.0	3	150,114,853 - 150,172,425 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	150,135,821 - 150,153,775 (+)	NCBI			rn6	Rnor6.0
Rnor_5.0	3	156,511,320 - 156,544,251 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	145,086,839 - 145,105,846 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	141,855,266 - 141,888,862 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

ZNF341
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	33,731,996 - 33,792,269 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	33,731,657 - 33,792,269 (+)	Ensembl			hg38	GRCh38
GRCh37	20	32,319,802 - 32,380,075 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	31,783,469 - 31,843,736 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	31,783,468 - 31,843,736	NCBI
Celera	20	29,072,525 - 29,132,795 (+)	NCBI		Celera
Cytogenetic Map	20	q11.22	NCBI
HuRef	20	29,105,231 - 29,164,875 (+)	NCBI		HuRef
CHM1_1	20	32,221,188 - 32,281,398 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	35,458,351 - 35,518,627 (+)	NCBI		T2T-CHM13v2.0

Zfp341
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	154,453,736 - 154,488,741 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	154,455,217 - 154,488,741 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	154,611,816 - 154,646,821 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	154,613,297 - 154,646,821 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	154,439,104 - 154,472,553 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	154,304,809 - 154,338,258 (+)	NCBI		MGSCv36	mm8
MGSCv36	2	155,440,850 - 155,474,283 (+)	NCBI		MGSCv36	mm8
Celera	2	160,541,217 - 160,566,229 (+)	NCBI		Celera
Cytogenetic Map	2	H1	NCBI
cM Map	2	76.79	NCBI

Znf341
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	27,537,917 - 27,583,711 (-)	Ensembl
ChiLan1.0	NW_004955422	27,537,293 - 27,583,713 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZNF341
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	39,418,445 - 39,483,467 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	39,411,547 - 39,476,569 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	30,018,348 - 30,079,721 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	31,166,374 - 31,218,282 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	31,164,597 - 31,218,282 (+)	Ensembl			panPan2	panpan1.1

ZNF341
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	22,937,990 - 22,984,646 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	22,938,093 - 22,982,367 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	22,583,240 - 22,629,894 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	23,624,867 - 23,671,552 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	23,624,950 - 23,670,551 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	22,917,225 - 22,963,979 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	23,010,745 - 23,057,362 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	23,488,954 - 23,494,847 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0
UU_Cfam_GSD_1.0	24	23,441,838 - 23,462,455 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Znf341
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	171,894,730 - 171,933,200 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936561	6,816,328 - 6,851,452 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936561	6,816,349 - 6,851,609 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF341
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	37,224,048 - 37,280,118 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	37,223,959 - 37,272,263 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	42,186,197 - 42,200,711 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNF341
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	38,020,915 - 38,081,559 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	38,028,765 - 38,080,814 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	88,799,998 - 88,860,135 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znf341
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624842	5,519,035 - 5,565,613 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624842	5,518,327 - 5,565,661 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Zfp341
198 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	55
Count of miRNA genes:	52
Interacting mature miRNAs:	54
Transcripts:	ENSRNOT00000047286
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
1582233	Insul10	Insulin level QTL 10	5.4	0.0015	blood insulin amount (VT:0001560)	serum insulin level times blood glucose level (CMO:0002040)	3	133259579	178259579	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161492708	189428310	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
61335	Bp20	Blood pressure QTL 20	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161799493	176036425	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	133134628	178134628	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	161799270	187311134	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	141508991	166376254	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	125116475	170116475	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	122395989	167395989	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	141508991	177728348	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	131036586	176036586	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	137114333	182114333	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	131036586	176036586	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	160357340	167835660	Rat

Markers in Region

RH130998

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	143,155,893 - 143,156,110 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	150,172,069 - 150,172,285	NCBI	Rnor6.0
Rnor_5.0	3	156,543,895 - 156,544,111	UniSTS	Rnor5.0
RGSC_v3.4	3	145,123,667 - 145,123,883	UniSTS	RGSC3.4
Celera	3	141,888,506 - 141,888,722	UniSTS
RH 3.4 Map	3	1266.2	UniSTS
Cytogenetic Map	3	q41	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
7	1	18	48	67	138	95	11	47	36	32	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001430392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001430393	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106692	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY539896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000047286 ⟹ ENSRNOP00000043308

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	163,583,036 - 163,616,446 (+)	Ensembl
mRatBN7.2 Ensembl	3	143,119,093 - 143,156,249 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000172805 ⟹ ENSRNOP00000111635

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	163,579,298 - 163,598,942 (+)	Ensembl

RefSeq Acc Id:

XM_008762405 ⟹ XP_008760627

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	163,582,937 - 163,616,448 (+)	NCBI
mRatBN7.2	3	143,122,708 - 143,156,250 (+)	NCBI
Rnor_6.0	3	150,114,853 - 150,172,425 (+)	NCBI

Sequence:

show sequence

AATGCTTGCGTAGCCCCCGCTTCGACTCCCCGGGCGGCGGCAGCTCCAAGATGGCGCAGGCGAT
CTTCGAGGCCCTGGAGGGAATGGACAATCAAACTGTTCTGGCTGTCCAGTCCTTGTTGGATGGC
CAAGGAGCAGTCCCTGATCCAACAGGGCAAGGTGTAAGTGCACCGCCTGCCATCCAGCCACTGG
ACGATGAGGATGTCTTTCTCTGCGGGAAGTGTAAGAAGCAATTCAACTCATTGCCGGCCTTCAT
GACCCACAAGCGTGAGCAGTGCCAGGGGAACGCCCCTGCTCTGGCTACGGTCTCCCTGGCTACC
AACAGCATCTACACACCTTCCGCAGCACCTGCTGCCGTCCAGCAGGCCCCGCCTCCTGCCAACC
GCCAGATCTCCACATACATCACAGTGCCCCCATCCCCACTGATCCAGACCCTGGTGCAAGGGAA
CATCCTGGTGAGCGATGACGTGCTCATGTCTGCCATGTCAGCCTTCACCTCCCTGGACCAGCCA
ATGCCTCAAGGACCCTCCCCTGTGCAGAACAGCTTGAACATGCATCCTGTGCCCAATTACCTCA
CCCAGCCTCCACCCCCTCCTCCACCTCCACCCCTCGCCCCGCCCAGCCTCCCTNNCCCACCCCA
GACCCTGGGTCCTTCTGGGCGCTCCAACCCTGTTGGGAACAGCGTGGTGGAGGTGTACAGTGCT
GCTGCTCCCATGGCGGGGAACGGAACGGTGGACATTCAGGCACTGGGGATGCAGCCATACCCAC
CCCTGGAGGTGCCAAATCAGTGTGTGGAGGCTCCAGTGTACCCCACACCCCCGGTGTACAGCCC
TGGCAAGCAGGAATTCAAACCCAAAGGACCCAACTCCACTGCCCCCATGACCAGTGCAACTGGG
AGCACGGTGGCCACCTTTGACCCCCCACCGACGCTGAAGACCAGACGTGCTAAAGGTGCCAGTG
GACTCCCAGAAGCTGCAGGGAAGCCAAAGGCTCAGAAACTCAAGTGCTCCTACTGTGACAAGTC
GTTCACCAAAAACTTTGACCTTCAGCAGCACGTCCGAAGCCACACGGGGGAAAAGCCCTTCCAG
TGCATTGCATGTGGCCGTGCCTTTGCCCAGAAGTCTAACGTCAAGAAGCACATGCAAACTCATA
AGGTGTGGCCTCCAGGGAGAAGTGGTGGCACAGTTTCCCGAAACTCTGTGACGGTACAAGTCAT
GGCTTTGAACCCCAACAGGCAAGAGGAGGAAGACACAGGGTTGGGTCAGTCCCTGTCCAGCACC
ACGCAGCCCCAGGCCTTGCCCACGGCAGGAGAGGAGGAAGGCAACAAGCCAGAGGCCAAGCAGG
TGGTTCTCATCGACAGCTCCTACCTGTGTCAGTTCTGCCCCAGCAAGTTCAGCACCTACTTTCA
GCTCAAGTCCCACATGATCCAGCACAAGAAGGAGCAGGTGTACAAGTGCGTGGTCAAAAGCTGT
GCCCAGATGTTCCCCAAGCTGGACACCTTTCTGGAGCACATCAGAAGCCACCAGGAGGAGCTGA
GCTATCGCTGCCATCTCTGTAGCAAGGACTTCCCCTCCCTGTATGACCTGGGCGTGCACCAGTA
CTCTCACAGTCTCCTGCCGCAGCACAGCCCCAGGAAGGACAGCACCGTCTACAAGTGTGTCAAG
TGTGTCAACAAATACTCCACCCCTGAGGCCTTGGAGCACCACGTACAGACGGCCACTCATAGCT
TCCCCTGCCCACACTGCCAGAAGGTCTTCCCTTGTGAACGCTACCTGCGGCGTCACTTACCCAC
CCACGGCAGTGGTGGCCGGTTCAGGTGCCAGATCTGTAAGAAGTTCTTCCGGAAGGAGCACTAC
CTCAAGCTGCACGCCCACATCCACTCAGGTGAGAAGCCCTACAAATGCTCAGTGTGTGAGTCTG
CGTTCAACCGCAAAGACAAGCTCAAGAGACACATGCTGATCCACGAGCCCTTCAAGAAGTACAA
ATGTCCCTTCTCGATGCACACAGGCTGCAGTAAGGAGTTCAACCGGCAGGACAAGCTGAAAGCT
CACATCCTCTCCCACGCTGGCCTGAAGCTCCACAAGTGTGGGCTGTGCAGCAAGTCCTTCAGCC
GGCGAGCCCACTTGGCAGAGCACCAACACGCTCACACGGGCAACTACAAGTTCCGCTGCGCAGG
CTGTGCCAAGGGCTTCTCACGACACAAATACCTCAAGGATCACCGCTGCCGCCTGGGCCCCTCG
AAGGACAAGGACCTGCAAACCCGGCGGCCTCCCCGGAGGAGAGCAACAGCTCGTGGTGCTGGCA
ACATCGCCAGCGTGCATAAGGAGGAGAACCCCTTGCCGGATCCGCTGGGGCTGGAGGAGCTAAA
GGCCGCAGGACCCTCTCCTGAGGCTGCCCCTGGCAAGCCACCCTTTGAGCAGGACGCTGTGTTG
TCCATTGTGGTGGGCGGGGACCCGGAGCTCGTGGTGCCCGGTCACACTGAGGGTCTGGGCTCCA
ACCTGGCACTTGCCGAGTTGCAGGCTGGAACCGAGGGAGGGTGTGCCATGCTCGCTGTCCCAGT
CTACATCCAGGCCTCAGAGTAACCGAGCTGGACTTGCTGAAAGTGGGGTGGGGGAAAAGTGCAT
TGGCCCAATCCCTTTTGGAAGTTACTGTATCAACCTTGTTGGCTGCTGTCCTCCTCCGCCCCTC
GATTGTCTGGAGAAACCTGCAGCACTTATAGGGTCTGAGGCAGGCGCCATCGCTCCAGGGCATA
GCAGTGGTAAGAGACAAGGCCAGAGCATGAAGTGCCCAGGGGGCTGGCTGATGATGGAGGCTGG
TACTTGGGCATCCTCCAAGAGAAGGTAGGGTGATCCCACCCACCTATCCAGGTTACCTGGGGTG
GCCTCAGGTCGTGCTGCCATTTGGGATGCTAGCTGGATGTGGCTGGAGTCCTTGTATGTTGAAC
CATTACTAAAACACTTCCCAATGAGTGGGTCCTCTGAGGACTGTATGAGGTGCGTATGTGAGAG
GCACTCAGCCCAGGGCTAAGGCTGTAGCTACCAGCCAGCCCTTGGCTTCAGACTCACCAGTGTG
ATCTGAGCAGGGCACTTAACCTCTTTCTGCTCAGAGCTCCTCACCTGTACAACAGGACTTCATA
CAGCACTACCTCCTAGAGTGTCCCGGGGACATAGTCTGCTACGATGTGCAAAGGGCTGGGCAGA
GTACCCATGACCTGGAAAGTGCTCAGTAAATCTCAATAAATGTTTTTACCGACGA

hide sequence

RefSeq Acc Id:

XM_039106691 ⟹ XP_038962619

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	163,582,937 - 163,616,448 (+)	NCBI
mRatBN7.2	3	143,122,704 - 143,156,250 (+)	NCBI

RefSeq Acc Id:

XM_039106692 ⟹ XP_038962620

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	163,582,937 - 163,616,448 (+)	NCBI
mRatBN7.2	3	143,122,701 - 143,156,250 (+)	NCBI

RefSeq Acc Id:

XM_039106694 ⟹ XP_038962622

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	163,595,421 - 163,616,448 (+)	NCBI
mRatBN7.2	3	143,135,221 - 143,156,250 (+)	NCBI

RefSeq Acc Id:

XM_063285100 ⟹ XP_063141170

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	163,592,985 - 163,616,448 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001417321	(Get FASTA)	NCBI Sequence Viewer
	NP_001417322	(Get FASTA)	NCBI Sequence Viewer
	XP_008760627	(Get FASTA)	NCBI Sequence Viewer
	XP_038962619	(Get FASTA)	NCBI Sequence Viewer
	XP_038962620	(Get FASTA)	NCBI Sequence Viewer
	XP_038962622	(Get FASTA)	NCBI Sequence Viewer
	XP_063141170	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88839	(Get FASTA)	NCBI Sequence Viewer
	AAS66236	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000043308
	ENSRNOP00000043308.4

RefSeq Acc Id:

XP_008760627 ⟸ XM_008762405

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAQAIFEALEGMDNQTVLAVQSLLDGQGAVPDPTGQGVSAPPAIQPLDDEDVFLCGKCKKQFNS
LPAFMTHKREQCQGNAPALATVSLATNSIYTPSAAPAAVQQAPPPANRQISTYITVPPSPLIQT
LVQGNILVSDDVLMSAMSAFTSLDQPMPQGPSPVQNSLNMHPVPNYLTQPPPPPPPPPLAPPSL
PXPPQTLGPSGRSNPVGNSVVEVYSAAAPMAGNGTVDIQALGMQPYPPLEVPNQCVEAPVYPTP
PVYSPGKQEFKPKGPNSTAPMTSATGSTVATFDPPPTLKTRRAKGASGLPEAAGKPKAQKLKCS
YCDKSFTKNFDLQQHVRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGRSGGTVSRNSV
TVQVMALNPNRQEEEDTGLGQSLSSTTQPQALPTAGEEEGNKPEAKQVVLIDSSYLCQFCPSKF
STYFQLKSHMIQHKKEQVYKCVVKSCAQMFPKLDTFLEHIRSHQEELSYRCHLCSKDFPSLYDL
GVHQYSHSLLPQHSPRKDSTVYKCVKCVNKYSTPEALEHHVQTATHSFPCPHCQKVFPCERYLR
RHLPTHGSGGRFRCQICKKFFRKEHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHEP
FKKYKCPFSMHTGCSKEFNRQDKLKAHILSHAGLKLHKCGLCSKSFSRRAHLAEHQHAHTGNYK
FRCAGCAKGFSRHKYLKDHRCRLGPSKDKDLQTRRPPRRRATARGAGNIASVHKEENPLPDPLG
LEELKAAGPSPEAAPGKPPFEQDAVLSIVVGGDPELVVPGHTEGLGSNLALAELQAGTEGGCAM
LAVPVYIQASE

hide sequence

RefSeq Acc Id:	XP_038962620 ⟸ XM_039106692
- Peptide Label:	isoform X3
- UniProtKB:	A6KI01 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038962619 ⟸ XM_039106691
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038962622 ⟸ XM_039106694
- Peptide Label:	isoform X5

Ensembl Acc Id:

ENSRNOP00000043308 ⟸ ENSRNOT00000047286

RefSeq Acc Id:	XP_063141170 ⟸ XM_063285100
- Peptide Label:	isoform X4
- UniProtKB:	A6KI01 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000111635 ⟸ ENSRNOT00000172805

Protein Domains

C2H2-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F7ETL6-F1-model_v2	AlphaFold	F7ETL6	1-428	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564726	AgrOrtholog
BioCyc Gene	G2FUF-47166	BioCyc
Ensembl Genes	ENSRNOG00000017086	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000047286	ENTREZGENE
	ENSRNOT00000047286.4	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7125614	IMAGE-MGC_LOAD
InterPro	C2H2-ZF_domain	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
MGC_CLONE	MGC:105872	IMAGE-MGC_LOAD
NCBI Gene	296300	ENTREZGENE
PANTHER	C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED	UniProtKB/TrEMBL
	FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED	UniProtKB/TrEMBL
Pfam	zf-C2H2	UniProtKB/TrEMBL
	zf-C2H2_6	UniProtKB/TrEMBL
PhenoGen	Zfp341	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017086	RatGTEx
SMART	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/TrEMBL
UniProt	A6KI01	ENTREZGENE, UniProtKB/TrEMBL
	F7ETL6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Zfp341	zinc finger protein 341	AABR07054367.1		Data merged from RGD:15003446	737654	PROVISIONAL
2019-11-08	AABR07054367.1				Symbol and Name status set to provisional	45752	PROVISIONAL
2012-11-27	Znf341	zinc finger protein 341	Zfp966	zinc finger protein 966	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-11-27	Zfp341	zinc finger protein 341	Znf341	zinc finger protein 341	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-09-17	Zfp966	zinc finger protein 966	LOC296300	similar to zinc finger protein 341	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	LOC296300	similar to zinc finger protein 341			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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