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Gene: Nup62cl (nucleoporin 62 C-terminal like) Rattus norvegicus

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Symbol:

Nup62cl

Name:

nucleoporin 62 C-terminal like

RGD ID:

1564353

Description:

Predicted to enable phospholipid binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in RNA export from nucleus and protein import into nucleus. Predicted to be part of nuclear pore central transport channel. Orthologous to human NUP62CL (nucleoporin 62 C-terminal like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC300923; RGD1564353; similar to Nucleoporin 62

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NUP62CL (nucleoporin 62 C-terminal like)	HGNC	Ensembl, NCBI, Panther
Mus musculus (house mouse):	Nup62cl (nucleoporin 62 C-terminal like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nup62cl (nucleoporin 62 C-terminal like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NUP62CL (nucleoporin 62 C-terminal like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NUP62CL (nucleoporin 62 C-terminal like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nup62cl (nucleoporin 62 C-terminal like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NUP62CL (nucleoporin 62 C-terminal like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NUP62CL (nucleoporin 62 C-terminal like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nup62cl (nucleoporin 62 C-terminal like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NUP62 (nucleoporin 62)	HGNC	Panther
Alliance orthologs ³
Homo sapiens (human):	NUP62CL (nucleoporin 62 C-terminal like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|PhylomeDB)
Mus musculus (house mouse):	Nup62cl (nucleoporin 62 C-terminal like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	NSP1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nup62	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	npp-11	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	108,457,043 - 108,513,525 (-)	NCBI		GRCr8
mRatBN7.2	X	103,668,458 - 103,724,957 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	103,668,455 - 103,724,081 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	X	111,333,274 - 111,390,023 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	111,334,252 - 111,365,849 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	53,207,455 - 53,264,220 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	127,752,322 - 127,812,950 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	44,203,467 - 44,259,295 (+)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

Charcot-Marie-Tooth disease type X (ISO)

factor VIII deficiency (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbamazepine (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

diiodine (ISO)

dorsomorphin (ISO)

Enterolactone (ISO)

ethanol (ISO)

methotrexate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

oxaliplatin (EXP)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

quercetin (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

thalidomide (ISO)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

torcetrapib (ISO)

triclosan (ISO)

valproic acid (EXP,ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein import into nucleus (IBA)

RNA export from nucleus (IBA)

Cellular Component

nuclear pore central transport channel (IBA)

Molecular Function

phospholipid binding (IBA)

protein binding (ISO)

structural constituent of nuclear pore (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15970630

Genomics

Comparative Map Data

Nup62cl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	108,457,043 - 108,513,525 (-)	NCBI		GRCr8
mRatBN7.2	X	103,668,458 - 103,724,957 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	103,668,455 - 103,724,081 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	X	111,333,274 - 111,390,023 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	111,334,252 - 111,365,849 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	53,207,455 - 53,264,220 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	127,752,322 - 127,812,950 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	44,203,467 - 44,259,295 (+)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

NUP62CL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	107,123,427 - 107,206,433 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	107,123,427 - 107,206,433 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	106,366,657 - 106,449,663 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	106,253,358 - 106,336,200 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	X	106,837,965 - 106,921,027 (-)	NCBI		Celera
Cytogenetic Map	X	q22.3	NCBI
HuRef	X	95,994,426 - 96,076,159 (-)	NCBI		HuRef
CHM1_1	X	106,277,530 - 106,360,560 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	105,559,960 - 105,642,842 (-)	NCBI		T2T-CHM13v2.0

Nup62cl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	138,907,551 - 138,963,456 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	138,907,554 - 138,963,461 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	140,006,802 - 140,062,707 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	140,006,805 - 140,062,712 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	136,542,212 - 136,597,107 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	135,354,037 - 135,408,909 (-)	NCBI		MGSCv36	mm8
Celera	X	123,269,854 - 123,324,869 (-)	NCBI		Celera
Cytogenetic Map	X	F1	NCBI
cM Map	X	61.35	NCBI

Nup62cl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955490	8,842,889 - 8,860,885 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955490	8,807,866 - 8,904,153 (+)	NCBI	ChiLan1.0	ChiLan1.0

NUP62CL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	106,605,716 - 106,722,143 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	106,609,317 - 106,725,744 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	96,222,802 - 96,300,219 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	106,600,838 - 106,676,569 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	106,600,819 - 106,638,256 (-)	Ensembl	panpan1.1		panPan2

NUP62CL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	80,708,829 - 80,787,441 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	80,729,667 - 80,784,034 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	66,827,950 - 66,922,117 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	82,352,349 - 82,446,668 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	79,815,275 - 79,909,439 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	81,526,810 - 81,620,971 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	81,318,837 - 81,412,574 (-)	NCBI		UU_Cfam_GSD_1.0

Nup62cl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	80,077,312 - 80,154,636 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936499	7,503,475 - 7,579,453 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NUP62CL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	87,601,042 - 87,630,253 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	87,578,656 - 87,658,296 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	101,950,958 - 102,030,618 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NUP62CL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	94,952,017 - 95,033,089 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	94,951,636 - 94,998,052 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	20,032,182 - 20,116,664 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nup62cl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624803	9,424,628 - 9,487,626 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624803	9,391,282 - 9,487,066 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nup62cl
136 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	144
Count of miRNA genes:	94
Interacting mature miRNAs:	124
Transcripts:	ENSRNOT00000066497
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	93956491	138956491	Rat
1598856	Memor1	Memory QTL 1	1.9		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	X	103312877	148312877	Rat
1598809	Memor15	Memory QTL 15	4.4		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	103312877	148312877	Rat
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	100567703	150256146	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	65612192	120568734	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	41304447	112935181	Rat
724551	Glom1	Glomerulus QTL 1	2.8	0.0004	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	X	75294106	120294106	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat

Markers in Region

AI179798

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	103,668,657 - 103,668,809 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	111,333,477 - 111,333,628	NCBI	Rnor6.0
Rnor_5.0	3	53,263,866 - 53,264,017	UniSTS	Rnor5.0
RGSC_v3.4	X	127,752,525 - 127,752,676	UniSTS	RGSC3.4
Celera	3	44,258,941 - 44,259,092	UniSTS
RH 3.4 Map	7	1122.91	UniSTS
Cytogenetic Map	X	q35	UniSTS

AU049450

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	103,719,292 - 103,719,485 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	111,384,962 - 111,385,154	NCBI	Rnor6.0
Rnor_5.0	3	53,212,340 - 53,212,532	UniSTS	Rnor5.0
RGSC_v3.4	X	127,808,138 - 127,808,330	UniSTS	RGSC3.4
Celera	3	44,208,851 - 44,209,043	UniSTS
Cytogenetic Map	X	q35	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
7	2	29	107	72	73	47	11	47	2	147	55	93	36	60	26

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001427605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006224456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006224457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006224460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039100269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC160918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000088979 ⟹ ENSRNOP00000075626

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	103,668,455 - 103,724,081 (-)	Ensembl
Rnor_6.0 Ensembl	X	111,334,252 - 111,365,849 (-)	Ensembl

RefSeq Acc Id:

NM_001427605 ⟹ NP_001414534

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	108,457,883 - 108,512,665 (-)	NCBI

RefSeq Acc Id:

XM_006234254 ⟹ XP_006234316

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	108,457,043 - 108,512,880 (-)	NCBI
mRatBN7.2	X	103,669,293 - 103,724,191 (-)	NCBI
Rnor_6.0	X	111,333,274 - 111,389,404 (-)	NCBI
Rnor_5.0	3	53,207,455 - 53,264,220 (+)	NCBI

Sequence:

show sequence

ATCCCAGCGCGTCCCGTTCCGTGTCTATGGCCGCCCTTTCTAGTTAAGTAGGTCGACAGGGGAT
CCGTCGCTGCTGGCTCCTGGGAGTTCTCCGCTTCTCCGCTAGAGTAGCTCGGAGTACGGGCCCG
CCCCCTTCTCTCGGACTGCCTCTCTCTCGGCCTCCGCCTTCACTTTGTAGACGGGATAGCGAGC
TTGCACAGCCGAGGAGGTCTACTCCAAGATCTACTCTGTGGACACCACTGAGATTTTGAGCACT
AAGATGTTCCCTTCAACACCATATGTTCCTGCCTGCATGGCTTCTCAGGAACTCTCATCCACAA
CCTCAACAACTACAACTACCACGGTCACCACCAATACCACTACCACAATTACAAGTGGCTTCAA
CCTGTATCTGACACCACCTGCATCATCACCATGGCTTAACAACACTGGCTTAATCAATATGGCT
TCTCTGCCTTCTACCATGACCGTGAACTCAATAGTGACTCCTGTGATGACATATGGTCCTCTGG
ATAGCATGGTGAACAACTGGCACTATCAGCTTCAAGAACAAGAAAAACACTACTTTTATCAGGC
TCACCAATTCAATGTTTGGAACCATGCACTGATTGAGACCAGTAATGAGATTGCTCTTTTGCAC
AACGAAGTGGAAAGAGTGAAACGGGATCAGAGCAGGTTGGAACAAGAATTGGATCTTATCCTGC
TCCAGCAGAAGGAACTGGAACATACCTTGGCTCCCATAGAGGAGTTTTTGAAGGAGCAGAATGG
TCCTCTTAAACTGCTGTATGTGAATAAGGAGTATGAGATGATTTATAGACTGGCTGAAGTCATA
GATGCTGACCTGAAAAGGATGTCTCAAGATCTCAAGGACATCATTATTTACCTGAATTCAGTGA
TTCGTCCTGCTGATGCTTCTGAACCACTGGAGCAGATCTGCAGGATTCTGAGTGCTCATCTGGA
GTCTCTGCAGTGGATCAGCCATAATTCAGGCATAATGCATAAGAAGGTAGAGGAGGTTGCAAAG
GCATTTGAGGAGTACCGTCGCAAGGGGCAAGATGCCATGAATGTTGCCTTTGAGTAACTGAAGA
TACCATGAAGAAGATTGCCTTTGAATAACTATCGCTCCAAATTACTCCTTTTGGATTATTCATT
AACCCTAAATTCTGATGATATTAAATAGAGTAGTATTTTCAGTTACTACTTAATTTTTGATTGC
AATAATTTGTGCATGTGTTTTTCATTTAGATAATGTGAAGAGAAGTGTGCTTTTTTTCTTTCAG
AATGGAATAAAGTCTGGACACAGTGATAGTAATGCCTACACAGAATTAAGTAACCCCCTTGTGG
GTATTGATTCTGTGTGTATAATACCTGTCTTATTCAGATTCTGCATACTGTCACTAGTGCACAT
CAACTTCTTACTGCAGCTTAATTGTGGCCAGTTGTTTGCCAAAATGCACGTGTCACCCAGTCTT
TACTGGGTGTTTGTGGCCGTTCATAGAAAGTGCTGGATCCTGTAAAGTCTCAAGTGAAATTTAC
TATCTACTCTGAGATATAATTTTACCTGTTAAGGGAAATATGGGCAATGAAAAAACAAGTGTAT
GACAAATTACAGCAAGTGTCTTTCAGGAGCTCACAGATGATAATGCGGTTTTATGGATTAGAGA
TTTCATTTGGGCTTTGATTTTTCTAATGGTACTAGAGATCAAACCATGTGCCACACTCTTGGAT
AATATACCCAGCACTGTATTATGGGTAAGGTCCAATGATCCACTTACTTTTGACAATATACCTC
AGTGCTTTTGTTTCTAAATCAAGATCTCACTGTAGCCTATGCTGGCTTGGAACTTACAATCCTC
CTGCCTCAGTTTTACAAGTGCCACTATACCTAGGTATCCTGGTGATTTTTGTCATTTGTTTTGT
TTTAGCATATGATTTAGTTTTCTGTCTGTAAAGAAAAAAGCTGCCTTCTTAGCTCTAAAACATC
TTCATCTCTTGTGTTTCATCCAAGTTGCTAATAATGATGTCCTAAAAATGAAAATAAAGTGATT
AAAAGGTT

hide sequence

RefSeq Acc Id:

XM_006234255 ⟹ XP_006234317

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	108,457,043 - 108,513,525 (-)	NCBI
mRatBN7.2	X	103,669,293 - 103,724,957 (-)	NCBI
Rnor_6.0	X	111,333,274 - 111,390,023 (-)	NCBI
Rnor_5.0	3	53,207,455 - 53,264,220 (+)	NCBI

Sequence:

show sequence

TCCTCCTCCATTTCCCAATTAAGGTTTGCTGGTCCAGAATTAATACTGCTTGTTCACATAAAAC
GGAAGGTCTACTCCAAGATCTACTCTGTGGACACCACTGAGATTTTGAGCACTAAGATGTTCCC
TTCAACACCATATGTTCCTGCCTGCATGGCTTCTCAGGAACTCTCATCCACAACCTCAACAACT
ACAACTACCACGGTCACCACCAATACCACTACCACAATTACAAGTGGCTTCAACCTGTATCTGA
CACCACCTGCATCATCACCATGGCTTAACAACACTGGCTTAATCAATATGGCTTCTCTGCCTTC
TACCATGACCGTGAACTCAATAGTGACTCCTGTGATGACATATGGTCCTCTGGATAGCATGGTG
AACAACTGGCACTATCAGCTTCAAGAACAAGAAAAACACTACTTTTATCAGGCTCACCAATTCA
ATGTTTGGAACCATGCACTGATTGAGACCAGTAATGAGATTGCTCTTTTGCACAACGAAGTGGA
AAGAGTGAAACGGGATCAGAGCAGGTTGGAACAAGAATTGGATCTTATCCTGCTCCAGCAGAAG
GAACTGGAACATACCTTGGCTCCCATAGAGGAGTTTTTGAAGGAGCAGAATGGTCCTCTTAAAC
TGCTGTATGTGAATAAGGAGTATGAGATGATTTATAGACTGGCTGAAGTCATAGATGCTGACCT
GAAAAGGATGTCTCAAGATCTCAAGGACATCATTATTTACCTGAATTCAGTGATTCGTCCTGCT
GATGCTTCTGAACCACTGGAGCAGATCTGCAGGATTCTGAGTGCTCATCTGGAGTCTCTGCAGT
GGATCAGCCATAATTCAGGCATAATGCATAAGAAGGTAGAGGAGGTTGCAAAGGCATTTGAGGA
GTACCGTCGCAAGGGGCAAGATGCCATGAATGTTGCCTTTGAGTAACTGAAGATACCATGAAGA
AGATTGCCTTTGAATAACTATCGCTCCAAATTACTCCTTTTGGATTATTCATTAACCCTAAATT
CTGATGATATTAAATAGAGTAGTATTTTCAGTTACTACTTAATTTTTGATTGCAATAATTTGTG
CATGTGTTTTTCATTTAGATAATGTGAAGAGAAGTGTGCTTTTTTTCTTTCAGAATGGAATAAA
GTCTGGACACAGTGATAGTAATGCCTACACAGAATTAAGTAACCCCCTTGTGGGTATTGATTCT
GTGTGTATAATACCTGTCTTATTCAGATTCTGCATACTGTCACTAGTGCACATCAACTTCTTAC
TGCAGCTTAATTGTGGCCAGTTGTTTGCCAAAATGCACGTGTCACCCAGTCTTTACTGGGTGTT
TGTGGCCGTTCATAGAAAGTGCTGGATCCTGTAAAGTCTCAAGTGAAATTTACTATCTACTCTG
AGATATAATTTTACCTGTTAAGGGAAATATGGGCAATGAAAAAACAAGTGTATGACAAATTACA
GCAAGTGTCTTTCAGGAGCTCACAGATGATAATGCGGTTTTATGGATTAGAGATTTCATTTGGG
CTTTGATTTTTCTAATGGTACTAGAGATCAAACCATGTGCCACACTCTTGGATAATATACCCAG
CACTGTATTATGGGTAAGGTCCAATGATCCACTTACTTTTGACAATATACCTCAGTGCTTTTGT
TTCTAAATCAAGATCTCACTGTAGCCTATGCTGGCTTGGAACTTACAATCCTCCTGCCTCAGTT
TTACAAGTGCCACTATACCTAGGTATCCTGGTGATTTTTGTCATTTGTTTTGTTTTAGCATATG
ATTTAGTTTTCTGTCTGTAAAGAAAAAAGCTGCCTTCTTAGCTCTAAAACATCTTCATCTCTTG
TGTTTCATCCAAGTTGCTAATAATGATGTCCTAAAAATGAAAATAAAGTGATTAAAAGGTT

hide sequence

RefSeq Acc Id:

XM_039100269 ⟹ XP_038956197

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	108,457,043 - 108,511,533 (-)	NCBI
mRatBN7.2	X	103,669,293 - 103,722,940 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001414534	(Get FASTA)	NCBI Sequence Viewer
	XP_006234316	(Get FASTA)	NCBI Sequence Viewer
	XP_006234317	(Get FASTA)	NCBI Sequence Viewer
	XP_038956197	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI60918	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000075626.1

RefSeq Acc Id:	XP_006234317 ⟸ XM_006234255
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2KB27 (UniProtKB/TrEMBL), A6HLS3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFPSTPYVPACMASQELSSTTSTTTTTTVTTNTTTTITSGFNLYLTPPASSPWLNNTGLINMAS LPSTMTVNSIVTPVMTYGPLDSMVNNWHYQLQEQEKHYFYQAHQFNVWNHALIETSNEIALLHN EVERVKRDQSRLEQELDLILLQQKELEHTLAPIEEFLKEQNGPLKLLYVNKEYEMIYRLAEVID ADLKRMSQDLKDIIIYLNSVIRPADASEPLEQICRILSAHLESLQWISHNSGIMHKKVEEVAKA FEEYRRKGQDAMNVAFE hide sequence

RefSeq Acc Id:	XP_006234316 ⟸ XM_006234254
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2KB27 (UniProtKB/TrEMBL), A6HLS3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFPSTPYVPACMASQELSSTTSTTTTTTVTTNTTTTITSGFNLYLTPPASSPWLNNTGLINMAS LPSTMTVNSIVTPVMTYGPLDSMVNNWHYQLQEQEKHYFYQAHQFNVWNHALIETSNEIALLHN EVERVKRDQSRLEQELDLILLQQKELEHTLAPIEEFLKEQNGPLKLLYVNKEYEMIYRLAEVID ADLKRMSQDLKDIIIYLNSVIRPADASEPLEQICRILSAHLESLQWISHNSGIMHKKVEEVAKA FEEYRRKGQDAMNVAFE hide sequence

Ensembl Acc Id:

ENSRNOP00000075626 ⟸ ENSRNOT00000088979

RefSeq Acc Id:	XP_038956197 ⟸ XM_039100269
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2KB27 (UniProtKB/TrEMBL), A6HLS3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001414534 ⟸ NM_001427605
- UniProtKB:	A0A0G2KB27 (UniProtKB/TrEMBL), A6HLS3 (UniProtKB/TrEMBL)

Protein Domains

Nucleoporin NSP1-like C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2KB27-F1-model_v2	AlphaFold	A0A0G2KB27	1-273	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564353	AgrOrtholog
BioCyc Gene	G2FUF-1548	BioCyc
Ensembl Genes	ENSRNOG00000057753	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000088979.2	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.170	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7458042	IMAGE-MGC_LOAD
InterPro	NSP1/NUP62	UniProtKB/TrEMBL
	Nucleoporin_NSP1_C	UniProtKB/TrEMBL
KEGG Report	rno:300923	UniProtKB/TrEMBL
MGC_CLONE	MGC:188661	IMAGE-MGC_LOAD
NCBI Gene	300923	ENTREZGENE
PANTHER	NUCLEOPORIN 62 C-TERMINAL-LIKE	UniProtKB/TrEMBL
	PTHR12084	UniProtKB/TrEMBL
Pfam	Nsp1_C	UniProtKB/TrEMBL
PhenoGen	Nup62cl	PhenoGen
RatGTEx	ENSRNOG00000057753	RatGTEx
UniProt	A0A0G2KB27	ENTREZGENE, UniProtKB/TrEMBL
	A6HLS3	ENTREZGENE, UniProtKB/TrEMBL
	B1H298_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Nup62cl	nucleoporin 62 C-terminal like	RGD1564353_predicted	similar to Nucleoporin 62 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1564353_predicted	similar to Nucleoporin 62 (predicted)	LOC300923	similar to Nucleoporin 62	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC300923	similar to Nucleoporin 62			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar