Dppa5al1 (developmental pluripotency associated 5A like 1) - Rat Genome Database

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Gene: Dppa5al1 (developmental pluripotency associated 5A like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Dppa5al1 (Ensembl: Dppa5)
Name: developmental pluripotency associated 5A like 1 (Ensembl:developmental pluripotency associated 5)
RGD ID: 1564306
Description: INTERACTS WITH methoxychlor; vinclozolin
Type: protein-coding
RefSeq Status: MODEL
Previously known as: developmental pluripotency-associated protein 5A-like; LOC311031; RGD1564306; similar to developmental pluripotency associated 5
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8357,725,040 - 57,725,781 (+)NCBIGRCr8
mRatBN7.2337,315,942 - 37,316,483 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl762,525,014 - 62,531,945 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl337,316,133 - 37,316,483 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0338,367,481 - 38,368,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl769,982,245 - 69,982,592 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl338,367,556 - 38,367,903 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0343,466,184 - 43,466,795 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4334,338,094 - 34,338,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera335,454,564 - 35,455,188 (+)NCBICelera
Cytogenetic Map3q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function
mRNA binding  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:25
Count of miRNA genes:25
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000049144
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1298073Cm13Cardiac mass QTL 132.5heart mass (VT:0007028)heart wet weight (CMO:0000069)32501391138192233Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)32749462144188411Rat
2313079Bss73Bone structure and strength QTL 731.5tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)32749462150302886Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
2313076Bss74Bone structure and strength QTL 7420.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)32749462150302886Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
2313093Bmd77Bone mineral density QTL 772.20.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)32749462150302886Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31831145447233430Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31831145447233430Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31831145447233430Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31831145447233430Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
2313101Bmd76Bone mineral density QTL 763.60.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)32749462150302886Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31831145447233430Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145447233430Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31831145447233430Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
2313049Bss72Bone structure and strength QTL 722.60.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)32749462150302886Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat


Expression


Sequence


RefSeq Acc Id: XM_229957   ⟹   XP_229957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8357,725,040 - 57,725,781 (+)NCBI
mRatBN7.2337,315,942 - 37,316,483 (+)NCBI
Rnor_6.0338,367,481 - 38,368,110 (+)NCBI
Rnor_5.0343,466,184 - 43,466,795 (+)NCBI
RGSC_v3.4334,338,094 - 34,338,444 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_229957 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000000215.3
  ENSRNOP00000038959.5
  ENSRNOP00000041925.4
  ENSRNOP00000071223.2
RefSeq Acc Id: XP_229957   ⟸   XM_229957
- UniProtKB: F1LWL9 (UniProtKB/TrEMBL),   F1LVJ7 (UniProtKB/TrEMBL),   F1LXK2 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
KH-like RNA-binding

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564306 AgrOrtholog
BioCyc Gene G2FUF-49721 BioCyc
Ensembl Genes ENSRNOG00000000199 UniProtKB/TrEMBL
  ENSRNOG00000029793 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000032335 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000060610 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000215.4 UniProtKB/TrEMBL
  ENSRNOT00000040010.5 UniProtKB/TrEMBL
  ENSRNOT00000049144.5 UniProtKB/TrEMBL
  ENSRNOT00000078193.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
InterPro KH_dom_type_1_sf UniProtKB/TrEMBL
  MOEP19_KH-like UniProtKB/TrEMBL
KEGG Report rno:299829 UniProtKB/TrEMBL
  rno:301101 UniProtKB/TrEMBL
  rno:311031 UniProtKB/TrEMBL
NCBI Gene 311031 ENTREZGENE
PANTHER DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER UniProtKB/TrEMBL
  DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED 5 PROTEIN UniProtKB/TrEMBL
Pfam MOEP19 UniProtKB/TrEMBL
PhenoGen Dppa5al1 PhenoGen
RatGTEx ENSRNOG00000000199 RatGTEx
  ENSRNOG00000029793 RatGTEx
  ENSRNOG00000032335 RatGTEx
  ENSRNOG00000060610 RatGTEx
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
UniProt F1LVJ7 ENTREZGENE
  F1LWL9 ENTREZGENE, UniProtKB/TrEMBL
  F1LXK2 ENTREZGENE, UniProtKB/TrEMBL
  F1M487_RAT UniProtKB/TrEMBL
UniProt Secondary F1LVJ7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Dppa5al1  developmental pluripotency associated 5A like 1  RGD1564306  similar to developmental pluripotency associated 5  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1564306  similar to developmental pluripotency associated 5   RGD1564306_predicted  similar to developmental pluripotency associated 5 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564306_predicted  similar to developmental pluripotency associated 5 (predicted)  LOC311031  similar to developmental pluripotency associated 5  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC311031  similar to developmental pluripotency associated 5      Symbol and Name status set to provisional 70820 PROVISIONAL