Rps27a-ps12 (ribosomal protein S27a, pseudogene 12)

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Gene: Rps27a-ps12 (ribosomal protein S27a, pseudogene 12) Rattus norvegicus

Analyze

Symbol:

Rps27a-ps12

Name:

ribosomal protein S27a, pseudogene 12

RGD ID:

1564290

Description:

Predicted to be involved in translation. Orthologous to human UBBP4 (ubiquitin B pseudogene 4); INTERACTS WITH acrylamide (ortholog); testosterone (ortholog).

Type:

pseudo (Ensembl: protein-coding)

RefSeq Status:

INFERRED

Previously known as:

Gm8430; LOC498837; predicted pseudogene 8430; RGD1564290; ribosomal protein S27-like 3; Rps27l3; similar to ribosomal protein S27a; Ubbp4; ubiquitin B pseudogene 4

RGD Orthologs

Human

Mouse

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UBBP4 (ubiquitin B pseudogene 4)	HGNC	Panther
Mus musculus (house mouse):	Gm8797 (predicted pseudogene 8797)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RPS27A (ribosomal protein S27a)	HGNC	Treefam
Homo sapiens (human):	PSMD12 (proteasome 26S subunit, non-ATPase 12)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	UBBP4 (ubiquitin B pseudogene 4)	Alliance	DIOPT (HGNC)
Drosophila melanogaster (fruit fly):	RpS27A	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPS31	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ubl-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)

Related Functional Gene:

Rps27a

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	24,242,836 - 24,243,530 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	24,242,880 - 24,243,492 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	24,370,879 - 24,371,572 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_WKY_Bbb_1.0	18	24,465,901 - 24,466,595 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	25,394,160 - 25,394,853 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	18	25,109,896 - 25,110,559 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	25,059,320 - 25,059,931 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	18	23,992,337 - 23,993,030 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

acrylamide (ISO)

testosterone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

modification-dependent protein catabolic process (IBA)

protein ubiquitination (IBA)

translation (IEA)

Cellular Component

cytosolic small ribosomal subunit (IBA)

Molecular Function

protein tag activity (IBA)

structural constituent of ribosome (IBA)

ubiquitin protein ligase binding (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Rps27a-ps12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	24,242,836 - 24,243,530 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	24,242,880 - 24,243,492 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	24,370,879 - 24,371,572 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_WKY_Bbb_1.0	18	24,465,901 - 24,466,595 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	25,394,160 - 25,394,853 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	18	25,109,896 - 25,110,559 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	25,059,320 - 25,059,931 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	18	23,992,337 - 23,993,030 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

UBBP4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	22,090,750 - 22,205,151 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	22,090,743 - 22,205,156 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p14 Ensembl	17	22,204,093 - 22,205,009 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	21,729,601 - 21,731,762 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	21,654,826 - 21,655,739 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	19,846,820 - 19,848,706 (+)	NCBI		Celera
Cytogenetic Map	17	p11.2	NCBI
HuRef	17	20,930,295 - 20,932,187 (+)	NCBI		HuRef
CHM1_1	17	21,792,310 - 21,794,202 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	22,756,789 - 22,866,794 (+)	NCBI		T2T-CHM13v2.0

Gm8797
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	5,815,953 - 5,816,355 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	5,815,866 - 5,816,355 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	5,750,893 - 5,751,295 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	5,750,806 - 5,751,295 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	5,750,803 - 5,751,296 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	5,733,878 - 5,734,370 (+)	NCBI		MGSCv36	mm8
Celera	3	5,821,129 - 5,821,622 (+)	NCBI		Celera
Cytogenetic Map	3	A1	NCBI
cM Map	3	1.96	NCBI

Variants

Variants in Rps27a-ps12
2 total Variants

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552968	Pigfal19	Plasma insulin-like growth factor 1 level QTL 19	11.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	18	1	25758124	Rat
9590248	Scort10	Serum corticosterone level QTL 10	19.71	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	1	25758124	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	30558703	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34291613	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34291613	Rat
61388	Bp2	Blood pressure QTL 2	3.23		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	1	35374722	Rat
9589153	Insul31	Insulin level QTL 31	7.15	0.05	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	18	1	42547119	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4207941	60377792	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5185858	40503530	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11941791	31393320	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	11941791	31393320	Rat
12904690	Cm129	Cardiac mass QTL 129		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	11944273	26548295	Rat
12904689	Cm128	Cardiac mass QTL 128		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	11944273	26548295	Rat
12904693	Am20	Aortic mass QTL 20		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	11944273	26548295	Rat
12904695	Kidm73	Kidney mass QTL 73		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	11944273	26548295	Rat
12904691	Cm130	Cardiac mass QTL 130		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	11944273	26548295	Rat
12904680	Bw189	Body weight QTL 189		0.019	body mass (VT:0001259)	body weight (CMO:0000012)	18	11944273	26548295	Rat
2301410	Bp317	Blood pressure QTL 317		0.004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944273	26548295	Rat
1331781	Scl28	Serum cholesterol level QTL 28	3.995		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	11944299	24797117	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944299	31359530	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	11944299	41122201	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944299	52293055	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	11944299	59330563	Rat
6903359	Bp355	Blood pressure QTL 355	3.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944544	59796478	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	14951337	59951337	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	18007599	63571040	Rat
1331735	Rf44	Renal function QTL 44	2.981		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	18	18234564	31359530	Rat
1331775	Bp235	Blood pressure QTL 235	3.201		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	18234564	31359530	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19278901	83218561	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	21372893	83213037	Rat
1641923	Colcr8	Colorectal carcinoma resistance QTL 8	3.1	0.0014	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	22066242	52293055	Rat

Markers in Region

RH128322

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	18	p12	UniSTS
Cytogenetic Map	14	q22	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NG_042112	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001060136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008772051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_574121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACYVU010000299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000027780 ⟹ ENSRNOP00000027780

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	24,242,880 - 24,243,492 (-)	Ensembl

RefSeq Acc Id:

XM_001060136 ⟹ XP_001060136

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Celera	18	23,992,356 - 23,993,016 (-)	NCBI

RefSeq Acc Id:

XM_008772051 ⟹ XP_008770273

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	25,394,170 - 25,394,839 (-)	NCBI

RefSeq Acc Id:

XM_008774107 ⟹ XP_008772329

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Celera	18	23,992,356 - 23,993,016 (-)	NCBI

RefSeq Acc Id:

XM_574121 ⟹ XP_574121

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	25,394,170 - 25,394,839 (-)	NCBI
Rnor_5.0	18	25,109,896 - 25,110,559 (-)	NCBI
RGSC_v3.4	18	25,059,320 - 25,059,931 (-)	RGD

Protein Sequences

RefSeq Acc Id:	XP_001060136 ⟸ XM_001060136
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_574121 ⟸ XM_574121
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_008772329 ⟸ XM_008774107
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_008770273 ⟸ XM_008772051
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSRNOP00000027780 ⟸ ENSRNOT00000027780

Protein Domains

Ubiquitin-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LU69-F1-model_v2	AlphaFold	F1LU69	1-150	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564290	AgrOrtholog
BioCyc Gene	G2FUF-8021	BioCyc
Ensembl Genes	ENSRNOG00000020492	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000027780.7	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000027780.8	UniProtKB/TrEMBL
Gene3D-CATH	6.20.50.150	UniProtKB/TrEMBL
InterPro	Ribosomal_S27a	UniProtKB/TrEMBL
	Ribosomal_zn-bd	UniProtKB/TrEMBL
	S27a-like_sf	UniProtKB/TrEMBL
	Ubiquitin-like_dom	UniProtKB/TrEMBL
	Ubiquitin-like_domsf	UniProtKB/TrEMBL
	Ubiquitin_dom	UniProtKB/TrEMBL
NCBI Gene	498837	ENTREZGENE
PANTHER	40S RIBOSOMAL PROTEIN S27A-RELATED	UniProtKB/TrEMBL
	UBIQUITIN	UniProtKB/TrEMBL
Pfam	Ribosomal_S27	UniProtKB/TrEMBL
	ubiquitin	UniProtKB/TrEMBL
PhenoGen	Rps27a-ps12	PhenoGen
PRINTS	UBIQUITIN	UniProtKB/TrEMBL
PROSITE	UBIQUITIN_2	UniProtKB/TrEMBL
SMART	Ribosomal_S27	UniProtKB/TrEMBL
	UBQ	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54236	UniProtKB/TrEMBL
	SSF57829	UniProtKB/TrEMBL
UniProt	F1LU69_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-07-18	Rps27a-ps12	ribosomal protein S27a, pseudogene 12	Rps27a-ps34	ribosomal protein S27a, pseudogene 34	Name and Symbol changed	629549	APPROVED
2022-07-18	Rps27a-ps34	ribosomal protein S27a, pseudogene 34	Ubbp4	ubiquitin B pseudogene 4	Name and Symbol changed	629549	APPROVED
2017-01-03	Ubbp4	ubiquitin B pseudogene 4	Rps27a-ps12	ribosomal protein S27a, pseudogene 12	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-05-18	Rps27a-ps12	ribosomal protein S27a, pseudogene 12	Rps27l3	ribosomal protein S27-like 3	Name and Symbol changed	629549	APPROVED
2013-03-05	Rps27l3	ribosomal protein S27-like 3	Gm8430	predicted pseudogene 8430	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-12	Gm8430	predicted pseudogene 8430	RGD1564290	similar to ribosomal protein S27a	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1564290	similar to ribosomal protein S27a	RGD1564290_predicted	similar to ribosomal protein S27a (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1564290_predicted	similar to ribosomal protein S27a (predicted)	LOC498837	similar to ribosomal protein S27a	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC498837	similar to ribosomal protein S27a			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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