Itpripl2 (ITPRIP like 2) - Rat Genome Database

Name: Itpripl2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Itpripl2 (ITPRIP like 2) Rattus norvegicus

Analyze

Symbol:

Itpripl2

Name:

ITPRIP like 2

RGD ID:

1564255

Description:

Predicted to be located in membrane. Orthologous to human ITPRIPL2 (ITPRIP like 2); INTERACTS WITH (+)-schisandrin B; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

inositol 1,4,5-triphosphate receptor interacting protein-like 2; inositol 1,4,5-triphosphate receptor-interacting protein-like 2; inositol 1,4,5-trisphosphate receptor interacting protein-like 2; inositol 1,4,5-trisphosphate receptor-interacting protein-like 2; LOC499253; RGD1564255; similar to CDNA sequence BC063749

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ITPRIPL2 (ITPRIP like 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther, Treefam
Mus musculus (house mouse):	Itpripl2 (inositol 1,4,5-triphosphate receptor interacting protein-like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Itpripl2 (ITPRIP like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ITPRIPL2 (ITPRIP like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ITPRIPL2 (ITPRIP like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Itpripl2 (ITPRIP like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ITPRIPL2 (ITPRIP like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ITPRIPL2 (ITPRIP like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Itpripl2 (ITPRIP like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ITPRIPL2 (ITPRIP like 2)	Alliance	DIOPT (HGNC)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	172,801,152 - 172,803,047 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	172,796,849 - 172,802,950 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	181,113,659 - 181,115,554 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	188,299,972 - 188,301,867 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	181,029,770 - 181,031,665 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	188,140,853 - 188,142,748 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	188,141,113 - 188,142,721 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	195,087,534 - 195,089,429 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	176,706,429 - 176,708,324 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	170,581,662 - 170,583,557 (-)	NCBI		Celera
Cytogenetic Map	1	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dimethylarsinic acid (ISO)

diquat (ISO)

diuron (ISO)

dorsomorphin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

gentamycin (EXP)

indometacin (ISO)

leflunomide (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylarsonic acid (ISO)

N-nitrosodiethylamine (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

phenobarbital (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

SB 431542 (ISO)

serpentine asbestos (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

temozolomide (ISO)

tetrachloromethane (EXP,ISO)

tetraphene (ISO)

thapsigargin (ISO)

thimerosal (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

urethane (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Itpripl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	172,801,152 - 172,803,047 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	172,796,849 - 172,802,950 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	181,113,659 - 181,115,554 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	188,299,972 - 188,301,867 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	181,029,770 - 181,031,665 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	188,140,853 - 188,142,748 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	188,141,113 - 188,142,721 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	195,087,534 - 195,089,429 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	176,706,429 - 176,708,324 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	170,581,662 - 170,583,557 (-)	NCBI		Celera
Cytogenetic Map	1	q35	NCBI

ITPRIPL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	19,113,964 - 19,121,629 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	19,113,932 - 19,121,629 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	19,125,286 - 19,132,951 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	19,032,783 - 19,040,453 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	18,273,132 - 18,280,831 (+)	NCBI		Celera
Cytogenetic Map	16	p12.3	NCBI
HuRef	16	17,662,673 - 17,670,372 (+)	NCBI		HuRef
CHM1_1	16	19,212,545 - 19,220,219 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	19,044,805 - 19,052,471 (+)	NCBI		T2T-CHM13v2.0

Itpripl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	118,084,334 - 118,091,198 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	118,084,334 - 118,091,198 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	118,485,111 - 118,491,975 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	118,485,111 - 118,491,975 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	125,628,625 - 125,635,489 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	118,277,558 - 118,283,124 (-)	NCBI		MGSCv36	mm8
Celera	7	118,437,794 - 118,444,656 (-)	NCBI		Celera
Cytogenetic Map	7	F1	NCBI
cM Map	7	63.44	NCBI

Itpripl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	2,985,994 - 2,987,601 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	2,981,507 - 2,987,633 (-)	NCBI	ChiLan1.0	ChiLan1.0

ITPRIPL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	16	24,901,957 - 24,909,141 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	19,188,159 - 19,196,265 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	19,218,710 - 19,225,849 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	19,218,758 - 19,220,365 (+)	Ensembl	panpan1.1		panPan2

ITPRIPL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	25,949,343 - 25,955,754 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	27,311,245 - 27,317,465 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	26,104,334 - 26,110,555 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	6	25,904,282 - 25,910,501 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	25,798,572 - 25,804,790 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	26,188,362 - 26,194,584 (+)	NCBI		UU_Cfam_GSD_1.0

Itpripl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	116,898,339 - 116,904,617 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	5,000,866 - 5,002,473 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936501	4,997,722 - 5,002,477 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ITPRIPL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	26,404,636 - 26,406,234 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	26,403,860 - 26,411,608 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ITPRIPL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	17,401,044 - 17,405,132 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	17,401,561 - 17,403,168 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	12,524,898 - 12,531,218 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Itpripl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	2,646,385 - 2,647,992 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	2,641,871 - 2,648,048 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Itpripl2
6 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	91
Count of miRNA genes:	84
Interacting mature miRNAs:	88
Transcripts:	ENSRNOT00000055106
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	115585465	172949803	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350408	181759564	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	123350408	182418476	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	123350408	182418476	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	123350408	182418476	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
71118	Thym1	Thymus enlargement QTL 1	10.17	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
724550	Thym3	Thymus enlargement QTL 3	7.82	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	136830018	181830018	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	143506580	212458660	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144017057	197814409	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	144267353	196383668	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
634315	Niddm45	Non-insulin dependent diabetes mellitus QTL 45	7.16		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	144267916	172949660	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144267916	174133260	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	149448574	221264292	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	201278233	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	201278233	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	151162512	201278233	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	151162512	201278233	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	151162766	225824951	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	151646613	196646613	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	154561505	199561505	Rat
1582204	Livw1	Liver weight QTL 1	3.6	0.0003	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	1	155422851	172949803	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	155866514	200866514	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	156677124	176484451	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	156677124	201278233	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	156677124	218753816	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	158633083	203633083	Rat
2292222	Bp307	Blood pressure QTL 307	3.06	0.0014	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	213533942	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164747424	209747424	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	164747424	209747424	Rat
737974	Bp161	Blood pressure QTL 161		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	164747558	181133855	Rat
2312558	Glom17	Glomerulus QTL 17	3.9	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	166532971	191278129	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	167909849	212909849	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169112897	197261052	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	169112897	197261052	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169537671	214537671	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	169537671	214537671	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	171310381	216310381	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	171629477	216629477	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	171629477	216629477	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	171629477	216629477	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	171629477	216629477	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	171629477	216629477	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	171629477	216629477	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	172609619	217609619	Rat

Markers in Region

D1Rat359

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	172,804,146 - 172,804,370 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	188,143,848 - 188,144,071	NCBI	Rnor6.0
Rnor_5.0	1	195,090,529 - 195,090,752	UniSTS	Rnor5.0
RGSC_v3.4	1	176,709,423 - 176,709,647	RGD	RGSC3.4
RGSC_v3.4	1	176,709,424 - 176,709,647	UniSTS	RGSC3.4
RGSC_v3.1	1	176,848,669 - 176,848,893	RGD
Celera	1	170,584,657 - 170,584,880	UniSTS
SHRSP x BN Map	1	86.8799	RGD
SHRSP x BN Map	1	86.8799	UniSTS
Cytogenetic Map	1	q35	UniSTS

D1Got364

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	172,804,853 - 172,805,015 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	188,144,555 - 188,144,716	NCBI	Rnor6.0
Rnor_5.0	1	195,091,236 - 195,091,397	UniSTS	Rnor5.0
RGSC_v3.4	1	176,710,131 - 176,710,292	UniSTS	RGSC3.4
Celera	1	170,585,364 - 170,585,525	UniSTS
Cytogenetic Map	1	q35	UniSTS

AW534215

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	172,801,194 - 172,801,363 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	188,140,896 - 188,141,064	NCBI	Rnor6.0
Rnor_5.0	1	195,087,577 - 195,087,745	UniSTS	Rnor5.0
RGSC_v3.4	1	176,706,472 - 176,706,640	UniSTS	RGSC3.4
Celera	1	170,581,705 - 170,581,873	UniSTS
RH 3.4 Map	1	1379.29	UniSTS
Cytogenetic Map	1	q35	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1		1		9					2	11	11
Low	2	43	56	41	10	41	8	11	74	33	26		8
Below cutoff											4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001127303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166746	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000055106

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	188,141,113 - 188,142,721 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099502 ⟹ ENSRNOP00000081031

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	172,796,849 - 172,802,950 (-)	Ensembl

RefSeq Acc Id:

NM_001127303 ⟹ NP_001120775

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	172,801,152 - 172,803,047 (-)	NCBI
Rnor_6.0	1	188,140,853 - 188,142,748 (-)	NCBI
Rnor_5.0	1	195,087,534 - 195,089,429 (-)	NCBI
RGSC_v3.4	1	176,706,429 - 176,708,324 (-)	RGD
Celera	1	170,581,662 - 170,583,557 (-)	RGD

Sequence:

show sequence

GCGCCCTGGGCCGCCCGGGCTCCCGGCATGTCCGTGCGGTACACGCTCAACCTGAGGGTCTTCT
GGCCCTTGGTGACCGGGCTGTGCACGGCGCTAGTGTGCCTCTACCATGCCCTACGCAGCAGCGA
GGGTGCCCGGGCCGAGCCCCCCGACGGCGCAGACAGCGGCTTCCCGCTGCTCAAGGTGGCTATC
CTTCTTCTCCTCTGCTACATCCTCCTACGATGTCGCCACACCATCCGCCAGCGCCTCTTGCCAG
GCTCTTCCCGCCCATGTGGCCATGCCAACTTCTCAGCCAGATCCTTGCAAGAGCCAGGCCTGAG
CATCTTGCTGGAGAGTTACTATGAGCACGAAGTGCGCCTATCGCCACATGTGCTAGGTCACAGC
AAGGCGCATGTGAGCCGGATCGTAGGGGAACTGGTGCAAGCTGGCCGAGCCCGAGGGTCTCCGG
GCCCCATCACCGGTGGAGCGCTGGCTTTGGCCTTCCGGGGAGACTTCATCCAGGTGGGCAGCGC
CTACGAACAGCATAAAATCCGGCGACCCGACAGCTTCGACGTGTTGGTGCCACTGAGACTCCCG
CCGCAGGTGGCGCTGGAGCCACGGAGCCTAGGGACTGAACCTGCTCTGACCCCGGCCTTCCGCA
GCTGCTTCGTGTGCACCCTCAAGGCACCGCCCTCGCCATCGGGGACCTCGACGGGCCAGTGGCA
TCGCGACTGCAAGCCCTTCGCTGAAGGCTTCTGTGTGGATGTGCAGGGCCGTCGCCACCTCTCA
GCTACCCTGGTGCTGCGCTGGTTCCAGGCGCACCTACAGCGCTCCTTGGCCACCGTGCGCTACA
GTTTGGAGGGTCGCTGTCGCGTCAGCCTGACCCCAGGGGGTCTGGAGCAGCCTCCCACCCTTCA
CATCCTTCCCTGCCGCACGGACTATGGCTGCTGCCGCCTTTCCATGGCCGTGCGCCTCATCCCG
GCTGTCCACCTGGGTGAAGGCGTCTTCCTTGTGGCACCGCCGCCACCACCCTCGCCTAGCGGGG
CTCTGTCAGAGCTCCCAGGTGGCCTGCGTGCTGAGGCACTGTGGGGTGTGAACACAGCACGTCA
GGAGCAGAAACTGCTGGGCTGGCTTCAGGAACGGGCGCCTCCAGGTGCCTGCTACCTCAAGTGC
CTGCAGCTGCTTAAGGCCCTTCGAGACTTGGGTGCCCGCGGGCTGGACCCGATGGCTGCTACAC
ACTGGGGACGCATCCTGTCCTCCTACATGCTCAAAACAGCGGTGCTCGAGGTGCTTCTGAATGA
GGGGGGCCCAACACCTAGCTGGGACGAGGCATACCTGAGTGAGTGCTTGGAGAAGTTGGTGAAG
TTCCTTAGGGACTGCCTGCTGCGACGCCGAGACCTCTTCCATTGTGTCCTAGGTCCGGCTGGGG
CAGCTGCCGAAGTTGGACCCCTGCCCAAGGTGCTGCGTGAGGCCCCTCCAGTTGACCTCCTGGC
ACCCTTCGACCAGCATGCCCGGGAGCTTGCAGCAGCGCGGTTACTGTCCACCTGGCGAAGGTTG
CCCCAGCTTCTCCAGGTCTATGGTGGTCCCCGTTACCTTGCCAGGTGTCCTGCACCCCGGAGTC
AACGCATCCAGGGCTTCCCGGAAGATGAACCATGAACACTGATTACACACCACTGACCAAATGC
CCCTTTCCCACGGATGAGAGCACCGATGGCAGCTAAATAACAGATGAGCTGTCCCAGGTGTTGG
AAAATTTGAAGGATGTCACAGGATTTGGTGGCACGAATGTTCTGTCCTAGGCTCCCTGGCCTAA
GATAGCAGTGGCATCTTCTGCAGACCTAGTAGAGTATCCTGGGTGGTCTTATACACCGATCTCT
CTGTCCCCCAAATTATTAAAAGCAATCATTTTTTATTTACAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001120775	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66746	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001120775 ⟸ NM_001127303

- UniProtKB:

B2RYE2 (UniProtKB/TrEMBL), A0A8I5ZS51 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSVRYTLNLRVFWPLVTGLCTALVCLYHALRSSEGARAEPPDGADSGFPLLKVAILLLLCYILL
RCRHTIRQRLLPGSSRPCGHANFSARSLQEPGLSILLESYYEHEVRLSPHVLGHSKAHVSRIVG
ELVQAGRARGSPGPITGGALALAFRGDFIQVGSAYEQHKIRRPDSFDVLVPLRLPPQVALEPRS
LGTEPALTPAFRSCFVCTLKAPPSPSGTSTGQWHRDCKPFAEGFCVDVQGRRHLSATLVLRWFQ
AHLQRSLATVRYSLEGRCRVSLTPGGLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGEGVF
LVAPPPPPSPSGALSELPGGLRAEALWGVNTARQEQKLLGWLQERAPPGACYLKCLQLLKALRD
LGARGLDPMAATHWGRILSSYMLKTAVLEVLLNEGGPTPSWDEAYLSECLEKLVKFLRDCLLRR
RDLFHCVLGPAGAAAEVGPLPKVLREAPPVDLLAPFDQHARELAAARLLSTWRRLPQLLQVYGG
PRYLARCPAPRSQRIQGFPEDEP

hide sequence

RefSeq Acc Id:

ENSRNOP00000081031 ⟸ ENSRNOT00000099502

Protein Domains

Mab-21-like HhH/H2TH-like

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564255	AgrOrtholog
BioCyc Gene	G2FUF-57690	BioCyc
Ensembl Genes	ENSRNOG00000036762	Ensembl
	ENSRNOG00000069633	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000081031	ENTREZGENE
	ENSRNOP00000081031.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000099502	ENTREZGENE
	ENSRNOT00000099502.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1410.40	UniProtKB/TrEMBL
	3.30.460.90	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5598710	IMAGE-MGC_LOAD
InterPro	INOS145TPRIP	UniProtKB/TrEMBL
	Mab-21_dom	UniProtKB/TrEMBL
	Mab-21_HhH/H2TH-like	UniProtKB/TrEMBL
KEGG Report	rno:499253	UniProtKB/TrEMBL
MGC_CLONE	MGC:188482	IMAGE-MGC_LOAD
NCBI Gene	499253	ENTREZGENE
PANTHER	CELL FATE DETERMINING PROTEIN MAB21-RELATED	UniProtKB/TrEMBL
	PTHR10656:SF9	UniProtKB/TrEMBL
Pfam	Mab-21_C	UniProtKB/TrEMBL
PhenoGen	Itpripl2	PhenoGen
PRINTS	INOS145TPRIP	UniProtKB/TrEMBL
SMART	Mab-21	UniProtKB/TrEMBL
UniProt	A0A8I5ZS51	ENTREZGENE, UniProtKB/TrEMBL
	B2RYE2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-10-19	Itpripl2	ITPRIP like 2	Itpripl2	inositol 1,4,5-trisphosphate receptor interacting protein-like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-08-02	Itpripl2	inositol 1,4,5-trisphosphate receptor interacting protein-like 2	Itpripl2	inositol 1,4,5-triphosphate receptor interacting protein-like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-09	Itpripl2	inositol 1,4,5-triphosphate receptor interacting protein-like 2	RGD1564255	similar to CDNA sequence BC063749	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1564255	similar to CDNA sequence BC063749	RGD1564255_predicted	similar to CDNA sequence BC063749 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1564255_predicted	similar to CDNA sequence BC063749 (predicted)	LOC499253	similar to CDNA sequence BC063749	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC499253	similar to CDNA sequence BC063749			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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